Many of us are afraid when we hear the word cancer. But with the advancement of medicine today, there are many treatments that can cure cancer. Among these treatments, chemotherapy takes the lead. So today we are going to talk about a special medicine that can kill such cancer cells. That is Procarbazine.
What kind of medicine is Procarbazine?
Simply put, Procarbazine is a chemotherapy drug that controls the growth of cancer cells, or slows down their growth. It comes in the form of capsules.
This medicine is mainly used to treat a type of cancer called Hodgkin's disease . It is not usually given alone. Doctors usually prescribe it in combination with other cancer medicines. It can also be used for other conditions. Your doctor will explain this to you.
Things you need to tell your doctor before starting medication
This is very important. It is important for your doctor to be aware of your complete health status, which greatly affects the success of your treatment. Therefore, before starting this medication, be sure to tell your doctor if you have any of the conditions listed below.
- If you have any infections (especially viral infections like chickenpox and herpes).
- If you have kidney disease or liver disease .
- If you have been reported to have low levels of red blood cells, white blood cells, or platelets in your blood.
- If you are a smoker .
- If you have previously had an allergy to procarbazine or any other chemotherapy drug, other medicine, food, or dye.
- If you are pregnant , trying to get pregnant , or breastfeeding . This is very important!
How do you use this medicine?
The method of using this medicine is very simple.
- Take the dose prescribed by the doctor with a glass of water.
- Take your medicine at the right time and at the right intervals. Do not take more or less than the amount your doctor tells you to take.
- No matter how uncomfortable you feel, do not stop taking the medication without medical advice.
- If you are giving this medicine to children, you should talk to a pediatrician about it and follow their instructions exactly.
What to do if you take too much medicine?
If you think you have taken too much medicine, immediately call the National Poisons Information Centre at the Colombo National Hospital . Or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
What if I miss a dose of medication?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take two doses at the same time.
Interactions with Procarbazine
When taking this medication, it is very important to tell your doctor about all the medications you are taking, including vitamins and herbal remedies. Some medications, foods, and drinks can interact with this medication and cause dangerous side effects.
| Type | Examples and descriptions |
|---|---|
| Do not take these with Procarbazine. | |
| Alcohol and green tea | Avoid drinking any type of alcohol and green tea. |
| Some medications | MAOIs (a type of medicine used for depression), Linezolid, Isoniazid (a medicine used for tuberculosis), some medicines used for allergies, colds, migraines, and medicines used for mental illnesses. |
| Talk to your doctor about these things. | |
| Painkillers | Painkillers such as Tramadol, Meperidine, Pentazocine. |
| Anesthetic drugs | Medicine given to induce sleep or numb a specific area during surgery. |
| Other medications | Phenytoin (a medicine used to treat seizures ), Dextromethorphan (found in some cough medicines), and Vaccines. |
| Foods containing Tyramine | This is very important! We will talk about this in detail below. |
Things to be especially careful about while taking the medicine
Pay special attention to foods containing Tyramine!
While taking this medicine, you should completely avoid foods containing the chemical 'Tyramine' . Because the combination of these two can cause dangerous conditions such as severe headaches, sudden increases in blood pressure, and irregular heartbeat .
Foods high in tyramine: aged cheeses, smoked and cured meats and fish (sausages, salami), beer, wine (especially red wine), soy sauce, coffee, chocolate, cola drinks, bananas, avocados, overripe fruit. Ask your doctor or nutritionist for a complete list.
Protect yourself from infections
Chemotherapy reduces the body's immune system, which means it's less able to fight off disease.
- If you develop symptoms such as fever, body aches, sore throat, or cough, notify your doctor immediately . Do not self-medicate.
- Avoid crowded places and places where people with illnesses are as much as possible.
Be careful of bleeding.
This medicine can reduce the number of platelets in the blood. These are the cells that help blood clot when bleeding occurs.
- If you notice anything like unexplained bruising on your body, small red spots on your skin, black stools, or blood in your urine, tell your doctor immediately.
- Be careful when brushing and flossing your teeth. If you see a dentist, tell them that you are taking this medicine.
Other important points
- Drowsiness and dizziness: This medication may cause drowsiness and dizziness. Therefore, avoid activities that require alertness, such as driving or operating machinery.
- Smoking: Smoking while taking this medicine may increase your risk of developing lung cancer in the future. Therefore, it is best to quit smoking completely.
- Pregnancy: Do not become pregnant while taking this medicine. It can be very harmful to the baby in the womb. It can also affect sperm count in men, so talk to your doctor about this if you are thinking about having a child.
Side effects of the medicine
Like any medicine, Procarbazine can cause side effects. However, not everyone gets them. The important thing is to know what to look out for.
| If you experience these symptoms, notify your doctor immediately. | |
|---|---|
| Allergies | Skin rash, itching, swelling of the face, lips, tongue. |
| Symptoms of low blood cell count | Fever, chills , sore throat (signs of infection), easy bruising, black stools (signs of bleeding), extreme fatigue, fainting (signs of low red blood cells). |
| Nervous system problems | Confusion, hallucinations, difficulty walking or speaking, seizures , numbness or pain in the limbs, tremors. |
| Other serious symptoms | Difficulty breathing, vision changes, mouth sores, yellowing of the eyes or skin. |
| If these things persist or become bothersome, tell your doctor. | |
| Common side effects | Nausea, vomiting, loss of appetite, hair loss, dry mouth, headache, constipation or diarrhea (these are things to expect during chemotherapy). |
Take-Home Message
- Procarbazine is a powerful drug used to treat cancer. Therefore, take it exactly as your doctor tells you, at the right time .
- Inform your doctor about all other medications you are taking, even vitamins .
- Completely avoid foods containing tyramine (such as aged cheese, cured meats, wine).
- If you develop a fever, bruising, or other unusual symptoms, call your doctor immediately.
- Avoid becoming pregnant while taking this medicine. Talk to your doctor about this.
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