Sometimes, fungal infections in our bodies cannot be cured with ordinary pills, right? Sometimes, such infections can occur on the skin, nails, mouth, or even inside the body. In such cases, the doctor may recommend an injection into a vein. Fluconazole is a very powerful drug that can control and cure such severe fungal infections. So, today we will talk about this drug, its action, things to be careful about, and side effects.
What is Fluconazole?
Simply put, fluconazole is a drug that belongs to the antifungal class. Its main function is to destroy or stop the growth of fungal cells that grow in our body.
Think of it like a special weapon that targets only the enemy called fungus. Therefore, this medicine cannot cure the common cold, the flu, or other illnesses caused by bacteria or viruses. There are separate treatments for those.
Although this medicine is usually available as a pill, if the infection is severe or if the medicine needs to be absorbed into the body quickly, doctors use it as an injection into a vein.
Things you need to tell your doctor before taking medicine
Before you are given fluconazole, it is very important to give your doctor a complete description of your health condition, especially these things.
- Heartbeat abnormalities: If you have an irregular heartbeat.
- Kidney disease: If you have any kidney disease.
- Liver disease: If you have any liver disease.
- Low potassium levels: If you have previously been diagnosed with low potassium levels in your blood.
- Allergies: Tell your doctor if you have had an allergy to fluconazole or other antifungal medications in the past. Also, tell your doctor if you have any allergies to other foods, medications, or substances.
- Pregnancy: If you are pregnant or expecting a baby soon.
- If you are a nursing mother: If you are a mother who is breastfeeding a child.
Based on this information, your doctor will decide whether this medication is right for you or whether the dosage needs to be changed.
How do you use this medicine?
This is an injection that is injected into a vein. Therefore, this treatment is usually given in a hospital or clinic. A nurse or doctor will give you this injection.
However, in rare cases, if you need to receive this vaccine at home, the hospital will provide you with the necessary training. If so, follow the instructions given exactly . Take only the prescribed dose at the prescribed time.
Never throw used needles and syringes in the trash. Put them in a specially designated sharps container . If you don't have one, ask your doctor about how to get one.
What if I overdose?
If you think you have taken too much of this medicine, call the National Poisons Information Centre at the National Hospital in Colombo immediately . Or go to the Emergency Department (ETU) of the nearest hospital. Do not delay.
Other medications that may interact with Fluconazole
Fluconazole can interact with many other medications, so it is important to tell your doctor about all the medications you are taking (including those prescribed by other doctors, over-the-counter medications, traditional medicines, vitamins, and herbal products).
| Drug category | Description and examples |
|---|---|
| Do not take Fluconazole with this medicine! | |
| Various medications | Drugs like Flibanserin, Lomitapide, Lonafarnib, Triazolam. |
| Drugs that affect heart rate | Any other medication that prolongs the QT interval of the heart. |
| Problems can occur with this medication - tell your doctor | |
| Antibiotics | Rifabutin, such as Rifampin. |
| Medicines for HIV or Hepatitis | Some antiviral drugs. |
| Blood pressure and heart disease medications | Some types. |
| Medications for cholesterol | Such as Atorvastatin, Lovastatin, Simvastatin. |
| Diabetes medication | Such as Glipizide, Glyburide. |
| Medicines for seizures | Such as Carbamazepine, Phenytoin. |
| Anticoagulant | Like Warfarin. |
| Painkillers | NSAIDs like Ibuprofen and Naproxen and narcotic painkillers like Fentanyl and Methadone. |
| Other medications | Many other drugs such as Cyclosporine, Tacrolimus, Sirolimus, Prednisone, Theophylline, Vitamin A. |
Side effects that may occur when taking the medicine
Like any medicine, fluconazole can cause side effects in some people. Some of these are serious, while others are mild.
| Side effects that you should report to your doctor immediately | |
|---|---|
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Changes in heart rate | Feeling like your heart is beating fast or irregularly, dizziness, chest pain, difficulty breathing. |
| Symptoms of liver injury | Pain in the upper right side of the stomach, loss of appetite, nausea, pale stools, dark yellow or brown urine, yellowing of the eyes or skin, and extreme fatigue. |
| Severe skin reactions | Skin redness, blistering, peeling (even inside the mouth). |
| Other serious symptoms | Seizures , fever with swelling of the extremities, symptoms of adrenal insufficiency (nausea, vomiting, loss of appetite, extreme fatigue, dizziness). |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
| |
Special warning about alcohol!
Avoid drinking alcohol completely while taking this medication. Combining alcohol and fluconazole can increase the risk of liver damage. Therefore, it is important for your own safety to stay away from alcohol during treatment.
Take-Home Message
- Fluconazole is a powerful medication for fungal infections. It should only be taken on medical advice.
- Be sure to tell your doctor about any other medical conditions you have and all other medications you are taking.
- Avoid alcohol completely during treatment.
- If you experience any serious side effects such as skin rash, difficulty breathing, yellowing of the eyes, or dark urine, seek medical advice immediately.
- This medicine is for you only. Never share it with others.


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