Do you also feel sleepy all day long? Even after sleeping well at night, do you feel so sleepy that you can't do anything during the day? Or do you suddenly feel like you're falling over when you laugh or are surprised? These are very disturbing experiences. Today we are going to talk about a special medicine that is prescribed to treat such specific sleep disorders.
What is this medicine?
Simply put, this is a liquid medicine made by combining the ingredients Calcium, Magnesium, Potassium, and Sodium Oxybates. It may be available in the market under the name `(Xywav)`.
This is not a general insomnia medication. It mainly treats:
- Narcolepsy: This is a condition in which you fall asleep uncontrollably at any time of the day.
- Idiopathic Hypersomnia: This also occurs when you feel excessively sleepy during the day, despite sleeping for hours at night.
- Cataplexy: This is a very special condition. When you experience a strong emotion, such as laughing out loud, being surprised, or angry, your body's muscles suddenly lose power. Sometimes you may even bend your knees or fall to the ground.
This medication works by reducing your daytime sleepiness and helping you sleep better at night. It also reduces the number of times you experience cataplexy, a sudden loss of muscle tone.
Things you need to tell your doctor before starting medication
Before starting this medication, it is very important to give your doctor a complete description of your health condition. Be sure to tell them if you have any of the following conditions:
- If you have depression or other mental illnesses.
- If you have ever been addicted to alcohol or other drugs/medications in the past.
- If you are an alcoholic .
- If you have liver disease .
- If you have breathing problems in your lungs , for example, sleep apnea.
- If you have a very rare, hereditary condition like succinic semialdehyde dehydrogenase deficiency .
- If you have ever had suicidal thoughts or attempted suicide, or if someone in your family has done so.
- If you have an allergic reaction to this medicine (Oxybate) or any other medicine, food, or dye.
- If you are pregnant or trying to get pregnant .
- If you are a mother who is breastfeeding .
How exactly should I use this medicine?
This is an oral liquid. It is very important to take it exactly as prescribed by your doctor, at the right time.
- Accurate measurement: Use the special syringe or measuring cup that comes with this medicine to measure it. Do not use household teaspoons or soup spoons, as they may not give an accurate measurement.
- How to take: You should mix the dose of medicine with a little water and drink it. Your doctor will explain how to do this.
- When to take: It is important to take this on an empty stomach . That means at least two hours after eating.
- Schedule: Take the medicine at the scheduled time as prescribed by your doctor. Do not take more than the prescribed amount or stop taking it suddenly without medical advice.
This medication is usually prescribed to be taken twice a night. The first dose should be taken just before going to bed and sleeping. The second dose should be taken 2.5 to 4 hours after the first dose. It is a good idea to set an alarm for this.
Important: You will receive a special instruction leaflet ``(MedGuide)`` with this medicine. Read it carefully. If you have any questions, talk to your doctor.
What if the dosage of the medicine is increased? (Overdosage)
If you think you have taken too much of this medicine, call the National Poisons Information Centre at the Colombo National Hospital immediately . Or go to the Emergency Department (ETU) of the nearest hospital. Do not delay.
What if I miss a dose?
If you miss a dose, skip it. Do not take two doses at once to make up for it. Take the next dose at the scheduled time.
Other things that may interact with this medicine
This medicine may interact with some things, so be aware of this as well.
| Do not take these with anything. | |
|---|---|
| Alcohol | Breathing can become dangerously slow. |
| Other sleeping pills | Excessive drowsiness and other serious side effects may occur. |
| These may also react (inform the doctor) | |
| Antihistamines | Medicines for colds, coughs, and allergies |
| Some medications for depression | Ex: Amitriptyline, Fluoxetine, Sertraline |
| Some medications for epilepsy | Ex: Phenobarbital |
| Narcotics | Strong painkillers like tramadol and morphine |
| General anesthetics | Anesthetics for surgery |
This list is not complete, so tell your doctor about all medications, vitamins, and herbal products you are taking.
Be especially careful about these things when taking medication.
- Excessive sleepiness and dizziness: This medication can make you sleepy very quickly. So always take your first dose at bedtime . Avoid driving, operating machinery, or doing anything that requires alertness for at least 6 hours after taking the medication.
- Sleep Activities: This is very important. You may wake up from your sleep and do things without realizing it. For example , sleep-driving, cooking, talking on the phone, and sleepwalking . You may not remember any of this the next morning. This can be serious. If you find out that you have done something like this, call your doctor immediately.
- Behavioral and mood changes: If you notice any changes in your behavior, such as feeling increasingly depressed, having thoughts of harming yourself, becoming increasingly angry, or becoming agitated , tell your doctor right away. Tell your family to be aware of these changes as well.
- Alcohol: The effects of this medication can be severe when taken with alcohol. Therefore, avoid alcohol completely while taking the medication.
What side effects might I experience?
Like any medicine, this can cause side effects.
| Serious side effects that should be reported to your doctor immediately | |
|---|---|
| Allergic reactions | Skin rash, itching, swelling of the lips/tongue/face, difficulty breathing. |
| Central nervous system depression (CNS depression) | Slow or shallow breathing, extreme dizziness, loss of consciousness, difficulty staying awake. |
| Mood changes | Excessive anxiety, depression, suicidal thoughts, agitation. |
| Sleep apnea | Loud snoring during sleep, waking up gasping for breath. |
| Sleepwalking | Getting up from sleep and walking or engaging in other activities. |
| Side effects that should be reported to the doctor if they persist or are bothersome | |
| Bedwetting | |
| Dizziness, headache | |
| Loss of appetite, nausea, vomiting | |
How to store and dispose of medicine safely?
This is very important. This medicine can be abused, so special care must be taken with it.
- Storage: Keep in a safe place, well-closed , out of the reach of children and pets. Protect from theft. This medicine is for you only. Never share it with anyone else.
- Disposal: It is essential to properly dispose of unused and expired medicines. These can be fatal if they end up in the hands of others, especially children. Check with a government drug collection program for this. Alternatively, you can mix them with water and throw them away in the sink. Get the right advice from your doctor.
Take-Home Message
- This is a medication for specific sleep disorders that should be taken under the strict supervision of a doctor. Take the prescribed dose at the prescribed time.
- Avoid drinking alcohol completely while taking this medication, and avoid taking it with other sleep-inducing medications.
- Be very careful about excessive sleepiness and sleep-driving, sleep-walking, which may occur after taking the medication.
- If you notice any unusual changes in your mood or behavior (depression, anger), inform your doctor immediately.
- Store the medicine in a safe place out of the reach of children, and dispose of any leftover medicine properly.


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