E aʻo kākou e pili ana i ka lāʻau lapaʻau no ka maʻi Alzheimer

Ke lohe kākou ua loaʻa i ko kākou makuahine, makuakāne, a i ʻole kekahi mea kokoke loa iā kākou ka maʻi ʻo Alzheimer, nui ko kākou kaumaha a me ka hopohopo. He mea paʻakikī loa ka ʻike ʻana i ko lākou hoʻomanaʻo e nalowale mālie ana a poina iā lākou nā mea. Akā, mai hopohopo. ʻOiai ʻaʻohe lāʻau lapaʻau no kēia maʻi, aia kekahi mau ʻano lāʻau lapaʻau e hiki ke kōkua i ka kaohi ʻana i nā hōʻailona, ​​​​e hoʻolohi i ka holomua o ka maʻi, a e maʻalahi iki i ko lākou ola. I kēia lā, e kamaʻilio kākou e pili ana i kēlā mau lāʻau lapaʻau.

He aha ka mea e hana ʻia i ka lolo i ka maʻi o Alzheimer?

Ma mua o ko kākou kamaʻilio ʻana e pili ana i kēia lāʻau lapaʻau, e hoʻomaopopo maʻalahi kākou i ka mea e hana ʻia ana i ka lolo i ka maʻi Alzheimer. Hoʻololi ʻia nā leka ma waena o nā hunaola nerve i loko o ko kākou lolo ma o nā kemika. I ka maʻi Alzheimer, hoʻomaka nā protein ʻano ʻē (amyloid a me tau) e hōʻiliʻili i loko o ka lolo. Hoʻopōʻino kēia i nā hunaola nerve a hoʻopilikia i ke kamaʻilio ʻana ma waena o lākou. He hopena nui kēia i nā ʻāpana o ka lolo e kaohi ana i ka hoʻomanaʻo, ka noʻonoʻo ʻana, a me ke ʻano .

ʻO nā lāʻau lapaʻau o kēia manawa ke kāohi nui i kēia kaʻina hana. Hoʻoponopono kekahi mau lāʻau lapaʻau i nā pae o nā ʻelele kemika i loko o ka lolo, ʻoiai nā lāʻau lapaʻau hou e hoʻāʻo nei e wehe i nā waihona protein maʻamau ʻole.

ʻO nā lāʻau lapaʻau nui no ka maʻi o Alzheimer

Hiki ke hoʻokaʻawale ʻia nā lāʻau lapaʻau no ka maʻi Alzheimer i ʻelua mau ʻāpana nui. ʻO kekahi ka lāʻau lapaʻau e kāohi ana i nā hōʻailona. ʻO kekahi ka lāʻau lapaʻau hou e hoʻāʻo nei e kāohi i ka holomua o ka maʻi, ʻo ia hoʻi, ka ʻino ʻana o ka maʻi.

1. Nā mea pale i ka Cholinesterase

ʻO kēia nā lāʻau lapaʻau i kuhikuhi pinepine ʻia no nā poʻe maʻi i nā pae mua a me waena o ka maʻi Alzheimer.

Pehea lākou e hana ai?

I ka ʻōlelo maʻalahi, loaʻa i ko kākou lolo kahi ʻelele kemika i kapa ʻia ʻo acetylcholine , he mea nui ia no nā mea e like me ka hoʻomanaʻo a me ke aʻo ʻana. I ka maʻi Alzheimer, emi nā pae o kēia acetylcholine. ʻO ka hana a kēia mau lāʻau lapaʻau, ʻo ia ke kāohi i ka haki ʻana o ka acetylcholine i loko o ka lolo. ʻAe kēia i ka hoʻouna ʻana o nā leka ma waena o nā hunaola nerve i kahi ʻoi aku ka maikaʻi.

He aha nā hopena ʻaoʻao o kēia mau mea?

ʻAʻole loaʻa i nā kānaka a pau nā hopena ʻaoʻao, akā hiki i kekahi poʻe ke loaʻa i ka nausea, ka luaʻi ʻana, ka ʻeha o ka ʻōpū, ka pehu ʻana, a me ka luhi.

2. Memantine

ʻO ka maʻamau, hāʻawi ʻia kēia lāʻau lapaʻau i nā poʻe ma nā pae waena a koʻikoʻi o ka maʻi. I kekahi manawa, hāʻawi paha ke kauka iā ia me ka Donepezil i ʻōlelo ʻia ma luna.

Pehea lā e hana ai?

ʻO kekahi ʻelele kemika ʻē aʻe i loko o ka lolo i kapa ʻia ʻo glutamate e lilo i kiʻekiʻe loa i ka maʻi Alzheimer. Hiki i kēia ke hōʻino i nā hunaola nerve. Hana ʻo Memantine ma ke kāohi ʻana i kēia mau pae glutamate. Hiki i kēia ke kōkua i ka hoʻomaikaʻi ʻana i ka nānā ʻana o ka mea maʻi, ka noʻonoʻo ʻana, a me ka ʻōlelo. Hiki iā ia ke kōkua i ka kāohi ʻana i nā hōʻailona e like me ka hoʻomaha ʻole, ka huhū, a me ka ʻike/lohe ʻana i nā mea ʻaʻole ma laila .

