Qee zaum, tom qab noj zaub mov ntsim, koj yuav hnov mob kub hnyiab hauv koj lub hauv siab, puas yog? Los yog koj puas xav tias tsis xis nyob zoo li koj cov kua qaub hauv plab tau nce ntxiv thiab tab tom nce mus rau hauv koj lub caj pas? Cov tshuaj H2 blockers yog ib hom tshuaj uas ntau tus neeg siv thaum lub sijhawm zoo li no. Yog li hnub no, cia peb tham txog cov tshuaj H2 blockers no yog dab tsi, lawv ua haujlwm li cas hauv peb lub cev, thiab cov yam tseem ceeb twg peb yuav tsum paub thaum siv lawv.
Cov H2 Blockers no yog dab tsi?
Hauv lwm lo lus, H2 blockers (tseem hu ua H2 antagonists) yog ib hom tshuaj uas tswj lossis txo cov kua qaub hauv koj lub plab.
Cov kua qaub hauv plab yog qhov tseem ceeb rau kev zom cov zaub mov uas peb noj. Tab sis yog tias muaj cov kua qaub no ntau dhau, nws tuaj yeem ua rau lub txheej ntawm koj txoj hnyuv plab puas tsuaj. Qhov no tuaj yeem ua rau muaj cov tsos mob xws li mob plab thiab mob siab. Nws tuaj yeem ua rau tsis xis nyob zoo li kev khuv xim rau pluas mov kawg uas koj noj.
Yog tias koj kuj tseem muaj kev tsis xis nyob vim muaj cov kua qaub ntau ntxiv hauv plab, koj yuav xav txog kev siv H2 blocker.
Cov tshuaj H2 blockers siv rau cov mob twg?
Cov tshuaj H2 blockers feem ntau yog siv los kho cov mob uas cuam tshuam nrog kev tsim cov kua qaub ntau dhau hauv plab. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov tshuaj no tuaj yeem maj mam poob lawv cov txiaj ntsig yog tias siv tas li rau lub sijhawm ntev.
Yog koj muaj mob ntev, koj tus kws kho mob yuav pom zoo kom siv hom tshuaj hu ua Proton Pump Inhibitor (PPI) es tsis txhob siv H2 blockers. Txawm hais tias PPIs siv sijhawm ntev dua los ua haujlwm, lawv tuaj yeem tswj cov kua qaub ntau dua li H2 blockers. Lawv kuj tseem siv tau ntev.
Qee qhov mob tseem ceeb uas kho nrog H2 blockers tau teev tseg hauv qab no.
| Mob nkeeg | Ib qho lus piav qhia yooj yim |
|---|---|
| Mob plab | Cov kua qaub ntau dhau uas tsim tawm tuaj yeem ua rau lub plab puas tsuaj thiab ua rau mob qog. Kev txo cov kua qaub nrog H2 blockers muab sijhawm thiab ib puag ncig rau cov qog uas lawv xav tau los kho. |
| Cov kab mob duodenal | Cov kua qaub hauv plab tuaj yeem mus rau hauv thawj ntu ntawm txoj hnyuv me (duodenum) thiab ua rau muaj qhov txhab nyob ntawd. Qhov mob no kuj tuaj yeem kho nrog H2 blockers, txawm hais tias PPIs zoo dua. |
| kua qaub rov qab los | Cov kua qaub hauv plab rov qab mus rau hauv txoj hlab pas thiab caj pas, ua rau mob plab. Qhov no kuj tuaj yeem ua rau mob plab. Tshuaj H2 blocker yog ib qho kev daws teeb meem zoo rau qhov mob no. Tab sis yog tias qhov no tshwm sim ntau zaus (GERD), PPI yog qhov tsim nyog dua. |
| Zollinger-Ellison syndrome | Qhov no yog ib qho mob tsis tshua muaj. Qee cov qog nqaij hlav uas tsim nyob rau hauv qhov mob no ua rau lub plab tsim cov kua qaub ntau dhau. Txawm hais tias H2 blockers tuaj yeem pab tswj qhov mob no, cov kws kho mob feem ntau pom zoo kom siv PPIs. |
Cov tshuaj H2 blockers pab txo cov tsos mob hauv qab no uas cuam tshuam nrog cov mob no:
- Kev zom zaub mov tsis zoo
- Mob plab
- Mob hauv siab thiab mob caj pas
- Xeev siab thiab ntuav
- Mob plab
Cov tshuaj no ua haujlwm li cas hauv lub cev?
Nws yooj yim heev. Lwm lub npe rau H2 blockers yog histamine-2 (H2) antagonists. Peb tau kawm hauv tsev kawm ntawv tias 'antagonist' hauv zaj dab neeg yog ib yam dab tsi uas cuam tshuam rau ib yam dab tsi? Zoo, qhov uas cov H2 antagonists no ua yog cuam tshuam rau cov txheej txheem ntawm kev tsim cov kua qaub hauv plab.
