Mina míasrɔ̃ nu tso nɔnɔme sia si wotsɔ ŋkɔ wɔnuku aɖe si woyɔna be POEMS Syndrome ŋu.

Ne èse ŋkɔ sia la, ɖewohĩ Hakpanyawoe vaa susu me na wò, alo? Gake menye ŋutinya si ku ɖe hakpanyawo ŋue nye esia o. POEMS syndrome nye ʋudɔ si mebɔ kura o si ate ŋu agblẽ nu le míaƒe ŋutilã ƒe lãmekawo, ŋutinu vovovowo, lãmetsiŋusẽ ƒe dɔwɔwɔ, kple ŋutigbalẽ ŋu le ɣeyiɣi ɖeka me. Esesẽ vie be woakpɔe, elabena dzesi siwo do ƒome kplii ate ŋu asɔ kple dɔléle bubu geɖewo ƒe dzesiwo. Esia tae wòle vevie ŋutɔ be míanɔ ŋudzɔ ɖe esia ŋu ɖo.

Nukatae woyɔa esia be HAKPEKPEWO?

Exɔ ŋkɔ tso dɔlélea ƒe dzesi kple dzesi vevi atɔ̃ ƒe ŋɔŋlɔdzesi gbãtɔwo me. Na míakpɔ nusiwo wonye ɖa.

Ɣeaɖewoɣi la, exɔa dodokpɔ ɣleti geɖe hafi woate ŋu anya dɔléle sia, elabena woate ŋu atɔtɔ dzesi siawo kple dɔléle bubu geɖewo bɔbɔe ne wozã wo ɖe vovo.

Nukae nye POEMS ƒe dɔlélea ƒe dzesiwo?

Azɔ mina míalé ŋku ɖe HAKPƆKPƆ siwo ŋu míeƒo nu tsoe le etame ƒe akpa ɖesiaɖe ƒe dzesiwo ŋu tsitotsito.

• P - Lãmetsiŋusẽ ƒe gbegblẽ (Polyneuropathy): Esiae nye nu gbãtɔ si ame geɖe dea dzesii. Afɔbidɛwo kple afɔbidɛwo ate ŋu ase le wo ɖokui me be yewole ʋuʋum, wole ƒoƒom, eye woate ŋu ase dzobibi alo vevesese sesẽ . Le ɣeyiɣi aɖe megbe la, nɔnɔme sia ate ŋu akaka ɖe asiwo me. Ŋusẽ si le asiwo me dzi ɖena kpɔtɔna, eye ɖewohĩ màte ŋu alé naneke ɖe asi o. Le nɔnɔme sesẽwo me la, ate ŋu asesẽ be woatsi tre, azɔ azɔli, eye woagbɔ ya gɔ̃ hã.

• O - Organomegaly: Wò aklã, dɔgbo, alo ʋukawo ate ŋu avuvu. Esia ate ŋu ahe dzesiwo abe alesi woase le wo ɖokui me be yeƒe lãme yɔ fũ, ƒodo ƒe veve alo fuɖename, kple ɖeɖiteameŋu si gbɔ eme ene vɛ .

• E - Lãmetsiŋusẽ ƒe tɔtrɔ (Endocrinopathy): Lãmetsiŋusẽ ƒe tɔtrɔ ate ŋu ahe nuwo abe gbɔdɔdɔ ƒe dzodzro dzi ɖeɖe kpɔtɔ, notsi ƒe dodo tso no me (na nyɔnuwo kple ŋutsuwo siaa), kple asiwo kple afɔwo ƒe vuvu .

• M - M-protein si mesɔ o: Protein sia ate ŋu aƒo ƒu ɖe ʋu me eye wòana ƒuwo nagbɔdzɔ alo agblẽ , si ate ŋu ana ƒuwo nase veve.

• S - Ŋutilã ƒe tɔtrɔ: Ŋutilã ate ŋu ado viviti wu alesi wòle dzɔdzɔmee. Ɣeaɖewoɣi la, ŋutigbalẽa ate ŋu aƒo, eye teƒe dzĩwo ate ŋu adze le akɔta. Taɖa ate ŋu adzi ɖe edzi le mo kple afɔwo hã, eye ɖaawo ate ŋu azu ɣie .

Nukatae nane si le abe esia ene dzɔna?

Womenya nusi tututu gbɔ esia tso haɖe o, gake ɖɔktawo kple numekulawo xɔe se be edo ƒome kple lãmenugbagbevi ƒomevi aɖe si le míaƒe ŋutilã me si woyɔna be plasma cells ƒe dɔwɔwɔ le mɔ si mesɔ o nu .

Kpuie ko la, ʋumenugbagbevi dzĩ siawo siwo mesɔ o la ɖea M-protein si ŋu míeƒo nu tsoe la ɖe ʋua me. Lãmenugbagbevi siawo siwo mesɔ o kple M-protein la ƒoa ƒu gblẽa nu le ŋutilã ƒe akpa vovovowo ŋu. Tsɔ kpe ɖe eŋu la, protein aɖe si woyɔna be Vascular Endothelial Growth Factor (VEGF) hã sɔ gbɔ ɖe dɔnɔ siawo ƒe ʋu me. VEGF protein sia nana tsi sina tso ʋukawo me yia lãkusi siwo ƒo xlãe me. Lãmetsi sia si sɔ gbɔ wu la nana wòvuvu, ŋutinuwo lolona, ​​eye wògblẽa nu le lãmekawo ŋu.

Ðe nɔnɔme sia ate ŋu anye nu sesẽa?

Ẽ, ɣeaɖewoɣi la, POEMS ƒe dɔlélea ate ŋu asẽ kabakaba, si ahe kuxi siwo ate ŋu ade ame ƒe agbe afɔku me vɛ.

Wo dometɔ aɖewoe nye:

• Capillary Leak Syndrome: Ŋutinuwo ƒe dɔmawɔmawɔ nyuie ate ŋu adzɔ le tsi si le dodom fũu akpa tso ʋukawo me ta.
• Aklãdɔléle si xea mɔ na ame: Yagbɔgbɔ sesẽ le esi lãkusiwo mete ŋu kekena nyuie o ta.
• Aklã me Ʋusɔgbɔdɔ: Ʋuka siwo tsɔa ʋu yia aklã me ƒe nyaƒoɖeamenu fũu akpa.

Aleke ɖɔkta awɔ ake ɖe esia ŋu?

Ne èyi ɖɔkta gbɔ la, aɖo to wò dzesiwo nyuie. Emegbe ado wò ŋutilã kpɔ eye wòaɖo aɖaŋu be nàwɔ dodokpɔ geɖe atsɔ aɖo kpe dɔlélea dzi.

Tsɔ kpe ɖe eŋu la, woate ŋu awɔ gbɔgbɔmedodokpɔwo, echocardiograms, kple lãmetsiŋusẽ dodokpɔwo le wò dzesiwo nu.

Nukawoe nye atike siwo wozãna na esia?

Taɖodzinu vevitɔ si le atikewɔwɔ ŋue nye be woaɖu dzesiwo kple ʋumenugbagbevi dzĩ siwo mesɔ o dzi. Atike vovovowo li na esia.

• Atikewɔmɔnu: Atikewɔwɔ sia gblẽa ʋumenugbagbevi dzĩ siwo mesɔ o alo wodzudzɔa woƒe tsitsi.
• Dɔlélenutsiŋutete ƒe dɔdamɔnu: Atike siawo kpena ɖe ŋuwò nèzãa wò ŋutɔ wò dɔlélenutsiŋutete tsɔ tsrɔ̃a ʋumenugbagbevi dzĩ siwo mesɔ o.
• Kekeli ƒe dɔdamɔnu: Kekeli ƒe dɔdamɔnu gblẽa ʋumenugbagbevi dzĩ siwo mesɔ o.
• Autologous stem cell transplant: Esia bia be woaɖe ʋumenugbagbevi dzĩ siwo mesɔ o ɖa le wò ŋutilã me eye nàtsɔ lãmenugbagbevi siwo le lãmesẽ me aɖo wo teƒe.
• Lãmesẽnyawo gbɔ kpɔkpɔ: Lãmetsiŋusẽ ƒe gbegblẽ ate ŋu ana azɔlizɔzɔ kple gbesiagbedɔwo wɔwɔ nasesẽ. Lãmesẽfefewo ate ŋu akpe ɖe ŋuwò be ŋusẽ nagaɖo ŋuwò.
• Susuŋutinunya ƒe kpekpeɖeŋu: Agbenɔnɔ kple dɔléle si mebɔ o, si womate ŋu ada o abe esia ene ate ŋu asesẽ ŋutɔ le susu me. Esia ate ŋu ahe nɔnɔmewo abe dzimaɖitsitsi kple blanuiléle ene vɛ. Aɖaŋuɖola ƒe kpekpeɖeŋu didi ate ŋu akpe ɖe ŋuwò nàɖu nuteɖeamedzi sia dzi.

Ɣeyiɣi didi kae nàte ŋu anɔ agbe kple dɔléle sia?

Esia nye kuxi si le ame geɖe ŋu. Ne wokpɔ dɔlélea dze sii kaba eye wodae nyuie la, ame geɖe ate ŋu anɔ agbe ƒe 10 alo esi wu nenema le dɔlélea kpɔkpɔ vɔ megbe. Atike yeyewo va li fifia be woatsɔ ada dɔléle sia. Ke hã, esia ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ. Ame nyuitɔ si ana numeɖeɖe kple gɔmesese nyuitɔ nasu asiwò le wò nɔnɔmea ŋue nye wò ɖɔkta. Eyata ƒo nu kplii gaglãa tso eŋu.