Lɛ wi lan ɔltin bɔt di Pituitary Gland: di smɔl "bɔs" na yu bɔdi!

Yu dɔn ɛva tink se wan smɔl gland we de na yu bɔdi, lɛk motoka in injin, de kɔntrol yu wan ol bɔdi? Yu nɔ tink se i wɔndaful? Dɛn kɔl dis smɔl gland we smɔl lɛk pis, we de ɔnda wi bren, we de du bɔku wɔndaful tin dɛn, di pituitary gland . Mek wi tok abaut dis smol ‘bos’ ditail tide, no bi so?

Wetin na di pituitary gland? Usay i de?

Fɔ tɔk am simpul wan, yu pituitary gland na smɔl gland we di sayz lɛk pis, we de na di say we yu bren de, jɔs dɔŋ wan ɔda impɔtant pat we dɛn kɔl di haypothalamus . I de insay wan smɔl rum we dɛn protɛkt na di say we yu bren de. Wi kɔl dis chɛmba di Sella Turcica . Dis na pat pan yu ɛndokrin sistɛm . I de mek sɔm kayn ɔmon dɛn we impɔtant fɔ wi bɔdi, ɛn i de tɛl ɔda ɛndɔkrin gland dɛn fɔ pul dɛn ɔmon dɛn ya. I smɔl, bɔt i de du big wok, nɔto so?

Naw yu go mɔs de wɔnda wetin na gland ɛn wetin na ɔmon.

Gland na ɔgan we de mek wan ɔ mɔ tin dɛn lɛk ɔmon, jus we de mek pɔsin digest, swet, ɛn kray wata. di εndokrin gland dεm de kכl כmon dεm dairekt insay di bכdi.

Ɔmon dɛn tan lɛk kemikal mɛsenja dɛn we de kɔdinɛt di wok we wi bɔdi de du. Dɛn kin travul tru di blɔd ɛn kɛr mɛsej to di ɔgan dɛn, di skin, di mɔsul dɛn, ɛn ɔda tisu dɛn. Dɛn mɛsej ya kin tɛl di bɔdi wetin fɔ du ɛn ustɛm fɔ du am.

yu pituitary gland dεn sheb to tu men pat dεm: di antεriכr pituitary ( fכnt lכb) εn di posita pituitary ( bak lכb). dis gland de kכnekt to di haypothalamus bay wan sכm sכm sכm blכd vεsεl dεm εn nεv dεm we dεn k כl di pituitary st כl כ infundibulum .

Wetin na di impɔtant ɔmon dɛn we di pituitary gland de mek?

Lɛ wi luk naw us impɔtant ɔmon dɛn de kɔmɔt na dis smɔl gland.

di כmon dεm we de kכmכt na di Anterior Lobe

Dis pat de mek ɛn pul bɔku impɔtant ɔmon dɛn na di blɔd.

• Adrenocorticotropic hormone (ACTH) ɔ corticotrophin: Dis kin afɛkt di we aw wi bɔdi kin biev we wi strɛs . i de mek yu adrenal gland dεm fכ mek di "strεs כmon" kכtisol . Kɔtisol gɛt bɔku wok dɛn. Fɔ ɛgzampul, i de kɔntrol di mɛtabolism , i de mek di blɔd prɛshɔn kɔntinyu , i de kɔntrol di glukɔs we de na di blɔd , ɛn i de mek di inflamɛns nɔ bɔku .
• כmon we de mek di fכlikul dεm (FSH): .If yu na man, FSH de mek di sεl dεm prodyuz. If yu na uman, FSH de mek di ovaria dɛn mek ɛstrojen , we de ɛp bak fɔ mek di eg dɛn machɔ. Dɛn kin kɔl am bak gonadotrofik ɔmon .
• Growth hormone (GH): Dis kin ɛp pikin dɛn fɔ gro, we min se dɛn kin gro lɔng. pan big pipul dεm, i de εp fכ mεnten hεlth mכsul εn bon dεm εn kכntrכl di fεt we dεn de kip. GH de afekt yu mεtabolism bak (di we aw yu de kכnvכlt di it we yu de it to enεji).
• Luteinizing hormone (LH): I de mek yu ovuleshɔn if yu gɛt ovaria, ɛn i de mek yu gɛt tɛstostɛron if yu gɛt tɛstikul. LH na gonadotrophic homon bak biכs i de kכntro di wok we di ovaria dεm εn di tεstikul dεm (dεn kכl dεm bak gonads ).
• Prolactin: Dis de mek yu gi pikin milk afta yu bɔn pikin. I kin afɛkt bak di we aw big pipul dɛn kin bɔn pikin ɛn di we aw dɛn kin du mami ɛn dadi biznɛs.
• Tayroyd-stimulating hormone (TSH): TSH de mek yu tayroyd gland mek tayroyd ɔmon, we de ɛp fɔ manej yu mɛtabolism, yu ɛnaji lɛvɛl, ɛn yu nervɔs sistɛm .

di כmon dεm we de kכmכt na di Posita Lob

dis pat nכ de mek כmon dεm, bכt tu כmon dεm we di haypothalamus de mek dεn de stכr dεm ya εn kכmכt na di bכdi we nid de.

• Antidiuretic hormone (ADH) ɔ vasopressin: Dis ɔmon de balans di wata ɛn sodium we de na yu bɔdi.
• כksijεn: na di haypothalamus de mek כksijεn εn di pituitary gland de stכr εn rilis am. i de εp fכ mek i izi fכ bכn bay we i de sεnd signal to di uterus fכ kכntrakt we i de bכn. I de ɛp bak fɔ mek di milk let-dɔwn ɛn mek mama ɛn papa ɛn pikin dɛn gɛt tayt padi biznɛs. כksijεn de ple rol bak fכ mek di sεl dεm de muv.

Wetin na di men wok we di pituitary gland de du?

Sɔntɛm yu dɔn ɔndastand naw aw dis smɔl gland impɔtant. Na sɔm pan di men wok dɛn we i de du:

• Gro
• Mεtabolism (dat na aw yu de kכnvכlt di it we yu de it to enεji εn mεnεj da enεji de) .
• Fɔ mek dɛn bɔn pikin dɛn
• Fɔ ansa strɛs ɔr bɔdi prɔblɛm
• Laktashɔn
• Wata ɛn sɔdiɔm (sɔl) balans
• Fɔ bɔn pikin ɛn fɔ bɔn pikin

Imajin di tɛmostayt we de na yu os.I tan lɛk wan. Di tɛmostayt de wach di tɛmpracha na yu os ɔltɛm ɛn i de wok fɔ mek yu fil fayn, nɔto so? I de sɛn signal to di hita ɛn kul fɔ mek di tɛmpracha go ɔp ɔ dɔŋ dis kayn we, fɔ mek di tɛmpracha na yu os kɔntinyu fɔ de na wan patikyula lɛvul.

Yu pituitary gland jɔs tan lɛk yu, de wach aw yu bɔdi de du tin. Di pituitary gland de sɛn mɛsej to yu ɔgan ɛn gland dɛn tru in ɔmon dɛn, ɛn se, ‘Na dis yu nid fɔ du, dis tɛm.’ Us sɛtin dɛn we fayn fɔ yu bɔdi kin dipen pan bɔku tin dɛn lɛk yu ej ɛn yu man ɔ uman.

