Have you ever noticed that your sperm has changed color, perhaps even turned yellow? Or have you faced some problems while expecting a child? Although many people do not like to talk about this openly, today we are talking about a condition called Pyospermia, which can be a cause of this condition. Don't worry, let's understand it simply.
Simply put, what is Pyospermia?
Pyospermia is an abnormally high number of white blood cells in your semen. It is sometimes called Leukocytospermia.
Now you might be thinking, "White blood cells are the good cells in our body that fight disease, so what happens when they increase?" Yes, that's true. White blood cells are like soldiers in our immune system. They fight against infections. But, as they say, too much of anything is not good, too many white blood cells in semen can cause problems.
Here's what happens: White blood cells produce powerful chemicals called Reactive Oxygen Species (ROS) to kill infections. But when there are too many of these in sperm, these chemicals called ROS start to damage healthy sperm as well.
- It damages the sperm membrane.
- It reduces sperm motility.
- It damages the DNA of sperm.
Generally, if there are more than one million white blood cells in 1 milliliter (1mL) of semen, it is considered a condition called Pyospermia.
Is this condition serious? Will it affect fertility?
This is the biggest problem that many people have. Yes, Pyospermia can affect your fertility. Because as we discussed earlier, excess white blood cells damage healthy sperm. When sperm are damaged, their ability to fertilize an egg decreases.
However, this does not affect everyone the same. Some people may have this condition without any symptoms (asymptomatic). In such cases, it is possible that the fetus may not be significantly affected. Therefore, to know exactly about this, it is best to see a doctor and get tested.
What are the symptoms of pyospermia?
Most people with this condition do not experience any symptoms. However, if the cause of pyospermia is an infection, you may experience some of the following symptoms:
| Symptom | Description |
|---|---|
| Fever | Increased body temperature. |
| Swelling | Swelling in the testicles or the surrounding area. |
| Pain during urination (Dysuria) | Burning or discomfort when urinating. |
| Yellowing of semen | The color of semen changes from white or light gray to yellow. |
Why is sperm yellow?
Normally, the color of sperm is white or light gray. When white blood cells attack infections, the color of sperm can turn yellow. Apart from that, there are other reasons.
- Infection: Some bacterial or other infection.
- Going for a long time without ejaculating: Not having sex or masturbating for a long time can cause the color of semen to change.
- Urine mixing: A small amount of urine is mixed with semen when it is ejaculated.
If you notice any changes in the color or other characteristics of your sperm, don't hesitate to talk to your doctor about it.
What are the causes of pyospermia?
There are a number of reasons why this condition can occur. Some are simple, while others require medical attention.
| Reason | A simple explanation |
|---|---|
| Reproductive and urinary tract infections | Bacterial infections like E.coli and Mycoplasma. |
| Sexually transmitted infections (STIs) | Diseases such as Herpes, Gonorrhea, and Chlamydia. |
| Inflammation | Inflammation of the urethra (urethritis) or inflammation of the prostate gland (prostatitis). |
| Varicoceles (varicoceles) | Swelling of the veins in the testicles. |
| Autoimmune diseases | The body's immune system attacking its own cells. |
| Lifestyle habits | Tobacco, cannabis use, and excessive alcohol consumption. |
| Not having sex for a while | Infrequent ejaculation. |
Is this a contagious disease?
Pyospermia itself is not contagious. However, if it is caused by a sexually transmitted infection (STI), the infection can be passed from you to your partner. Therefore, if an STI is identified as the cause, it is essential that you and your partner receive treatment. Otherwise, the infection can continue to spread between the two of you.
How does a doctor diagnose this?
When you see a doctor, he or she will first ask about your symptoms, medical history, and sexual health. Then, they will perform a physical exam and order several tests to confirm the condition.
- Semen Analysis: This is the most important test. A sample of your semen is taken, examined under a microscope, and the number of white blood cells in it is counted.
- Urinalysis: This test is done to check for urinary tract infections.
- Imaging Tests: Sometimes you may be asked to have an X-ray, CT scan, or MRI scan to get a clearer look at the inside of your reproductive and urinary systems.
What are the treatments for pyospermia?
Treatment depends on the cause. Sometimes, the condition may go away without any treatment.
Removing white blood cells from sperm improves sperm function and increases the chances of conception.
The usual treatments are:
- Antibiotics: If the cause is a bacterial infection, your doctor will prescribe antibiotics. It is very important to take the full course of medication as prescribed. Otherwise, the infection may come back.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): These drugs help reduce pain and swelling. They may also help improve sperm count.
With proper treatment, the prognosis for many people with pyospermia is good. It is often the case that the quality of life improves after treatment. Consult a healthcare provider. They can give you a better idea of what to expect.
With proper treatment, most men with pyospermia can recover well. Sperm quality often improves after treatment. Talk to your doctor to get a clear understanding of what you can expect.
Can pyospermia be prevented?
Although it cannot be completely prevented, there are several things you can do to reduce the risk.
- Practice safe sex: Using a condom can protect you from sexually transmitted infections.
- Make lifestyle changes: Avoid tobacco and marijuana use completely. If you drink alcohol, limit it.
- Get regular medical checkups: If you are sexually active, it is important to get regular STI tests.
When should I see a doctor?
If you experience any of the following, you should definitely see a doctor.
- If you and your partner have been trying for at least a year but have not conceived a child.
- If you have any of the symptoms mentioned earlier.
After seeing your doctor and starting treatment, be sure to go for follow-up tests regularly. If you take antibiotics, you may be asked to have another semen test in a few months.
Take-Home Message
- Pyospermia is an abnormal increase in the number of white blood cells in the semen.
- This condition can cause male infertility because it damages healthy sperm.
- Although symptoms are often absent, symptoms such as fever, urinary tract infection, and yellowing of semen may occur.
- If the cause is an infection, it can often be cured with treatment such as antibiotics.
- If you are having difficulty conceiving a child or have any symptoms, it is very important not to be shy and seek advice from a doctor.


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