Koj puas xav tias koj nkees thiab qaug zog zuj zus txhua hnub? Nrog rau mob plab thiab xeev siab, koj puas muaj tej lub sij hawm koj xav noj cov khoom qab ntsev txawv txawv? Txawm hais tias tej no zoo li yog tej yam ib txwm muaj, tej zaum tom qab qhov no yog ib yam mob uas peb tsis tau hnov dua txog, tab sis yuav tsum tau tswj kom zoo. Hnub no peb tab tom tham txog ib yam mob zoo li no, kab mob Addison.
Kab mob Addison yog dab tsi tiag?
Hais yooj yim xwb, tus kab mob Addison yog ib qho mob ntev uas tshwm sim thaum cov qog adrenal hauv peb lub cev tsis tsim txaus ob lub tshuaj hormones tseem ceeb, cortisol thiab aldosterone .
Tam sim no tej zaum koj yuav xav paub tias cov qog adrenal yog dab tsi. Cov no yog ob lub qog me me, peb ceg uas zaum zoo li lub hau saum peb lub raum. Lawv yog ib feem tseem ceeb ntawm peb lub cev endocrine system.
- Cortisol: Cov tshuaj hormones no tseem ceeb rau peb lub neej. Xav txog thaum koj mob, muaj xwm txheej, lossis phais, koj lub cev xav tias muaj kev ntxhov siab ntau. Thaum lub sijhawm zoo li no, cov tshuaj cortisol pab lub cev daws qhov kev ntxhov siab ntawd. Tsis yog li ntawd xwb, tab sis nws kuj pab tswj cov ntshav siab, lub plawv ua haujlwm, lub cev tiv thaiv kab mob, thiab cov ntshav qab zib.
- Aldosterone: Cov tshuaj hormones no tswj qhov sib npaug ntawm sodium (ntsev) thiab potassium hauv peb cov ntshav. Nws kuj tswj cov kua dej ntau npaum li cas uas peb lub raum tso tawm ua zis. Qhov no cuam tshuam ncaj qha rau peb cov ntshav ntim thiab ntshav siab.
Kab mob Addison kuj hu ua primary adrenal insufficiency . Muaj lwm yam mob zoo li no hu ua secondary adrenal insufficiency . Hauv qhov mob no, lub qog pituitary hauv lub hlwb tsis tsim cov tshuaj hormones hu ua ACTH txaus. Cov tshuaj hormones no, ACTH, ua rau cov qog adrenal tsim cov cortisol.
Qhov txawv ntawm tus kab mob Addison thiab Cushing's syndrome yog dab tsi?
Tsis txhob xav ob yam no ua ke. Nws yooj yim heev.
- Kab mob Addison: Tsis muaj cortisol (thiab aldosterone) txaus hauv lub cev.
- Cushing's Syndrome: Muaj cortisol ntau ntxiv hauv lub cev.
Leej twg yuav muaj tus mob no tshaj?
Txawm hais tias tus kab mob Addison tuaj yeem tshwm sim thaum twg los tau, nws feem ntau tshwm sim ntawm hnub nyoog 30 thiab 50 xyoo.Ntawm cov neeg. Qhov no yog ib qho mob tsis tshua muaj.
Tsis tas li ntawd xwb, cov neeg uas muaj qee yam kab mob autoimmune muaj feem yuav mob nws ntau dua. Kab mob autoimmune yog thaum peb lub cev tiv thaiv kab mob tsis raug rau peb cov hlwb noj qab haus huv. Cov neeg uas muaj cov kab mob hauv qab no muaj feem yuav mob Addison's ntau dua:
- Kab mob ntshav qab zib hom I
- Kev mob ntshav tsis txaus
- Kab mob Graves
- Mob thyroiditis ntev
- Dermatitis herpetiformis
- Vitiligo
- Myasthenia gravis
Cov tsos mob ntawm tus kab mob Addison yog dab tsi?
Hauv tus kab mob no, kev puas tsuaj rau cov qog adrenal feem ntau tshwm sim qeeb qeeb, dhau sijhawm. Yog li ntawd, cov tsos mob tshwm sim maj mam. Cov tsos mob no tuaj yeem sib txawv ntawm ib tus neeg mus rau ib tus neeg.