Nā hopena ʻaoʻao: Hiki ke loaʻa ka paʻa ʻana o ka ʻōpū, ka poniuniu, ka ʻeha poʻo, a me ka hiamoe.

3. Nā lāʻau lapaʻau hou e kuhikuhi ana i nā waihona amyloid i loko o ka lolo

ʻO kēia nā holomua hou loa i ka mālama ʻana iā Alzheimer. He mau lāʻau lapaʻau kūikawā kēia i kapa ʻia ʻo "monoclonal antibodies." Kuhi pololei kēia i nā waihona protein ʻino i kapa ʻia ʻo nā plaques amyloid e hōʻiliʻili ana i loko o ka lolo. Hāʻawi ʻia lākou ma o kahi vein (IV). I kēia manawa ua ʻae ʻia lākou no nā poʻe maʻi i nā wā mua loa o ka maʻi.

• ʻO Lecanemab (Leqembi)
• ʻO Donanemab (Kisunla)

Ua hōʻike ʻia kēia mau lāʻau lapaʻau ma nā hoʻokolohua e hoʻolohi nui i ka holomua o ka maʻi. Eia nō naʻe, hiki iā lākou ke hana i nā hopena ʻino e like me ka pehu ʻana o ka lolo no ka manawa pōkole a i ʻole ke kahe koko liʻiliʻi, no laila hāʻawi ʻia me ke akahele loa a ma lalo wale nō o ka nānā pono ʻana a ke kauka.

Nā mea āu e pono ai e makaʻala i ka wā e hāʻawi ai i ka lāʻau lapaʻau i ka mea maʻi

Ma ke ʻano he mea mālama no kekahi me Alzheimer's, he kuleana nui kou, ʻoiai ka hāʻawi ʻana iā lākou i kā lākou lāʻau i ka manawa kūpono. Aia kekahi mau mea e pono ai ʻoe e makaʻala.

I nā pae mua o ka maʻi:

ʻOiai hiki i ka mea maʻi ke lawe i ka lāʻau lapaʻau iā lākou iho i ka hoʻomaka ʻana, hiki iā lākou ke poina mālie iā ia. E hana i kēia mau mea e kōkua iā lākou.

• E hoʻohana i kahi mea hoʻonohonoho pila: E hoʻonohonoho pono i kāu mau lāʻau lapaʻau no ka pule. ʻOi aku ka maikaʻi o ka loaʻa ʻana o hoʻokahi me nā ʻāpana no ke kakahiaka, ke awakea, a me ke ahiahi.
• E hoʻomanaʻo iā ʻoe iho i ka manawa kūpono: E hoʻonohonoho i kahi alarm ma kāu kelepona. A i ʻole, inā hiki iā ʻoe, e kelepona a hoʻomanaʻo iā ʻoe iho i kēlā manawa.
• E kamaʻilio me lākou: E nīnau iā lākou me ke aloha, "Hiki iaʻu ke kōkua iā ʻoe e kiʻi i kāu lāʻau lapaʻau?" E kōkua iā lākou me ka mahalo i ko lākou kūʻokoʻa.

Ke koʻikoʻi ka maʻi:

I ka hala ʻana o ka manawa, pono ʻoe e lawe i ke kuleana piha no ka lawelawe ʻana i ka lāʻau lapaʻau.

• Inā pilikia ʻoe i ka ale ʻana i nā pila: Hiki paha no ka maloʻo o kou waha. E hāʻawi i kāu keiki i ka wai e inu ma mua o ka hāʻawi ʻana iā lākou i ka lāʻau. Akā inā ʻaʻole holo pono kēlā, e nīnau i kāu kauka inā hiki ke kuʻi ʻia ka lāʻau a kāwili ʻia me ka meaʻai, a i ʻole inā loaʻa ia ma ke ʻano wai. ʻAʻole maikaʻi nā lāʻau āpau e kuʻi ʻia , no laila e nīnau pono i kāu kauka.
• Inā ʻōlelo lākou ʻaʻole hiki iā lākou ke lawe i ka lāʻau lapaʻau: Mai hakakā me lākou. ʻO ia wale nō ka mea e hoʻonāukiuki hou aku ai iā lākou. I kēlā manawa, e hoʻōki i ka lawe ʻana, e kali iki, a hoʻāʻo hou. Malia paha e lawe lākou inā e hoʻomanaʻo mālie ʻoe iā lākou, "ʻO kēia ka lāʻau lapaʻau no kou pilikia." Inā hoʻomau lākou i ka hōʻole, e haʻi i kāu kauka.
• E mālama i kahi papa inoa lāʻau: E kākau i lalo i kēlā me kēia lāʻau lapaʻau, ka wikamina, a me ka nui o ka lāʻau a lākou e lawe ai, a me ka manawa a lākou e lawe ai. E lawe pū me ʻoe i kēia papa inoa ke hele ʻoe e ʻike i ke kauka.
• E mālama pono i kāu mau lāʻau lapaʻau: E mālama i nā lāʻau lapaʻau a pau i loko o kahi keʻena paʻa, kahi i hiki ʻole ai i nā keiki a me ka mea maʻi ke kiʻi aku.