Ðe wò pituitary lãmetsiwo katã mebɔ oa? Mina míaƒo nu tso panhypopituitarism ŋu!

Ɣeaɖewoɣi la, nuwo mewɔa dɔ le míaƒe ŋutilã me abe alesi míekpɔ mɔe ene o, alo? Lãmetsiŋusẽwo nye dɔla vevi aɖe ŋutɔ ƒe ƒuƒoƒo aɖe si kpɔa gome le nuwɔna ɖesiaɖe kloe me le míaƒe ŋutilã me. Ne kuxi aɖe le lãmetsiŋusẽ sia ŋu la, ate ŋu agblẽ nu le míaƒe agbemeŋkekewo katã ŋu. Egbea míele nu ƒom tso nɔnɔme aɖe si mebɔ o si wòle be amesiame nanya ŋu. Emae nye panhypopituitarism.

Nukae nye Panhypopituitarism?

Kpuie ko la, panhypopituitarism nye nɔnɔme si mebɔ o si me pituitary gland, si nye lãkusi sue aɖe si le míaƒe ahɔhɔ̃ me, mewɔa lãmetsiŋusẽ siwo katã wòwɔna la wòdea edeƒe o alo womewɔa dɔ nyuie o. "Pan" ƒe akpaa gɔmee nye "katã." Nɔnɔme sia ate ŋu adze vidzĩwo, ɖeviwo, kple ame tsitsiwo dzi.

Fifia ɖewohĩ èle eŋu bum be, "Nukae nye lãmetsiŋusẽ siawo? Nukatae wole vevie nenema gbegbe ɖo?" Enyo, mina míalé ŋku ɖe ema ŋu.

Lãmetsiŋusẽwo le abe dɔla siwo le míaƒe ŋutilã me ene. Wonye atike tɔxɛwo. Wotoa míaƒe ʋu me hetsɔa gbedasiwo yia ŋutinu vovovowo, lãmekawo, kple lãmenugbagbevi bubuwo gbɔ. Wowɔa ɖoɖo, si fia be wokpɔa ŋusẽ ɖe míaƒe ŋutilã ƒe nuwɔna vovovowo dzi hewɔa ɖoɖo ɖe wo ŋu, hegblɔna na wo be "woawɔ esia, awɔe le ɣeyiɣi sia me, awɔe alea."

Míaƒe pituitary gland ƒe lolome anɔ abe pea ene. Enɔa míaƒe ahɔhɔ̃a ƒe gɔme, le hypothalamus te tututu. (Hypothalamus nye ahɔhɔ̃a ƒe dɔwɔƒe vevi aɖe si kpɔa nu vevi geɖe dzi, siwo dometɔ aɖewoe nye míaƒe lãmeka siwo wɔa dɔ le wo ɖokui si.) Togbɔ be eƒe lolome le sue hã la, pituitary gland wɔa akpa vevi aɖe ŋutɔ le míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ me. Eyae nye be pituitary hormone siawoe kpɔa nu geɖe dzi le míaƒe ŋutilã me, abe lãmenugbagbeviwo ƒe dɔwɔwɔ, tsitsi, kple vidzidzi ene.

Zi geɖe la, míaƒe ŋutilã ɖɔa lãmetsi siawo ƒe agbɔsɔsɔ ɖo nyuie. Gake ne lãmetsi siawo dometɔ aɖe ɖiɖi akpa la, ate ŋu ahe dzesi kple lãmesẽkuxi vovovowo vɛ. Panhypopituitarism nye ne lãmetsi siwo katã pituitary gland wɔna la bɔbɔ akpa, si hea dzesi vovovowo vɛ.

Vovototo kae le Panhypopituitarism kple Hypopituitarism dome?

Ŋkɔ eve siawo ɖi wo nɔewo vie, eyata woate ŋu atɔtɔ ame. Bu eŋu kpɔ, hypopituitarism nye nɔnɔme si me lãmetsiŋusẽ ɖeka alo esi wu nenema tsoa pituitary gland gbɔ. Panhypopituitarism nye nya tɔxɛ aɖe si me kɔ wu le nya ma ke me. Eyae nye be panhypopituitarism nye lãmetsiŋusẽ siwo katã pituitary gland wɔna ƒe anyimanɔmanɔ. Nya "pan" gɔmee nye "katã", eyata eɖe nɔnɔme sia me.