Xav txog nws li no. Tom qab peb noj mov, peb lub cev tso tawm ib yam tshuaj hu ua H2. Cov H2 no mus thiab txuas rau cov H2 receptors ntawm phab ntsa ntawm lub plab. Nws zoo li tus yuam sij haum rau hauv lub xauv. Qhov txuas no yog qhov qhia rau lub plab, "Okay, tam sim no ua kua qaub."
Thaum koj noj tshuaj H2 blocker, cov tshuaj yuav mus thiab khi rau cov H2 receptors (cov xauv) thiab "block" lawv. Ua li ntawd, H2 (cov yuam sij) yuav tsis muaj sijhawm los khi rau cov receptors. Thaum lub teeb liab kom tsim cov kua qaub tsis ua haujlwm lawm, lub plab yuav tsim cov kua qaub tsawg dua.
Qhov no tsis cuam tshuam rau koj txoj kev zom zaub mov. Nws tsuas yog tswj cov kua qaub ntau ntxiv uas tsim tawm uas ua rau mob thiab tsis xis nyob.
Muaj cov tshuaj H2 blocker twg?
Muaj ntau hom tshuaj H2 blockers. Qee hom tuaj yeem yuav tau yam tsis tas yuav muaj daim ntawv yuav tshuaj (OTC), thaum lwm hom yuav tsum tau daim ntawv yuav tshuaj los ntawm kws kho mob.
| Lub npe ntawm cov tshuaj | Ib hom lag luam uas pom ntau zaus | Yuav ua li cas thiaj tau txais nws |
|---|---|---|
| Cimetidine | Tagamet® | Kev yuav tshuaj uas tsis tas yuav muaj ntawv yuav tshuaj thiab daim ntawv yuav tshuaj (OTC & Rx) |
| Famotidine | Pepcid® | Kev yuav tshuaj uas tsis tas yuav muaj ntawv yuav tshuaj thiab daim ntawv yuav tshuaj (OTC & Rx) |
| Nizatidine | Axid® | Tsuas yog raws li daim ntawv qhia ntawm kws kho mob xwb (Rx xwb) |
Lus Cim Tshwj Xeeb: Tej zaum koj yuav nco qab H2 blocker Ranitidine (Zantac®) uas ib zaug nrov heev. Tab sis thaum lub Plaub Hlis Ntuj xyoo 2020, cov koom haum xws li FDA (US Food and Drug Administration) tau hais kom cov chaw tsim khoom tshem tawm cov tshuaj no ntawm kev ua lag luam. Qhov laj thawj yog vim tias kev sim qhia tau tias dhau sijhawm thiab thaum khaws cia rau qhov kub siab, cov tshuaj hu ua nitrosodimethylamine, lossis NDMA, uas yog cov kab mob carcinogen, nce mus rau qib tsis muaj kev nyab xeeb.
Yuav tsum siv cov tshuaj no li cas thiab thaum twg?
Cov tshuaj H2 blockers noj tau los ntawm qhov ncauj ua cov tshuaj ntsiav lossis cov tshuaj ntsiav. Kuj tseem muaj cov hmoov uas tuaj yeem yaj rau hauv cov kua rau cov neeg uas muaj teeb meem nqos cov tshuaj. Lawv kuj tseem tuaj yeem muab cov tshuaj txhaj rau hauv cov hlab ntsha (IV) rau cov neeg mob uas nyob hauv tsev kho mob thiab tsis tuaj yeem noj tshuaj.
Lub sijhawm zoo tshaj plaws los noj tshuaj
- Rau qee lub sijhawm tsis xis nyob:Yog koj paub tias kev noj cov khoom noj ntsim los yog cov khoom noj uas muaj roj ntau ua rau koj muaj teeb meem, noj tshuaj H2 blocker 30 txog 60 feeb ua ntej noj cov khoom noj ntawd. Qhov ntawd yuav ua rau nws muaj sijhawm ua haujlwm. Nws tsis ua li cas rau kev noj nws tom qab qhov teeb meem pib, tab sis nws yuav siv sijhawm txog li ib teev kom cov tsos mob ploj mus.
- Rau ib qho mob xws li qhov txhab zoo: Koj tus kws kho mob yuav pom zoo kom noj nws ib zaug ib hnub ua ntej pw, lossis ib zaug thaum sawv ntxov thiab ib zaug thaum hmo ntuj, nyob ntawm koj tus kws kho mob cov lus qhia.
