When your doctor prescribes Alectinib to you or someone you know, it's normal to have a lot of questions about it. "Will it help?", "What side effects will it cause?", "How should I use it?", etc. Don't worry, today we'll talk about this medication in a simple and clear way. This information will be a great strength and help to you on this journey.
What exactly is Alectinib?
Simply put, Alectinib is a special drug that stops the growth of cancer cells. This is not like the usual chemotherapy drugs that we have all heard of. This belongs to a type of treatment called 'targeted therapy'.
This means that the drug is designed to target specific proteins in cancer cells and attack them only. This means that it causes relatively little damage to healthy cells. Alectinib is mainly used to treat non-small cell lung cancer (NSCLC) .
Things you need to tell your doctor before starting medication
Before starting this medication with your doctor, it is very important to give a complete and honest account of your health condition, without hiding anything. Because that information will be used to decide whether this medication is suitable for you or not. Be sure to tell them about the following in particular:
- If you have had or currently have heart disease .
- If you have had times when your heartbeat was irregular .
- If you have any liver disease.
- If you have lung or breathing problems, such as asthma.
- If you have muscle pain or weakness .
- If you have allergies to this medicine, Alectinib, or any other medicine, food, or dye.
- If you are pregnant, trying to get pregnant, or breastfeeding .
By telling you these things accurately, your doctor can plan the safest treatment for you.
How exactly should I use this medicine?
To get the most out of a medication, it is essential to use it correctly.
- Take this capsule by mouth with a glass of water.
- The most important thing is that this medicine should always be taken with a meal. Do not take it on an empty stomach.
- Do not break, crush, or chew the capsule. Swallow it whole.
- Usually, your doctor will tell you to take this every 12 hours (for example, 8 am and 8 pm). Try to keep to that time exactly.
- If you vomit after taking the medicine, do not take another dose. Take the next dose at your usual time.
- If you miss a dose, do not take a double dose as soon as you remember. Skip the missed dose and take the next dose at the scheduled time.
- Never stop taking medication without your doctor's advice.
What if I overdose?
If you have any suspicion that you have taken more medicine than you think, immediately call the National Poisons Information Centre at the Colombo National Hospital, or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
Special points to be aware of when taking the medicine
There are several things to consider regarding your safety while taking this medication.
Be careful of the sun!
This medicine may make your skin very sensitive to the sun. This means that your skin may burn and turn red very quickly.
- Avoid exposure to strong sunlight during the day as much as possible.
- If you go outside, cover your skin with long-sleeved clothing, pants, and a hat.
- Use a good sunscreen with SPF 50 or higher and a lip balm. Continue doing this for a week after stopping the medication.
- Avoid exposure to artificial sunlight, such as tanning beds, completely.
Avoid pregnancy (for women and men)
This medicine can cause serious harm to the unborn baby.
- Women: You should avoid becoming pregnant while taking the medicine and for one week after the last dose. If you have any suspicion that you are pregnant, tell your doctor immediately.
- Men: You must use a highly effective form of birth control to prevent your partner from becoming pregnant while taking the medicine and for 3 months after the last dose.
Other things to consider
- Blood tests: When your doctor prescribes this medication, he or she will order regular blood tests to monitor things like your liver and kidney function. Don't skip these tests.
- Painkillers: Do not take painkillers like aspirin or ibuprofen without your doctor's advice. These can help reduce fever, but it's important to know that fever can be a sign of an infection.
- Protect yourself from infections: This medicine may slightly reduce the body's ability to fight diseases. Therefore, stay away from people with colds and fevers. If you have a fever, chills, or a sore throat, do not self-medicate and tell your doctor.
- Unusual bleeding: If you experience any unexplained bruising or if bleeding does not stop even from a minor injury, tell your doctor immediately.
What side effects might I experience?
Like any medicine, Alectinib can cause side effects. But not everyone gets them. Only some people get them. Let's break these down into two categories.
| Type of side effect | Expected features |
|---|---|
| Serious side effects that require immediate reporting to the doctor or going to the ETU | |
| Allergic Reactions | Skin rash, itching, swelling of the face, lips, tongue. |
| Difficulty breathing | Sudden shortness of breath, chest pain. |
| Symptoms of liver damage | Dark yellow or brown urine, loss of appetite, pain in the upper right side of the stomach, yellowing of the eyes or skin. |
| Symptoms of kidney damage | Difficulty urinating or a change in the amount of urine you pass. |
| Muscle damage | Dark urine, unusual weakness, severe muscle pain. |
| Dizziness/Dizziness | Dizziness , blue eyes, and fainting. |
| Common side effects that should be reported to your doctor if they persist or are bothersome: | |
| Digestive system problems | Constipation, diarrhea, vomiting. |
| Other | Headache, swelling of ankles, hands, feet. |
Take-Home Message
- Always take Alectinib with a meal . Do not take it on an empty stomach.
- Never stop taking your medication without your doctor's advice.
- It is essential to protect yourself from the sun while taking the medication. Use an SPF 50+ sunscreen.
- Avoid pregnancy completely while taking the medication and for as long as your doctor tells you. This applies to both women and men.
- If you experience any serious symptoms such as difficulty breathing, yellowing of the eyes, or severe muscle pain, call your doctor immediately or go to the nearest hospital's Emergency Department (ETU).
- Be sure to attend all blood tests and clinic visits prescribed by your doctor.


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