Mob taub hau migraine uas zoo li koj lub taub hau yuav tawg, teeb pom kev tshwm sim ua ntej koj lub qhov muag, thiab koj xav tias koj yuav ntuav ... Koj puas paub txog qhov kev paub no? Qee zaum koj yuav tsum nyob hauv chav tsaus ntuj, ntsiag to thoob plaws hnub, puas yog? Mob taub hau migraine tsis yog mob taub hau xwb, nws yog ib yam dab tsi uas tsuas yog tus neeg uas muaj nws paub. Yog li hnub no peb yuav tham txog ib hom tshuaj tseem ceeb heev uas siv los kho mob taub hau migraines. Ntawd yog Triptans.
Triptans yog dab tsi?
Hais yooj yim xwb, Triptans yog ib hom tshuaj uas muab rau kom tsis txhob mob taub hau thaum nws pib mob . Lawv suav hais tias yog thawj kab kev kho mob rau mob taub hau. Feem ntau, cov tshuaj no tsis tiv thaiv mob taub hau, tab sis lawv tuaj yeem pab tswj qhov mob thiab lwm yam tsos mob thaum nws pib mob .
Kab mob migraine tsis yog tsuas yog mob taub hau xwb. Nws yog ib qho mob hlwb uas cuam tshuam rau peb lub hlwb. Qhov no yog vim li cas, ntxiv rau mob taub hau, muaj tej yam xws li kev hloov pauv ntawm qhov muag pom, pom teeb pom kev zoo nyob rau pem hauv ntej ntawm peb lub qhov muag (aura), xeev siab, ntuav, thiab rhiab rau lub teeb thiab suab. Rau qee tus, cov tsos mob no hnyav heev uas lawv ua tsis tau dab tsi tsuas yog pw hauv qhov chaw tsaus ntuj thiab ntsiag to kom txog thaum mob migraine tas.
Cov tshuaj Triptans, uas tau tshawb pom hauv xyoo 1980, tau hloov pauv txoj kev kho mob migraines. Thawj cov tshuaj triptan, '(Sumatriptan),' tau tsim tawm hauv xyoo 1990. Muaj ntau lwm cov tshuaj triptans tau tsim tawm tom qab.
Muaj hom triptans dab tsi?
Tam sim no muaj xya hom tshuaj triptans. Tag nrho cov tshuaj no kho mob taub hau, tab sis qee cov tshuaj tau pom zoo rau cov hom mob taub hau tshwj xeeb thiab siv rau cov menyuam yaus thiab cov hluas. Txoj hauv kev yooj yim tshaj plaws los txheeb xyuas cov tshuaj no yog nrhiav cov lus "-triptan" tom qab lawv lub npe.
Lub rooj hauv qab no teev cov hom triptans thiab yuav ua li cas thiaj tau txais lawv.
| Lub Npe Tshuaj Triptan | Yuav ua li cas thiaj tau txais (Daim Ntawv) |
|---|---|
| Almotriptan | Tshuaj ntsiav noj |
| Eletriptan | Tshuaj ntsiav noj |
| Frovatriptan | Tshuaj ntsiav noj |
| Naratriptan | Tshuaj ntsiav noj |
| Rizatriptan | Tshuaj ntsiav noj |
| Sumatriptan | Haus, Tshuaj tsuag rau qhov ntswg/hmoov, Tshuaj txhaj rau hauv daim tawv nqaij |
| Zolmitriptan | Cov ntsiav tshuaj noj, tshuaj tsuag rau qhov ntswg |
Cov tshuaj no hu ua Triptans ua haujlwm li cas tiag?
Yuav kom nkag siab tias cov tshuaj no ua haujlwm li cas, peb yuav tsum nkag siab me ntsis txog seb peb hnov mob li cas thiab mob taub hau migraines tshwm sim li cas.
Cia peb los saib seb peb mob li cas.
Xav txog tias koj ntaus koj tus ntiv tes qhov twg. Qhov mob tsis yog tus ntiv tes hnov. Cov hlab ntsha hauv tus ntiv tes xa ib lub teeb liab mus rau lub hlwb hais tias, "Muaj ib yam dab tsi mob ntawm no." Lub hlwb txhais lub teeb liab ntawd ua "mob" thiab ua rau koj hnov.
Peb lub hlwb tsis muaj cov hlab ntsha uas hnov mob, yog vim li cas cov kws tshawb fawb tseem tsis tau nkag siab tag nrho tias mob taub hau migraines tshwm sim li cas. Tab sis tam sim no lawv tau tshawb pom ntau txoj hauv kev uas yuav ua rau qhov no.
