Ke kuhikuhi ke kauka i kahi lāʻau lapaʻau hou no kekahi e hakakā nei me ka maʻi kanesa, he mea maʻamau ke manaʻo iki i ka hopohopo a me ka hoihoi. "He aha ka mea e hana ʻia me kēia?", "Pehea wau e hoʻohana ai i kēia?", "Aia kekahi mau hopena ʻaoʻao?" He nui paha kāu mau nīnau i loko o kou manaʻo. ʻO ia ke kumu e hele mai nei mākou e kamaʻilio e pili ana i ka lāʻau lapaʻau i kuhikuhi ʻia iā ʻoe, ʻo Crizotinib, ma ke ʻano maʻalahi a maʻalahi hoʻi e hoʻomaopopo. E noʻonoʻo i kēia me he mea lā e haʻi aku ana kahi hoaaloha a ʻohana paha iā ʻoe e pili ana i ia mea.
I ka'ōlelo maʻalahi, he aha ka Crizotinib?
He lāʻau lapaʻau kūikawā ʻo Crizotinib i hoʻohana ʻia e mālama i kekahi mau ʻano maʻi kanesa. Ma ko mākou ʻāina, ʻike pinepine ʻia kēia lāʻau lapaʻau ma lalo o ka inoa inoa ʻo XALKORI . He lāʻau lapaʻau kēia e hana ana e like me ka missile e kuʻi ana i kāna pahuhopu.
E noʻonoʻo i nā hunaola kanesa e like me nā mea kanu maikaʻi ʻole e ulu ana ma waho o ke kaohi. Aia kahi protein kūikawā e kōkua ana i kēia mau mea kanu maikaʻi ʻole e ulu a pālahalaha. Ua like ia me kahi paipu e hoʻolako ana i ka wai i kēlā mea kanu maikaʻi ʻole. ʻO kēia lāʻau i kapa ʻia ʻo Crizotinib e ālai ana i kēlā paipu, kēlā protein kūikawā. A laila ua emi ka hiki o nā hunaola kanesa ke ulu a pālahalaha ma ke kino holoʻokoʻa, a i ʻole e pau loa. Penei ke kōkua ʻana o kēia lāʻau i ka kaohi ʻana i ka maʻi kanesa.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau
He lāʻau ikaika loa ʻo Crizotinib, no laila he mea nui i kāu kauka ke loaʻa kahi kiʻi piha o kou olakino ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau. Mai hūnā i kekahi mea, ʻoiai nā kikoʻī liʻiliʻi loa. ʻO kēlā me kēia ʻike āu e kaʻana like ai e kōkua i kāu kauka e mālama palekana iā ʻoe.
ʻO kou palekana ka mea mua, no laila e kamaʻilio pono e pili ana i kēia ʻike me kāu kauka.
E nānā i ka papa ma lalo. Inā pili kekahi o kēia mau mea iā ʻoe, e hōʻoia e haʻi iā lākou.
| ʻAno ʻike | He aha kāu e haʻi aku ai i kāu kauka |
|---|---|
| Nā kūlana olakino o kēia manawa |
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| Nā maʻi ʻaleka | Inā loaʻa iā ʻoe kahi maʻi maʻi iā Crizotinib a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻomalu paha. |
| Ka hāpai ʻana a me ka hānai ʻana i ka waiū |
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Pehea e hoʻohana pono ai i ka lāʻau lapaʻau?
No ka loaʻa ʻana o ka hopena maikaʻi loa mai kēia lāʻau lapaʻau, he mea nui loa ia e hoʻohana pono.
- E ale wale: Loaʻa kēia lāʻau lapaʻau ma ke ʻano he capsule. Mai uhaʻi, kuʻi, a nau paha. E ale holoʻokoʻa me kahi aniani wai.
- I ka manawa: E hoʻomaʻamaʻa i ka lawe ʻana i kāu lāʻau lapaʻau i ka manawa like i kēlā me kēia lā. E lawe i ka nui kūpono, e like me ka ʻōlelo a kāu kauka iā ʻoe.
