When you take a blood test report, you may have seen that along with the cholesterol values, there is also a value called `Triglycerides`. Sometimes, the doctor may say that your triglyceride level is a little high and that you need to control it. In such a case, along with a balanced diet and exercise, the doctor may prescribe you a medicine called Icosapent ethyl. So today, let's talk about this medicine, as simple as talking to a friend.
Simply put, what is Icosapent ethyl?
Icosapent ethyl is an essential fat for our body. To be precise, it is a highly purified form of Omega-3 fatty acid. Its main function is to reduce the level of triglycerides, a type of fat in your blood. Since triglyceride levels are too high, it is important to control them, as they can lead to heart disease and other health problems.
The most important thing is that taking this medicine alone is not enough . As the doctor says, you must also maintain your diet and exercise . This medicine is just an additional support for that healthy lifestyle.
This medicine is most commonly seen in Sri Lanka and around the world under the brand name `VASCEPA`.
Things you need to tell your doctor before starting medication
Before giving you this medicine, your doctor will ask you a few questions. However, if you have any of the following conditions, you should definitely inform your doctor about them. This is very important for your safety.
| If you have these conditions, | Please inform the doctor. |
|---|---|
| Allergy to fish or seafood | Because this medicine is made from fish oil, it is very important if you have allergies to things like fish or shellfish. |
| Liver disease | Please tell us if you have any liver disease. |
| Bleeding disorders | If you have a condition that prevents blood from clotting easily or a tendency to bleed. |
| Irregular heartbeat | If you have ever had any abnormal heart rate or rhythm. |
| Pregnancy or expecting a child | If you are pregnant or expecting a baby, it is imperative that you tell your doctor. |
| Breastfeeding | If you are a mother who is breastfeeding your child, please also mention that. |
How exactly do you use this medicine?
To get the most out of a medicine, you need to use it correctly.
- It is very important to take this medicine with a meal . Swallow the capsule whole with a glass of water.
- Never break, crush, dissolve, or chew this capsule. This capsule is designed to slowly dissolve in the body and release the medicine. So take it as is.
- Take the prescribed dose at the time prescribed by your doctor. Make a habit of taking it at the same time every day without skipping any time.
- Even if you feel better, do not stop taking the medicine without your doctor's advice .
What if the dosage of the medicine is increased? (Overdosage)
If you think you have taken too much medicine, don't panic. Go to the nearest hospital Emergency Department (ETU) immediately. Or call the National Poisons Information Centre at the Colombo National Hospital for advice.
What if I forget to take my medicine?
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Never take two doses at once to make up for a forgotten dose.
Other medications that may interact with this medicine
It is very important to inform your doctor about all medications you are taking, as some medications can react with Icosapent ethyl and cause unwanted effects.
This includes any vitamins, nutritional supplements, Ayurvedic medicines, and even traditional herbal remedies you take. Tell your doctor about all of these.
Below are some medications that are more likely to interact with this medicine.
| Drug category | Examples |
|---|---|
| Blood thinners | Medicines such as Warfarin, Apixaban, Dabigatran, Rivaroxaban, Enoxaparin. Icosapent ethyl can further increase the risk of bleeding. |
| Aspirin and similar drugs | Aspirin and other NSAID-type drugs taken as painkillers. |
| Beta-blockers | Medicines for high blood pressure and heart disease, such as Metoprolol and Propranolol. |
| Female hormones | Estrogen-containing medications and birth control pills. |
Things to keep in mind when taking medication
- Blood tests: Your doctor will likely order blood tests to check things like your triglyceride levels and liver function while you're on this medication. Don't skip them and get them done on time.
- Healthy Lifestyle: As we said before, this medicine is not a magic bullet. A healthy diet and daily exercise are essential. It is also good to include fish rich in omega-3 (salmon, mackerel, herring, sardines) in your diet.
- Before surgery: If you are having surgery or a tooth extraction, tell your doctor or dentist in advance that you are taking this medicine . You may need to stop taking this medicine a few days before the surgery.
What side effects might I experience?
Like any medicine, this one can cause side effects in some people. But most people don't. Let's take a look at what these side effects are, and which ones are serious.
| Classification of side effects | |
|---|---|
| If you experience these symptoms, tell your doctor immediately or go to the hospital. | |
| Allergic reactions | Skin rash, itching, swelling of the lips, tongue or face. |
| Difficulty breathing | Shortness of breath, feeling of tightness in the chest. |
| Abnormal bleeding | Unexplained bruising anywhere on the body, nosebleeds, and bleeding gums. |
| Fast or irregular heartbeat | Feeling like your heart is beating fast, feeling a fluttering in your chest. |
| These are usually not serious, but if they persist, tell your doctor. | |
| Muscle or joint pain | Pain in limbs and joints. |
| Constipation | Difficulty going to the toilet. |
| Swelling of the limbs | Swelling of the ankles, feet, or hands. |
| Gout | Joint swelling and severe pain. |
Take-Home Message
- Icosapent ethyl is a medication that lowers triglyceride levels, but it is not a substitute for a healthy diet and exercise.
- Always take this medicine with a meal . Swallow the capsule whole.
- Tell your doctor about all other medications , vitamins, and even Ayurvedic medicines you are taking.
- If you experience symptoms such as sudden allergic reactions, difficulty breathing, or unusual bleeding, seek medical advice immediately .
- Never stop taking medication or change the dosage without your doctor's advice.
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