Ðe wò ƒuwo gbɔdzɔ eye wole veve sema? Mina míasrɔ̃ nu tso (Osteitis Fibrosa Cystica - OFC) sia ŋu!

Ðe nèsea veve kple vevesese ɣeaɖewoɣi le wò ŋutilã me, vevietɔ le wò ƒuwo mea? Alo ɖe nèsena le ɖokuiwò me be yeƒe ƒuwo le gbagbãm le nu suetɔ kekeake gɔ̃ hã mea? Ðewohĩ nɔnɔme aɖe le megbe na nusiawo si ŋu míeƒoa nu tsoe fũ o, gake ele vevie be míanya. Nɔnɔme mawo dometɔ ɖekae nye `(Osteitis Fibrosa Cystica - OFC)`. Togbɔ be ŋkɔ sia adze nu sesẽ vie hã la, mina míaɖe eme bɔbɔe.

Nukae nye Osteitis Fibrosa Cystica (OFC) ƒe dɔléle?

Kpuie ko la, `(Osteitis Fibrosa Cystica - OFC)` nye dɔléle si mebɔ o si gblẽa nu le míaƒe ƒuwo ŋu. Edo ƒome kple parathyroid lãkusi siwo le míaƒe ŋutilã me tẽ. Èse nu tso lãkusi si woyɔna be thyroid gland ŋu kpɔ. Parathyroid gland ene siawo le megbe nɛ. Lãmetsi siawo wɔa lãmetsi si woyɔna be parathyroid hormone (`Parathyroid Hormone - PTH`) .

`(PTH)` lãmetsi sia le vevie ŋutɔ be míaƒe ƒuwo nasẽ eye woanɔ lãmesẽ me. Ekpena ɖe ame ŋu hã be woaɖu calcium ƒe agbɔsɔsɔ si le ʋua me dzi. Gake, bu eŋu kpɔ, nukae adzɔ ne wowɔ `(PTH)` lãmetsi sia wògbɔ eme, si fia be wowɔe wògbɔ eme? Ɣemaɣie kuxia dzea egɔme. Le `(PTH)` ma si sɔ gbɔ ta la, le esi teƒe be woado ŋusẽ ƒuwo la, wodzea gbɔdzɔgbɔdzɔ gɔme vivivi . Le ɣeyiɣi aɖe megbe la, ƒuawo ƒe nɔnɔme ate ŋu atrɔ, eye nuwo abe dowo (abe ʋuʋudedi siwo me tsi yɔ fũ ene) hã ate ŋu adzɔ ɖe eme.

PTH si sɔ gbɔ alea ate ŋu ana calcium ƒe agbɔsɔsɔ nadzi ɖe edzi le ʋua me, si ana ayiku me kpewo nado, ʋusɔgbɔdɔ (ʋusɔgbɔdɔ), kple dzi ƒe dɔmawɔmawɔ nyuie.

Wotsɔ ŋkɔ bubu geɖewo yɔa nɔnɔmea be `(OFC)`. Ðewohĩ èse ŋkɔ siawo kpɔ:

• ``Von Recklinghausen ƒe ƒu ƒe dɔléle''.
• `Ƒu me dɔléle si nye fibrosa`
• `Cystica si wotsɔ ƒo ƒui`
• `Ƒumeŋusẽ ƒe dɔlékui si woyɔna be fibrosa`
• Ƒumeŋuɖui si ƒe amadede nye aŋutiɖiɖi . Mègavɔ̃ le ŋkɔ sia ta o. Togbɔ be wogblɔ be `(Tumor)` hã ​​la, menye ``Cancerous`` ye o. Wozã ŋkɔ sia elabena amesiwo ŋu `(OFC)` le la ƒe teƒeteƒewo nyea blɔ siwo dzena le ʋu ƒe dodo kple ka siwo le woƒe ƒuwo me ta. Gake le nyateƒe me la, menye kansa `(Tumor)` ye o.

Nya siwo nye "(Osteitis Fibrosa Cystica)" gɔmee nye nane abe 'ƒu ƒe ʋuʋu kple ƒu ƒe wɔwɔme' ene. Eyata ne `(PTH)` ƒe agbɔsɔsɔ dzi ɖe edzi la, ƒuawo ateŋu agblẽ ɣesiaɣi. Ke ne wokpɔ nɔnɔme sia si woyɔna be `(Hyperparathyroidism)` (i.e. `(PTH)` ƒe wɔwɔ fũu akpa) dze sii eye wodae kaba la, woateŋu ada `(OFC)` nɔnɔmea alo axe mɔ ɖe enu be wòagadzɔ o.

Aleke gbegbee nɔnɔme sia (OFC) bɔe?

Fifia ɖewohĩ ànɔ alesi gbegbe dɔléle sia bɔe ŋu bum. Le nyateƒe me la, ƒã ŋutɔ le dukɔ siwo me lãmesẽnyawo gbɔ kpɔkpɔ nyuie le me . Le kpɔɖeŋu me, le United States gɔ̃ hã la, amesiwo ŋu hyperparathyroidism le dometɔ siwo mede 5% o la xɔa OFC. Wokpɔnɛ zi geɖe le amesiwo ŋu hyperparathyroidism sesẽ le siwo womewɔ atike na o ɣeyiɣi didi aɖe la ŋu.

Gake tsã la, esia bɔ wu sã. Anɔ abe ƒe blaatɔ̃ enye sia la, ƒumedɔ sia nɔ amesiwo ŋu ``Hyperparathyroidism'' le la dometɔ siwo ade 69% ŋu. Gake esi atikewɔwɔ ŋuti dzɔdzɔmeŋutinunya le ŋgɔ yim, vevietɔ esi ``Ʋudodokpɔ edziedzi'' va ta la, wote ŋu de dzesi nɔnɔme siawo eye woda wo kaba wu. Ðe ema menye nu gã aɖeke oa?

Nukae nye nɔnɔme sia (OFC) ƒe dzesiwo?

Enyo, azɔ mina míakpɔ dzesi siwo ate ŋu ado mo ɖa le nɔnɔme si nye `(Osteitis Fibrosa Cystica)` me ɖa.

Dzesi vevitɔwoe nye:

• Ƒu ƒe vevesese . Esiae nye nu gbãtɔ si ame akpa gãtɔ sena le wo ɖokui me. Ɣeaɖewoɣi la, ate ŋu ave ame gɔ̃ hã ne èka asi ƒua ŋu.
• Nusiwo gbagbã . Ƒuwo, vevietɔ esiwo le abɔ, afɔ, alo akɔta, te ŋu gbãna bɔbɔe. Ne wodze anyi vie gɔ̃ hã ate ŋu agbã ƒu.

Le nɔnɔme sia ƒe gɔmedzedze la, dzesi siwo gbɔna hã ateŋu adze (esiawo ateŋu anye ``Hyperparathyroidism'' ƒe dzesiwo hã):

• Ðeɖiteameŋu ƒe seselelãme ɣesiaɣi (`Ðɖiteameŋu`).
• Gbɔdzɔgbɔdzɔ.
• Aɖuɖɔtoe kple ʋuʋudedi.
• Miléle.
• Aɖuɖɔtoe geɖe dodo wu alesi wòle dzɔdzɔmee (`Polyuria`). Esia fia be ele be woayi nugododeƒe zi geɖe.

Ne dzesi siawo le ŋuwò la, mègatso nya me le ɖokuiwò si be, "Oo, esia nye `(OFC)' o." Elabena dzesi siawo ate ŋu anɔ dɔléle bubuwo hã me. Gake ele vevie ŋutɔ be nànya nusiawo eye nàgblɔe na ɖɔkta.

Nukae nye nusiwo gbɔ (OFC) tsona?

Nukae hea Osteitis Fibrosa Cystica vɛ? Abe alesi megblɔe va yi ene la, nusi koŋ gbɔ esia tsonae nye Hyperparathyroidism si womeda dɔ na o . Eyae nye be míaƒe Parathyroid lãkusiwo wɔa PTH fũ akpa. Esia ate ŋu adzɔ le mɔ vevi eve nu:

1. Primary Hyperparathyroidism: Esia tsoa kuxi aɖe si le wò parathyroid glands ŋu gbɔ. Lãmenugbagbevi siawo ate ŋu anye kansa (kansa) alo woƒe tsitsi si menye kansa o (abe adenoma ene) si le PTH wɔm fũ akpa. Alo ate ŋu anye be lãkusi eneawo katã nalolo (hyperplasia) eye woawɔ lãmetsiŋusẽ geɖe akpa.

2. Secondary Hyperparathyroidism: Esia dzɔna le lãmesẽkuxi bubu aɖe ta. Le kpɔɖeŋu me, ne ayikudɔ si nɔa anyi didi le ame aɖe ŋu la, calcium kple vitamin D ƒe dadasɔ le eƒe ŋutilã me gblẽna. Emegbe le esia ta la, parathyroid lãkusiwo dzea PTH geɖe wɔwɔ gɔme. Azɔ hã, ne vitamin D ƒe agbɔsɔsɔ si mede ame dzi o vevie la, calcium si le ʋu me dzi ɖena kpɔtɔna, eyata parathyroid glands wɔa dɔ sesĩe wu be calcium ƒe agbɔsɔsɔ nadzi ɖe edzi. Ɣemaɣi la, PTH lãmetsiŋusẽa dzina ɖe edzi, eye le ɣeyiɣi aɖe megbe la, Osteitis Fibrosa Cystica ate ŋu adze ame dzi.

Bu eŋu kpɔ, ayiku me kuxiwo nɔ fu ɖem na mía nyruiyɔvi Kamala ɣeyiɣi didi aɖee nye sia. Meno atike si sɔ na esia o. Le ɣeyiɣi aɖe megbe la, eƒe `(Parathyroid)` lãkusiwo, siwo nɔ agbagba dzem be yewoaɖu calcium si le eƒe ŋutilã me dzi la, te `(PTH)` wɔwɔ geɖe wu alesi wòle be woawɔe. Mlɔeba la, nyruiyɔvi Kamala va xɔ `(OFC)` kpe ɖe ƒu ƒe vevesese ŋu. Èse kadodo si le wo dome gɔmea?

Nukawoe nye kuxi siwo ate ŋu ado tso (OFC) me?

Kuxi vevitɔ siwo dona tso hyperparathyroidism kple OFC si womeda dɔ na o me la tso ƒuwo gbɔ. Esia fia vevesese, ƒu ƒe gbagbã (nɔnɔme ƒe tɔtrɔ), kple ƒu ƒe gbagbã bɔbɔe . Esiawoe nye nu siwo dzena enumake. Ame aɖe ƒe kɔkɔme gɔ̃ hã ate ŋu aɖiɖi.

Gake tsɔ kpe ɖe esia ŋu la, kuxi bubuwo ate ŋu ado mo ɖa. Woawoe nye:

• Ayiku me kpewo ƒe wɔwɔme.
• Ayiku ƒe dɔmawɔmawɔ nyuie.
• Ŋusẽ si mebɔ o, ɖeɖiteameŋu ɣesiaɣi.
• Ƒodo ƒe vevesese.
• Susu me kuxiwo abe blanuiléle ene.
• Ŋkuɖodzi kple susu ƒe kuxiwo.

Kpɔ afisi kuxi si dze egɔme tso teƒe ɖeka ate ŋu ayi ɖa. Kuxi aɖe si le míaƒe ŋutilã ƒe ɖoɖo aɖe me ate ŋu akpɔ ŋusẽ ɖe ɖoɖo bubuwo hã dzi. Esia tae dɔlélea didi kaba kple edada le vevie ɖo.

Aleke wowɔa dea dzesi OFC?

Enyo, azɔ aleke ɖɔkta awɔ akpɔ nɔnɔme sia `(Osteitis Fibrosa Cystica)`?

Gbã la, wò ɖɔkta awɔ wò lãmesẽ ŋutinya tsitotsito . Abia wò ɣeyiɣi didi si dzesi siawo le ŋuwò, nenye be atikewɔwɔ me dɔléle bubuwo (abe ayikudɔ ene) le ŋuwò si ate ŋu akpɔ ŋusẽ ɖe wò PTH ƒe agbɔsɔsɔ dzi, kple atike siwo nèzãna hã. Emegbe, woawɔ ŋutilãmedodokpɔ atsɔ akpɔe ɖa be ƒuwo le veve sem, woƒe lãme le vevem, alo woƒe lãme gblẽ hã.

Be ɖɔktawo naɖo kpe dɔlélea dzi la, woate ŋu azã dodokpɔwo abe:

• Ʋudodokpɔ: Esiawo léa ŋku ɖe lãmetsiŋusẽ kple mineral ƒe dadasɔ ŋu. Etɔxɛe la, woléa ŋku ɖe parathyroid hormone (PTH) ƒe agbɔsɔsɔ, calcium ƒe agbɔsɔsɔ, phosphorus ƒe agbɔsɔsɔ, vitamin D ƒe agbɔsɔsɔ, kple alkaline phosphatase (enzyme si dona tso ƒuwo me) ŋu. Le OFC me la, PTH kple alkaline phosphatase ƒe agbɔsɔsɔ ateŋu asɔ gbɔ ŋutɔ.
• Aɖuɖɔtoe dodokpɔ: Àte ŋu akpɔ calcium agbɔsɔsɔme si le wò aɖuɖɔ me hã.
• Nɔnɔmetatawo ɖeɖe ƒe dodokpɔwo:
• X-ray: Esiawo ate ŋu aɖe alesi ƒuawo le suee, nuwo abe ƒunukpeƒetetedɔ ene, kple nenye be ƒuawo ƒe gbagbã sue aɖe ŋutɔ (microfractures) alo tɔtrɔ siwo ɖe dzesi le ƒuawo ŋu (abe subperiosteal resorption ene) afia.
• CT Scans (`CT - Computed Tomography scans`) alo MRI Scans (`MRI - Magnetic Resonance Imaging scans`): Esiawo ɖea ƒuawo ƒe nɔnɔme fiana tsitotsito wu X-ray.

Nukae nye atikewɔwɔ na (OFC)?

Enyo, azɔ mina míaƒo nu tso atikewɔwɔ na `(Osteitis Fibrosa Cystica)` ŋu. Atikewɔwɔa nɔ te ɖe `(Hyperparathyroidism)` si he `(OFC)` ƒe ƒomevi kple eƒe sesẽ dzi.

• Ne hyperparathyroidism gbãtɔ tso:
• Zi geɖe la, ne nusi gbɔ `(OFC)` nɔnɔme sia tso nye `(Parathyroid)` lãkusi ƒe dɔwɔwɔ si mesɔ o (abe dɔdzẽ ene) la, atikewɔwɔ si wozãna ɖaa enye be woawɔ dɔ na lãkusia alo lãkusia ƒe akpa aɖe (`Parathyroidectomy`) . Amekoko sia ateŋu atɔ te ƒuwo ƒe ƒuƒu eye wòagbugbɔ ƒu siwo gblẽ xoxo la dometɔ aɖewo aɖo anyi (`remineralization`). Zi geɖe la, `(Parathyroid)` lãkusi ene le mía si. Eyata ne woɖe lãkusi si me kuxi le la ɖa la, lãkusi susɔeawo ate ŋu awɔ `(PTH)` lãmetsi si ŋutilãa hiã.

• Le amesiwo mate ŋu awɔ dɔ na o alo amesiwo ŋu secondary hyperparathyroidism le gome la:
• Nusi gbɔ wòtso dada: Le kpɔɖeŋu me, ne vitamin D ƒe anyimanɔmanɔ gbɔe wòtso la, wonaa vitamin D kpeɖeŋutɔ. Ne ayikudɔe la, wodaae nyuie.
• Calcimimetics: Atike siawo srɔ̃a calcium si le wò ʋu me. Wo "blea" wò parathyroid gland be wòawɔ PTH si mesɔ gbɔ o. Cinacalcet nye atike mawo dometɔ ɖeka.
• Bisphosphonates: Atike siawo wɔa dɔ to ƒu ƒe gbagbã dzi ɖeɖe kpɔtɔ me. Zi geɖe la, woŋlɔa wo na amesiwo ŋu ƒumeŋuɖui le. Gake woate ŋu akpe ɖe amesiwo ŋu OFC le hã ŋu le ɣeyiɣi kpui aɖe me, vevietɔ be woado ŋusẽ ƒuwo hafi woawɔ dɔ na wo.
• Vitamin D kple calcium kpeɖeŋutɔ: Wonaa esiawo ne ehiã. Gake ne calcium ƒe agbɔsɔsɔ le ʋu me sɔ gbɔ la, womenaa calcium kpeɖeŋutɔ o.

Nukae nye mɔkpɔkpɔ na (OFC) ƒe ɖoƒe?

Nukae nye mɔkpɔkpɔ na `(OFC)` nɔnɔme sia? Le nyateƒe me la, ne wokpɔ egbɔ nyuie eye wodae nyuie la, woate ŋu ado tso eme nyuie . Atikewɔwɔ ateŋu atɔ te ƒuwo ƒe ƒuƒu eye wòado ŋusẽ ƒuawo (`remineralize`). Ƒu siwo gbã ate ŋu ada gbe le ame ŋu eye wòaɖe vevesese dzi akpɔtɔ. Gake ne ƒuawo gblẽ vevie la, ɖewohĩ womahaya keŋkeŋ o.

Ðe woate ŋu axe mɔ ɖe (OFC) nua?

Ðe wòanya wɔ be woaxe mɔ ɖe nɔnɔme sia `(Osteitis Fibrosa Cystica)` ƒe dzɔdzɔ nua? Ẽ, anya wɔ vaseɖe afi aɖe. Nu vevitɔ enye be woade dzesi nɔnɔme si nye `(Hyperparathyroidism)` kaba ahadae.