- Me ka ʻai a me ka ʻole o ka meaʻai: Hiki ke lawe ʻia kēia lāʻau lapaʻau ma mua a ma hope paha o ka ʻai. Eia nō naʻe, hiki i kekahi poʻe ke ʻeha iki i ka ʻōpū a i ʻole ka luaʻi i ka wā e lawe ai me ka ʻole o ka meaʻai. Inā hana ʻia kēia, e lawe i ka lāʻau lapaʻau me kekahi meaʻai.
- Mai lawe pū me ka wai pomelo: He mea nui loa kēia. E pale i ka lawe ʻana i kēia lāʻau lapaʻau me ka wai pomelo a i ʻole ka wai pomelo. ʻO kēia no ka mea hiki i nā mea hana i loko o ka wai pomelo ke hoʻololi i ke ʻano o ka omo ʻana o ka lāʻau lapaʻau e ke kino a hoʻonui i nā hopena ʻaoʻao.
- Inā ʻoe e luaʻi: Inā ʻoe e luaʻi ma hope o ka lawe ʻana i ka lāʻau lapaʻau, mai lawe hou i kahi lāʻau ʻē aʻe. E hōʻalo i kēlā manawa a lawe i kāu lāʻau aʻe i ka manawa i hoʻonohonoho ʻia.
- Inā ʻoe e poina i kahi lāʻau:
- Inā ʻoi aku ma mua o 6 mau hola a hiki i kāu mahele aʻe, e lawe i ka mahele i hala i ka wā e hoʻomanaʻo ai ʻoe.
- Eia nō naʻe, inā ʻaʻole i hala ma mua o 6 mau hola a hiki i kāu mahele lāʻau aʻe, e kāpae i ka mahele lāʻau i hala. E lawe i kāu mahele lāʻau aʻe i ka manawa i hoʻonohonoho ʻia. Mai lawe i ʻelua mau mahele lāʻau i ka manawa hoʻokahi.
- Mai ho'ōki i ka lawe ʻana i ka lāʻau lapaʻau: ʻOiai inā loaʻa iā ʻoe nā hopena ʻaoʻao a i ʻole no kekahi kumu ʻē aʻe, mai hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau a hoʻololi paha i ka dosage me ka ʻole o ke aʻo ʻana a kāu kauka.
Overdose
Inā loaʻa iā ʻoe kekahi kānalua ua lawe hewa ʻoe i nā lāʻau lapaʻau ma mua o kou manaʻo, e hele koke i ka Halemai Pilikia (ETU) kokoke loa. A i ʻole e kelepona i ke Kikowaena ʻIke Lāʻau Lapaʻau Lahui ma ka Halemai Lahui ʻo Colombo no ka ʻōlelo aʻoaʻo.
Nā mea ʻē aʻe e launa pū me kēia lāʻau lapaʻau (Nā Hana like ʻana)
Hiki i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei ke launa pū me Crizotinib a hoʻoulu i nā hopena makemake ʻole. No laila, he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (nā lāʻau lapaʻau no nā maʻi ʻē aʻe, nā huaora, nā mea hoʻopihapiha meaʻai, nā lāʻau Sinhala, nā lāʻau Ayurvedic).
E makaʻala loa i ka hiki ʻana o Crizotinib ke launa pū me nā lāʻau lapaʻau e hiki mai ana.
| Nā lāʻau lapaʻau ʻaʻole pono e lawe pū ʻia me Crizotinib | |
|---|---|
| ʻO kekahi mau lāʻau lapaʻau no nā maʻi fungal | E like me: Ketoconazole, Itraconazole, Fluconazole, Posaconazole |
| Nā lāʻau lapaʻau kūikawā ʻē aʻe | Nā lāʻau lapaʻau e like me Dronedarone, Pimozide, Thioridazine, Saquinavir, Flibanserin, Levoketoconazole, Lomitapide, Lonafarnib, Pacritinib. |
| Nā lāʻau lapaʻau a me nā mea ʻē aʻe e hiki ai ke hoʻopilikia i nā hakakā | |
| Wai ʻAlani | Hiki paha i kēia ke hoʻololi i ke ʻano o ka hana ʻana o ka lāʻau lapaʻau. |
| Nā lāʻau hoʻohaʻahaʻa i ka helu o ka puʻuwai | E like me: Digoxin, Metoprolol, Propranolol, Diltiazem, Clonidine |
| Nā lāʻau ʻē aʻe e hoʻopilikia ai i ka ʻōpū o ka puʻuwai | E nīnau i kāu kauka e pili ana i kēia. |
Nā mea e pono ai ʻoe e makaʻala i ka wā e lawe ana i ka lāʻau lapaʻau
He mea nui loa ia e mālama pono i kou kino i ka wā o ka mālama ʻana.
Nā hoʻokolohua lapaʻau maʻamau
E nānā pinepine kāu kauka iā ʻoe a e hoʻonohonoho i nā hoʻokolohua koko. E hōʻoia e hele pinepine i kēia mau mea. E kōkua kēia mau hoʻokolohua i kāu kauka e ʻike pehea e pili ai ka lāʻau i kou kino a pehea e hana ai kou akepaʻa.
E mālama i kou ʻike maka.
Hiki i kekahi poʻe e lawe ana i kēia lāʻau lapaʻau ke ʻike i nā loli i ko lākou ʻike. Eia kekahi laʻana, ka ʻike maka pōwehiwehi, ka ʻike ʻana i nā halo a puni nā kukui, a me ka manaʻo e ʻike koke ʻia a nalowale nā kukui. Inā ʻike ʻoe i kekahi o kēia mau loli i kou ʻike, e haʻi koke i kāu kauka.
E pale iā ʻoe iho mai nā maʻi
Hiki i nā lāʻau lapaʻau kanesa e like me Crizotinib ke hoʻonāwaliwali iki i ka ʻōnaehana pale o kou kino, ʻo ia hoʻi, ʻoi aku ka nui o kou maʻi, ʻoiai nā maʻi.
- Inā loaʻa iā ʻoe nā hōʻailona e like me ke kuni, ke anu, ka ʻāʻī ʻeha, a i ʻole ke kuni , mai hoʻōla ponoʻī. E kelepona koke i kāu kauka.
- E hōʻalo i nā wahi i piha ai ka poʻe maʻi a me nā wahi e hiki ai i ka poʻe maʻi.
- E holoi pinepine i kou mau lima me ke kopa.
- Ke loaʻa iā ʻoe ke kuni, mai lawe i nā lāʻau lapaʻau e like me Aspirin, Ibuprofen, a i ʻole Panadol (Acetaminophen) me ka ʻole o ke kūkākūkā ʻana me kāu kauka e hoʻēmi iā ia. Hiki i kēia mau mea ke kāohi i ke kuni a pale i ke kino mai ka ʻike ʻana i kahi maʻi.
E pale iā ʻoe iho mai ka lā.
Hiki i kou ʻili ke lilo i mea ʻoi aku ka maʻalahi i ka lā i ka wā e lawe ana i kēia lāʻau lapaʻau. No laila,
- E pale i ka hele ʻana i waho i ka lā i ka hiki.
- Inā ʻoe e hele i waho, e ʻaʻahu i nā lole e uhi pono ana i kou kino a e ʻaʻahu i ka pāpale.
- E nīnau i kāu kauka a hoʻohana i kahi pale lā maikaʻi.
Ka hāpai ʻana, ka hānai ʻana i ka waiū a me ka hānau keiki ʻana
He mea nui loa kēia manaʻo.
- I ka wā hāpai: Pono ʻoe e pale i ka hāpai ʻana i ka wā e lawe ana i kēia lāʻau lapaʻau a i ʻole no 45 mau lā ma hope o ka hoʻōki ʻana i ka lāʻau. Hiki i kēia lāʻau lapaʻau ke hana i nā kīnā hānau koʻikoʻi i kahi pēpē i hānau ʻole ʻia. Pono ʻoe e loaʻa i kahi hoʻāʻo hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau e hōʻoia ʻaʻole ʻoe e hāpai.