| Cov tsos mob | Kev piav qhia |
|---|---|
| Kev xav tias qaug zog heev tas li | Qhov no yog ib qho tsos mob uas tshwm sim ntau zaus thiab maj mam zuj zus tuaj. |
| Cov pob tsaus ntawm daim tawv nqaij (Hyperpigmentation) | Daim tawv nqaij tsaus zuj zus, tshwj xeeb tshaj yog cov qhov txhab, cov qhov txhab caws pliav, cov tawv nqaij zawm (lub luj tshib, lub hauv caug), thiab cov pos hniav. |
| Mob plab, xeev siab, thiab ntuav | Teeb meem ntawm lub cev zom zaub mov. |
| Mob plab (raws plab) | Mob plab ntau zaus nrog rau raws plab. |
| Tsis qab los noj mov thiab poob phaus | Poob phaus thiab tsis xav noj mov yam tsis muaj laj thawj pom tseeb. |
| Mob nqaij thiab mob pob qij txha | Cov mob xws li mob lub cev thiab cov leeg nqaij ntswj. |
| Ntshav Siab Qis | Hnov kiv taub hau thiab tsaus muag thaum sawv ntsug. |
| Kev ntshaw ntsev ntau dhau | Ib qho tsos mob uas tshwm sim los ntawm kev txo qis ntawm cov ntsev hauv lub cev. |
| Ntshav Qab Zib Qis (Hypoglycemia) | Tej zaum yuav muaj cov tsos mob xws li mob lub cev thiab tawm hws. |
| Kev hloov pauv ntawm lub hlwb | Kev npau taws, kev nyuaj siab, thiab kev nyuaj siab tsom ntsoov tsis tau vim yog. |
Yog tias cov poj niam muaj tus kab mob no, lawv kuj tseem yuav muaj cov tsos mob xws li kev coj khaub ncaws tsis tu ncua, cov plaub hau poob ntawm lub cev, thiab kev xav sib deev tsawg dua.
Xwm Ceev: Addisonian Crisis yog dab tsi?
Qee zaum, tshwj xeeb tshaj yog thaum lub sijhawm muaj kev ntxhov siab ntau rau lub cev (piv txwv li, muaj mob hnyav, muaj xwm txheej), cov tsos mob tuaj yeem hnyav zuj zus thiab ua rau tuag taus. Qhov no hu ua Addisonian crisis , lossis mob adrenal tsis ua haujlwm sai .
Qhov no yog xwm txheej ceev hauv kev kho mob. Yog tias tsis kho kom zoo, yuav ua rau poob siab thiab tuag taus.
Yog tias koj lossis ib tus neeg koj paub muaj cov tsos mob hauv qab no, coj lawv mus rau Chav Kho Mob Ceev (ETU) ze tshaj plaws tam sim ntawd.
| Cov cim qhia txog Addisonian Crisis | |
|---|---|
| 1. | Muaj kev qaug zog thiab tsis muaj zog sai sai. |
| 2. | Mob tam sim ntawd, mob hnyav rau hauv plab qis, nraub qaum, lossis ob txhais ceg. |
| 3. | ntuav thiab raws plab hnyav heev, ua rau lub cev qhuav dej. |
| 4. | Ntshav siab poob qis dhau. |
| 5. | Kev xav tsis meej pem, tsis nyob twj ywm, lossis ntshai. |
| 6. | Poob siab. |
Dab tsi ua rau muaj tus kab mob Addison?
Qhov ua rau muaj kab mob Addison yog vim muaj kab mob autoimmune . Yog hais yooj yim xwb, peb lub cev tiv thaiv kab mob (lub cev tiv thaiv kab mob) ua yuam kev tawm tsam peb cov nqaij mos noj qab haus huv. Hauv tus kab mob no, lub cev tiv thaiv kab mob tawm tsam sab nraud ntawm cov qog adrenal (lub adrenal cortex). Qhov no yog qhov uas cortisol thiab aldosterone tsim tawm. Cov tsos mob feem ntau tsis tshwm sim kom txog thaum txog li 90% ntawm qhov kev puas tsuaj no tau tshwm sim. Qhov no tuaj yeem siv sijhawm ntau lub hlis, lossis txawm tias ntau xyoo. Qhov no yog qhov ua rau 75% ntawm cov neeg mob Addison.
Yav dhau los, tus kab mob ntsws yog ib qho ua rau muaj qhov no, thiab nws tseem yog ib qho ua rau muaj teeb meem loj hauv cov teb chaws uas tseem tab tom txhim kho.
Muaj lwm yam laj thawj tsis tshua muaj:
- Cov kab mob xws li HIV/AIDS thiab cov kab mob fungal.
- Kev kis ntawm cov qog nqaij hlav los ntawm lwm qhov mus rau cov qog adrenal.
- Kev los ntshav rau hauv cov qog adrenal (hemorrhaging).
- Kev phais tshem tawm cov qog adrenal.
- Cov kab mob xws li amyloidosis.
Tus kws kho mob kuaj mob li cas?
Vim tias cov tsos mob maj mam tshwm sim thiab yog ib qho uas tshwm sim rau ntau lwm yam kab mob, nws yuav nyuaj rau kev kuaj mob no kom raug.
Feem ntau, tus kws kho mob yuav ua rau muaj kev tsis ntseeg thaum kev kuaj ntshav qhia tias muaj cov ntsev tsawg lossis cov potassium ntau hauv cov ntshav. Cov pob tsaus ntawm daim tawv nqaij yog lwm yam tsos mob tseem ceeb uas ua rau ib tus neeg xav tias qhov no.
Yog koj tus kws kho mob xav tias muaj kab mob Addison raws li koj cov tsos mob, lawv yuav xaj ntau qhov kev kuaj ntxiv kom paub tseeb tias koj tau kuaj mob.
