Anyone who suffers from constipation knows how annoying and uncomfortable it is to have a bowel movement for days, a full stomach, and a stomachache. Sometimes this is not just constipation, but constipation that comes with a condition called Irritable Bowel Syndrome (IBS) . So, a special medicine that doctors recommend to control such conditions is Linaclotide. Today, we will talk about this medicine, how to use it, things to be careful about, and everything else.
What kind of medicine is Linaclotide?
Simply put, Linaclotide is a medicine that helps you pass stool more easily. It works by drawing more water into your intestines and using that water to soften your stool. This makes it easier for hard stool to pass through your intestines. This also reduces symptoms like abdominal pain and bloating.
This medicine is mainly used for:
- A condition called Irritable Bowel Syndrome with Constipation (IBS-C) .
- Chronic constipation caused by other causes.
Things you need to tell your doctor before using the medicine
Before prescribing Linaclotide to you, your doctor will ask you about certain things. It is very important for you to inform your doctor about these things as well.
| Situation you should be aware of | Why is that? |
|---|---|
| If you often have diarrhea | This medication can also cause diarrhea, so if you already have that condition, it can get worse. |
| If you have had a previous intestinal blockage or fecal impaction | Using this medicine in such a situation could be risky. |
| If you have allergies to linaclotide or other medicines or foods | It is essential to be aware of this to prevent an allergic reaction. |
| If you are pregnant, trying to get pregnant, or breastfeeding | You should discuss the safety of this medication with your doctor before making a decision during pregnancy and breastfeeding. |
How should I use this medicine?
It is very important to use this medicine exactly as the doctor says.
- Take this pill with a glass of water.
- Take it at the same time every day, at least 30 minutes before the first meal of the day, on an empty stomach .
- Swallow the tablet whole. Do not break, crush, or chew it.
- Continue using it until your doctor tells you to stop.
- This medicine is not approved for children , so talk to your doctor about it.
What if you take too much medicine? (Overdose)
If you think you have taken more of this medicine than prescribed, do not panic and immediately contact the National Poisons Information Centre at the Colombo National Hospital. Or go to the Emergency Department (ETU) of the nearest hospital.
This medicine has been prescribed for you only. Never give this medicine to anyone else, even if they have the same symptoms as you.
What if I miss a dose of medication?
Don't worry. If you miss a dose, forget it completely. Take the next dose at the scheduled time. Never take two doses at once to make up for a missed dose.
Things to consider when taking medication
While using this medicine, you need to be a little careful about some things.
- Diarrhea: This is a common side effect of this medication. It usually starts within two weeks of starting the medication. However, if you develop severe diarrhea , stop taking the medication and call your doctor immediately.
- Emergencies: Be very careful of these symptoms.
If you have unbearable, severe stomach pain, especially if it is accompanied by bright red blood or tarry stools, it may be an emergency. Stop taking the medicine immediately and call your doctor or go to the nearest hospital emergency department (ETU).
What are the possible side effects?
Like any medicine, this one can have some side effects, but not everyone gets them.
| Type of side effect | Symptoms |
|---|---|
| Side effects that require immediate medical attention | |
| Allergic Reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
| Digestive system problems | Bloating, gas, stomach pain, diarrhea |
How do you store and dispose of the medicine?
Storage
- Keep out of reach of children and pets .
- Store at room temperature (25°C / 77°F).
- Keep the medicine in the original bottle it came in. Close the bottle cap tightly.
- Most importantly: Never remove the small packet (moisture-absorbing packet / desiccant) inside the bottle. It absorbs moisture from the medicine and keeps it dry.
- Do not use expired medicine.
Removal
Ask your doctor how to properly dispose of unused and expired medications. Some medications are not suitable for disposal in the trash, so it is important to dispose of them responsibly.
Take-Home Message
- Linaclotide is a special medication for IBS with constipation and chronic constipation.
- Always take this medicine on an empty stomach, 30 minutes before the first meal of the day.
- If you experience severe diarrhea, severe stomach pain, bleeding, or black stools, seek medical advice immediately.
- Tell your doctor about all other medications you are taking (including vitamins and Ayurvedic medicines).
- This medicine is for you only. Never share it with anyone else.


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