Lãmetsiŋusẽ kawoe pituitary gland la wɔna?

Lãmetsiŋusẽ ƒomevi vovovowo li siwo míaƒe lãkusi si woyɔna be pituitary gland wɔna eye woɖea wo ɖe go (si woɖena ɖe go). Dɔ aɖe koŋ le wo dometɔ ɖesiaɖe si. Mina míalé ŋku ɖe nusiwo wonye ŋu:

• Adrenocorticotropic hormone (ACTH alo corticotropin): Esia ʋãa míaƒe adrenal glandwo be woawɔ lãmetsi aɖe si woyɔna be cortisol. Wogayɔa cortisol sia be ‘nuteɖeamedzi ƒe lãmetsi’. Ele vevie ŋutɔ na ʋu ƒe sisi kple sukli ƒe agbɔsɔsɔ le ʋu me dzi ɖuɖu.
• Lãmetsiŋusẽ si doa ŋusẽ azi (FSH): Lãmetsi sia kpena ɖe ŋutsuwo ƒe tsinyenye ƒe wɔwɔme ŋu eye wòʋãa nyɔnuwo ƒe azigolowo be woawɔ lãmetsi si nye estrogen eye woatsi.
• Tsitsi ƒe lãmetsi (GH): Abe alesi ŋkɔa ɖee fia ene la, ele vevie na ɖeviwo ƒe tsitsi. Ekpena ɖe ame tsitsiwo hã be lãmekawo kple ƒuwo nanɔ lãmesẽ me, eye wòkpɔa ŋusẽ ɖe ŋutilã me ami ƒe mama dzi. GH hã kpɔa gome le míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ me.
• Luteinizing hormone (LH): LH hiã be wòaʋã azigolo le nyɔnuwo me eye wòana ŋutsuwo nawɔ testosterone.
• Prolactin: Lãmetsi sia doa ŋusẽ no me notsi wɔwɔ le vidzĩ dzidzi vɔ megbe. Ate ŋu akpɔ ŋusẽ ɖe nyɔnuwo ƒe dzinukpɔkpɔ kple vidzidzi kple gbɔdɔdɔ ƒe dɔwɔwɔ le ame tsitsiwo hã dzi.
• Thyroid-stimulating hormone (TSH): Esia ʋãa míaƒe thyroid gland be wòawɔ thyroid hormone, siwo kpɔa lãmenugbagbeviwo ƒe dɔwɔwɔ, ŋusẽ, kple lãmekawo ƒe dɔwɔwɔ dzi.

Tsɔ kpe ɖe esiawo ŋu la, lãkusia dzraa lãmetsiŋusẽ eve bubuwo ɖo heɖea wo ɖe go ne ehiã. Gake hypothalamus ye wɔa esiawo:

• Lãmetsiŋusẽ si tsia tsinyegoe me (ADH alo vasopressin): Lãmetsi sia naa tsi kple sodium (dze) ƒe agbɔsɔsɔ si le míaƒe ŋutilã me la nɔa ɖoɖo nu.
• Oxytocin: Ekpena ɖe nyɔnuwo ŋu be woƒe vidzidɔ natsi le vidzidzi me, eye wòkpena ɖe no me notsi hã ŋu be wòana. Wogblɔ hã be lãmetsi sia kpɔa ŋusẽ ɖe kadodo si le dzilawo kple vidzĩwo dome dzi.

Kpɔ ɖa, dɔ vevi ka gbegbee nye si pituitary gland sue sia wɔna! Eyata lãmetsiŋusẽ siawo katã dzi ɖeɖe kpɔtɔ ate ŋu akpɔ ŋusẽ gã aɖe ɖe ame dzi.

Amekae panhypopituitarism ƒe nɔnɔme sia gblẽa nu le wu?

Le nyateƒe me la, nɔnɔme sia si woyɔna be panhypopituitarism ate ŋu adzɔ le amesiame me, le ƒe ɖesiaɖe me. Ƒe ƒe seɖoƒe alo akpa aɖeke meli koŋ o.

Aleke gbegbee nɔnɔme sia bɔe?

Esia nye nɔnɔme si mebɔ kura o . Le xexea me godoo la, ame ene koe wogblɔna be dɔléle sia le ame akpe alafa ɖesiaɖe me ƒe sia ƒe. Eya ta, ebɔ be míagase nu geɖe tso eŋu o.

Ðe Panhypopituitarism ate ŋu ade ame ƒe agbe afɔku mea?

Ẽ, le go aɖewo me la, nɔnɔme sia ate ŋu ade ame ƒe agbe afɔku me. Vevietɔ ne lãmetsi si nye adrenocorticotropic hormone (ACTH) le sue ŋutɔ la, ate ŋu anye afɔku.

Nusitae nye be ACTH ƒe anyimanɔmanɔ ate ŋu ahe nɔnɔme kpata aɖe si woyɔna be adrenal crisis vɛ . Wogayɔa esia be ``acute cortisol insufficiency''. ACTH ye kpɔa míaƒe cortisol ƒe agbɔsɔsɔ dzi. Eyata ne ACTH megali o la, womewɔa cortisol o. Adrenal ƒe kuxi sia nye dɔléle si hiã be woakpɔ egbɔ enumake eye ate ŋu ade ame ƒe agbe afɔku me gɔ̃ hã.

Adrenal crisis ƒe dzesiwo ate ŋu anye:

• Asrã
• Gbɔdzɔgbɔdzɔ sesẽ aɖe
• Tɔtɔ (gɔmesese manɔsenu) .
• Ʋusɔgbɔdɔ (ʋusɔgbɔdɔ) .
• Dzi ƒe tsotso kabakaba (tachycardia) .
• Ʋuʋudedi
• Dɔmetɔtrɔ
• Sukli ƒe agbɔsɔsɔ si le ʋu me (suklidɔ ƒe agbɔsɔsɔ si medea ame dzi o) .

Ne dzesi siawo dometɔ aɖe le ŋuwò alo viwòa ŋu la, yi kɔdzi si te ɖe ŋuwò enumake alo nàƒo ka na 1990. Esia nye nudzɔdzɔ kpata!

Nukae nye Panhypopituitarism ƒe dzesiwo?

Dɔléle sia ƒe dzesiwo ate ŋu ato vovo ŋutɔ tso ame ɖeka gbɔ yi bubu gbɔ, le alesi gbegbe lãmetsi ɖesiaɖe si le lãkusi me mebɔ o kple alesi dɔlélea le ŋgɔ yim kabakaba alo blewui nu.

Dzesi siwo bɔ siwo woate ŋu akpɔ le ɖeviwo kple ame tsitsiwo ŋu dometɔ aɖewoe nye esi:

• Ʋuʋudedi alo taɖuame
• Ðeɖiteameŋu si gbɔ eme
• Blanuiléle kple/alo dzimaɖitsitsi
• Dɔlékuiwo xɔxɔ enuenu
• Sukli ƒe agbɔsɔsɔ si le ʋu me (suklidɔ ƒe agbɔsɔsɔ si medea ame dzi o) .
• Ŋutete manɔamesi be wòado dzi le vuvɔa me
• Ŋutilã si ƒu le mɔ si mebɔ o nu
• Lolo dzi ɖeɖe kpɔtɔ alo dzidziɖedzi le susu aɖeke manɔmee
• Ʋumemi kple ʋumemi ƒe agbɔsɔsɔ si mesɔ o (dyslipidemia) .
• Dzi ƒe tsotso kabakaba (tachycardia) .
• Tsikɔwuame fũ kple aɖuɖɔtoe enuenu
• Dzinukpɔkpɔ si mebɔ o le nyɔnuwo me
• Nyɔnuwo ƒe vidzidzimakpɔmakpɔ
• Ŋutsuwo ƒe vidzidzimakpɔmakpɔ

Dzesi bubu aɖewo li siwo gblẽa nu le vidzĩ yeyewo, vidzĩwo, kple/alo ɖevi suewo koŋ ŋu:

• Jaundice si nɔa anyi didi le vidzĩ yeyewo ŋu
• Vidzinu sue aɖe le vidzĩ ŋutsuwo me (micropenis) .
• Tsitsi si tsi megbe (menye tsitsi kɔkɔ wu o) .
• Ƒewuiwo ƒe heheɖemegbe

Esi wònye be dzesi siawo ate ŋu asɔ kple atikewɔwɔ me nɔnɔme bubuwo ta la, ele vevie be woakpɔ dɔlélea nyuie ne dzesi yeyewo alo esiwo nɔa anyi ɖaa abe esiawo ene le ŋuwò. Eyata yi ɖɔkta gbɔ hena aɖaŋuɖoɖo.

Nukawoe hea panhypopituitarism vɛ?

Nu geɖe li siwo ate ŋu ahe nɔnɔme sia vɛ. Ɣeaɖewoɣi la, ɖɔktawo mete ŋu kpɔa nusi koŋ gbɔ wòtso o. Woyɔa esia be idiopathic panhypopituitarism.

Le nyateƒe me la, nusi koŋ gbɔ esia tsoe nye be míaƒe hypothalamus kple/alo pituitary gland gblẽ le mɔ aɖe nu, si na wo dometɔ ɖeka alo evea siaa mewɔa dɔ nyuie o.

Be nàse susu siawo gɔme la, ele be nàse alesi míaƒe hypothalamus kple pituitary gland wɔa dɔ ɖekae gɔme vie.

Hypothalamus kple pituitary gland dome ƒomedodo

Bu míaƒe hypothalamus, pituitary gland, kple pituitary gland ŋu kpɔ abe dɔwɔƒe gã aɖe ƒe dɔdzikpɔlagã kple dɔdzikpɔla ene. Ne ame eve siawo ƒo ƒu wɔa dɔ abe míaƒe ahɔhɔ̃a dzikpɔƒe vevitɔ (hypothalamus-pituitary complex), eye wokpɔa dɔwɔwɔ vevi ŋutɔ siwo le ŋutilãa me dzi.

Hypothalamus nye míaƒe ahɔhɔ̃ ƒe akpa si kpɔa ŋutilãa ƒe dɔ vevi geɖe dzi. Eɖoa gbedasiwo ɖe míaƒe lãmeka siwo le wo ɖokui si. Egblɔna na pituitary gland hã be "wòawɔ lãmetsi siawo, aɖe asi le esiawo ŋu." Pituitary hormone siawo kpɔa ŋusẽ ɖe ŋutilã ƒe akpa bubuwo dzi.

Pituitary gland do ƒome kple hypothalamus to atikutsetse si me ʋukawo kple lãmekawo le si woyɔna be ``pituitary stalk.'' To atikutsetse sia dzie hypothalamus doa ka kple pituitary gland.

Hypothalamus wɔa lãmetsiŋusẽ geɖe tsɔ doa ŋusẽ pituitary gland:

• Lãmetsi si ɖea corticotropin ɖa
• Dopamine ƒe atike
• Lãmetsi si ɖea gonadotropin ɖa
• Lãmetsi si ɖea tsitsi ƒe lãmetsiwo ɖa
• Somatostatin ƒe atike
• Lãmetsi si ɖea thyrotropin ɖa

Esi wònye be pituitary gland kple hypothalamus wɔa dɔ ɖekae ta la, nusiwo gblẽ le ɖeka ŋu ate ŋu akpɔ ŋusẽ ɖe evelia ƒe lãmetsiŋusẽ ƒe dɔwɔwɔ dzi. Esiae nye nu vevitɔ si gbɔ panhypopituitarism ƒe dɔlélea tso.

Nusiwo do ƒome kple pituitary gland

Nɔnɔme siwo ate ŋu agblẽ nu le ʋuka si me ʋu sina tona ŋu eye wòahe panhypopituitarism vɛ dometɔ aɖewoe nye:

• Pituitary adenomas (esiawo nye dɔdzẽ siwo menye kansa o) .
• Pituitary gland ƒe dɔwɔwɔ (zi geɖe be woaɖe adenomas siawo ɖa) .
• Kekeli ƒe atikewɔwɔ na pituitary adenoma
• Pituitary apoplexy (pituitary tissue ƒe tsɔtsrɔ̃ kpata le ʋu ƒe sisi yi pituitary gland alo ʋu ƒe dodo ta) .
• Pituitary gland metsi nyuie o alo edzɔna le mɔ si mesɔ o nu le vidzidzi me.