• Ele vevie ŋutɔ be woado ʋu kpɔ edziedzi , vevietɔ ne afɔkuwo abe ayikudɔ ene le ŋuwò. Esia akpe ɖe ŋuwò nàde dzesi tɔtrɔ ɖesiaɖe si ava wò ʋu me calcium kple PTH ƒe agbɔsɔsɔ me hafi wòagblẽ nu le ŋuwò vevie.
• Azɔ hã, ƒo nu kple wò ɖɔkta eye nàlé calcium kple vitamin D ƒe agbɔsɔsɔ nyui me ɖe asi.Wɔ nusi wòle be nàwɔ. Le kpɔɖeŋu me, ne èle nuto si me ɣe ƒe keklẽ mesɔ gbɔ ɖo le dzomeŋɔli o me la, ahiã be nàno vitamin D kpeɖeŋutɔ. Wò ɖɔkta agblɔ alesi nàwɔ akpɔ nunyiame siwo nèhiã tso nuɖuɖu siwo nèɖuna me hã na wò.

Ðo ŋku edzi be zi alesi wokpɔ nɔnɔme si nye `(Hyperparathyroidism)` dze sii kaba eye wodae la, zi nenemae wòate ŋu adzɔ be `(Osteitis Fibrosa Cystica)` nadze edzi o.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne ƒu le veve sem, le veve sem, alo ƒu aɖe si se le ɖokuiwò me be yeagbã , yi ɖɔkta gbɔ enumake. Azɔ hã, ne hyperparathyroidism (abe ɖeɖiteameŋu, ʋuʋudedi, kple aɖuɖɔtoe enuenu) ƒe dzesi gbãtɔ siwo megblɔ va yi dometɔ aɖe le ŋuwò la, gblɔ wo na wò ɖɔkta . Ne hyperparathyroidism le ŋuwò xoxo la, anyo be nàdo wò ʋu kpɔ edziedzi be woakpɔ wò calcium kple PTH ƒe agbɔsɔsɔ, abe alesi wò ɖɔkta kafui ene.

Nya kawoe wòle be mabia nye ɖɔkta?

Ne wokpɔe be `(Osteitis Fibrosa Cystica)` le ŋuwò la, anyo be nàbia nya siawo wò ɖɔkta:

• Aleke gbegbe nye nɔnɔmea gblẽe?
• Atikewɔwɔmɔnu kawoe le asinye? Viɖe kple kuxi kawoe le wo dometɔ ɖesiaɖe ŋu?
• Ðe wònyo be mano kpeɖeŋutɔtikewoa? Nu ka ƒomevie?
• Ðe wòahiã be woawɔ dɔ nam? Ne nenemae la, ke nukae mate ŋu akpɔ mɔ na le ema megbe?
• Tɔtrɔ kawoe mate ŋu awɔ le nuɖuɖu me si akpe ɖe ŋunye?
• Aleke nɔnɔme sia akpɔ ŋusẽ ɖe nye gbesiagbegbenɔnɔ dzii?

Mlɔeba la, nya vevi ʋɛ aɖewo

Eyata, ele nam be magblɔ nya sia na mi. Ƒu siwo gbɔdzɔ kple vevesese ate ŋu akpɔ ŋusẽ gã aɖe ɖe míaƒe gbesiagbegbenɔnɔ dzi. Ne wò ƒuwo gbãna bɔbɔe la, àte ŋu ase le ɖokuiwò me gɔ̃ hã be yeadzo le dɔwɔna aɖewo dzi. Ne dzesiwo abe ɖeɖiteameŋu, gbɔdzɔgbɔdzɔ, ʋuʋudedi, kple aɖuɖɔtoe enuenu le ŋuwò la, ateŋu anye ``Hyperparathyroidism`` alo eƒe kuxi ``OFC``.

Ne dzesi siawo dometɔ aɖe le ŋuwò la, taflatse yi ɖɔkta gbɔ kaba. Zi alesi nède dzesi dɔlélea hedae kaba la, zi nenemae màte ŋu agblẽ nu le wò ƒuwo ŋu boo o. Wò lãmesẽ le vevie na wò ŋutɔ. Eyata lé be nɛ.

` Ƒumeŋuɖui Fibrosa Cystica, OFC, Ƒumedɔléle, Parathyroid, PTH Lãmetsiŋusẽ, Hyperparathyroidism, Ƒumeveve