It is a very painful experience to see our mother, father, or someone we love gradually forget everything due to Alzheimer's disease. In such a situation, doctors recommend certain medications to control the course of the disease and make daily life easier. Galantamine is a special medicine that helps with memory problems. Let's talk about this simply today.
What exactly is this drug called Galantamine?
Simply put, this is a drug that is given to treat mild to moderate dementia caused by Alzheimer's disease. It cannot completely cure Alzheimer's disease. However, this drug improves the functioning of certain chemicals (neurotransmitters) in the brain, helping the patient maintain a certain level of memory, attention, and ability to perform daily tasks.
The important thing is that this is a medication that manages symptoms, not a cure for the disease. However, it can significantly improve the patient's quality of life.
In Sri Lanka, you may find this medication under brand names such as Razadyne, Razadyne ER, and Reminyl.
Things you need to tell your doctor before starting this medication
Before giving this medicine to you or your patient, your doctor will want to know your complete health history. It is especially important to tell them about any of the following conditions.
- If you have asthma or other lung diseases.
- If you have any difficulty urinating or a problem with the prostate gland.
- Heart disease , especially if you have a slow heartbeat.
- If you have any kidney or liver disease.
- If you have had a seizure (episode) before.
- If you have digestive system diseases such as stomach ulcers and gastritis.
- If you have any allergies to this Galantamine medication, any other medication, food, or dye.
- If you are pregnant, trying to get pregnant, or breastfeeding .
Based on this information, your doctor will determine the most appropriate dosage and treatment plan for you.
How should I use the medicine exactly?
This usually comes as an extended-release capsule that is taken once or twice a day.
- Take with a meal: To reduce the risk of stomach upset, always take this medicine with or after a meal.
- Drink plenty of water: Drink a good glass of water while taking the medicine.
- Swallow the capsule whole: Never break, crush, or chew it. Doing so may affect the effectiveness of the medicine.
- Take it on time: Try to take your medicine at the same time every day, as prescribed by your doctor.
- Don't stop halfway: Even if you or the patient feel better, avoid stopping the medication without consulting your doctor.
What to do if you miss a dose of medication?
Take the missed dose as soon as you remember. But if it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Never take a double dose. If you have missed more than three days of taking the medicine, consult your doctor before starting again.
What if you take too much medicine? (Overdose)
If you think you have taken too much medicine, it is an emergency. Go to the nearest hospital Emergency Department (ETU) immediately . Or call the National Poisons Information Centre at the Colombo National Hospital for advice.
What are the possible side effects?
Like any medication, Galantamine can cause side effects in some people. Although most of these are minor, there are some things to be aware of.
| Side Effect | Description and what to do |
|---|---|
| Serious side effects that require immediate medical attention | |
| Allergic Reactions | Skin rash, itching, swelling of the face, lips or tongue. |
| Heart rate changes | Feeling like your heart is beating too slowly, palpitations, fainting, and dizziness. |
| Serious skin reactions | Redness, blistering, peeling skin (can also occur inside the mouth). |
| Digestive system problems | Severe stomach pain, severe diarrhea, vomiting, unusual weight loss. |
| Abnormal bleeding | Bruising, red or purple spots on the skin. |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
| Nausea | It is common when you first start taking the medication. It can be reduced by taking the medication with food. |
| Appetite | Decreased desire to eat. |
| Headache and mild diarrhea | These can also occur and disappear in the early stages. |
What else should you be concerned about?
- Other medications: Tell your doctor about all the medications you are taking (over-the-counter medications, vitamins, and herbal remedies), as some medications may interact with Galantamine.
- Drowsiness: This medication may cause drowsiness and dizziness in some people. Therefore, until you know how this medication affects you, avoid driving or operating machinery.
- Regular check-ups: The doctor should be seen regularly to check on the patient's condition. Therefore, do not miss the clinic dates given by the doctor.
- Storage: Keep out of reach of children . Store at room temperature, away from excessive heat and moisture. Do not use expired medicine.
Alzheimer's disease is a challenge for both the patient and their caregivers. Therefore, it is very important to be properly informed about such medications and follow the doctor's instructions.
Take-Home Message
- Galantamine is a medication used to manage dementia caused by Alzheimer's disease, but it does not cure the disease.
- Always take your medicine exactly as your doctor has prescribed, with a meal. Do not break, crush, or chew the medicine.
- Inform your doctor about all other medications you are taking and any other medical conditions you may have.
- Avoid driving until your body adjusts to the medication, as it may cause drowsiness or dizziness.
- If you experience any serious side effects such as severe skin allergies, slow heartbeat, or fainting, inform your doctor immediately.
- Never stop taking medication or change the dosage without medical advice.


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