What you need to know about this medicine for diarrhea (Diphenoxylate; Atropine)

What you need to know about this medicine for diarrhea (Diphenoxylate; Atropine)

One of the health problems we often face is diarrhea, or loose stools. At times like these, a doctor may give us a medicine called this, or as many people know it, a medicine like 'Lomotil'. However, like any medicine, there are a few things we need to be aware of when using this. So today, let's talk about this medicine, what it does, how to use it, and what things to be careful about.

What is this medicine? Let's find out simply.

This is actually a combination of two drugs: Diphenoxylate and Atropine . Simply put, this is an antidiarrheal drug.

This works by controlling the activity of your intestines a little and slowing it down. Imagine, when you have diarrhea, your intestines are working very fast. This medicine slows down that speed and reduces the number of times you have to go to the bathroom. This is the main function of this medicine. But sometimes your doctor may prescribe it for other reasons.

Things to tell your doctor before taking this medicine

Before using this medicine, it is very important to give your doctor a complete description of your health condition, as this medicine may not be compatible with some medical conditions.

The most important thing is to tell your doctor clearly about all your medical conditions and any other medications you are taking. Don't hide anything.

If you have any of the following conditions, be sure to tell your doctor about them.

Health condition or opportunity Why do you need to tell the doctor?
Food poisoning caused by a bacterial infection Slowing down the bowel movement at a time like this can allow the infection to stay in the body longer.
Diseases such as colitis These types of illnesses can become severe.
Dehydration If you are already dehydrated due to diarrhea, you should treat that first.
Down's syndrome The effects of the medication may vary for people with this condition.
Jaundice or other liver diseases The process of removing this medicine from the liver may be affected.
If you are pregnant, trying to get pregnant, or are a breastfeeding mother It is essential to seek medical advice as it may affect the baby.
If you have allergies to other medicines, foods, or substances There is a possibility of an allergy to this medicine as well.

How should I use the medicine?

This is an oral medication. Take only the prescribed dose as prescribed by your doctor. Never increase or decrease the dose.

  • If this is a liquid, use a specially marked measuring spoon or dropper. Do not use household teaspoons or table spoons, as they are not accurate.
  • Take your medicine on time.
  • Once your diarrhea is under control, your doctor may reduce the dosage of your medication. Follow those instructions.
  • If given to children: Special care is required when giving this medicine to children. Therefore, do not give it to children without the advice of a doctor.

What to do if you overdose on medicine?

If you think you have taken too much medicine, go to the nearest hospital Emergency Department (ETU) immediately . Or call the National Poisons Information Centre at the Colombo National Hospital . This can be a very dangerous situation.

What to do if you miss a dose of medication?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the regular time. Never take two doses at the same time.

Other things that may interact with this medicine (Interactions)

When taking this medicine, it may interact with other things you are taking. Therefore, tell your doctor about all the medicines you are taking (including vitamins and herbal remedies).

  • Alcohol
  • Allergy, cough, and cold medications (Antihistamines)
  • Some sleep-inducing and anti-epileptic medications (Barbiturates)
  • Medications for conditions such as depression and anxiety
  • Medications for movement disorders such as Parkinson's disease
  • Muscle relaxants
  • Painkillers (especially opioids)

This list is not complete. Therefore, it is safest to tell your doctor about everything you take.

Things to keep in mind while taking the medicine

Be aware of symptoms.

If your diarrhea doesn't improve after taking this medicine for two days, call your doctor right away. You may have a problem that needs other treatment. Also, if you develop a fever or have blood in your stool, see a doctor right away.

Drowsiness and dizziness

This medicine may make you feel drowsy or dizzy. So , do not drive or operate machinery until you know how this medicine affects you. Be careful when standing up or getting up from a sitting position, especially if you are elderly. You may feel dizzy or fall. Drinking alcohol can make this condition worse.

Dry mouth and dehydration

It's common to have a dry mouth from medication. Chewing sugar-free gum, sucking on unsweetened candy, and drinking plenty of water can help. Diarrhea can cause your body to lose a lot of water, so it's important to drink plenty of water to prevent dehydration.

Side effects that may occur due to medication

Like any medication, this one can have side effects. Some are serious, some are common.

Side effect Description
Side effects that you should report to your doctor immediately
Allergic reactions Skin rash, itching, swelling of the face, lips, tongue or throat.
Anticholinergic toxicity Redness of the face, blurred vision, dry mouth and skin, confusion, rapid or irregular heartbeat, difficulty urinating, constipation.
Central nervous system depression (CNS depression) Slow or shallow breathing, difficulty breathing, fainting, dizziness, confusion, difficulty staying awake.
If it persists or is bothersome, tell your doctor.
Confusion Problems with memory and comprehension.
Drowsiness Unusually sleepy.
Dizziness Feeling dizzy.
Feeling of unusual happiness (Euphoria) Feeling excessive happiness or excitement for no reason.
Stomach pain Abdominal discomfort or pain.

How to keep medicine safe?

This is very important. Do not leave this medicine where children can get it. If an adult, child, or pet accidentally takes this medicine, it can even cause death.

  • Since this medicine can be misused, keep it in a safe place that can be protected from theft.
  • Do not share this medicine with anyone else for any reason. Selling or giving this medicine to anyone else is illegal and dangerous.
  • If you are disposing of leftover medication: Mix it with something like used cat litter or coffee grounds, put it in a tightly sealed container, such as a coffee can, and discard it.
  • Store at room temperature (between 15-30 degrees Celsius). Do not refrigerate. Protect from light and keep the bottle cap tightly closed.

Take-Home Message

  • This medicine should only be used on the advice of a doctor. Follow the prescribed dosage and duration.
  • Inform your doctor about any other medical conditions you have and all medications you are taking.
  • Avoid driving as the medicine may make you feel drowsy. Do not drink alcohol.
  • If you experience a serious side effect such as difficulty breathing or facial swelling, go to a hospital's Emergency Department (ETU) immediately.
  • Keep this medicine in a safe place out of the reach of children. Never share it with others.

Diarrhea, stomach upset, Lomotil, diphenoxylate, atropine, diarrhea medication, side effects

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