Ua kuhikuhi anei kekahi kauka iā ʻoe i kahi ʻano lāʻau i kapa ʻia ʻo SNRI no kou kaumaha a i ʻole ka hopohopo mau? Malia paha kekahi o kou mau hoaaloha e hoʻohana nei i kēia lāʻau. Ua hopohopo iki paha ʻoe i kou lohe ʻana i kēia inoa. He nui paha kāu mau nīnau i loko o kou manaʻo e like me, "He aha kēia lāʻau? He maikaʻi anei kēia no ke kino?" No laila, i kēia lā, e kamaʻilio kākou e pili ana i kēia ʻano lāʻau i kapa ʻia ʻo SNRI me ka maʻalahi loa, me he mea lā e kamaʻilio ana ʻoe me kahi hoaaloha.
I ka ʻōlelo maʻalahi, he aha kēia mau SNRI?
ʻO ke ʻano piha o SNRI ʻo Serotonin a me Norepinephrine Reuptake Inhibitors . ʻAe, kani paʻakikī iki ka inoa, ʻeā? E wehewehe kākou a e hoʻomaopopo maʻalahi.
I loko o ko kākou lolo, aia nā ʻelele kemika kūikawā e kaohi ana i nā mea he nui, me ko kākou mau manaʻo, nā manaʻo, ka hiamoe, a me ka makemake. Kāhea mākou i kēia mau "Neurotransmitters." E like me ka mea lawe leka, lawe kēia mau ʻelele i nā leka mai kekahi ʻāpana o ka lolo a i kekahi ʻāpana.
ʻO ʻelua o kēia mau ʻelele he serotonin a me norepinephrine .
- He mea nui loa ka Serotonin no nā mea e like me ko kākou ʻano, ka hiamoe, a me ka ʻai ʻana. Ke kiʻekiʻe nā pae serotonin, hauʻoli a hoʻomaha mākou.
- Kōkua ʻo Norepinephrine iā mākou e noho paʻa, ikaika, a hana.
ʻO ka mea maʻamau e hana ʻia ana, ma hope o ka hāʻawi ʻana o kēia mau ʻelele i kā lākou leka, hoʻihoʻi nā hunaola o ka lolo iā lākou. Ua kapa ʻia kēia ʻo "Reuptake." E like me ka hoʻi ʻana o ka mea lawe leka i ke keʻena leka ma hope o ka hāʻawi ʻana i kahi leka.
Eia nō naʻe, i nā poʻe me nā kūlana e like me ke kaumaha a me ka hopohopo paha, hiki ke hoʻemi iki ʻia ka hana o kēia mau ʻelele serotonin a me norepinephrine i loko o ka lolo.
ʻO kēia kahi e komo mai ai nā lāʻau SNRI. ʻO ka hana a kēia mau lāʻau lapaʻau, ʻo ia ke ālai i ka lawe hou ʻana o kēlā mau ʻelele no kekahi manawa. Ua like ia me ka haʻi ʻana i ka mea lawe leka e "kali iki a hāʻawi i kekahi mau leka hou aku." A laila noho kēia mau ʻelele maikaʻi (serotonin a me norepinephrine) i loko o ka lolo no ka manawa lōʻihi a hana i kā lākou hana maikaʻi. Hoʻomaka kēia e hoʻomaikaʻi i ko mākou ʻano, hoʻēmi i ka hopohopo, a hoʻonui i ko mākou ikehu.
I ka ʻōlelo maʻalahi, ʻo SNRI kahi ʻano lāʻau lapaʻau e kōkua iā mākou e ʻoluʻolu ma ke kaulike ʻana i nā pae o nā kemika kūlohelohe i loko o ko mākou lolo e kaohi ana i ka "hauʻoli a me ka ikaika."
He aha nā kūlana e hoʻohana ʻia ai nā lāʻau lapaʻau SNRI?
ʻOiai ua kuhikuhi nui ʻia kēia mau lāʻau lapaʻau no nā pilikia olakino noʻonoʻo, kuhikuhi pū nā kauka iā lākou no kekahi mau maʻi kino ʻē aʻe. E nānā kākou i ke ʻano o lākou.
| Maʻi | He wehewehe maʻalahi |
|---|---|
| Nā manawa i ʻōlelo nui ʻia | |
| Ka maʻi kaumaha nui | E hōʻoluʻolu i nā hōʻailona e like me ke kaumaha lōʻihi, ka nalowale o ka hoihoi i kekahi mea, a me ka luhi me ke ola. |
| Ka maʻi hopohopo laulā | E kāohi i ka makaʻu, ka hopohopo, a me ka hoʻomaha ʻole e hiki mau mai ana i ka noʻonoʻo me ke kumu ʻole. |
| Ka maʻi hopohopo pili kanaka | E hoʻēmi i ka makaʻu nui a me ka hilahila i ka ʻōlelo ʻana a me ka hana ʻana i mua o kekahi poʻe. |
| Ka maʻi hopohopo | I mea e pale aku ai i nā hoʻouka kaua koke a hiki ʻole ke kaohi ʻia. |
| ʻEha mau loa | No ka hōʻoluʻolu ʻana i ka ʻeha mau loa i hoʻokumu ʻia e nā kūlana e like me ka neuropathy pili i ka maʻi diabetes a me ka fibromyalgia. |
| Nā hihia ʻē aʻe (Hoʻohana ma waho o ka lepili) | |
| Ka maʻi hoʻopilikia-koʻikoʻi (OCD) | E kāohi i ka hanana pinepine ʻana o nā manaʻo i makemake ʻole ʻia a me ka hana hou ʻana o kekahi mau mea i ka pane ʻana iā lākou. |
| Nā hōʻailona o ka menopause | No ka kaohi ʻana i nā hōʻailona e like me nā ʻā wela e kū mai ana me ka menopause. |
| Nā migraines | Ma ke ʻano he lāʻau lapaʻau e pale aku ai i ka migraines. |
Ke noʻonoʻo nei paha ʻoe i ke ʻano o ka "hoʻohana ma waho o ka lepili". ʻO ia hoʻi, ke kuhikuhi nei ke kauka, ma muli o kona ʻike lapaʻau a me kona ʻike, i kahi lāʻau no kekahi maʻi ʻē aʻe, ma waho aʻe o ke ʻano nui i ʻae ʻia ai. He mea kēia i hana pinepine ʻia.
He aha nā ʻano SNRI maʻamau ma Sri Lanka?
Aia kekahi mau ʻano lāʻau lapaʻau SNRI. E koho kāu kauka i ka lāʻau lapaʻau kūpono loa nāu ma muli o kou kūlana, makahiki, a me nā kūlana olakino ʻē aʻe.
- ʻO Venlafaxine (e like me ka inoa inoa ʻo Effexor®)
- ʻO Duloxetine (e like me ka inoa inoa ʻo Cymbalta®)
- ʻO Desvenlafaxine (inoa inoa ʻo Pristiq®)
- Milnacipran (inoa inoa Savella®)
- ʻO Levomilnacipran (e like me ka inoa inoa ʻo Fetzima®)
Aia paha kekahi o nā mea i luna i loko o ka lāʻau lapaʻau i loaʻa iā ʻoe.
He aha nā hopena ʻaoʻao e hiki ke loaʻa mai ka hoʻohana ʻana i kēia lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, hiki i kēia ke loaʻa nā hopena ʻaoʻao liʻiliʻi. Akā no ka hapa nui o ka poʻe, ʻaʻole koʻikoʻi kēia. ʻIke pinepine ʻia lākou i nā pule mua o ka lawe ʻana i ka lāʻau lapaʻau a laila nalo aku i ka wā e hoʻomaʻamaʻa ai kou kino i ka lāʻau lapaʻau.
| Ka hopena ʻaoʻao | Wehewehena |
|---|---|
| Nā pilikia o ka ʻōnaehana hoʻoheheʻe | Ka luaʻi, ka ʻōpū ʻeha, ka paʻa ʻana o ka ʻōpū, a i ʻole ka maʻi pākī. |
| ʻO ka poniuniu (vertigo) | ʻO ka poniuniu, ʻoiai ke kū a hoʻololi paha i nā kūlana. |
| Waha maloʻo | He manaʻo o ka hōʻiliʻili ʻana o ka lawai i loko o ka waha. Hiki ke kāohi ʻia kēia ma ka inu ʻana i kahi wai hou aʻe. |
| Ka hou nui ʻana | Hiki ke hoʻonui ʻia ka hou ʻana, ʻoi aku hoʻi i ka pō. |
| Nā pilikia hiamoe | Hiki i kekahi poʻe ke loaʻa i ka hiamoe ʻole. Hiki i kekahi ke manaʻo i ka hiamoe nui loa. |
| Nā pilikia moekolohe | Hiki ke loaʻa nā mea e like me ka emi ʻana o ka makemake moekolohe a me ka paʻakikī i ka ejaculation. Mai hilahila e kamaʻilio me kāu kauka e pili ana i kēia. |
ʻO ka mea nui loa, inā loaʻa iā ʻoe kahi hopena ʻaoʻao e like me kēia, a he nui loa ia e hiki ke hoʻomanawanui, mai hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau iā ʻoe iho. E hōʻoia e kamaʻilio me kāu kauka no ka ʻōlelo aʻo.
Nā kūlana pilikia kūikawā e makaʻala ai
ʻOiai he lāʻau lapaʻau palekana nā SNRI, he mea maikaʻi ke ʻike i kekahi mau pilikia koʻikoʻi, ʻoiai hiki ke loaʻa pinepine ʻole.
1. Ka maʻi Serotonin
ʻO kēia ka mea nui e makaʻala ai. Ke lawe pū ʻia nā SNRI a me nā lāʻau lapaʻau ʻē aʻe e hoʻopilikia ana i nā pae serotonin, hiki i nā pae serotonin i loko o ka lolo ke lilo i kiʻekiʻe pono ʻole. He pilikia olakino koʻikoʻi kēia.
- Nā Hōʻailona: Huikau i wehewehe ʻole ʻia, ka puʻuwai wikiwiki, ke kuni nui, nā ʻiʻo ʻoʻoleʻa a ʻūlū paha, a me ka hou nui.
- He aha e hana ai: Inā loaʻa koke iā ʻoe a i ʻole kekahi āu i ʻike ai kēia mau hōʻailona, e ʻike koke i ke kauka a i ʻole e hele i ka Emergency Department (ETU) o ka haukapila kokoke loa.
2. Nā hōʻailona e kū mai ana i ka wā e hoʻōki ai i ka lāʻau lapaʻau (Antidepressant Discontinuation Syndrome)
Inā ʻoe e lawe i kēia lāʻau lapaʻau no ka manawa lōʻihi a hoʻōki koke, hiki i kou kino ke ʻike i ka ʻeha ma ke ʻano he hopena iā ia.
- Nā ʻano:Pōniuniu, ʻeha poʻo, luaʻi, ʻeha kino (e like me ke kuni), a me ka hopohopo nui.
- Kāohi: Mai hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau me ka ʻole o ke kūkākūkā ʻana me kāu kauka. Inā pono ʻoe e hoʻōki, e hoʻēmi mālie kāu kauka i ka nui o ka lāʻau ma luna o hoʻokahi a ʻelua paha mahina, e hoʻololi i kou kino, a laila e hōʻike iā ʻoe pehea e hoʻōki ai me ka palekana.
3. Nā manaʻo pepehi kanaka
He kumuhana koʻikoʻi loa kēia, akā he mea ia e pono e kamaʻilio ʻia. Ua ʻike ʻia nā noiʻi he liʻiliʻi loa ka pilikia o ka hoʻonui ʻia ʻana o nā manaʻo pepehi kanaka, ʻoiai hoʻi i nā poʻe ʻōpio ma lalo o 25 mau makahiki , i nā pule mua o ka hoʻohana ʻana i kēia lāʻau lapaʻau.
- He mea nui: Inā loaʻa iā ʻoe kēia mau manaʻo, e ʻoluʻolu, mai ʻeha hoʻokahi. ʻAʻole kēia kou hewa, he hopena ʻaoʻao paha ia o ka lāʻau lapaʻau. E haʻi koke aku i kāu kauka. E haʻi aku i kahi lālā o ka ʻohana a i ʻole hoaaloha āu e hilinaʻi nei. He mea hoʻoikaika ka noi ʻana i ke kōkua.
Nā mea ʻē aʻe e noʻonoʻo ai i ka wā e lawe ai i nā SNRI
Ka inu ʻana i ka waiʻona
ʻOi aku ka maikaʻi o ka pale ʻana i ka inu ʻana i ka waiʻona i ka wā e lawe ana i nā lāʻau antidepressants e like me SNRIs. He mea hoʻohaʻahaʻa pū kekahi ka waiʻona i ka ʻōnaehana nerve waena. No laila, hiki iā ia ke hoʻopilikia i ka pono o ka lāʻau lapaʻau. I kekahi manawa hiki i ka waiʻona ke hoʻonui i nā hōʻailona o ke kaumaha.
Nā lāʻau lapaʻau ʻē aʻe
Inā ʻoe e lawe ana i kahi SNRI, e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei (nā lāʻau hoʻopau ʻeha, nā lāʻau kuni, nā huaora, a me nā lāʻau lapaʻau lāʻau). Hiki i kekahi mau lāʻau lapaʻau ke launa pū me nā SNRI.
- Nā lāʻau hoʻopau ʻeha e like me NSAID (e.g. Ibuprofen, Diclofenac)
- Nā lāʻau lapaʻau e pale ai i ke kāpili ʻana o ke koko (e like me Aspirin, Clopidogrel)
- He lāʻau lapaʻau migraine nā Triptans .
- Nā huahana lāʻau lapaʻau e like me ka St. John's Wort
Ka hāpai ʻana a me ka hānai ʻana i ka waiū
Inā ʻoe e hoʻolālā ana e hāpai, ua hāpai mua, a i ʻole e hānai waiū ana, pono ʻoe e kamaʻilio me kāu kauka e pili ana i ka hoʻohana ʻana i kēia lāʻau lapaʻau. Hiki i kekahi mau SNRI ke hoʻopilikia i ka pēpē i loko o ka ʻōpū. Eia kekahi, ʻo ka hoʻōki koke ʻana i ka lāʻau lapaʻau hiki ke hōʻino i ka makuahine. Hiki i kāu kauka ke kōkua iā ʻoe e hoʻoholo i ke koho palekana loa no ʻoe a me kāu pēpē.
ʻEhia ka lōʻihi o ka hana ʻana o ka lāʻau lapaʻau?
He nīnau kēia a ka poʻe he nui e nīnau ai. ʻAʻole nā SNRI he lāʻau lapaʻau e hana koke e like me Panadol. He manawa iki ka lōʻihi no ke kaulike ʻana o nā kaʻina hana kemika o ka lolo.
- E ʻike ka hapa nui o ka poʻe i kekahi hoʻomaikaʻi (holomua) i nā hōʻailona i loko o 4 a 6 mau pule .
- Hiki ke hala ma waena o 9 a me 12 mau pule (2-3 mau mahina) no kekahi poʻe e loaʻa ai ka pono piha o ka lāʻau lapaʻau.
No laila, mai ho'ōki i ka lawe ʻana i ka lāʻau lapaʻau no ka mea ʻaʻole ʻoe e ʻike i ka ʻokoʻa nui i nā pule mua.E hoʻomanawanui. Inā ʻaʻole ʻoe e ʻike i kekahi ʻokoʻa ma hope o kēlā manawa, e kamaʻilio hou me kāu kauka. Hiki paha iā ia ke hoʻololi i ka nui o ka lāʻau a hoʻololi paha iā ʻoe i kahi lāʻau lapaʻau ʻē aʻe.
Leka Lawe-Home
- He mau lāʻau lapaʻau maikaʻi nā SNRI e kōkua ai i ka kaohi ʻana i ke kaumaha, ka hopohopo, a me kekahi mau ʻeha ma ke kaulike ʻana i ka hana o nā ʻelele kemika kūlohelohe i kou lolo.
- ʻAʻole hana koke kēia lāʻau lapaʻau. Pono ʻoe e hoʻomanawanui a kali i kekahi mau pule e ʻike i nā hopena.
- E like me nā lāʻau lapaʻau āpau, aia paha nā hopena ʻaoʻao liʻiliʻi. Hoʻomaha pinepine lākou i ka hala ʻana o ka manawa. Inā loaʻa iā ʻoe kekahi ʻeha hiki ʻole ke hoʻomanawanui, e haʻi i kāu kauka.
- Mai ho'ōki koke i ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻole o ke kūkākūkā ʻana me kāu kauka, no kekahi kumu. ʻO ka hana ʻana pēlā e hōʻike ai i nā hōʻailona maikaʻi ʻole.
- He mea nui e hoʻomaopopo i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, inā ʻoe e inu waiʻona, a inā ʻoe e hāpai.
- Inā he mau nīnau kāu, hopohopo, a kānalua paha e pili ana i kāu lāʻau lapaʻau, e kūkākūkā ākea me kāu kauka. ʻO ia kāu kākāʻōlelo maikaʻi loa a hilinaʻi nui ʻia.
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