Wetin na di rilayshɔn bitwin di haypothalamus ɛn di pituitary gland?

yu pituitary gland ɛn haypothalamus de wok togɛda fɔ mek di Hypothalamus-Pituitary complex . Dis tan lɛk di men kɔntrol sɛnta na yu bren, we de kɔntrol di impɔtant wok dɛn we yu bɔdi de du.

di haypothalamus na di pat pan yu bren we de du sכm pan di bεsi wok dεm we di bכdi de du. I de sɛn mɛsej to yu ɔtonomik nɛvɔ sistɛm , we de kɔntrol tin dɛn lɛk blɔd prɛshɔn, at rit, ɛn aw yu de blo. I de tɛl di pituitary gland bak fɔ mek ɛn pul ɔmon dɛn we de afɛkt ɔda pat dɛn na di bɔdi.

as wi bin dכn tכk, di pituitary gland de kכnekt to di haypothalamus bay di pituitary stalk . na tru dis stכl di haypothalamus de kכmכnik wit di antεriכr pituitary gland tru כmon dεm εn wit di posita pituitary gland tru di nεv impuls dεm. di haypothalamus de mek כksijεn εn antidiuretic כmon dεm bak. di haypothalamus de rispansabl fכ stכr εn rilis dεn כmon dεm ya to di posita pituitary gland.

di haypothalamus de kכmכnik wit εn stimulate di pituitary gland, we de mek כmon dεm lεk:

• Ɔmon we de pul kɔtikotrofin (CRH) .
• Dopamin we dɛn kɔl Dopamin
• Ɔmon we de rilis gonadotropin (GnRH) .
• Ɔmon we de pul di ɔmon we de mek pɔsin gro (GHRH) .
• Somatostatin we dɛn kɔl Somatostatin
• Ɔmon we de pul tayrotropin (TRH) .

Bikɔs dɛn tu ya (haypothalamus ɛn pituitary) de wok so klos togɛda, if wan pan dɛn pwɛl, i kin afɛkt di ɔda wan in ɔmon dɛn bak.

I pɔsibul fɔ liv we yu nɔ gɛt di pituitary gland?

Yɛs, yu kin liv we yu nɔ gɛt yu pituitary gland, bɔt fɔ du dat, yu go gɛt fɔ tek mɛrɛsin we dɛn kɔl riplesmɛnt tɛrapi fɔ tek di pituitary ɔmon dɛn we nɔ de. Bikɔs di ɔmon dɛn we de na di pituitary rili impɔtant fɔ mek di bɔdi kɔntinyu fɔ du difrɛn wok dɛn na di bɔdi. If ɔl di ɔmon dɛn we de na di pituitary nɔ de igen ɛn dɛn nɔ trit am, i kin mek pɔsin in layf de pan denja.

Wetin na di sik dɛm wae kin afɛkt di pituitary gland?

difrεn mεdikal kכndyushכn dεm de we de afekt כ kכz fכ di wok we di pituitary gland de du. Wi kin sheb dɛn tin ya to 4 men grup dɛn:

• Di adenoma dɛn we de na di pituitary
• Di sik we dɛn kɔl hypopituitarism
• Di sik we dɛn kɔl Hyperpituitarism
• Ɛmpti sella sindrom

Lɛ wi tɔk bɔt ɛni wan pan dɛn tin ya smɔl mɔ.

Di Adenoma dɛn we de na di Pituitary

dis na wan kayn benign tumor we de divεlכp na di pituitary gland. di pituitary adenomas de mek lεk 10% to 15% pan כl di tכmכro dεm we de divεlכp insay di bren.

Bɔku tɛm, dɛn tin ya kin gro fayn fayn wan. Bɔt if dɛn big pasmak, dɛn kin mek yu gɛt sayn dɛn bay we dɛn prɛs pan tin dɛn we de nia de. sכmtεm dεn kin prεs pan di optik nεv, we kin mek i gεt prכblεm fכ si (lεk fכ lכs di pεrifεral vishכn). Na smɔl tɛm nɔmɔ, big pituitary adenomas kin blɔd.

Sɔm pituitary adenomas de mek tumɔs pituitary ɔmon. dεn kכl dεn tin ya ``Functioning/Secreting`` adenomas . Sɔm nɔ kin mek ɛni ɔmon. dεn kכl dεn tin ya ``Nכn-fכnshכn`` adenomas .

difrεn kayn adenoma dεm de we de wok, i dipכnt pan di כmon we dεn de mek. di adenoma we de wok pas ɔl na di prolaktinoma . Dis kin mek dɛn mek bɔku bɔku prɔlaktin. Dɛn kin trit prolaktinoma wit mɛrɛsin.

Pituitary tumors we rili big ɛn/ɔ we de mek ɔmon nid fɔ gɛt tritmɛnt, bɔku tɛm dɛn kin du ɔpreshɔn .

Di sik we dɛn kɔl hypopituitarism

Dis na wan sik we yu pituitary gland de mek tumɔs smɔl pan wan, sɔm, ɔ ɔl di ɔmon dɛn we i de mek.

Bɔku tɛm, dɛn kin si wan ɔmon we nɔ de. If yu nɔ gɛt tu ɔ mɔ pituitary ɔmon dɛn, dɛn kin kɔl am panhypopituitarism . Dis kin apin afta dɛn dɔn ɔpreshɔn di pituitary ɔ afta dɛn dɔn gi di bren raytin .

di men tin we kin mek yu gɛt haypopituitarism na we di pituitary gland ɔ di haypothalamus kin pwɛl.

Bɔku patikyula sik dɛn de we gɛt fɔ du wit dis sik:

• di hכmon we de gro: Dis kin apin we di pituitary gland nכ de prodyuz inof gכt כmon (GH). pan pikin dεm, dεn nכ de gro εn divεlכpmεnt, εn dεn kin delay fכ bכn. pan big pipul dεm, mεtabolik prכblεm kin apin.
• Sɛntral dayabitis insipidus:dis kin apin we di pituitary gland nכ de prodyuz inof antidiuretic hormone (ADH). Dis kin mek di bɔdi pul bɔku urine ɛn i nɔ kin ebul fɔ kip wata.
• sεntri haypogonadism: dis kin apin we di pituitary gland nכ de prodyuz inof luteinizing hormone (LH) εn fכlikul-stimulating hormone (FSH). Dis kin mek prɔblɛm wit di we aw pɔsin de du mami ɛn dadi biznɛs, di divɛlɔpmɛnt, ɛn di we aw i kin bɔn pikin.
• sεntri adrenal insufisεns: dis kin apin we di pituitary gland nכ de prodyuz inof ACTH. Dis kin mek di bɔdi nɔ ebul fɔ mek kɔtisol.
• Sεntri haypotayroydism: Dis kin apin we di pituitary gland nכ de prodyuz inof thyroid-stimulating hormone (TSH), we de mek di tayroyd כmon lεvεl dכn lכw.

Dɛn kin trit di haypopituitarism bay we dɛn de gi di ɔmon dɛn we nɔ de na do ɛn wach dɛn lɛvɛl dɛn de tru blɔd tɛst.

Di sik we dɛn kɔl Hyperpituitarism

Dis na wan sik we yu pituitary gland de mek tumɔs wan ɔ mɔ ɔmon. dis kin kכz bak fכ wan fכnshכn pituitary adenoma (wan tכmכro we nכ de kεnsar).

Bɔku patikyula sik dɛn de we gɛt fɔ du wit dis sik:

• Acromegaly: Dis kin apin we di pituitary gland de mek tumɔs growth ɔmon (GH) we i big. dis kin mek sכm pat dεm na di bכdi big, lεk di an, fut, εn/כ insay כgan dεm, εn mεtabolik prכblεm.
• Gigantism: Dis kin apin we di pituitary gland de mek tumɔs growth ɔmon (GH) we i smɔl ɔ we i yɔŋ. Dis kin mek i gro kwik kwik wan ɛn i kin ayt pasmak.
• Cushing in sik: Dis kin apin we di pituitary gland de mek tumɔs ACTH (we de mek di adrenal gland prodyuz tumɔs kɔtisol). Dis kin mek yu gɛt bɔku bɔku wet wantɛm wantɛm na sɔm say dɛn na yu bɔdi, yu blɔd shuga kin bɔku, ɛn i kin ivin mek yu gɛt tayp 2 dayabitis .
• Hyperprolactinemia: Dis kin apin we di pituitary gland de mek tumɔs prolactin. dis kin mek di fεtiliti dכn εn di milk we de kכmכt frכm di nipl dεm (galactorrhea) .

Ɛmpti Sɛlla Sindrɔm

Empty Sella Syndrome (ESS) na wan sik wae nɔr kin bɔrku. i kin apin we di pituitary gland flat כ shrunk bikoz fכ wan prכblεm wit di bon strכkchכ we de rawnd am εn protεkt am, we dεn kכl di Sella Turcica . Di Sella Turcica na wan chɛmba we tan lɛk sadul. I kɔmɔt frɔm di Latin wɔd fɔ "Turkish seat."

Ɛmpti sɛl na raydiografik diagnosis.Bɔrku tɛm, dis nɔr kin bi rial mɛdikal kɔndishɔn, ɛn dɛn kin no am bay chans we dɛn de skan am.

Sɔm tɛm, ESS kin mek yu gɛt sɔm sayn dɛm lɛk wae yu nɔr de balans yu ɔmon, yu ed kin at ɔltɛm, ɛn yu kin chenj yu yay. Bɔt if di ɔmon we de na di pituitary de insay di nɔmal rɛnj, i nɔto natin fɔ wɔri bɔt.

Us sayn dɛn kin apin if prɔblɛm de wit di pituitary gland?

big big pituitary adenomas (dεn na tכmכro dεm we nכ de kεnsar) kin push כ damej di tisu dεm we de nia. Dis kin mek yu gɛt sɔm kayn sik lɛk:

• Prɔblɛm dɛn we yu de si (lɛk we yu nɔ de si di say we yu de si) .
• Ed de at
• di hכmon imbalans we de kכz we di hכmon dεm na di pituitary de inkrεs כ dכn

Di ɔmon we de na di pituitary nɔ balans kin mek yu gɛt difrɛn sayn dɛn, i kin dipen pan di ɔmon we i afɛkt. Sɔm ɛgzampul dɛn na:

• Pikin dɛn kin gro sloslo ɔ gro pasmak
• di fεtiliti we uman εn man dεn dכn dכn (Infertility) .
• Menstrual saykl dɛn we nɔ de ɔltɛm
• We yu de gɛt mɔ wet ɔ yu de lɔs fɔ natin
• Pwɛl hat ɛn/ɔ Wɔri wɔri

If yu gɛt ɛni nyu sik we nɔ de dɔn, i rili impɔtant fɔ tɔk to yu dɔktɔ. Dɛn kin du tin lɛk simpul blɔd tɛst fɔ no if yu sik na bikɔs ɔf ɔmon ɔ ɔda tin.

Udat wi fɔ tɛl bɔt prɔblɛm lɛk dis?

Di prɔblɛm dɛn we de na di pituitary gland na di wan dɛn we de stɔdi bɔt di bɔdi kin trit am .

Endocrinologist na dɔktɔ we spɛshal pan sik dɛn we gɛt fɔ du wit ɔmon. I kin no di sik dɛn we de na di ɛndokrin (ɔmon), mek plan fɔ trit am ɛn aw fɔ mɛn am, ɛn gi am mɛrɛsin.

If yu gɛt prɔblɛm wit di pituitary gland, lɛk pituitary adenoma, we de afɛkt di strɔkchɔ dɛn na yu bren ɛn/ɔ yu nid fɔ du ɔpreshɔn, yu go nid fɔ go to nyurosɔjɔn .

Aw dɔktɔ dɛn kin no if pɔsin gɛt prɔblɛm wit di pituitary gland?

Bikɔs yu pituitary gland de pul ɔmon dɛn dairekt insay yu blɔd, bɔku tɛm dɔktɔ dɛn kin mɛzhɔ di pituitary ɔmon lɛvɛl bay we dɛn de du blɔd tɛst .

If yu ɔmon nɔ de ɔltɛm, yu dɔktɔ kin ɔda bak fɔ mek dɛn du imej tɛst, lɛk CT skan ɔ MRI skan, fɔ si if prɔblɛm de wit di pituitary gland. כltu, dεn kin du spεshal pituitary MRI fכ si klia wan di pituitary gland εn in stכl.

Aw wi kin mek wi pituitary gland gɛt wɛlbɔdi?

Di bɛst we fɔ mek yu pituitary gland gɛt wɛlbɔdi na fɔ protɛkt yu ed. Injuri na ed ɛn traumatik bren injuri (TBI) .I kin pwɛl yu pituitary gland, ɛn mek i mek bɔku ɔ tu smɔl ɔmon dɛn.

Na sɔm tin dɛn we yu kin du fɔ mek yu nɔ gɛt ɛni bad bad tin na yu ed ɛn yu bren:

• Wear sit bɛlt ɛnitɛm we yu de insay motoka.
• Drayv sef wan.
• Wear ɛlmɛt we yu de rayd baysikul, motoka, ɔ ple spɔt we gɛt fɔ du wit kɔntakt.
• Tek step fɔ mek yu nɔ fɔdɔm, mɔ if yu de pan big risk fɔ fɔdɔm. Dis kin min fɔ du ɛksɛsayz we de mek yu gɛt mɔ trɛnk ɛn balans, fɔ pul tin dɛn we de ambɔg yu ɛn tin dɛn we de slipul na yu os, fɔ yuz sɔntin we de ɛp yu fɔ waka, ɛn fɔ chɛk aw yu de si.
• If yu gɛt smɔl pikin dɛn, mek di say dɛn we dɛn de liv ɛn ple sef.

Ustɛm yu fɔ go to dɔktɔ bɔt di pituitary gland?

If yu gɛt sayn dɛm fɔ pituitary adenoma ɛn/ɔ simptom dɛm fɔ wan ɔmon imbalans, i rili impɔtant fɔ tɔk to yu dɔktɔ. Dɛn kin du sɔm tɛst fɔ si if ɛnitin de we nɔ fayn wit yu pituitary gland.

If yu jɔs dɔn gɛt siriɔs injuri na yu bren (Traumatic Brain Injury - TBI) , i go mɔs bi se yu dɔktɔ go wach aw yu pituitary gland de wok fɔ si if i de wok fayn ɛn if di injuri dɔn pwɛl am.

Fɔ sɔmtin, na di tin dɛn we wi nid fɔ mɛmba (Take-Home Message):

Yu pituitary gland na rili smɔl, bɔt pawaful gland we de kɔntrol bɔku impɔtant tin dɛn we de apin na yu wan ol bɔdi! I tan lɛk smɔl ‘bɔs’.

I de mek ɔmon dɛn we de kɔntrol bɔku tin dɛn, lɛk aw yu de gro, aw yu de it, aw yu de bɔn pikin, ɛn aw yu de dil wit strɛs. So, fɔ kip dis smɔl gland wɛl rili impɔtant.

• Tek kia ɔf yu ed: wɛr ɛlmɛt, de sef.
• Yu fɔ no bɔt di sayn dɛn we nɔ kɔmɔn: Tɛl dɔktɔ if yu gɛt ed we de at ɔltɛm, yu nɔ de si fayn, yu de chenj yu wet wantɛm wantɛm, ɔ yu taya pasmak.
• Nɔ wɔri: bɔku pan di prɔblɛm dɛn we de wit di pituitary gland gɛt gud tritmɛnt. If dɛn no dɛn kwik kwik wan, dɛn kin ebul fɔ manej dɛn fayn fayn wan.

Yu dɔn no bɔku tin naw bɔt dis wɔndaful smɔl pat na yu bɔdi. If yu gɛt ɛni kwɛstyɔn ɔ tin we de mɔna yu, nɔ ɛva shem fɔ tɔk to dɔktɔ. Stay wit wɛlbɔdi!

` Pituitary gland, כmon dεm, bren, εndokrin sistεm, pituitary sik dεm, haypothalamus, growth כmon