- No nā kāne: Inā ʻoe e lawe ana iā Crizotinib a he hiki i kāu hoa ke hānau keiki, e hoʻomaopopo pono e hoʻohana i ka condom i ka wā o ka moekolohe i ka wā o ka lāʻau lapaʻau a no nā lā 90 ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.
- Ka hānai waiū ʻana: Mai hānai waiū i kāu pēpē i ka wā o ka lāʻau lapaʻau a no 45 mau lā ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.
- Ka hānau keiki ʻana:Hiki i kēia lāʻau lapaʻau ke hoʻopilikia i ka hānau keiki (hiki ke loaʻa nā keiki) i nā wahine a me nā kāne. Inā he mau hopohopo kāu e pili ana i kēia, e kamaʻilio me kāu kauka e pili ana i ia mea ma mua o ka hoʻomaka ʻana i ka lāʻau.
Nā hopena ʻaoʻao e hiki mai ana ma muli o kēia lāʻau lapaʻau
E like me nā lāʻau lapaʻau a pau, hiki iā Crizotinib ke hana i nā hopena ʻaoʻao. Eia naʻe, ʻaʻole loaʻa i nā kānaka a pau. He mea liʻiliʻi kekahi. Akā aia kekahi mau mea e pono ʻoe e makaʻala koke.
| Nā hopena ʻaoʻao e pono ʻoe e hōʻike koke i kāu kauka | |
|---|---|
| Nā hopena alerika | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe, ke alelo a i ʻole ka puʻu. |
| Nā loli i ka helu o ka puʻuwai | Manaʻo e like me ka wikiwiki o ka puʻuwai a i ʻole ke kuʻi ʻano ʻole, ka poniuniu, ka nāwaliwali, ka ʻeha o ka umauma, a me ka paʻakikī o ka hanu ʻana. |
| Ua emi ka helu o ka puʻuwai | Ka poniuniu, ka māʻule ʻana, ka huikau, ka paʻakikī o ka hanu ʻana, a me ka manaʻo luhi ʻē. |
| Nā hōʻailona o ka hōʻino ʻana o ke akepaʻa | ʻEha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, nalowale ka makemake e ʻai, nausea, nā ʻōpala māmā, mimi melemele ʻeleʻele a ʻeleʻele paha, melemele o ka ʻili a i ʻole nā maka, luhi ʻē. |
| Nā pilikia e pili ana i ka māmā | ʻO ka ʻū maloʻo i wehewehe ʻole ʻia, ka paʻakikī o ka hanu ʻana, ka pōkole o ka hanu. |
| Nā hōʻailona o ka maʻi | Kuni, anu, ʻū, ʻeha ka puʻu, nā ʻeha ʻaʻole e ho'ōla, ʻeha i ka wā e mimi ai. |
| Nā hōʻailona koʻikoʻi ʻē aʻe | Nā loli o ka ʻike, nā ʻeha waha a ʻāʻī paha, ka maʻi pākī nui a mau paha, ka ʻike i ka mālamalama. |
| Nā hopena ʻaoʻao e pono e hōʻike ʻia i ke kauka inā hoʻomau lākou a hoʻopilikia paha | |
| Nā hopena ʻaoʻao maʻamau |
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Leka Lawe-Home
- He lāʻau lapaʻau maʻi kanesa ʻo Crizotinib. Pono e lawe ʻia e like me ka ʻōlelo a kāu kauka.
- E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei (me nā lāʻau lapaʻau kūʻai ʻole ʻia). Mai lawe i kēia lāʻau lapaʻau me ka wai pomelo.
- Inā loaʻa iā ʻoe kekahi mau hopena koʻikoʻi e like me nā loli i ka ʻike, ka paʻakikī o ka hanu ʻana, nā loli i ka helu o ka puʻuwai, a i ʻole ke kuni , e hoʻomaopopo koke i kāu kauka.
- Mai ho'ōki i ka lawe ʻana i ka lāʻau lapaʻau a hoʻololi paha i ka dosage me ka ʻole o ke aʻo ʻana a kāu kauka.
- Mai hāpai loa i ka wā e lawe ana i kēia lāʻau lapaʻau a no ka manawa i kuhikuhi ʻia. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana palekana no ka hoʻomalu hānau.
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