Qhov tseem ceeb tshaj plaws yog tias yog koj xav siv cov tshuaj no ntau tshaj ob lub lis piam ib zaug, koj yuav tsum mus ntsib koj tus kws kho mob. Nws tsis zoo rau koj txuas ntxiv siv cov no yam tsis tau nrhiav pom qhov ua rau koj cov tsos mob.
Qhov txawv ntawm H2 Blockers, Antacids thiab PPIs yog dab tsi?
Muaj coob tus neeg tsis meej pem txog peb hom tshuaj no uas siv rau mob plab. Cia peb saib seb qhov txawv tseem ceeb ntawm lawv yog dab tsi.
| Hom tshuaj | Lub sijhawm siv los ua haujlwm | Lub sijhawm ntawm cov nyhuv | Lub cib fim zoo tshaj plaws |
|---|---|---|---|
| Cov tshuaj Antacids (piv txwv li Digene, Gelusil) | Sai heev (ob peb feeb) | Luv heev (1-2 teev) | Thaum xav tau kev pab tam sim ntawd. |
| Cov tshuaj thaiv H2 | Kwv yees li ib teev | Kwv yees li 4-10 teev | Txhawm rau tiv thaiv kev mob plab qee zaum lossis ua ntej noj mov. |
| Cov Tshuaj PPIs (Proton Twj Tso Kua Mis) | 1-4 hnub rau tag nrho cov txiaj ntsig | Lub sijhawm ntev (24 teev+) | Rau cov mob xws li mob gastritis ntev thiab GERD. |
Puas muaj tej yam tshwm sim tsis zoo?
Cov tshuaj H2 blockers feem ntau yog cov tshuaj muaj kev nyab xeeb heev nrog ob peb qhov kev phiv . Txawm tias muaj cov kev phiv tshwm sim los xij, feem ntau lawv tsis muaj teeb meem dab tsi.
- Mob plab
- Mob nqaij
- Kab mob cem quav
- Mob raws plab
- Qhov ncauj qhuav
- Kev qaug zog
- Mob taub hau
Tsis tshua muaj neeg mob, cov neeg uas muaj feem yuav mob hnyav (tshwj xeeb tshaj yog cov neeg hnub nyoog tshaj 50 xyoo, cov neeg uas muaj teeb meem raum lossis siab) yuav muaj cov tsos mob ntsig txog lub paj hlwb, xws li tsis nco qab lossis hais lus tsis tau zoo. Txawm li cas los xij, qhov no tsis tshua muaj neeg mob . Cov tsos mob no feem ntau yuav ploj mus li ob peb hnub tom qab tso tseg cov tshuaj.
Kev sib cuam tshuam nrog lwm cov tshuaj
Qee cov tshuaj H2 blockers tuaj yeem cuam tshuam rau txoj kev uas lwm cov tshuaj uas koj noj ua haujlwm. Piv txwv li, cov tshuaj H2 blocker cimetidine tuaj yeem txo qhov ua tau zoo ntawm qee cov tshuaj antidepressants (SSRIs) thiab cov tshuaj warfarin uas ua rau cov ntshav nyias.
Yog li ntawd, ua ntej koj pib siv H2 blocker tshiab, nws yog ib qho tseem ceeb heev uas yuav tsum qhia rau koj tus kws kho mob txog txhua yam tshuaj uas koj twb noj lawm.
Cov no puas haum rau cov niam cev xeeb tub thiab cov niam pub niam mis?
Tseem xav tau kev tshawb fawb ntxiv txog kev nyab xeeb ntawm kev siv H2 blockers thaum cev xeeb tub, tab sis nws paub tias cov tshuaj no hla mus rau tus menyuam los ntawm mis niam.
Yog li ntawd, yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis yog niam uas pub niam mis rau menyuam, nco ntsoov nrog koj tus kws kho mob tham ua ntej noj cov tshuaj no.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cov tshuaj H2 blockers yog ib hom tshuaj uas txo cov kua qaub hauv plab. Lawv zoo heev rau kev pab kom tsis txhob mob plab thiab mob hauv siab ib ntus.
- Txawm hais tias cov no ua haujlwm sai dua li PPIs, lawv tsis haum rau kev siv mus sij hawm ntev, txhua hnub.
- Yog tias koj xav tau siv cov tshuaj H2 blockers ntau tshaj ob lub lis piam ib zaug, nws txhais tau tias koj muaj lwm yam teeb meem hauv qab no. Mus ntsib kws kho mob kom sai.
- Qhia rau koj tus kws kho mob txog lwm yam tshuaj uas koj noj (txawm tias cov vitamins).
- Yog tias koj cev xeeb tub lossis pub niam mis, tsis txhob siv cov tshuaj no yam tsis tau kev qhia los ntawm kws kho mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus