Thaum koj tus kws kho mob qhia koj tias koj muaj mob qog noj ntshav, koj muaj ntau lo lus nug hauv koj lub siab, puas yog? Peb tau hnov txog 'chemo' thiab 'radiation', tab sis koj tus kws kho mob tej zaum yuav tham txog ib pawg tshuaj tshiab hu ua 'Angiogenesis Inhibitors'. Cov tshuaj txawv txawv no hu ua dab tsi? Nws ua dab tsi tiag? Tsis txhob txhawj, cia peb tham txog nws yooj yim.
Ua ntej, cia peb saib, cov tshuaj angiogenesis inhibitors no yog dab tsi?
Hais yooj yim xwb, qhov no yog ib hom tshuaj uas tiv thaiv kev loj hlob ntawm cov hlab ntsha tshiab, uas yog cov hlab ntsha uas muab cov qog. Lwm lub npe rau qhov no yog cov tshuaj tiv thaiv angiogenics, cov tshuaj tiv thaiv angiogenic, thiab cov tshuaj tiv thaiv angiogenic.
Xav txog nws, rau txhua yam kom loj hlob, nws xav tau zaub mov, khoom noj khoom haus, puas yog? Cov qe ntshav qog nqaij hlav zoo li ntawd. Lawv kuj xav tau cov ntshav tas mus li uas muaj cov as-ham kom loj hlob thiab kis mus. Thaum cov qe ntshav qog nqaij hlav me me, nws tseem muaj sia nyob los ntawm kev nqus cov ntshav los ntawm cov nqaij noj qab nyob zoo nyob ib puag ncig nws. Tab sis thaum cov qe ntshav loj hlob mus txog li 1-2 millimeters, nws yuav tsum tsim nws cov hlab ntsha tshiab. Txwv tsis pub, nws yuav tsis loj hlob loj dua.
Qhov no yog qhov uas cov tshuaj hu ua Angiogenesis Inhibitors tuaj rau hauv. Cov tshuaj no ua haujlwm los ntawm kev thaiv cov txheej txheem uas cov hlwb qog nqaij hlav loj hlob cov hlab ntsha tshiab. Nws zoo li txiav cov dej mus rau tsob ntoo. Qhov no ua rau qeeb qeeb ntawm kev loj hlob ntawm cov qog nqaij hlav, thiab qee zaum cov qog nqaij hlav tuaj yeem me me. Kev kho mob no yuav tsis kho tau cov qog nqaij hlav tag nrho, tab sis nws tuaj yeem tswj kev loj hlob ntawm cov qog nqaij hlav thiab cia koj nyob nrog koj cov neeg hlub ntev me ntsis.
Cov tshuaj no ua haujlwm li cas hauv lub cev?
Cov tshuaj no cuam tshuam rau cov txheej txheem hu ua angiogenesis . Qhov no yog ib qho txheej txheem ib txwm muaj hauv peb lub cev. Xav txog yog tias koj txiav koj txhais tes, cov hlab ntsha tshiab yuav tsum loj hlob los kho qhov txhab thiab coj ntshav mus rau thaj chaw ntawd. Qhov ntawd hu ua angiogenesis. Cov hlwb raug mob xa tawm lub teeb liab, zoo li "Pab peb!" Lub teeb liab no ua rau cov hlab ntsha tshiab loj hlob.
Tiam sis qhov teeb meem yog, cov qog nqaij hlav kuj siv cov txheej txheem no rau lawv qhov kom zoo dua. Cov qog nqaij hlav kuj xa cov cim zoo sib xws thiab loj hlob cov hlab ntsha tshiab rau lawv tus kheej. Cov hlab ntsha no yog cov uas muab cov as-ham rau cov qog nqaij hlav uas nws xav tau, ua rau nws loj hlob thiab kis mus rau lwm qhov ntawm lub cev.
Cov tshuaj Angiogenesis Inhibitors ua haujlwm los ntawm kev cuam tshuam cov kab ke no los ntawm tus mob qog noj ntshav. Feem ntau ntawm cov tshuaj no ua haujlwm los ntawm kev thaiv cov protein hu ua vascular endothelial growth factor (VEGF) . Xav txog VEGF ua lub cim "pab" tseem ceeb uas cov hlwb qog noj ntshav tso tawm. Thaum lub cim VEGF no khi rau VEGF receptors ntawm cov hlwb qog noj ntshav, cov hlab ntsha tshiab pib tsim.
Tam sim no cia peb saib seb cov tshuaj no yuav ua li cas thiaj li tiv thaiv tau lub teeb liab no.
- Thaiv lub teeb liab VEGF kom tsis txhob khi rau lub receptor: Qee cov tshuaj (piv txwv li, cov tshuaj monoclonal antibodies xws li Bevacizumab (Avastin®) mus ncaj qha rau cov protein VEGF thiab txuas rau nws. Tom qab ntawd nws tsis tuaj yeem mus rau lub receptor ntawd thiab khi rau nws. Nws zoo li cuam tshuam ib tsab ntawv ua ntej nws mus txog tus neeg txais.
- Thaiv cov teeb liab los ntawm VEGF receptors: Qee cov tshuaj lwm yam (piv txwv li, tyrosine kinase inhibitors xws li sorafenib (Nexavar®) thiab sunitinib (Sutent®)) thaiv tus receptor los ntawm kev xa cov lus rov qab, txawm tias nws tau txais cov teeb liab los xij.
- Thaiv lwm cov kab ke ua haujlwm: Qee cov tshuaj lwm yam (piv txwv li, cov tshuaj immunomodulators xws li thalidomide thiab lenalidomide (Revlimid®)) cuam tshuam rau lwm cov kab ke ua haujlwm uas koom nrog hauv cov txheej txheem no.
Cov tshuaj no siv rau hom mob qog noj ntshav twg?
Cov kws kho mob feem ntau sau ntawv kom siv cov tshuaj angiogenesis inhibitors no rau cov mob qog nqaij hlav uas mob hnyav lossis rov tshwm sim dua . Qee hom mob qog nqaij hlav uas pom zoo kom siv cov tshuaj no yog:
- Mob qog nqaij hlav hauv hlwb
- Mob qog noj ntshav hauv lub mis
- Mob qog nqaij hlav ntawm lub tsev menyuam
- Mob qog nqaij hlav plab
- Mob qog nqaij hlav ntawm lub raj mis
- Mob qog nqaij hlav
- Mob qog nqaij hlav
- Mob qog nqaij hlav ntsws
- Lymphoma
- ntau yam mob myeloma
- Mob qog nqaij hlav pancreatic
- Mob qog nqaij hlav ntawm lub plab
- Mob qog noj ntshav hauv plab
- Mob qog nqaij hlav
- Mob qog nqaij hlav hauv tsev menyuam/endometrial
Ntxiv rau, cov tshuaj no (VEGF inhibitors) kuj tseem siv los kho qee yam kab mob qhov muag uas cov hlab ntsha loj hlob tsis zoo hauv lub qhov muag.
Muaj dab tsi tshwm sim thaum lub sijhawm kho mob?
Cov kws kho mob feem ntau tsis muab cov tshuaj no ib leeg xwb. Lawv feem ntau muab ua ke nrog lwm yam kev kho mob qog noj ntshav, xws li kev kho mob tiv thaiv kab mob thiab kev kho mob qog noj ntshav .
Xav txog nws zoo li kev ua tsov rog. Cov tshuaj Angiogenesis Inhibitors txiav cov khoom noj thiab cov mos txwv (ntshav) uas tus yeeb ncuab (mob qog noj ntshav) tau txais. Lwm yam kev kho mob (xws li chemotherapy) mus ncaj qha rau tus yeeb ncuab (cov hlwb qog noj ntshav) thiab tawm tsam lawv. Thaum ob txoj kev no ua haujlwm ua ke, cov txiaj ntsig tuaj yeem ua tiav ntau dua.
