Are you feeling a little nervous and unprepared for your baby's arrival? Sometimes the doctor says, "Your cervix hasn't opened yet, let's help a little." At times like these, today we're talking about a special medicine that helps soften and open your cervix to make it easier for labor. This is called Dinoprostone gel.
What is Dinoprostone?
Simply put, Dinoprostone is a medicine that is made to mimic a chemical called Prostaglandin that is naturally present in our bodies. It usually comes in the form of a gel. Its main function is to soften and gradually open the cervix of a mother who is nearing the end of her pregnancy and is close to giving birth, helping her to start labor.
Think about it, the cervix is the doorway through which the baby can come out. That doorway needs to open properly for the baby to come out easily. Sometimes it's too late to open that doorway. That's when doctors use this Dinoprostone gel to help open that doorway.
What should I tell the doctor before giving this medicine?
To determine if this treatment is right for you, it is extremely important for your doctor to know your complete medical history. If you have any of the following conditions, you should definitely tell your doctor about them.
| Situations you should report |
|---|
| If you currently have an infection in the vagina, uterus, or pelvic area. |
| Low hemoglobin in the blood (anemia). |
| Glaucoma condition. |
| If you have heart disease, high blood pressure, kidney disease, or liver disease. |
| Lung or respiratory diseases such as asthma. |
| Placenta Previa. |
| If you have had a previous difficult birth, or if you had a cesarean section. |
| If you have had previous surgery on your uterus or if you have scars. |
| If you have a seizure disorder. |
| If you are currently bleeding from the vagina. |
| If you have previously given birth to 6 or more children. |
| If you have an allergic reaction to dinoprostone, prostaglandins, or other medicines, foods, or dyes. |
| If you are a breastfeeding mother. |
How do you use this medicine?
This is the most important thing you need to know. This medicine should never be used at home. It should only be given in a hospital or clinic by a doctor or trained nursing staff.
The doctor or nurse will apply this gel to your cervix through your vagina. You will then be asked to lie down for 15 to 30 minutes. The doctor will stop giving you this medicine when your cervix is dilated enough for labor to begin, or when you are actually in labor.
This medicine is given in a hospital, under medical supervision only. Therefore, there is no need to worry about an overdose. The medical team is fully aware of this. If there is any suspicion of such a thing, they will take the necessary steps. For example, if necessary, they know how to call the National Poison Information Center at the Colombo National Hospital and seek advice.
What are the possible side effects?
Like any medicine, this can cause side effects in some people. But don't worry, you are under the supervision of doctors and nurses at the hospital. So if anything happens, they will take care of it.
| Type of side effect | Description |
|---|---|
| Things to report to the doctor/nurse immediately | |
| Allergic Reactions | Skin rash, itching, swelling of the face, lips or tongue. |
| Breathing difficulties | Difficulty breathing. |
| Other serious symptoms | Chest pain, dizziness or fainting, fever over 38 degrees Celsius (100.4 Fahrenheit). |
| Vaginal problems | Unusual or foul-smelling discharge, heavy bleeding, pelvic pain, or severe back pain. |
| Things that are usually not serious, but should be reported if they persist | |
| Digestive system | Vomiting, nausea, diarrhea. |
| Other minor features | Headache, slight increase in body temperature (which later disappears). |
What other medications may interact with this medicine?
Another drug that can interact with this medication is Oxytocin. You may have heard that "they give you saline to make you feel pain." That's what Oxytocin is added to the saline. Since both of these drugs cause the uterus to contract, doctors are very careful when they give these two together. They know exactly the time gap that needs to be left between the two. So don't worry about it. Don't forget to tell your doctor about any other medications you're taking.
Take-Home Message
- Dinoprostone is a medication that is given to help the cervix soften and open to help start labor.
- This is never used at home. It is only given in a hospital under medical supervision .
- Before you are given this medicine, it is imperative that you tell your doctor about all your medical conditions (especially if you have had a previous cesarean section).
- The medical team will closely monitor you and your baby's heartbeat while the medication is being given.
- If you experience any unusual symptoms (excessive pain, heavy bleeding), notify your doctor or nurse immediately.
- If you have any further questions about this, don't hesitate to ask your doctor.


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