ʻO ka moeʻuhane e lilo i makuahine a makua paha ka manaʻolana nui loa i loko o ka puʻuwai o kēlā me kēia kanaka. Akā i kekahi manawa, ma muli o nā kumu like ʻole, ua keakea ʻia kēlā moeʻuhane. ʻO ka paʻakikī i ka hāpai ʻana i kahi keiki, a i ʻole ka hānau ʻole ʻana, he pilikia ia e kū nei i nā kānaka he nui i loko o ke kaiāulu i kēia lā. No laila, i ka manawa e like me kēia, he nui nā ʻano hana e hiki ai ke hoʻokō i kēlā moeʻuhane me ke kōkua o ka lāʻau lapaʻau hou. I kēia lā, e kamaʻilio mākou e pili ana i kekahi ʻano lapaʻau holomua loa. ʻO ia ka ʻenehana i kapa ʻia ʻo ICSI (Intracytoplasmic Sperm Injection).
I ka ʻōlelo maʻalahi, he aha ka ICSI?
ʻO ka inoa lōʻihi ʻo ICSI paha ke kani iki nei he paʻakikī. Akā, he maʻalahi loa kona manaʻo. ʻO ICSI (Intracytoplasmic Sperm Injection) kahi ʻano hana kūikawā i hoʻohana ʻia no ka mālama ʻana i ka hānau ʻole ʻana, i hana ʻia ma kahi keʻena hoʻokolohua. Maanei, hoʻokomo pono ʻia kahi sperm hoʻokahi, olakino, a koho maikaʻi ʻia i loko o kekahi o nā hua o ka makuahine . ʻO ka pahuhopu nui o kēia ʻano hana, ʻo ia ka hana ʻana i kahi embryo ma o ka hoʻoulu ʻana iā ia me ke ʻano hana.
Ua lohe paha ʻoe i ka IVF (In Vitro Fertilization). ʻO ICSI kekahi ʻanuʻu holomua a kūikawā hoʻi i ka mālama ʻana i ka IVF. He mea kōkua nui kēia ʻano hana no ka poʻe i nalowale kā lākou mau keiki ma muli o ka hānau ʻole ʻana o ke kāne.
He aha ka manaʻo o ka huaʻōlelo intracytoplasmic?
He ʻano ʻepekema kēia. I ka ʻōlelo maʻalahi, aia kahi mea e like me ka jelly i loko o kahi hua manu. Kāhea mākou iā ia he cytoplasm. ʻO Intracytoplasmic ke ʻano "i loko o ka cytoplasm." ʻO ia hoʻi, ua hoʻokomo ʻia ka sperm i loko o kēia ʻāpana o ka hua manu i kapa ʻia ʻo cytoplasm.
He aha ka ʻokoʻa ma waena o ICSI a me IVF maʻamau?
He nīnau kēia a ka poʻe he nui. ʻOiai ʻo ICSI kekahi ʻāpana o ke kaʻina hana IVF, aia kahi ʻokoʻa iki ma waena o nā mea ʻelua. E noʻonoʻo e pili ana i kēia ʻano.
- ʻAno IVF kuʻuna: Ma kēia, ua waiho ʻia ka hua manu i lawe ʻia mai ka makuahine i loko o kahi kīʻaha lab kūikawā a ua kau ʻia nā tausani o ka sperm mai ka makuakāne a puni. A laila, hele hoʻokahi kekahi o kēlā mau sperm, hou i ka hua manu, komo i loko, a kali no ka hoʻoulu ʻana. ʻO ia hoʻi, ua ʻae ʻia kēia e hana maoli. I kekahi manawa, ʻaʻole hiki i hoʻokahi sperm ke komo i loko o ka hua manu.
- ʻAno ICSI: ʻAʻole kēia ka hihia ma ʻaneʻi. Maanei, ua koho ʻia ka sperm maikaʻi loa a olakino loa a hoʻokomo pololei ʻia i loko o ka hua manu. Ua like ia me kahi lawelawe lawe kūikawā. Hoʻonui kēia i nā manawa kūpono o ka hoʻoulu ʻana.
ʻO ka mea nui, ʻoiai ʻo ke ʻano o kēia mau ʻano ʻelua i hoʻohana ʻia e hana i ka embryo, ʻo ka hana aʻe, ʻo ke kaʻina hana o ke kanu ʻana i ka embryo i loko o ka ʻōpū o ka makuahine (hoʻoili embryo), ua like ia no nā mea ʻelua.
Ua kapa ʻia ʻo ICSI a me IVF ʻo Assisted Reproductive Technology (ART).ʻO ia hoʻi, he ʻano hana e kōkua ai i ka hāpai ʻana i kahi keiki ma o ka hoʻohui ʻana i nā hua a me ka sperm ma waho o ke kino, ma kahi keʻena hoʻokolohua.
No wai ka lāʻau ICSI kūpono loa?
Ua paipai kūikawā ʻia ʻo ICSI no nā kāne me nā pilikia hānau ʻole o ke kāne . Aia ma lalo iho kekahi o nā kūlana e hiki ai i kāu kauka ke kuhikuhi i kēia lāʻau lapaʻau.
| Pilikia/kūlana | He wehewehe maʻalahi |
|---|---|
| Hoʻoheheʻe ʻana | ʻO ka nele o ka ejaculation i ka wā o ka moekolohe a i ʻole ka masturbation. |
| He haʻahaʻa ka helu sperm | Haʻahaʻa loa ka helu sperm i loko o ka semen. |
| ʻAno maikaʻi ʻole o ka sperm | Ka hoʻopilikia ʻana i ke ʻano o ka sperm a i ʻole ka neʻe ʻana (hiki ke ʻauʻau). |
| Ka ejaculation retrograde | ʻAʻole puka mai ka sperm a kahe i hope i ka ʻōpū mimi. |
| Nā maʻi ʻōnaehana hānau | Aia kekahi mea keakea i ke ala o ka sperm. |
Eia kekahi, hiki ke hoʻohana pono ʻia ke ʻano ICSI i kekahi mau hihia ʻē aʻe:
- I nā hihia kahi i hoʻāʻo mua ʻia ai ka mālama IVF maʻamau akā ʻaʻohe embryo i hana ʻia .
- Inā ʻoi aku ka nui o ka wahine nāna i hāʻawi i nā hua ma mua o 35 mau makahiki .
- Nā hua manu a i ʻole sperm i hoʻopaʻahau mua ʻia no ka mālama ʻana (cryopreservation)Inā hoʻohana ʻia.
Pehea e hana ai ke kaʻina hana o ka mālama ʻana o ICSI?
Aia kēia kaʻina hana i kekahi mau ʻanuʻu koʻikoʻi, a hana ʻia nā mea a pau ma lalo o ka mākaʻikaʻi piha a kāu kauka a me kahi hui o nā loea.
1. Hoʻomākaukau ma mua o ka mālama ʻana: ka loaʻa ʻana o ka hua manu a me ka sperm
Ma mua o ka hana ʻana i ka ICSI, pono ʻoe e kiʻi i nā hua mai ka makuahine a me ka sperm mai ka makuakāne.
Pehea e loaʻa ai nā hua manu:
- Hoʻoulu ʻana i ka ovulation: ʻO ka maʻamau, hoʻokahi wale nō hua manu e hoʻokuʻu ʻia i kēlā me kēia mahina. Eia nō naʻe, no ka hoʻonui ʻana i ka holomua o kēia lāʻau lapaʻau, pono e kiʻi ʻia nā hua he nui i ka manawa hoʻokahi. No kēia, hāʻawi ʻia ka wahine i kekahi mau inikini hormone ma luna o 8 a 14 mau lā. Hoʻoulu kēia i nā ovaries a hoʻoulu i nā hua he nui e oʻo i ka manawa hoʻokahi.
- Ka lawe ʻana i nā hua: Ma hope o ka oʻo ʻana o nā hua, hoʻokomo ʻia kahi nila lahilahi loa ma o ka vagina ma lalo o kahi anesthetic māmā a i loko o nā ovaries. Hoʻohana ke kauka i ka ultrasound transvaginal e alakaʻi i ka lawe ʻana. Wehe pono ʻia nā hua mai ke kino me ka hoʻohana ʻana i kahi mea i hoʻopili ʻia i ka nila. ʻAʻohe ʻeha o kēia.
Pehea e loaʻa ai ka sperm:
ʻO ka maʻamau, hōʻiliʻili ʻia ka sperm i ka lā hoʻokahi e hōʻiliʻili ʻia ai nā hua.
- Pono ʻoe e hōʻole i ka moekolohe a i ʻole ka masturbation no ʻelua a ʻekolu mau lā ma mua o ka hāʻawi ʻana i ka sperm.
- Pono ʻoe e masturbate i loko o kahi lumi pilikino a hōʻiliʻili i kāu sperm i loko o kahi pahu kūikawā i hāʻawi ʻia e ka lab.
- Pono e hāʻawi ʻia kēia hāpana i ka hale hana i loko o hoʻokahi hola.
I kekahi mau hihia (e.g., ka hiki ʻole ke ejaculate, ke ālai ʻia ʻana o nā ducts sperm), pono ke kiʻi pololei ʻia ka sperm mai nā testicles ma ke ʻoki kino.
2. Ma ka lab: Ke kaʻina hana ICSI
ʻO kēia ka manawa koʻikoʻi. Ma hope o ka loaʻa ʻana o nā hua a me ka sperm, hana nā loea i ke kaʻina hana ICSI ma ka hale hana.
1. Hoʻopaʻa ʻia kahi hua manu i pala maikaʻi ʻia me kahi pipette aniani maikaʻi loa.
2. Ma lalo o kahi microscope mana kiʻekiʻe, ua koho ʻia kahi sperm hoʻokahi me ka neʻe olakino a maikaʻi loa .
3. Lawe ʻia ka sperm i koho ʻia me kahi nila lahilahi ʻē aʻe, hou ʻia ma ka paia o ka hua manu, a hoʻokomo ʻia i loko o ka cytoplasm .
4. A laila e wehe pono i ka nila.
3. Ma hope o ke kaʻina hana: Ka ulu ʻana o ka embryo a me ke kanu ʻana
Ma hope o ka hoʻokomo ʻia ʻana o ka sperm, e nānā pono ʻia ka hua manu ma ka hale hana no kekahi mau lā e ʻike ai inā ua hoʻomoe ʻia a lilo i embryo.
- Māhele kahi hua manu i hoʻopōmaikaʻi ʻia i loko o nā pūnaewele a ulu i kahi kahua i kapa ʻia he blastocyst ma hope o 5 a 6 mau lā.
- I kēia manawa, ua koho ʻia ka embryo olakino loa a ulu nui loa a hoʻokomo ʻia i loko o ka ʻōpū o ka makuahine. Ua kapa ʻia kēia he embryo transfer .
- No kēia kumu, me ka hoʻohana ʻana i ka ʻenehana ultrasound, ua hoʻokomo ʻia kahi ʻōmole lahilahi loa i kapa ʻia he catheter i loko o ka ʻōpū ma o ka vagina, a ua hoʻokomo ʻia ka embryo i loko o ka ʻōpū.
- I mea e hāpai ai, pono kēia embryo e hoʻopili pono iā ia iho i ka paia o ka ʻōpū a hoʻomaka e ulu ma laila.
ʻO ka maʻamau, ʻōlelo aʻo nā kauka ʻaʻole e lawe i kahi hoʻāʻo hāpai a hiki i ʻelua pule ma hope o ka hoʻoili ʻana o ka embryo. Hiki i kēia ke lilo i manawa hopohopo iki, akā he mea nui e hoʻomanawanui.
He aha nā pōmaikaʻi a me nā pilikia o ka mālama ʻana iā ICSI?
E like me nā lāʻau lapaʻau a pau, loaʻa iā ICSI nā pono a me kekahi mau pilikia.
Nā Pōmaikaʻi
ʻO ka pōmaikaʻi nui o kēia ʻano hana, ʻoi aku ka holomua ma mua o ka IVF kuʻuna i ka lanakila ʻana i nā pilikia hānau ʻole o ke kāne a me ka hāʻawi ʻana i nā mākua i ka manawa kūpono e loaʻa ai nā keiki. Ma kekahi mau kikowaena lapaʻau, hoʻohana ʻia ʻo ICSI no nā mea āpau, me ka nānā ʻole i ke kumu o ka hānau ʻole ʻana, ma muli o kona kiʻekiʻe o ka holomua.
Nā Pōʻino
| ʻAno pilikia | Wehewehena |
|---|---|
| Ka hōʻino ʻana i nā ovaries | He wahi liʻiliʻi loa ka manawa e hōʻino ʻia ai kekahi mau hua manu ke hoʻokomo ʻia ke kui. |
| ʻAʻole hana ka hoʻoulu ʻana. | ʻOiai inā hoʻokomo ʻia ka sperm, aia kahi manawa kūpono ʻaʻole e hoʻomoe ʻia ka hua manu a ʻaʻole e ulu aʻe i loko o kahi embryo. |
| Ka hoʻōki ʻana o ka ulu ʻana o ka pēpē | I kekahi manawa hiki i ka embryo ke oki i ka ulu ʻana ma hope o ke kanu ʻia ʻana i loko o ka lab a i ʻole i loko o ka uterus. |
Nā pilikia hiki ke loaʻa i ke keiki
He mea hopohopo kēia no nā mākua he nui. Ma kahi o 2% o nā keiki i hāpai ʻia ma ke ʻano kūlohelohe e loaʻa paha kekahi pilikia olakino (nā kūlana hānau) i ka wā hānau. Hōʻike kekahi mau noiʻi e piʻi iki kēia pilikia ma ka 1% wale nō, a i ʻole a hiki i ka 3%, no nā keiki i hāpai ʻia ma o ICSI.
Akā, manaʻoʻiʻo nā loea lapaʻau ʻo ke kumu o kēia hoʻonui ʻana paha ke kumu nui o ka hānau ʻole ʻana , ʻaʻole ka lāʻau ponoʻī. Eia nō naʻe, he mea nui e hoʻomaopopo he liʻiliʻi loa kēia pilikia.
Aia kekahi mau pilikia e hiki ke hoʻonui iki ʻia e ke ʻano ICSI:
- ʻO ka maʻi Angelman
- ʻAutism
- ʻO ka maʻi Beckwith-Wiedemann
- Nā maʻi o ka hoʻokaʻawale ʻana o ke kāne
- Nā Hypospadias
- Nā kīnā noʻonoʻo
Inā he kānalua a makaʻu paha kāu e pili ana i kēia, e kamaʻilio ākea me kāu kauka . E wehewehe hou aku ʻo ia i kēia iā ʻoe.
Āhea ʻoe e ʻike ai i ke kauka?
Inā ʻike ʻoe i kekahi o nā hōʻailona ma hope o ka mālama ʻana iā ICSI, e kāhea koke aku i kāu kauka.
- Nā hōʻailona o ka hāpai ʻana o ka ectopic: Nā hōʻailona o kahi embryo e hoʻokomo ʻia ana ma waho o ka ʻōpū (e.g., i loko o kahi ʻōmole fallopian) (e like me ka ʻeha nui ma kekahi ʻaoʻao o ka ʻōpū, ke kahe ʻana o ke koko ma ka vaginal).
- Nā hōʻailona o ka maʻi: ke kuni, ke anu, a me ka nui o ke kahe ʻana o ka ʻōpū.
- Nā hōʻailona o ka hāʻule ʻana o ke keiki: Ke kahe koko nui, ʻeha nui o ka ʻōpū.
- Nā hōʻailona o ka hānau mua ʻana: ʻO nā ʻūlū o ka ʻōpū e kū mai ana ma mua o ka lā hānau.
Ua kiʻekiʻe aʻe ka pilikia o ka loaʻa ʻana o nā māhoe?
I mea e hoʻonui ai i ka holomua o kāu hāpai ʻana, hiki i nā kauka ke hoʻoholo e hoʻoili i nā embryo he nui (e.g., ʻelua) i kou ʻōpū. Inā hana ʻia kēia, loaʻa paha iā ʻoe nā māhoe a i ʻole nā triplets. ʻO ka hāpai ʻana i nā keiki he nui e hoʻonui i ka pilikia o nā pilikia no ka makuahine a me ke pēpē, e like me ka hānau mua ʻana. No laila, he mea nui e kūkākūkā i ka nui o nā embryos e hoʻoili me kāu kauka.
Leka Lawe-Home
- ʻO ICSI kahi ʻano hana kūikawā o ka ʻenehana IVF e mālama ai i ka hānau ʻole.
- Maanei, hoʻokomo pololei ʻia kahi sperm hoʻokahi i koho ʻia i loko o ka hua manu a hoʻomoʻa ʻia.
- He hopena kūpono loa kēia ʻano hana, ʻoiai no nā pilikia e pili ana i ka hānau ʻole ʻana o nā kāne .
- He hana kēia i loaʻa i kekahi mau ʻanuʻu: ke kiʻi ʻana i nā hua a me ka sperm, ka hoʻoulu ʻana iā lākou i loko o ka lab, a me ke kanu ʻana i ka embryo i loko o ka uterus.
- E like me nā lāʻau lapaʻau āpau, aia kekahi mau pilikia liʻiliʻi. E hōʻoia e kūkākūkā ākea i kēia mau mea me kāu kauka a loaʻa kahi ʻike maopopo.
- He hoʻomaikaʻi ʻo ICSI o ka lāʻau lapaʻau hou e lawe mai ana i ka manaʻolana iā ʻoukou e hoʻāʻo nei e loaʻa kahi keiki. E kiʻi i ka ʻike pololei e pili ana i kēia a e hoʻomau ma lalo o ke alakaʻi ʻana a ke kauka kūpono.
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