Have you ever had severe bladder pain or frequent spasms? Sometimes, it's hard to control this pain with regular painkillers. In such cases, if other painkillers don't work for you, today we're going to talk about a special medicine that your doctor can prescribe. This is a rectal suppository.
What is this medicine? How does it work?
Simply put, it's a combination of two drugs. Belladonna and Opium . These two work together to reduce your pain.
1. Belladonna: This is a type of medicine called an antispasmodic . It works by relaxing the muscles in your bladder and reducing the spasms. It's like gently relaxing a tight muscle.
2. Opium: This is a powerful painkiller called an opioid . It works by blocking pain signals from reaching your brain. This greatly reduces the pain you feel.
Because both of these methods work together, this medicine can control the severe pain caused by bladder spasms.
Things you need to tell your doctor before taking medicine
Before using this medicine, it is very important to give your doctor a complete description of your health condition. Especially if you have any of the following conditions, be sure to tell them about it.
| Conditions to report to your doctor | |
|---|---|
| • Brain tumor | • Frequent drinking |
| • Glaucoma | • Head injury |
| • Heart disease | • High blood pressure |
| • Kidney or liver disease | • Lung disease, asthma, or breathing difficulties |
| • Decreased adrenal function | • Myasthenia Gravis |
| • Prostate disease | • Seizures |
| • Stomach or intestinal problems | • A history of drug addiction |
| • If you have taken an MAOI medication (e.g. Parnate) in the past 14 days | • Allergic reaction to belladonna, opium or other medicines, foods, or dyes |
| • If you are pregnant or trying to get pregnant | • If you are a breastfeeding mother |
How exactly do I use this medicine?
This is a medicine for rectal use only. Do not take it orally for any reason. The way it is used is a little different, but don't worry, it's very easy. Let's see how to do it exactly.
1. Cleanliness: Wash your hands thoroughly with soap before and after using the medicine.
2. Preparation: Carefully remove the foil wrapping from the suppository. Lightly moisten the tip of the suppository with cold tap water. This will make insertion easier.
3. Position: Lie on your back. Keep the bottom leg straight and the top leg bent at the knee and pulled towards your stomach. It's like sleeping with a ball.
4. Insertion: Lift the buttock slightly to expose the rectum. Now insert the medicine stick all the way into the rectum, with the pointed end going first.
5. Staying still: After inserting the medicine, press your buttocks together for a few seconds. Then, continue to lie in that position for about 15 minutes . This will prevent the medicine from coming back out.
Most importantly: Do not use this medicine in more quantity or more frequently than prescribed by your doctor.
What if I miss a dose of medication?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take a double dose.
What if I take too much medicine?
If you think you have taken more medicine than you think, immediately call the National Poisons Information Centre at the Colombo National Hospital, or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
Interactions with this medicine
When you take this medicine, it may interact with other things. Therefore, tell your doctor about all the medicines you take (including vitamins and herbal remedies). Be especially careful about the following:
- Alcohol: Taking this medication with alcohol is very dangerous. It can cause serious side effects such as drowsiness and difficulty breathing.
- Medicines for allergies, coughs, and colds (Antihistamines)
- Medication for anxiety or sleep
- Some medications for depression (e.g. amitriptyline, fluoxetine)
- Anticonvulsant medication (e.g. phenobarbital)
- General anesthetics used during surgery
- Muscle relaxants for surgery
- Other opioid painkillers or cough medicines
Things to keep in mind when using the medicine
- About pain: Tell your doctor if your pain doesn't go away, gets worse, or if you develop a new type of pain.
- Tolerance: When you take this medicine for a long time, your body may become accustomed to it. Then the dose you took before may not be enough to control your pain. This is normal, don't worry. Your doctor will adjust the dose as needed.
- Addiction and Tolerance: This does not mean that you are addicted to the medication. Addiction is the misuse of the medication without a medical reason. You are taking the medication because you are in pain, and it is a medical necessity. When you need to stop taking the medication, your doctor will gradually reduce the dose. Do not stop suddenly.
- Drowsiness and dizziness: This medicine may make you feel drowsy and dizzy. Therefore, avoid activities that require alertness, such as driving or operating machinery. Especially if you are elderly, take care when getting up from a sitting position and when getting up from a lying position.
- Constipation: This medicine may cause constipation. If you do not have a bowel movement after 3 days, tell your doctor.
- Dry mouth: You may experience a dry mouth. This can be controlled by chewing sugar-free gum and drinking plenty of water.
Side effects of the medicine
| If you have these symptoms, tell your doctor immediately . | |
|---|---|
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Central nervous system depression (CNS depression) | Slow or shallow breathing, difficulty breathing, feeling faint, excessive sleepiness, inability to wake up. |
| Decreased adrenal function | Nausea, vomiting, loss of appetite, unusual tiredness, dizziness. |
| Low blood pressure | Dizziness, blue eyes, feeling faint. |
| Side effects that are usually seen, but should be reported to the doctor if they persist | |
| • Blurry vision | • Constipation |
| • Dizziness | • Drowsiness |
| • Dry mouth | • Headache, nausea, vomiting |
How to protect and remove the medicine?
This is a powerful medicine, so keep it out of reach of children and pets. Keep it in a safe place where thieves can't get it, as it can be misused. Don't share the medicine you've been given with anyone else. Doing so is dangerous and illegal.
Store at room temperature (between 15-30 Celsius). Do not refrigerate. Discard expired medication.
When disposing of unused medication, ask your doctor if it's okay to throw it in the trash. If it's okay to do so, mix the medication with something like coffee grounds, soil, or used tea leaves, put it in a sealable bag or container, and throw it in the trash.
Take-Home Message
- Use this medicine rectally only. Take only the prescribed amount as directed by your doctor.
- Tell your doctor about all other medications you are taking and any medical conditions you have.
- Avoid drinking alcohol completely while taking this medicine.
- Avoid driving and performing tasks that require attention, as drowsiness may occur.
- This medicine is for you only. Never share it with others. Keep it away from children and pets.
- Seek immediate medical attention if you experience difficulty breathing, excessive drowsiness, or severe allergic symptoms.


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