Nyob ntawm seb koj tau txais hom tshuaj dab tsi, tej zaum koj yuav tau noj nws ua ib lub tshuaj ib zaug lossis ob zaug hauv ib hnub, lossis koj yuav tau txais nws ua IV (xws li saline ) rau hauv cov leeg ntshav raws sijhawm.
Kev kho mob no yuav siv sijhawm ntev npaum li cas?
Qhov ntev ntawm koj txoj kev kho mob nyob ntawm ntau yam, suav nrog hom tshuaj uas koj tau txais thiab hom mob qog noj ntshav uas koj muaj. Cov neeg feem coob tseem noj cov tshuaj no ntev npaum li lawv ua haujlwm. Qee zaum, kev kho mob yuav raug tso tseg yog tias cov kev mob tshwm sim dhau los ua ntau dhau. Koj tus kws kho mob yuav tham txog cov txiaj ntsig thiab cov kev mob tshwm sim ntawm kev kho mob nrog koj thiab txiav txim siab zoo tshaj plaws.
Cov kev mob tshwm sim thiab kev pheej hmoo yog dab tsi?
Ib yam li lwm yam tshuaj, cov kev kho mob no tuaj yeem muaj cov kev mob tshwm sim thiab kev pheej hmoo. Feem ntau ntawm cov no yog teeb meem nrog kev los ntshav (los ntshav) thiab cov ntshav txhaws. Hauv qee kis tsis tshua muaj, cov kev mob tshwm sim no tuaj yeem ua rau tuag taus. Yog li nws yog ib qho tseem ceeb uas yuav tsum paub txog cov no.
Koj tus kws kho mob yuav saib xyuas koj txoj kev noj qab haus huv tas li kom txo cov kev pheej hmoo no.
| Tej zaum yuav muaj kev phiv/kev pheej hmoo | Piav qhia yooj yim |
|---|---|
| Ntshav siab | Ntshav siab. Qhov no yuav tsum tau kuaj xyuas thiab tswj tsis tu ncua. |
| Kev los ntshav sab hauv | Kev ntshav hauv lub cev. |
| Kev kho qhov txhab qeeb qeeb | Vim nws cuam tshuam rau kev tsim cov hlab ntsha tshiab, nws tuaj yeem ua rau lub sijhawm ntev dua rau cov qhov txhab kom kho. |
| Kev tawg ntawm txoj hnyuv plab | Tsis tshua muaj, muaj kev pheej hmoo ntawm kev tho lub plab lossis txoj hnyuv. |
| Txo qis kev ua haujlwm ntawm cov thyroid | Kev qeeb ntawm cov thyroid caj pas, uas tswj lub cev cov tshuaj hormones. |
| Kev puas tsuaj rau daim siab | Qee zaum kev ua haujlwm ntawm daim siab yuav raug cuam tshuam. |
| Cov ntshav txhaws | Muaj kev pheej hmoo ntawm cov ntshav txhaws uas ua rau muaj kev phom sij hauv cov hlab ntsha. Cov no tuaj yeem ua rau muaj mob xws li mob plawv nres lossis mob hlwb. |
Qhov tseem ceeb tshaj plaws uas koj ua tau yog nkag siab txog cov kev mob tshwm sim thiab kev pheej hmoo no ua ntej koj pib kho mob. Thaum koj paub tias yuav muaj dab tsi tshwm sim, koj tuaj yeem paub ntau ntxiv txog kev hloov pauv hauv koj lub cev. Yog tias koj pom muaj dab tsi txawv txawv, qhia rau koj tus kws kho mob paub tam sim ntawd. Tom qab ntawd nws tuaj yeem qhia koj yuav ua li cas tswj cov kev mob tshwm sim lossis kho koj cov tshuaj noj.
Puas muaj tej yam uas yuav ua rau qhov txheej txheem no tsis txhob muaj teeb meem?
Qhov no yog ib lo lus nug uas ntau tus neeg nug. Qee cov khoom noj muaj cov tshuaj uas thaiv qee cov cim qhia uas koom nrog hauv cov txheej txheem ntawm angiogenesis. Ntau yam ntawm cov khoom noj no pom muaj nyob rau hauv Mediterranean noj. Piv txwv li:
- Asparagus
- Cov hauv paus dandelion
- Tshuaj yej ntsuab
- Roj txiv roj
- Txiv laum huab xeeb
- Cawv liab
- Txiv hmab liab
Cov kws tshawb fawb kho mob tab tom sim siv cov tshuaj no los tsim cov tshuaj tshiab, tab sis kev tshawb fawb ntawd tseem nyob rau theem pib.
Tiamsis qhov tseem ceeb tshaj plaws uas yuav tsum nco ntsoov ntawm no yog tias cov khoom noj no yeej yuav tsis hloov tau cov tshuaj kho mob qog noj ntshav. Hauv lwm lo lus, noj ntau txiv hmab liab thiab haus tshuaj yej ntsuab yuav tsis tiv thaiv tau qog noj ntshav. Qhov ntawd yog lub tswv yim tsis raug kiag li.
Txawm li cas los xij, kev noj zaub mov zoo yog qhov tseem ceeb heev kom koj lub cev muaj zog. Nws yog ib qho tseem ceeb kom muab cov khoom noj khoom haus zoo rau lub cev thaum lub sijhawm thiab tom qab kev kho mob qog noj ntshav.
Thaum twg koj yuav tsum tau nrog kws kho mob tham?
Yog tias koj muaj cov tsos mob tsis tau xav txog thaum lub sijhawm kho mob, hu rau koj tus kws kho mob tam sim ntawd.
Tshwj xeeb tshaj yog tias koj pom cov cim qhia txog tus mob uas yuav ua rau tuag taus, xws li mob plawv nres lossis mob hlwb, mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) tam sim ntawd.
Cov tshuaj angiogenesis inhibitors yog ib qho kev kho mob tseem ceeb heev uas thaiv cov hlwb qog nqaij hlav kom tsis txhob kho peb lub cev. Tej zaum lawv yuav tsis kho tau tus mob qog nqaij hlav tag nrho, tab sis lawv tuaj yeem pab tswj nws txoj kev kis mus rau lwm qhov thiab muab sijhawm ntau rau koj ua neej nyob. Yog tias koj tus kws kho mob pom zoo kom siv cov tshuaj no, nco ntsoov nrog koj tus kws kho mob tham txog nws lub luag haujlwm hauv koj txoj kev npaj kho mob tag nrho.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cov Tshuaj Angiogenesis Inhibitors yog ib hom tshuaj uas tiv thaiv kev tsim cov hlab ntsha tshiab uas muab ntshav rau cov hlwb qog noj ntshav. Qhov no tiv thaiv cov hlwb qog noj ntshav kom tsis txhob tau txais cov as-ham uas lawv xav tau thiab tswj lawv txoj kev loj hlob.
- Txawm hais tias qhov no tsis kho tau tus mob qog noj ntshav tag nrho los xij, nws tuaj yeem tswj tau qhov kev kis tus kab mob thiab ua kom lub neej muaj sia nyob ntev dua.
- Kev kho mob no feem ntau muab ua ke nrog lwm yam kev kho mob, xws li chemotherapy.
- Nws yog ib qho tseem ceeb uas yuav tsum paub txog cov kev mob tshwm sim xws li ntshav siab, ntshav txhaws, thiab qhov txhab kho qeeb, thiab qhia rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txav.
- Txawm hais tias qee cov khoom noj ntuj muaj cov tshuaj uas cuam tshuam rau cov txheej txheem no, lawv yuav tsum tsis txhob siv los hloov kev kho mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus