Thaum peb paub tias peb niam, peb txiv, lossis ib tug neeg uas nyob ze peb heev muaj tus kab mob Alzheimer's, peb tu siab thiab txhawj xeeb heev. Nws nyuaj heev rau pom lawv lub cim xeeb ploj mus thiab lawv tsis nco qab tej yam. Tab sis tsis txhob txhawj. Txawm hais tias tsis muaj kev kho rau tus kab mob no, muaj ntau hom tshuaj uas tuaj yeem pab tswj cov tsos mob, qeeb qeeb qhov kev loj hlob ntawm tus kab mob, thiab ua rau lawv lub neej yooj yim dua me ntsis. Hnub no, peb yuav tham txog cov tshuaj ntawd.
Muaj dab tsi tshwm sim rau lub hlwb hauv tus kab mob Alzheimer?
Ua ntej peb tham txog cov tshuaj no, cia peb nkag siab yooj yim txog qhov tshwm sim rau lub hlwb hauv tus kab mob Alzheimer. Cov lus tau sib pauv ntawm cov hlwb hlab ntsha hauv peb lub hlwb los ntawm cov tshuaj lom neeg. Hauv tus kab mob Alzheimer, cov protein tsis zoo (amyloid thiab tau) pib sib sau ua ke hauv lub hlwb. Qhov no ua rau cov hlwb hlab ntsha puas tsuaj thiab cuam tshuam kev sib txuas lus ntawm lawv. Qhov no muaj kev cuam tshuam loj rau cov feem ntawm lub hlwb uas tswj kev nco, kev xav, thiab tus cwj pwm .
Cov tshuaj tam sim no feem ntau tswj cov txheej txheem no. Qee cov tshuaj ua kom cov tshuaj xa mus rau lub hlwb sib npaug, thaum cov tshuaj tshiab sim tshem tawm cov protein uas tsis zoo.
Cov tshuaj tseem ceeb rau tus kab mob Alzheimer
Cov tshuaj kho mob Alzheimer's muaj ob pawg tseem ceeb. Ib qho yog cov tshuaj uas tswj cov tsos mob. Qhov thib ob yog cov tshuaj tshiab uas sim tswj qhov kev loj hlob ntawm tus kab mob, uas yog, qhov kev hnyav zuj zus ntawm tus kab mob.
1. Cov Tshuaj Cholinesterase Inhibitors
Cov no yog cov tshuaj uas feem ntau muab rau cov neeg mob uas nyob rau theem pib thiab theem nrab ntawm tus kab mob Alzheimer.
Lawv ua haujlwm li cas?
Hais yooj yim xwb, peb lub hlwb muaj ib tug neeg xa xov hu ua acetylcholine , uas yog qhov tseem ceeb rau tej yam xws li kev nco thiab kev kawm. Hauv tus kab mob Alzheimer, cov theem ntawm acetylcholine no txo qis. Cov tshuaj no ua yog tiv thaiv kev tawg ntawm acetylcholine hauv lub hlwb. Qhov no tso cai rau cov lus xa mus ntawm cov hlwb hlwb zoo dua me ntsis.
Cov tshuaj no tsis kho tau tus kab mob. Tab sis lawv tuaj yeem ncua qhov kev mob zuj zus mus li 6 txog 12 lub hlis. Rau qee tus neeg mob, lawv tuaj yeem txhim kho lawv txoj kev mloog, kev nco, thiab kev muaj peev xwm ua haujlwm txhua hnub.
| Lub npe ntawm cov tshuaj | Cov xwm txheej siv | Yuav muab li cas |
|---|---|---|
| Donepezil | Rau txhua theem ntawm tus kab mob | Ib lub tshuaj noj ib zaug ib hnub |
| Rivastigmine | Rau tsev kawm ntawv theem pib thiab theem nrab | Ib lub tshuaj noj ob zaug ib hnub los yog ib daim tawv nqaij |
| Galantamine | Rau tsev kawm ntawv theem pib thiab theem nrab | Cov ntsiav tshuaj/kua haus ib zaug lossis ob zaug hauv ib hnub |
Cov kev mob tshwm sim ntawm cov no yog dab tsi?
Tsis yog txhua tus neeg yuav muaj cov kev mob tshwm sim, tab sis qee tus neeg yuav xeev siab, ntuav, mob plab, o, thiab qaug zog.
2. Memantine
Cov tshuaj no feem ntau yog muab rau cov neeg uas muaj tus kab mob theem nrab mus rau theem hnyav. Qee zaum, tus kws kho mob yuav muab nws ua ke nrog Donepezil uas tau hais los saum toj no.
Nws ua haujlwm li cas?
Muaj lwm yam tshuaj lom neeg hauv lub hlwb hu ua glutamate uas siab dhau thaum muaj tus kab mob Alzheimer's. Qhov no tuaj yeem ua rau cov hlwb puas tsuaj. Memantine ua haujlwm los ntawm kev tswj cov glutamate no. Qhov no tuaj yeem pab txhim kho tus neeg mob txoj kev mloog, kev xav, thiab kev hais lus. Nws kuj tseem tuaj yeem pab tswj cov tsos mob xws li tsis nyob twj ywm, chim siab, thiab pom/hnov tej yam uas tsis muaj .
Cov kev mob tshwm sim: Tej zaum yuav muaj cem quav, kiv taub hau, mob taub hau, thiab tsaug zog.
3. Cov tshuaj tshiab uas tsom mus rau cov amyloid deposits hauv lub hlwb
Cov no yog cov kev tshawb pom tshiab kawg hauv kev kho mob Alzheimer's. Cov no yog cov tshuaj tshwj xeeb hu ua "monoclonal antibodies." Cov no ncaj qha tsom mus rau cov protein deposits hu ua amyloid plaques uas sib sau ua ke hauv lub hlwb. Lawv raug muab los ntawm cov leeg ntshav (IV). Tam sim no lawv tsuas yog pom zoo rau cov neeg mob uas nyob rau theem pib ntawm tus kab mob.
- Lecanemab (Leqembi)
- Donanemab (Kisunla)
Cov tshuaj no tau pom tias ua rau tus kab mob qeeb zuj zus. Txawm li cas los xij, lawv tuaj yeem ua rau muaj kev phiv tshuaj xws li lub hlwb o ib ntus lossis los ntshav me me, yog li lawv yuav tsum tau muab ua tib zoo thiab tsuas yog nyob rau hauv kev saib xyuas ze ntawm tus kws kho mob.
Tej yam koj yuav tsum paub thaum muab tshuaj rau tus neeg mob
Ua ib tug neeg saib xyuas ib tug neeg uas muaj Alzheimer's, koj muaj lub luag haujlwm loj heev, tshwj xeeb tshaj yog muab lawv cov tshuaj rau lawv raws sijhawm. Muaj ob peb yam uas koj yuav tsum paub txog.
Thaum ntxov ntawm tus kab mob:
Txawm hais tias tus neeg mob yuav noj tau tshuaj ntawm lawv tus kheej thaum pib los xij, lawv yuav maj mam tsis nco qab txog nws. Ua cov no los pab lawv.
- Siv lub thawv ntim tshuaj: Khaws koj cov tshuaj kom zoo rau lub lim tiam. Zoo tshaj plaws yog muaj ib lub uas muaj ntu rau sawv ntxov, tav su, thiab yav tsaus ntuj.
- Nco ntsoov koj tus kheej raws sijhawm: Teem lub tswb ceeb toom rau ntawm koj lub xov tooj. Los yog, yog tias koj ua tau, hu xov tooj thiab nco ntsoov koj tus kheej thaum lub sijhawm ntawd.
- Tham nrog lawv: Nug lawv nrog kev hlub, "Kuv puas tuaj yeem pab koj mus yuav koj cov tshuaj?" Pab lawv thaum hwm lawv txoj kev ywj pheej.
Thaum tus kab mob hnyav heev:
Nyob rau lub sijhawm ntev, koj yuav tsum lav ris tag nrho lub luag haujlwm rau kev muab tshuaj.
- Yog tias koj muaj teeb meem nqos cov tshuaj: Tej zaum yog vim koj lub qhov ncauj qhuav. Muab dej rau koj tus menyuam haus ua ntej muab tshuaj rau lawv. Tab sis yog tias qhov ntawd tsis ua haujlwm, nug koj tus kws kho mob seb cov tshuaj puas tuaj yeem zom thiab sib xyaw nrog zaub mov, lossis nws puas muaj nyob rau hauv daim ntawv kua. Tsis yog txhua yam tshuaj zoo rau zom , yog li nco ntsoov nug koj tus kws kho mob.
- Yog tias lawv hais tias lawv noj tsis tau cov tshuaj: Tsis txhob sib ntaus nrog lawv. Qhov ntawd tsuas yog yuav ua rau lawv chim siab ntxiv xwb. Thaum ntawd, tsum tsis txhob noj, tos ib pliag, thiab sim dua. Tej zaum lawv yuav noj yog tias koj maj mam ceeb toom lawv, "Nov yog cov tshuaj rau koj qhov teeb meem." Yog tias lawv tseem tsis kam, qhia rau koj tus kws kho mob.
- Khaws ib daim ntawv teev cov tshuaj: Sau txhua yam tshuaj, cov vitamin, thiab cov tshuaj uas lawv noj, thiab thaum twg lawv noj. Nqa daim ntawv teev cov tshuaj no nrog koj thaum koj mus ntsib kws kho mob.
- Khaws koj cov tshuaj kom zoo: Khaws tag nrho cov tshuaj rau hauv lub txee xauv, kom deb ntawm cov menyuam yaus thiab tus neeg mob.
Qhov tseem ceeb tshaj plaws yog, tsis txhob tsum noj tshuaj uas koj tus kws kho mob tau sau tseg lossis hloov qhov ntau npaum li cas yam tsis tau nug nws ua ntej. Yog tias koj muaj teeb meem dab tsi, mus ntsib koj tus kws kho mob tam sim ntawd.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Txawm hais tias tus kab mob Alzheimer's tsis tuaj yeem kho tau tag nrho los xij, muaj cov tshuaj uas tuaj yeem tswj cov tsos mob thiab qeeb qhov kev loj hlob ntawm tus kab mob.
- Cov tshuaj muaj peev xwm muab faib ua ob pawg tseem ceeb: cov uas tswj cov tsos mob (Cholinesterase inhibitors, Memantine) thiab cov tshuaj tshiab dua uas sim hloov txoj kev mob (Monoclonal antibodies).
- Koj tus kws kho mob yuav txiav txim siab seb cov tshuaj twg zoo tshaj plaws rau koj tus neeg hlub, nyob ntawm theem ntawm tus kab mob thiab tus neeg mob tus mob.
- Koj lub luag haujlwm hauv kev muab tshuaj thiab kev saib xyuas tus neeg mob yog qhov tseem ceeb heev. Nws yog ib qho tseem ceeb uas yuav tsum ua siab ntev, muaj kev hlub, thiab ua raws li cov lus qhia ntawm kws kho mob.
- Yog koj pom muaj teeb meem lossis cov kev mob tshwm sim ntsig txog koj cov tshuaj, nrog koj tus kws kho mob tham tam sim ntawd.











💬 Comments (0)
Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus