Sometimes it is difficult to take medicine by mouth due to severe vomiting, right? Even if you drink it, the medicine can come out again with vomiting. This rectal suppository is a special medicine that doctors prescribe in such cases. Today we are talking about this medicine called Prochlorperazine, which is used to control nausea and vomiting.
What kind of medicine is Prochlorperazine?
Simply put, Prochlorperazine is a medication that is used to control nausea and vomiting. It works by affecting the areas in our brain that control the signals that cause vomiting. It is available under brand names like Compazine and Compro.
When oral medication is not possible, we call this type of medicine that is inserted into the body through the rectum (rectal) a suppository . When it is placed in the rectum, it is quickly absorbed into the body through the blood vessels there. It can also be used for other things, so if you have questions about this medicine, ask your doctor.
Things to inform your doctor before taking the medicine
It is very important to inform your doctor about any other illnesses or health problems you have before prescribing this medicine. If you have any of the conditions below, be sure to tell them about it.
| Health condition or problem | Description |
|---|---|
| Brain and nervous system | Brain tumor, head injury, seizures, dementia, Parkinson's disease, muscle control problems. |
| Heart and blood circulation | Heart disease, irregular heartbeat, low blood pressure. |
| Other medical conditions | Diabetes, liver disease, glaucoma, lung or respiratory disease (e.g. asthma), intestinal obstruction, prostate problems. |
| Blood-related problems | Conditions such as low white blood cells, red blood cells, or platelets. |
| Habits and allergies | Frequent alcohol consumption, allergic reactions to Prochlorperazine or other medications, foods, or dyes. |
| Special occasions | If you are pregnant, trying to get pregnant, or breastfeeding. |
How exactly do I use this medicine?
This medicine is for rectal use only . Do not take it orally for any reason. Follow the steps below.
1. First, wash your hands thoroughly with soap. Wash your hands again after applying the medicine.
2. Carefully remove the silver foil wrapping around the pill.
3. Wet the tip of the pill with cold water. This will make it easier to insert.
4. Lie on your side. Keep your bottom leg straight and your top leg bent toward your stomach, near your knee.
5. Lift the upper buttock slightly to expose the rectum.
6. Now slowly insert the pill all the way into the rectum, pointed side first.
7. Press your buttocks together for a few seconds.
8. To prevent the medicine from coming out, wait for about 15 minutes .
9. Do not use more than the amount or frequency prescribed by your doctor.
When giving to children: Although this medicine is sometimes prescribed to children over 2 years of age, special care should be taken. Therefore, if you are giving this to a child, consult your doctor carefully and get advice.
What if I take too much medicine? (Overdose)
If you think you have taken more of this medicine than prescribed, immediately call the National Poisons Information Centre at the Colombo National Hospital , or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
What other medications may interact with this medicine?
Some medications may interact with Prochlorperazine, so it is important to inform your doctor about all medications you are taking.
| Medicines that should never be taken together | |
|---|---|
| Cisapride, Dofetilide, Dronedarone, Metoclopramide, Pimozide, Saquinavir, Thioridazine | |
| Other medications that may interact | |
| |
Important: This list may not include all medications, so be sure to tell your doctor about all medications you are taking, including herbs, vitamins, and traditional medicines.
Things to consider when taking the medicine
Drowsiness and driving
This medicine may make you feel drowsy and dizzy . It may also slow down your reaction time. Therefore, do not drive or operate machinery until you know how this medicine affects you. Get up slowly from a lying position. Drinking alcohol can increase these side effects.
Body temperature control
This medicine may affect your body's ability to regulate temperature. Your ability to tolerate extreme cold or extreme heat may be reduced.
- In cold weather: Stay indoors as much as possible. If you go outside, dress warmly.
- In hot weather: Avoid excessive exercise and sun exposure. Drink plenty of water. Wear loose, light-colored clothing.
Blood Sugar
This medicine may increase blood sugar levels. If you already have diabetes, you are at higher risk. Talk to your doctor about this and get advice.
Sun sensitivity
Your skin may be more sensitive to the sun while taking this medicine. So protect yourself from the sun. If you are going to be in the sun, wear clothing that covers your skin and use sunscreen.
What side effects might I experience?
Like any medicine, this one can have side effects. Some are serious, some are common.
| Side effects that you should report to your doctor immediately | |
|---|---|
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Neuroleptic Malignant Syndrome (NMS) | High fever, muscle stiffness, excessive sweating, fast or irregular heartbeat, and loss of consciousness. This is an emergency. |
| Extrapyramidal Symptoms (EPS) | Uncontrolled movements of body parts, muscle tightness or twitching, tremors, restlessness, dragging feet when walking. |
| Other serious symptoms | Dizziness, blurred vision, signs of infection (fever, chills, cough, sore throat) caused by low blood pressure, signs of increased Prolactin hormone (breast discharge, changes in monthly menstrual cycle). |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
| Drowsiness | Dizziness |
| Dry mouth | Constipation |
If your mouth is dry, things like chewing sugar-free gum and drinking lots of water can help.
Take-Home Message
- Prochlorperazine suppository is a medicine that is placed in the rectum for severe nausea and vomiting.
- Before taking this medicine, inform your doctor about all medical conditions you have and all other medications you are taking.
- Follow the correct method of using the medicine exactly. Wait at least 15 minutes.
- Seek immediate medical attention if you experience a serious side effect such as high fever, muscle stiffness, uncontrolled movements, or severe allergic reaction.
- This medication may cause drowsiness, so avoid driving until you know how it affects you.
- This is a medicine prescribed for you only. Never share it with others.
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