Do you sometimes experience severe pain in the upper right abdomen, along with fever and weakness? Does this pain seem to get worse when you breathe or move around? If so, this is not something you should ignore. Today we are going to talk about a condition that many people have not heard of, but can occur in women, especially young women. That is Fitz-Hugh-Curtis Syndrome.
What is Fitz-Hugh-Curtis Syndrome?
Simply put, Fitz-Hugh-Curtis Syndrome is an inflammation of the liver capsule, which is a swelling. The main cause of this is pelvic inflammatory disease, also known as PID. PID occurs when a bacterial infection enters your reproductive system, such as the uterus and fallopian tubes. This causes pain and swelling in that area.
Now imagine, what happens if the inflammation, or infection, caused by PID spreads outside your pelvic cavity and goes right to your liver? That's when a condition called Fitz-Hugh-Curtis Syndrome (FHCS) occurs. This is when violin-string-like adhesions form between the membrane surrounding your liver, the lining of your abdominal cavity, or your diaphragm, the muscle that helps you breathe. These adhesions are what cause that upper right abdominal pain.
This condition is often seen as a complication of sexually transmitted infections (STIs) such as gonorrhea and chlamydia . However, it is not common and is quite rare. Sometimes your doctor may also call it ' perihepatitis' .
How common is this condition?
In fact, Fitz-Hugh-Curtis Syndrome is not very common, even among women of childbearing age. However, it has been found that between 4% and 14% of women with pelvic inflammatory disease (PID) may develop this condition.
But here's the thing. Young women, especially those under the age of 25, who develop PID, are at a higher risk of developing FHCS. This is because at that age, the reproductive organs are not yet fully developed, making them more susceptible to infection. Some studies have shown that as many as 27% of young women with PID may develop the condition. It is very rare in men.
What are the symptoms of Fitz-Hugh-Curtis Syndrome?
The main and most common symptom is a sharp pain in the upper right side of your abdomen . To be precise, it's right under your ribs. The reason for this pain is that the membrane around the liver, as we talked about earlier, swells and sticks to the inside of the abdominal cavity. This pain can get worse when you breathe, move, or cough. Some people may feel a stabbing pain.
Apart from that, there may be several other symptoms. They are:
- Lower abdominal pain (this is the pain caused by PID)
- Pelvic pain
- Back pain
- Fever and chills
- Nausea and vomiting
- Abnormal vaginal discharge – possibly with a foul odor
- Pain during sexual intercourse
- Pain or burning sensation when urinating
- Feeling of tightness or cramping in the stomach muscles
- Bleeding after sex
- Headache
- Hiccups (this is a less common symptom)
Most importantly: If you have one or more of these symptoms, especially if you have a fever along with pain in the upper right side of your abdomen, you should see a doctor immediately. These can also be symptoms of other illnesses, so it's important to find out exactly what's wrong.
What causes Fitz-Hugh-Curtis Syndrome?
The primary cause of Fitz-Hugh-Curtis syndrome (FHCS) is the pelvic inflammatory disease (PID) we talked about earlier. PID is an inflammation of the pelvic organs, such as your uterus, fallopian tubes , and ovaries, caused by a bacterial infection.
Now, there are many reasons why PID can occur. Most of the time, PID is caused by sexually transmitted infections (STIs) . Among them, two types of bacteria , Gonorrhea and Chlamydia, are mainly responsible for this. However, PID can also be caused by other types of bacteria.
Usually, the infection in PID is limited to the pelvic cavity. However, sometimes, this infection or inflammation can spread outside the pelvic cavity. This is when it spreads and affects the tissues around the liver, which is what causes FHCS. Strictly speaking, the infection does not go directly to the liver, but affects the membrane that surrounds the liver.
What are the risk factors for this?
For a condition called Fitz-Hugh-Curtis syndrome (FHCS) to occur, PID must first develop. So the same risk factors that affect the development of PID also affect FHCS. Let's see what they are:
- Having multiple sexual partners: The more partners you have, the greater the risk of contracting a sexually transmitted infection (STI).
- Having unprotected sex: Having sex without using a barrier method like a condom increases the risk of contracting STIs.
- Having had sexually transmitted infections (STIs) before: If you have had diseases like gonorrhea or chlamydia before, you are more likely to get them again and develop into PID.
- Previous pelvic inflammatory disease (PID): People who have had PID before can get it again.
- Using an intrauterine device (IUD): Some studies have shown that the risk of PID may be slightly increased during the first few months of using an IUD. But this is not common for everyone. If you are using an IUD, talk to your doctor about this.
- Vaginal douching: Some people use various liquids to clean their vagina. This destroys the natural good bacteria in the vagina and allows bad bacteria to grow, which increases the risk of PID.
- Being a woman under the age of 25: As we've talked about before, this risk is higher for younger people, especially young, sexually active girls.
If you have these risk factors, it's best to be a little careful.
What are the possible complications of Fitz-Hugh-Curtis Syndrome?
Fitz-Hugh-Curtis syndrome (FHCS) is a complication of PID. So if FHCS is not treated properly, it can lead to other problems. And PID can also cause other complications.
Possible complications in the short term are:
- Endometritis: This is an inflammation of the inner layer of the uterus.
- Salpingitis: This is an inflammation of the fallopian tubes.
- Tubo-ovarian abscess: This is a lump-like collection of pus in the fallopian tubes or ovaries.
- Pelvic peritonitis: This is an inflammation of the membrane that lines the pelvic cavity.
In addition to this, there can be long-term effects, which are the most dangerous.
- Infertility: This is one of the most serious complications of PID and FHCS. PID can cause scar tissue to form in the fallopian tubes. This scarring can block the tubes, making it impossible for a sperm to meet an egg, making it impossible for a baby to be born.
- Persistent pain: Persistent pain in the pelvic cavity can occur. This can interfere with daily activities.
- Bowel obstruction: In FHCS, the adhesions that form around the liver can sometimes affect the intestines and block them. This can be severe enough to require emergency surgery.
- Ectopic pregnancy: When the fallopian tubes are damaged, the fertilized egg can start growing in the fallopian tube instead of reaching the uterus. This is a life-threatening emergency.
That's why we say that if you have symptoms like these, it's very important to seek treatment without delay .
How does Fitz-Hugh-Curtis Syndrome affect fertility?
To put it bluntly, Fitz-Hugh-Curtis Syndrome (FHCS) can indirectly affect fertility if not treated properly. How do you know? The main cause of FHCS is PID. This PID condition is also the main cause of infertility.
PID causes scar tissue to form in your fallopian tubes. Think of these tubes as little tubes. When these tubes become scarred, they can become blocked. This makes it difficult for sperm to find an egg, or for a fertilized egg to reach the uterus. This can reduce your chances of getting pregnant. So, since FHCS is a result of PID, there is also a risk of miscarriage.
How is Fitz-Hugh-Curtis Syndrome diagnosed?
To be honest, diagnosing Fitz-Hugh-Curtis syndrome (FHCS) can be a bit tricky. The reason is that its symptoms are very similar to those of other conditions. For example, that upper right abdominal pain can also be caused by conditions like gallstones (cholecystitis ), viral hepatitis , renal colic , and appendicitis .
Therefore, your doctor will need to do several tests to confirm that this is FHCS. They will also need to rule out other conditions.
The tests usually performed are:
- Pregnancy test: Because this kind of pain can also occur in an ectopic pregnancy.
- Complete blood count (CBC): This can check for infection in the body.
- Comprehensive metabolic panel (CMP): This is a blood test that can provide information about many things, such as liver function.
- Vaginal smear: To find out what bacteria caused PID.
- Tests for sexually transmitted diseases (STIs): Check for diseases like gonorrhea and chlamydia.
In addition, some radiological tests may also be performed:
- CT scan
- Transvaginal ultrasonographic scan: This involves inserting a small instrument through the vagina to view the pelvic organs.
- MRI
If all these tests are not enough to make a clear diagnosis, the doctor may need to perform either laparoscopic surgery or regular open surgery. Laparoscopy involves making a few small incisions in the abdomen and inserting a camera. If the violin string-like adhesions around the liver are seen, it can be confirmed that it is Fitz-Hugh-Curtis syndrome (FHCS).
How is Fitz-Hugh-Curtis Syndrome treated?
The doctor mainly prescribes antibiotics as a treatment for this. Because this is caused by a bacterial infection, the first thing they try to do is eliminate the infection. Usually, these antibiotics are given for about one or two weeks.
They will also prescribe medication to reduce your pain .
However, sometimes these antibiotics alone do not get rid of the adhesions that have formed around the liver. If that happens, that is, if the antibiotics do not provide much relief, the doctor will have to perform surgery to remove the adhesions. This can be done either through laparoscopic surgery or through regular open surgery. With laparoscopic surgery, you can recover quickly and go home.
What should I do after treatment?
Even after treatment is complete, you should follow these steps to prevent further complications:
- Avoid having sex during treatment and until your doctor says it's safe. This is very important, as you need to wait until the infection is completely gone.
- Take all antibiotics prescribed for you exactly as your doctor tells you, for the full duration of your treatment. Don't stop taking the medication just because you feel better.
- If there is pain, apply a hot water bottle. It will provide relief.
- Rest well until the fever and pain subside.
- Talk to any sexual partners you had in the two months before you started having these symptoms. Ask them to get tested for sexually transmitted infections (STIs). This is very important, because if you don't, you could get the infection again and spread it to others.
- See your doctor again in about three days to check how you are doing.
If you follow these instructions correctly, you can recover quickly and prevent this type of problem from happening again.
What can I expect if I have Fitz-Hugh-Curtis Syndrome?
Usually, Fitz-Hugh-Curtis syndrome (FHCS) can be completely cured with antibiotics. Also, these treatments do not have major side effects. However, if treatment is started late, or if it is not treated properly, the complications we discussed earlier can occur. That is why it is important to diagnose the disease and get treatment as soon as possible.
How can I reduce the occurrence of this?
The best ways to prevent the development of Fitz-Hugh-Curtis syndrome (FHCS) are:
- Use a condom every time you have sex. This can go a long way in preventing the spread of sexually transmitted infections (STIs).
- If you are sexually active, get tested regularly for sexually transmitted infections (STIs). Some STIs can be present even if you don't have any symptoms.
- Ask your sexual partners to get tested for STIs as well.
- Avoid washing your vagina. The vagina has a natural way of cleaning itself.
By following these tips, you can also reduce your risk of developing pelvic inflammatory disease (PID), because without PID, FHCS cannot develop.
What time should I see my doctor?
If you have one or more of the following symptoms, see your doctor immediately:
- If a new fever develops, or if an existing fever increases.
- If you have unusual vaginal bleeding.
- If you have new or worsening abdominal or pelvic pain.
- If the amount of vaginal discharge has increased, or if it has a bad odor.
- If you feel dizzy, spinning, or fainting.
Emergency! Call 1990 (Sri Lanka's Suwaseriya Ambulance Service) if you have any of these symptoms:
These could be signs of a dangerous condition called sepsis , which is the body's overreaction to an infection.
- Difficulty breathing.
- If your body feels very heavy.
- Very severe pain.
- Heart rate increases.
- If the skin is cold, pale, and appears sweaty.
- If you feel disoriented and desperate.
- If you are very sleepy or difficult to wake up.
- If you faint.
In an emergency like this, don't delay. You need to go to a hospital immediately.
Is Fitz-Hugh-Curtis Syndrome a sexually transmitted disease (STI)?
No, Fitz-Hugh-Curtis syndrome (FHCS) is not, strictly speaking, a sexually transmitted infection (STI). However, it is closely related to sexually transmitted diseases (STIs). How? The main cause of FHCS is pelvic inflammatory disease (PID). The main cause of PID is STIs like Gonorrhea and Chlamydia.
Simply put, PID and FHCS are two ways your body responds to an infection. They are not the infection itself.
Important thing to remember: Anyone can get a sexually transmitted infection (STI) if you have unprotected sex. Even if you have only one partner, they can still have an STI without knowing it. Women, in particular, can have STIs like gonorrhea without any symptoms. STIs can cause painful complications like Fitz-Hugh-Curtis Syndrome (FHCS), so it's important to practice safe sex and get tested regularly.
FHCS is a painful condition. But a doctor can treat it with antibiotics and painkillers. You may feel embarrassed or afraid to talk to your doctor about your sexual health. But there is nothing more important than your health. Put aside your embarrassment and fear and talk to your doctor about your concerns.
If you are diagnosed with Fitz-Hugh-Curtis Syndrome (FHCS), be sure to inform your sexual partners so they can also be tested and treated if necessary.
Brief points to remember
We hope you now have a better understanding of what we've been talking about, Fitz-Hugh-Curtis Syndrome (FHCS). While it may seem a bit complicated, here are some key things to remember:
- FHCS is a complication of pelvic inflammatory disease (PID). PID is often caused by sexually transmitted infections (STIs) such as gonorrhea and chlamydia.
- The main symptom is severe pain in the upper right abdomen. It may also be accompanied by fever and nausea.
- If you have these symptoms, see a doctor without delay. Early treatment can prevent dangerous complications such as miscarriage.
- Practice safe sex. Use condoms. Get tested for STIs regularly.
- Tell your partners about this honestly. They should get tested too.
- Don't delay seeking treatment because of embarrassment. Your health is the most important thing.
We hope this information is useful to you. Stay healthy!
` Fitz-Hugh-Curtis Syndrome, Pelvic Inflammatory Disease, PID, Sexually Transmitted Diseases, STIs, Women's Health


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