Sometimes we get serious bacterial infections that ordinary antibiotics can't cure, right? In such cases, doctors decide to use a stronger medication that is injected directly into a vein. Today we're going to talk about one such very important vaccine, which is a combination of three medications.
What kind of medicine is this?
Simply put, this is a powerful antibiotic made from a combination of three drugs: Imipenem, Cilastatin, and Relebactam . In medicine, we refer to these as `(Carbapenem)` antibiotics. In the market, it can be found under the name `(RECARBRIO)`.
Its main function is to destroy certain types of harmful bacteria that have entered the body and cure infections caused by them.
It's important to remember that this medicine only works on bacterial infections . It won't cure viral infections like the common cold or flu. It's like trying to open a door with the wrong key.
Things you need to tell your doctor before taking medicine
Before starting this medication, it is essential to give your doctor a complete description of your health condition. In particular, you should tell them about the following:
| Your situation | Why is notification important? |
|---|---|
| A condition such as a brain tumor or seizures | This medication can sometimes increase the risk of seizures, so special care should be taken with it. |
| Kidney disease | This medicine is eliminated from the body mainly through the kidneys. If the kidneys are not functioning properly, the dose of the medicine may need to be adjusted. |
| Allergy to something | Be sure to tell us if you have any allergies to this medicine, other antibiotics, foods, or dyes. |
| Being pregnant or expecting a baby | Any medication should be used with extreme caution during pregnancy, so the doctor should be aware of this. |
| Breastfeeding the baby | Since parts of the medicine can pass to the baby through breast milk, it is important to talk to your doctor about it. |
How do you use this medicine?
This medicine is given through a vein (intravenous or IV infusion). This is usually done by a doctor or nurse in a hospital or clinic.
However, sometimes you may need to inject this medicine at home. If so, you will be taught how to prepare and inject it properly. It is very important to take the medicine exactly as prescribed, at the right time, and in the right dose. Do not stop taking the medicine unless your doctor tells you to.
What do you do with used needles?
This is also very important. Never throw used needles and syringes in the trash . They should be put in a special container that is designed to be removed. If you don't have one, ask your doctor how you can get one.
What if I take too much medicine?
If you think you have overdosed, call the National Poisons Information Centre at the Colombo National Hospital immediately. Alternatively, go to the Emergency Department (ETU) of the nearest hospital. The most important thing is to act quickly and not panic.
Can there be problems with other medications?
Yes, some medications can interact with this vaccine and cause problems (drug interactions). You should tell your doctor if you are taking any of the following medications, in particular:
- Birth control pills
- Ganciclovir `(Ganciclovir)`
- Valproic Acid
Special Note: If you are using birth control pills, they may be less effective while taking this antibiotic. Therefore, it is important to talk to your doctor about using another safe method of birth control during this time.
This list is not complete. Therefore, tell your doctor about all the medications you are taking (including vitamins and herbal remedies). Also, tell your doctor if you are using alcohol, tobacco, or other drugs.
Things to be careful about while taking the medicine
- If your symptoms do not improve, or if they get worse, tell your doctor right away.
- Severe skin reactions: This medicine can sometimes cause severe skin reactions. These can occur weeks after starting the medicine. If you have fever, body aches, and red or purple blisters, blisters, or peeling skin , it is an emergency. Also, if you have swelling of the face, lips, or a rash on your neck or armpits, call your doctor right away.
- Diarrhea: You may experience diarrhea while taking this medicine. However, if you have severe diarrhea that lasts for more than two days, do not take over-the-counter medications and talk to your doctor. This could be a sign of another infection.
What are the possible side effects?
Like any medication, this one can have some side effects. Let's break them down into two categories.
| Type of side effect | Characteristics |
|---|---|
| Things to report to your doctor immediately | |
| Allergic reactions | Skin rash, itching, swelling of the face, lips or tongue, difficulty breathing. |
| Severe diarrhea | Severe diarrhea with blood or water. |
| Other serious symptoms | Confusion, fever, seizures, skin redness, blistering, or peeling. |
| Symptoms of Anemia | Unusual tiredness, paleness, blue eyes, dizziness, difficulty breathing. |
| Things that are usually not serious, but should be reported to the doctor if they persist | |
| Minor injuries | Headache, nausea, vomiting, constipation, pain or redness at the injection site. |
This list does not include all possible side effects. If you notice anything unusual, talk to your doctor about it.
Take-Home Message
- This is a powerful antibiotic used only for bacterial infections. It is not given for the common cold.
- Before starting the medication, tell your doctor about all your medical conditions (especially kidney disease, seizures, allergies) and all other medications you are taking.
- Seek immediate medical attention if you experience a severe skin reaction, bloody diarrhea, or signs of an allergy.
- If you are using birth control pills, discuss additional birth control methods with your doctor during this treatment.
- Never share this medicine with others. Dispose of used needles and syringes safely in a sharps container.
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