Nusiwo gbɔ wòtsona siwo do ƒome kple hypothalamus

Nɔnɔme siwo ate ŋu agblẽ nu le hypothalamus ŋu eye wòahe panhypopituitarism vɛ dometɔ aɖewoe nye:

• Ahɔhɔ̃ ƒe abi si nu sẽ (TBI) .
• Ahɔhɔ̃mekoko si wowɔna le hypothalamus alo teƒe si te ɖe eŋu
• Dɔdzẽ siwo menye kansa o siwo dona le hypothalamus me (e.g. craniopharyngiomas) .
• Kansa si kaka (si kaka) yi hypothalamus tso ŋutilã ƒe akpa bubuwo (e.g. lãkusi, no me dɔdzẽ) .
• Hydrocephalus (nyaƒoɖeamenu si tso tsi ƒe ƒoƒo ɖe ahɔhɔ̃a me gbɔ) .
• Gbagbãdᴐ
• Yɔmekpe ƒe taɖuame

Aleke wowɔa dea dzesi Panhypopituitarism ƒe dɔlélea?

Ne dɔléle sia ƒe dzesiwo le ŋuwò la, wò ɖɔkta abia wò gbã tso wò dzesiwo kple wò atikewɔwɔ ŋutinya ŋu, eye emegbe wòado wò ŋutilã kpɔ.

Emegbe woɖea gbe be woawɔ dodokpɔ siwo hiã be woatsɔ aɖo kpe panhypopituitarism ƒe nɔnɔmea dzi eye woaɖe nɔnɔme bubu siwo ate ŋu ahe dzesi siawo vɛ la ɖa.

Nukawoe nye dodokpɔ siwo wowɔna tsɔ dia dɔlélea?

Zi geɖe la, ɖɔktawo wɔa dodokpɔ geɖe tsɔ dea dzesi dɔléle sia, siwo dometɔ aɖewoe nye nɔnɔmetatawo dodokpɔ kple lãmetsiŋusẽ ƒe agbɔsɔsɔ dodokpɔ.

Nɔnɔmetatawo ɖeɖe ƒe dodokpɔwo

Panhypopituitarism tsoa nusiwo gblẽ le hypothalamus alo pituitary gland ŋu gbɔ, eye woate ŋu awɔ nɔnɔmetata dodokpɔwo abe esiawo ene atsɔ adi nusi gbɔ wòtso:

• Brain MRI (Magnetic Resonance Imaging) scan: MRI scan zãa radio ƒutsotsoewo kple magnet-ŋusẽ sesẽ aɖe tsɔ wɔa ŋutilãa ƒe akpa si le eme ƒe nɔnɔmetata tsitotsito. Wobua MRI-dɔdamɔnu be enye mɔ nyuitɔ si dzi woato ake ɖe dɔdzẽ siwo le lãkusi me ŋu. Woate ŋu akpe ɖe ame ŋu hã be woanya kuxi bubu siwo le hypothalamus alo pituitary gland ŋu.
• CT (Computed Tomography) scan of the brain: CT scan zãa X-ray kple kɔmpiuta tsɔ wɔa ahɔhɔ̃a ƒe nɔnɔmetata tsitotsito. Woate ŋu azã dodokpɔ sia atsɔ akpɔe ɖa be ahɔhɔ̃ me dɔdzẽ alo pituitary adenoma le eŋu hã. Ate ŋu akpe ɖe ame ŋu hã be woanya kuxi bubu siwo le hypothalamus alo pituitary gland ŋu.

Lãmetsiŋusẽ dodokpɔwo

Ne panhypopituitarism ƒe dzesiwo le ŋuwò la, ahiã be wò ɖɔkta nadzidze lãmetsi ɖesiaɖe si pituitary gland ɖena ɖe go ƒe agbɔsɔsɔ. Esia akpe ɖe ŋuwò nànya alesi gbegbe lãmetsi ɖesiaɖe le sue eye wòaɖe nɔnɔme bubuwo ɖa.

Togbɔ be zi geɖe la, lãmetsi aɖewo nɔa míaƒe ʋu me le agbɔsɔsɔ si nɔa anyi ɖaa me hã la, lãmetsi bubuwo ƒe agbɔsɔsɔ ya nɔa tɔtrɔm ŋutɔ le ŋkekea me. Eyata woate ŋu awɔ lãmetsiŋusẽ dodokpɔ aɖewo abe ʋudodokpɔ bɔbɔewo ene, evɔ bubuwo ya hiã be woawɔ dodokpɔ tɔxɛ siwo doa ŋusẽ ame.

Lãmetsiŋusẽ ƒe agbɔsɔsɔme dodokpɔwo dometɔ aɖewoe nye:

• Ʋudodokpɔ: Ʋudodokpɔ bɔbɔewo ate ŋu adzidze lãmetsi siwo le lãkusi me abe lãmetsi si doa ŋusẽ ʋumenugbagbeviɣidɔ (TSH), prolactin, lãmetsi si doa ŋusẽ lãkusi (FSH), kple lãmetsi si naa ʋumenugbagbeviɣidɔ (LH). Woate ŋu adzidze lãmetsiŋusẽ bubu siwo dzi lãmetsi siwo le lãkusi me, abe thyroxine, estrogen, kple testosterone ene, kpɔ ŋusẽ ɖo hã.
• ACTH ƒe dzodzo dodokpɔ:Esia doa alesi wò adrenal glandwo wɔa nu ɖe ​​adrenocorticotropic hormone (ACTH) ŋui kpɔna. Esia bia be woado ACTH si wowɔ na wò eye woaɖe ʋu le ɣeyiɣi aɖewo me.
• Tsitsi ƒe lãmetsi (GH) ƒe dzodzo dodokpɔ: Le dodokpɔ sia gome la, wò ɖɔkta ado atike aɖe wò. Zi geɖe la, atike sia ʋãa ʋuka si me ʋu sina tona be wòaɖe tsitsi ƒe lãmetsiŋusẽ ɖe go. Emegbe, woaɖe wò ʋu eye woadzidze wò GH ƒe agbɔsɔsɔ.
• Insulin ƒe mɔɖeɖe ɖe nu ŋu dodokpɔ: Dodokpɔ sia kpena ɖe ame ŋu wòdea dzesi tsitsi ƒe lãmetsi (GH) kple ACTH ƒe anyimanɔmanɔ.

Aleke wodaa Panhypopituitarism ƒe dɔléleae?

Dɔléle sia ƒe atikewɔwɔ toa vovo tso ame ɖeka gbɔ yi bubu gbɔ. Enɔ te ɖe alesi lãmetsi si le lãkusi me ƒe agbɔsɔsɔ le sue kple nusi gbɔ wòtso dzi. Eyata atikewɔwɔ ƒe ɖoɖoa nye ame ɖekaɖeka tɔ ŋutɔ. Wò atikewɔlawo ƒe ƒuƒoƒoa atso nya me le atikewɔwɔ ƒe ɖoɖo nyuitɔ kekeake ŋu na wò.

Atikewɔwɔmɔnu siwo wozãna zi geɖe dometɔ aɖewoe nye:

• Lãmetsiŋusẽ ɖɔliɖɔli ƒe atikewɔwɔ: Esia ƒe taɖodzinue nye be woagbugbɔ lãmetsi siwo le lãkusi me siwo vɔ le lãme na ame la aɖo nɔƒe si sɔ. Ame siwo ŋu panhypopituitarism le la ahiã atikewɔwɔ si woatsɔ aɖɔli lãmetsiŋusẽ le woƒe agbemeŋkekewo katã me negbe ɖe woate ŋu ada nusi gbɔ wòtso hafi. Wonoa lãmetsiŋusẽtike aɖewo abe atikekui ene, eye wodoa bubuwo abe atikekui ene.
• Amekoko: Ne ahɔhɔ̃ me dɔdzẽ alo pituitary adenoma gbɔe dɔlélea tso la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ dɔ nɛ atsɔ aɖe dɔdzẽa ɖa.
• Kekelidɔdada: Ne ahɔhɔ̃meka alo pituitary adenoma gbɔe dɔlélea tso la, woate ŋu akafu keklẽŋusẽdɔdamɔnu be woatsɔ ada dɔdzẽa alo aɖe edzi akpɔtɔ.
• Corticosteroids: Ðewohĩ ahiã be nàno corticosteroids ƒe agbɔsɔsɔ gã aɖe do ŋgɔ na nudzɔdzɔ ɖesiaɖe si ahe ŋutilã alo susu me nuteɖeamedzi vɛ kple/alo le ewɔɣi. Nuteɖeamedzi siwo tsoa ŋutilã me dometɔ aɖewoe nye dɔléle, dɔlékuiwo xɔxɔ, kple amekoko. Wonaa corticosteroid siawo be woatsɔ axɔ ɖe adrenal hormone siwo womewɔna le ACTH ƒe anyimanɔmanɔ ta o la teƒe. Lãmetsiŋusẽ siawo hiã vevie ne ŋutilãa le nuteɖeamedzi me.

Ðe woate ŋu ada Panhypopituitarism keŋkeŋa?

Le go aɖewo me la, woate ŋu atrɔ panhypopituitarism ne woda nusi gbɔ wòtso (le kpɔɖeŋu me, amekoko aɖe pituitary adenoma si nɔ tetem ɖe pituitary gland ŋu, ne gland la megblẽ o). Gake le go geɖe me la , lãmetsiŋusẽ ƒe gbɔdzɔgbɔdzɔ si panhypopituitarism hena vɛ la hiã be woawɔ atike na wo le woƒe agbemeŋkekewo katã me.

Ðe woate ŋu axe mɔ ɖe nɔnɔme sia nua?

Zi geɖe la, mɔ aɖeke meli si dzi woato axe mɔ ɖe panhypopituitarism nu o. Gake ne èle afɔku me be nàxɔ nɔnɔme sia la, mɔ aɖewo li siwo dzi nàto ade dzesii kaba.

Ne èto nusiwo gbɔna dometɔ aɖe me la, ke afɔku le eme be nàxɔ panhypopituitarism:

• Ne wowɔ dɔ na wò le ahɔhɔ̃ alo pituitary gland ŋu kpɔ.
• Ne wotsɔ keklẽŋusẽ da dɔ na wò kpɔ na ahɔhɔ̃a kple/alo lãkusi si me ʋu sina tona.
• Ne ahɔhɔ̃a kpe fu le afɔku aɖe ta (Traumatic brain injury).
• Ne hydrocephalus (tsi si ƒoa ƒu ɖe ahɔhɔ̃a dzi) le fu ɖem na wò.

Ne èle afɔku me la, wò ɖɔkta aɖo aɖaŋu zi geɖe be nàlé ŋku ɖe wò lãkusi kple/alo hypothalamus ƒe dɔwɔwɔ kple lãmesẽ ŋu.

Nukae nye panhypopituitarism ƒe ŋgɔdonya?

Mɔkpɔkpɔ na dɔléle sia, si nye alesi dɔnɔa anɔ le etsɔme, nɔ te ɖe nu geɖe dzi:

• Aleke gbegbee pituitary hormone ɖesiaɖe le sue.
• Ƒe si nèxɔ esime dɔlélea dze egɔme.
• Ðe nɔnɔme sia ava do vivivi loo alo kaba?
• Aleke woate ŋu ade dzesi dɔlélea kaba eye woadze edada gɔme?

Wokpɔe be panhypopituitarism do ƒome kple agbenɔnɔ ƒe nyonyome kple agbenɔƒe dzi ɖeɖe kpɔtɔ ŋutɔ.

Zi geɖe la, amesiwo ŋu dɔléle sia le la ƒe lolo akpa, woƒe ŋutilã ƒe lolome dzi ɖena kpɔtɔna, eye dzitodzito me dɔlélewo dzina ɖe edzi. Ate ŋu adzɔ hã be ƒumeŋuɖui (ƒuwo ƒe ƒuƒu) kple ƒu ƒe gbagbã ƒe afɔku nadzi ɖe edzi.

Gake lãmetsiŋusẽ ɖɔliɖɔli ƒe atikewɔwɔ nyuie, bliboe kple ŋkuléle ɖe dzitodzito ƒe afɔkuwo ŋu nyuie ate ŋu ana emetsonuwo nanyo ɖe edzi. Eyata ele vevie ŋutɔ be nàwɔ ɖe atikewɔlawo ƒe aɖaŋuɖoɖowo dzi.

Ɣekaɣie wòle be nàkpɔ ɖɔkta ne panhypopituitarism le ŋuwò?

Ne panhypopituitarism ƒe dzesiwo le ŋuwò, alo wokpɔ dɔlélea le ŋuwò la, anɔ eme be ahiã be nàkpɔ lãmenugbagbeviwo ŋuti nunyala, si nye ɖɔkta si bi ɖe lãmetsiŋusẽ ƒe dɔlélewo dada me.

Ahiã be nàyi wò lãmenugbagbeviwo ƒe dɔwɔwɔ ŋuti nunyala gbɔ edziedzi le wò agbemeŋkekewo katã me be nàkpɔ egbɔ be wò lãmetsiŋusẽtikea le dɔ wɔm nyuie eye be nàƒo asa na lãmetsiŋusẽtikewo ɖɔliɖɔli fũ akpa.

Enye nusi sɔ be vɔvɔ̃ naɖo ŋuwò ne wokpɔ dɔléle yeye aɖe le ŋuwò. Gake mègavɔ̃ be yeabia nya wò ɖɔkta tso panhypopituitarism ŋu o. Esi wònye zi geɖe la, ebia be woawɔ atike nɛ le wò agbemeŋkekewo katã me eye woalé ŋku ɖe lãmetsiŋusẽ ƒe dɔwɔwɔ ŋu ta la, ele vevie be nàyi ɖɔkta gbɔ edziedzi. Ne dzesi yeyewo alo dzimaɖitsitsi dze ŋuwò la, na wò ɖɔkta nanya enumake. Wole afima be yewoakpe ɖe ŋuwò.

Nu vevi siwo dzi wòle be woaɖo ŋkui (Take-Home Message) .

Enyo, eyata mina míaƒo nu tso nusiwo dzi wòle be nàɖo ŋkui tso nusiwo ŋu míeƒo nu tsoe me la dometɔ aɖewo ŋu kpuie:

• Panhypopituitarism nye dɔléle si mebɔ o gake wòsẽa ŋu ŋutɔ si me lãmetsiŋusẽ siwo katã ƒumeŋuɖui wɔna dzi ɖena kpɔtɔna.
• Susu geɖe ate ŋu anɔ esia ŋu, vevietɔ nusiwo gblẽ le pituitary gland alo hypothalamus ŋu.
• Dzesiawo toa vovo, eye ɣeaɖewoɣi la, nɔnɔme siwo ate ŋu ade ame ƒe agbe afɔku me abe adrenal crisis ene gɔ̃ hã ate ŋu ado mo ɖa. Eya ta, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake ne dzesiwo le ŋuwò.
• Nuwo abe ʋudodokpɔ kple MRI/CT-dɔdamɔnu ene hiã hafi woate ŋu anya dɔlélea nyuie.
• Zi geɖe la, atikewɔwɔ bia be woazã lãmetsiŋusẽtikewo ɖɔliɖɔli le woƒe agbemeŋkekewo katã me.
• Ne èwɔ dɔ kplikplikpli kple wò ɖɔkta eye nèwɔ dodokpɔ kple atike siwo sɔ la, àte ŋu anɔ agbe kple nɔnɔme sia dzidzedzetɔe.

Mele mɔ kpɔm be nyatakaka sia akpe ɖe ŋuwò. Ðo ŋku edzi be menye wò ɖeka koe o, eye ɖɔktawo kple lãmesẽdɔwɔlawo le afima be yewoakpe ɖe ŋuwò.

` Panhypopituitarism, pituitary gland, lãmetsiŋusẽ ƒe anyimanɔmanɔ, hypothalamus, lãmetsiŋusẽ ƒe atikewɔwɔ, ahɔhɔ̃ me dɔdzẽ, ACTH