Zaj dab neeg tom qab mob migraines
Nws ntseeg tau tias peb yam tseem ceeb ua rau muaj mob migraines:
1. Kev ua haujlwm ntawm cov neuron: Peb lub hlwb, cov hlab ntsha caj qaum, thiab cov hlab ntsha yog tsim los ntawm cov hlwb hu ua neurons. Thaum muaj mob taub hau migraine, qee cov neurons hauv lub hlwb ua haujlwm hauv ib txoj kev tshwj xeeb. Qhov kev ua haujlwm ntawm lub hlwb no yog qhov ua rau peb hnov mob thiab lwm yam tsos mob ntawm mob taub hau migraine.
2. Kev Hloov Pauv ntawm Cov Ntshav: Thaum muaj mob taub hau migraine, cov hlab ntsha hauv lub hlwb yuav nqaim thiab nthuav dav. Qhov no ua rau cov ntshav ntws hloov pauv. Vim tias cov tshuaj triptans cuam tshuam rau cov hlab ntsha no, qhov no kuj xav tias yog ib qho ua rau mob taub hau migraines.
3. Kev o:Kev o yog ib qho txheej txheem uas peb lub cev siv los tiv thaiv thiab kho nws tus kheej. Kuj tau pom tias cov tshuaj uas ua rau o raug tso tawm thaum muaj mob taub hau.
Cov tshuaj triptans cuam tshuam li cas rau cov txheej txheem no?
Tam sim no cia peb saib seb Triptans cuam tshuam li cas rau qhov no. Cov hlwb ntawm peb lub paj hlwb txuas nrog ib leeg los ntawm cov tshuaj hu ua neurotransmitters. Cov no zoo li cov yuam sij. Cov hlwb paj hlwb muaj cov khoom hu ua receptors. Cov no zoo li cov yuam sij. Thaum tus yuam sij sab xis (neurotransmitter) txuas rau tus yuam sij sab xis (receptor), lub hlwb yuav ua haujlwm.
Cov tshuaj Triptans ua haujlwm los ntawm kev ua raws li cov neurotransmitter serotonin hauv lub hlwb. Qhov no txhais tau tias cov tshuaj no khi thiab ua kom cov receptors rau serotonin ua haujlwm. Lawv feem ntau cuam tshuam rau peb hom receptors:
- 5HT1B receptors: Cov no pom muaj nyob rau hauv cov hlab ntsha ntawm lub hlwb. Thaum triptans ua kom cov receptors no ua haujlwm, cov hlab ntsha uas tau nthuav dav tsis tsim nyog vim yog mob taub hau migraines yuav nqaim. Qhov no txo qhov mob.
- 5HT1D receptors: Cov no nyob hauv lub paj hlwb "Trigeminal", uas koom nrog peb txoj kev hnov mob. Thaum triptans ua kom cov no ua haujlwm, lawv txwv tsis pub tso cov tshuaj ua rau mob.
- 5HT1F receptors: Cov no kuj pab txwv tsis pub xa cov cim qhia mob mus rau lub hlwb.
Hais yooj yim xwb, cov tshuaj triptans ua haujlwm los ntawm kev so cov hlab ntsha hauv lub hlwb, thaiv kev tso tawm cov tshuaj ua rau mob, thiab txo qhov kev xa cov cim qhia mob mus rau lub hlwb. Tag nrho peb yam no pab tswj cov tsos mob ntawm mob taub hau.
Cov txiaj ntsig ntawm kev siv Triptans yog dab tsi?
Cov tshuaj Triptans muaj ntau qhov zoo dua li cov tshuaj migraine yav dhau los.
- Cov kev mob tshwm sim tsawg dua: Triptans muaj cov kev mob tshwm sim tsawg dua li cov tshuaj qub, thiab lawv tsis hnyav npaum li.
- Tsis ua rau yus quav tshuaj: Qee cov tshuaj tua mob rau mob taub hau, tshwj xeeb yog cov tshuaj opioid, tuaj yeem ua rau yus quav tshuaj. Txawm li cas los xij, cov tshuaj triptans tsis ua rau yus quav tshuaj.
- Muaj Kev Nyab Xeeb Heev: Cov tshuaj Triptans feem ntau yog cov tshuaj uas muaj kev nyab xeeb heev. Cov tshuaj xws li '(Sumatriptan)' muaj kev nyab xeeb heev uas nyob rau hauv qee lub tebchaws lawv tuaj yeem yuav tau ntawm lub txee ntawm lub tsev muag tshuaj yam tsis tas yuav muaj daim ntawv qhia los ntawm kws kho mob.
- Muaj ntau hom tshuaj sib txawv: Raws li peb tau pom hauv lub rooj dhau los, cov no tuaj yeem tau txais ntau hom tshuaj xws li tshuaj ntsiav, tshuaj tsuag qhov ntswg, thiab tshuaj txhaj. Tshuaj tsuag qhov ntswg yooj yim dua rau ib tus neeg uas muaj teeb meem nqos tshuaj lossis ntuav.
Puas muaj tej yam tsis zoo, tej yam tshwm sim, thiab tej yam teeb meem?
Ib yam li lwm yam tshuaj, Triptans muaj qee cov kev mob tshwm sim thiab tej yam uas yuav tsum paub.
Qhov tsis zoo ntawm Triptans
Qhov tsis zoo tshaj plaws yog tias lawv tsis tiv thaiv tau mob taub hau migraines . Lawv siv los ua tshuaj cawm kom "txwv" mob taub hau migraines tom qab nws pib mob. Txawm li cas los xij, muaj ib qho tshwj xeeb, thiab qhov ntawd yog mob taub hau migraines thaum muaj hli. Qee cov tshuaj triptans tuaj yeem pab tiv thaiv mob taub hau migraines yog tias noj li ob hnub ua ntej koj lub hli. Koj tus kws kho mob yuav qhia koj txog qhov no.
Lwm yam yog tias nws tsis zoo siv lawv ntau dhau . Ib txhia neeg xav tau ntau tshaj ib koob tshuaj kom txo tau qhov mob taub hau migraines. Txawm li cas los xij, yog tias koj noj Triptans ntau dhau, lawv cov txiaj ntsig yuav txo qis. Tsis yog li ntawd xwb, tab sis koj kuj tuaj yeem tau txais "mob taub hau siv tshuaj ntau dhau" vim yog siv tshuaj ntau dhau. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum siv cov no tsuas yog hauv qhov ntau npaum li cas thiab zaus uas tau teev tseg, raws li tus kws kho mob hais .
Cov kev mob tshwm sim feem ntau
Txawm hais tias tsis yog txhua tus neeg tau txais cov kev mob tshwm sim no thaum noj triptans, qee tus neeg yuav muaj lawv.
| Cov teebmeem sab | Kev piav qhia |
|---|---|
| kiv taub hau | kiv taub hau |
| Kev tsaug zog los yog qaug zog | Kev tsaug zog los yog qaug zog |
| Xeev siab | Xeev siab |
| Kev khaus khaus ntawm tes thiab taw | Kev khaus lossis loog ntawm tes/taw '(Paresthesia)' |
| Mob caj dab | Mob caj dab |
| Mob hauv siab (tsis tshua muaj) | Mob hauv siab (tsis tshua muaj) |
Thaum twg koj yuav tsum tsis txhob noj triptans?
Cov tshuaj Triptans tsis haum rau cov neeg uas muaj tej yam mob nkeeg (Contraindications).
- Kev Sib Cuam Tshuam Nrog Lwm Cov Tshuaj: Yog tias koj noj lwm cov tshuaj uas muaj "Ergotamine" rau mob taub hau lossis rau lwm yam mob, lawv yuav sib cuam tshuam nrog Triptans. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum qhia rau koj tus kws kho mob txog txhua yam tshuaj, cov vitamins, thiab cov tshuaj ntxiv uas koj noj .
- Kab mob plawv lossis teeb meem ntawm cov ntshav ncig: Cov tshuaj Triptans tsis haum rau koj yog tias koj muaj kab mob plawv, ntshav siab tsis tuaj yeem tswj tau (ntshav siab), lossis kab mob ntawm cov hlab ntsha. Cov kws kho mob kuj tsis pom zoo kom siv cov tshuaj no yog tias koj tau muaj lossis muaj feem yuav muaj kab mob plawv dhia tsis zoo, mob plawv nres, mob hlwb, lossis TIAs.
- Cev Xeeb Tub thiab Pub Niam Mis: Yog tias koj cev xeeb tub, tab tom sim cev xeeb tub, lossis pub niam mis, koj yuav tsum nrog koj tus kws kho mob tham txog kev siv triptans.
Thaum twg koj yuav tsum nrhiav kev pab kho mob?
Thaum twg yuav tsum hu rau kws kho mob
Yog tias koj muaj cov kev mob tshwm sim loj heev los ntawm cov tshuaj triptans, yog tias lawv cuam tshuam rau koj cov dej num txhua hnub, lossis yog tias koj xav tias cov tshuaj uas koj tau noj ntev lawm tsis ua haujlwm lawm, tham nrog koj tus kws kho mob. Nws yuav muab tau lwm yam tshuaj triptans lossis lwm yam kev kho mob rau koj.
Cov xwm txheej uas xav tau kev kho mob tam sim ntawd
Cov tshuaj Triptans ua rau muaj cov kev mob tshwm sim loj heev uas tsis tshua muaj (tsawg dua 1%), tab sis yog tias koj muaj cov tsos mob ntawm tus kab mob plawv lossis mob hlwb, koj yuav tsum mus rau chav kho mob ceev (ETU) ntawm tsev kho mob tam sim ntawd .
Cov tsos mob ntsig txog kab mob plawv:
- Mob hauv siab los yog tsis xis nyob
- Lub plawv dhia ceev (Tachycardia) lossis lub plawv dhia qeeb (Bradycardia)
- Ua pa nyuaj (Dyspnea)
Cov tsos mob ntsig txog mob stroke:
Ib qho ntawm cov tsos mob tseem ceeb ntawm tus mob stroke yog ua rau lub cev tsis muaj zog, tsis muaj zog, lossis tsis muaj zog ntawm ib sab ntawm lub cev (hemiplegia). Cov tsos mob no kuj tuaj yeem tshwm sim rau qee qhov mob hnyav ntawm mob taub hau migraine.
Nyob hauv tsev tsis muaj peev xwm txiav txim siab seb qhov tsos mob no yog vim mob taub hau loj lossis mob stroke. Yog li ntawd, yog tias koj xav tias ib sab ntawm koj lub cev tsis muaj zog, mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) tam sim ntawd yam tsis muaj kev ncua . Thaum muaj mob stroke, txhua ob vib nas this uas kev kho mob ncua tuaj yeem ua rau lub hlwb puas tsuaj mus tas li.
Yog tias koj tsis tau muaj mob migraine ua ntej thiab muaj mob taub hau hnyav nrog cov tsos mob zoo li mob stroke zoo li no, xav txog qhov no ua xwm txheej ceev.
Triptan twg zoo tshaj plaws rau kuv?
Nov yog ib lo lus nug uas ntau tus neeg nug. Tsis muaj ib yam dab tsi hu ua "triptan zoo tshaj plaws." Ib yam tshuaj uas ua haujlwm zoo heev rau ib tus neeg yuav tsis ua haujlwm zoo rau lwm tus. Koj tus kws kho mob yuav txiav txim siab seb triptan twg zoo tshaj plaws rau koj thiab yuav noj nws li cas (tshuaj ntsiav lossis tshuaj tsuag) raws li ntau yam, suav nrog qhov xwm txheej ntawm koj qhov mob taub hau, koj lwm yam mob, thiab lwm yam tshuaj uas koj noj .
Ua ntej nrhiav tau cov tshuaj triptans, cov neeg mob taub hau migraine muaj lub neej nyuaj heev. Niaj hnub no, ua tsaug rau cov tshuaj no, ntau lab tus tib neeg tsis muaj mob taub hau migraines thiab tuaj yeem ua neej zoo li qub. Yog tias koj raug mob taub hau migraines, tsis txhob tsuas yog ua siab ntev rau qhov mob xwb. Tham nrog koj tus kws kho mob thiab saib seb cov tshuaj triptans puas tuaj yeem pab koj. Cov tshuaj no tuaj yeem pab koj ua neej nyob ib txwm, es tsis txhob raug mob taub hau migraines.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Triptans yog ib hom tshuaj uas muab los tswj qhov mob thiab cov tsos mob ntawm tus mob migraine thaum nws pib.
- Cov no tsis tiv thaiv tau mob taub hau migraines (tshwj tsis yog mob taub hau migraines thaum muaj hli). Lawv ua haujlwm ua cov tshuaj "cawm".
- Cov tshuaj Triptans ua haujlwm los ntawm kev so cov hlab ntsha hauv lub hlwb, thaiv cov cim qhia mob, thiab tswj cov mob migraines.
- Cov tshuaj no muaj kev nyab xeeb heev, tsis ua rau quav tshuaj, thiab muaj tsawg tsawg qhov kev phiv.
- Cov no tsis haum rau cov neeg uas muaj mob xws li kab mob plawv lossis ntshav siab uas tsis tuaj yeem tswj tau. Qhia rau koj tus kws kho mob txog txhua yam tshuaj uas koj noj.
- Siv cov no tsuas yog raws li qhov ntau thiab tsawg uas koj tus kws kho mob pom zoo. Kev siv ntau dhau tuaj yeem ua rau mob taub hau ntxiv.
- Yog tias koj muaj cov tsos mob hnyav xws li mob hauv siab lossis tsis muaj zog ntawm ib sab ntawm lub cev, mus rau chav kho mob ceev (ETU) tam sim ntawd.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus