Your doctor may have prescribed you a medication to "reduce some of the unnecessary water in your body." This type of medication may be given, especially if your blood pressure is a little high, or if your feet and hands are swollen due to a condition in your heart, kidneys, or liver. One such medication is Chlorothiazide. Let's talk about this simply and kindly today.
What kind of medicine is Chlorothiazide?
Simply put, this is a drug that belongs to a class of drugs called diuretics . We usually call these "water pills" or "diuretics." What this does is make you urinate a little more. Then the extra water and salt that has accumulated in the body is excreted with the urine.
This is mainly used for:
- Control high blood pressure .
- Reduce swelling in the body caused by heart disease, kidney disease, or liver disease.
This can be purchased under the brand name Diuril. But no matter what name your doctor prescribes, it will likely contain the same drug.
Things you need to tell your doctor before starting this medication
It is essential that your doctor knows your complete medical history before prescribing this medication. Therefore, be sure to tell your doctor if you have any of the following conditions:
- If you have a condition like dehydration .
- If you have diabetes or high blood sugar levels.
- If the levels of electrolytes in the blood, that is, salts such as sodium, potassium, and magnesium, are low or high (this can be determined from a blood test).
- If you have kidney disease .
- If you have liver disease .
- If you have a condition called Lupus .
- If you have an allergy to this chlorothiazide medicine, to medicines containing sulfa, or to any other medicine, food, or dye.
- If you are pregnant or expecting a baby .
- If you are a breastfeeding mother .
It is very important for your safety to tell the doctor without hiding this information.
How to use the medicine correctly?
This usually comes in the form of a liquid (oral suspension), so keep these instructions in mind.
- Shake well: Before taking the medicine, you should shake the bottle well. This will ensure that the medicine is thoroughly mixed throughout the liquid.
- Correct measurement: Use only the special syringe, spoon, or dropper given to you by your doctor to measure your medicine. Never use teaspoons or tablespoons from the kitchen. They are not accurate.
- Time: Try to take your medicine at the same time every day, as your doctor told you.
- With or without food: This can be taken before or after meals. However, if you experience stomach upset, it is best to take it with food.
- Don't stop: Don't stop taking the medicine until your doctor tells you to. Even if you feel better, continue taking it for the prescribed period.
What if I accidentally take too much medicine?
If you think you have accidentally taken too much medicine, immediately call the National Poisons Information Centre at the Colombo National Hospital or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
What if I miss a dose of medication?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Never take a double dose.
Other drugs that may interact with this medicine (Drug Interactions)
It is very important to inform your doctor about all medications you are taking, as some medications can interact with chlorothiazide and cause adverse effects.
| Drug type | Examples |
|---|---|
| Some sleeping pills and anti-seizure medications (Barbiturates) | Phenobarbital |
| Lithium | Used for mental illness |
| Diabetes medication | Metformin, Insulin, Glibenclamide |
| Medications for high cholesterol | Cholestyramine, Colestipol |
| Painkillers and anti-inflammatory drugs (NSAIDs) | Ibuprofen, Naproxen, Diclofenac |
| Steroid-type medications | Prednisone, Cortisone |
This list is not complete. Tell your doctor about all medications, vitamins, and traditional medicines you are taking. Also, tell them if you smoke or drink alcohol.
Things you should be careful about when taking medication
- Go for regular check-ups: Stay in touch with your doctor to monitor your progress. Go to the clinic on the scheduled days.
- Measure your blood pressure: Measure your blood pressure at home as your doctor tells you. Ask your doctor what your blood pressure should be and what to do if it changes.
- Be careful with water retention: If you are very sick, vomiting, or sweating profusely, you should be very careful. Because at that time, a large amount of fluid is released from the body. It can be dangerous with this medicine. In such a case, seek advice from your doctor.
- Food and drink: You may be asked to follow a special diet while taking this medicine. Ask your doctor how many glasses of water you should drink per day.
- Drowsiness/Dizziness: This medication may make you feel drowsy or dizzy. Therefore, do not drive or operate machinery until you know how this medication affects you. Be careful when getting up suddenly from a sitting position or getting out of bed, especially if you are an elderly person.
- No alcohol: Alcohol can interfere with the effectiveness of this medicine. Therefore, avoid drinking alcohol.
- Do not self-medicate for other illnesses: Do not self-medicate for things like coughs, colds, or body aches without consulting your doctor. Some painkillers can increase blood pressure.
What side effects might I experience?
Like any medicine, this can cause side effects. Although not everyone gets them, watch out for the following symptoms.
| Serious side effects that should be reported to the doctor immediately | |
|---|---|
| Allergic reactions | Skin rash, itching, swelling of the face, lips or tongue. |
| Changes in heart rate | Difficulty breathing, chest pain, dizziness, feeling like your heart is beating fast or irregularly, fainting. |
| Kidney damage | Difficulty urinating or a change in the amount of urine you pass. |
| Low blood pressure | Dizziness, fainting, feeling unusually tired or weak. |
| Serious skin reactions | Skin redness, blistering, peeling (even inside the mouth). |
| Side effects that are usually not dangerous, but should be reported to the doctor if they persist | |
| Stomach ache | Diarrhea, vomiting. |
| High blood sugar | Increased hunger, thirst, or urination; unusual tiredness, blurred vision. |
| Other features | Excessive thirst, loss of appetite, muscle aches or pains, and unusual sweating. |
Take-Home Message
- Chlorothiazide is a medication that should only be taken under the advice of a doctor. Take the prescribed dose at the prescribed time.
- Never share your medicine with others. It may be harmful to them.
- Tell your doctor about all other medications you take and all medical conditions you have.
- If you notice any serious side effects or signs of an allergy, seek medical advice immediately.
- If you take too much medicine, immediately go to the National Poisons Information Centre or the nearest hospital Emergency Department (ETU).


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