- Kev kuaj ntshav: Cov no ntsuas cov sodium, potassium, cortisol, thiab ACTH cov tshuaj hormones hauv koj cov ntshav.
- Kev kuaj ACTH: Qhov no suav nrog kev txhaj tshuaj hormone ACTH thiab saib seb koj cov qog adrenal puas tsim cortisol los teb. Cov cortisol qis yuav qhia tau tias cov qog tsis ua haujlwm zoo.
- Kev kuaj ntshav qab zib qis vim yog insulin: Qhov no kuaj seb koj qhov teeb meem puas cuam tshuam nrog lub qog pituitary.
- CT scan: Qhov no tuaj yeem kuaj xyuas seb puas muaj kev puas tsuaj rau cov qog adrenal lossis kev kis kab mob.
Cov kev kho mob rau qhov no yog dab tsi?
Kab mob Addison kho tau los ntawm kev hloov cov tshuaj hormones uas ploj lawm hauv lub cev nrog cov tshuaj tsim tawm.
- Muab tshuaj hu ua hydrocortisone hloov cortisol.
- Aldosterone raug hloov nrog cov tshuaj hu ua fludrocortisone .
Kab mob Addison yog ib yam mob uas mob ntev mus tas li, yog li koj yuav tsum noj cov tshuaj no mus tas koj lub neej .
Qhov ntau npaum li cas ntawm cov tshuaj no txawv ntawm ib tus neeg mus rau ib tus neeg. Tsis tas li ntawd, koj tus kws kho mob yuav nce qhov ntau npaum li cas ntawm cov tshuaj kom tiv thaiv tau qhov teeb meem Addisonian yog tias koj muaj kev ntxhov siab, xws li kev kis kab mob, kev sib tsoo, lossis kev phais.
Yog koj muaj tus kab mob Addison, koj yuav saib xyuas koj tus kheej li cas?
Yog koj muaj tus kab mob no, nws yog ib qho tseem ceeb heev uas koj yuav tsum saib xyuas koj tus kheej.
- Ib txwm hnav daim npav ID lossis lub kauj tes ceeb toom kev kho mob kom cov kws kho mob paub txog koj tus mob yog tias muaj xwm txheej ceev.
- Tham nrog koj tus kws kho mob txog yam koj yuav tsum ua thaum koj mob lossis muaj kev ntxhov siab ntau, vim tias koj cov tshuaj noj yuav tsum tau hloov kho thaum lub sijhawm zoo li no.
- Rau qhov xwm txheej ceevNug koj tus kws kho mob txog kev khaws cov tshuaj cortisol txhaj rau tes thiab qhia ib tug neeg hauv tsev neeg yuav ua li cas muab rau koj.
Thaum twg koj yuav tsum mus ntsib koj tus kws kho mob?
Yog tias koj muaj tus kab mob Addison, koj yuav tsum mus ntsib koj tus kws kho mob (feem ntau yog tus kws kho mob endocrinologist) tsis tu ncua kom paub tseeb tias koj cov tshuaj noj yog rau koj.
Yog tias koj muaj kev ntxhov siab loj heev, xws li muaj xwm txheej, muaj mob, lossis muaj ib tus neeg koj hlub tuag, hu rau koj tus kws kho mob vim tias tej zaum koj yuav tsum hloov qhov ntau npaum li cas ntawm koj cov tshuaj.
Yog tias muaj cov tsos mob ntawm Addisonian crisis (xws li qaug zog sai sai, mob hnyav) tshwm sim, mus rau chav kho mob ceev (ETU) ntawm tsev kho mob tam sim ntawd kom tau kev kho mob.
Paub tias koj muaj mob ntev ntev tuaj yeem ua rau koj lub siab ntxhov siab. Tab sis qhov xov xwm zoo yog tias tus kab mob Addison tuaj yeem tswj tau zoo nrog tshuaj. Los ntawm kev mus ntsib koj tus kws kho mob tsis tu ncua, noj tshuaj kom raug, thiab saib xyuas koj tus kheej, koj tuaj yeem ua neej noj qab nyob zoo thiab zoo li qub.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Kab mob Addison yog ib qho mob tsis tshua muaj, mob ntev uas cov qog adrenal tsis tsim cov tshuaj hormones cortisol thiab aldosterone txaus.
- Cov tsos mob tseem ceeb suav nrog qaug zog ntxiv, cov tawv nqaij dub (tshwj xeeb tshaj yog qhov twg daim tawv nqaij quav), thiab ntshaw zaub mov ntsev ntau dhau.
- Kab mob Addisonian yog ib qho xwm txheej ceev uas yuav ua rau tuag taus, thiab yog tias muaj cov tsos mob tshwm sim, koj yuav tsum mus rau chav kho mob ceev (ETU) ntawm tsev kho mob tam sim ntawd.
- Kev kho mob yuav tsum tau siv tshuaj hormone hloov kho mus tas li.
- Los ntawm kev ua raws li cov lus qhia kho mob kom raug thiab noj koj cov tshuaj raws nraim li qhia, koj tuaj yeem ua neej noj qab nyob zoo thiab ib txwm muaj.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus