Lɛ wi lan mɔ bɔt Leptin, we sikrit wan de ɛp yu fɔ kɔntrol yu wet.

Wi ɔl kin wɔri bɔt wi wet sɔntɛnde, nɔto so? Sɔm pipul dɛn kin want fɔ lɛf fɔ it bɔku bɔku it dɛn, ɛn ɔda wan dɛn kin want fɔ kɔntinyu fɔ gɛt wɛlbɔdi. Yu dɔn ɛva tink se smɔl tin de insay wi bɔdi we de ɛp wi fɔ kɔntrol wi wet? Leptin na wan pan dɛn sikrit kɔntrol dɛn de. Tide, lɛ wi tɔk bɔt lɛptin insay wan simpul we we yu go ɔndastand.

Wetin na Lɛptin?

Fɔ tɔk am simpul wan, lɛptin na ɔmon we yu bɔdi in fat sɛl dɛn, ɔ adipɔz tisu de mek . I tan lɛk smɔl signal sistɛm we de ɛp yu fɔ kɔntrol yu wet fɔ lɔng tɛm. Aw i kin du dat? Leptin de kɔntrol yu angri ɛn i de ɛp yu bak fɔ fil ful, ɔ fɔ satisfay .

Tink bɔt am dis we: lɛptin tan lɛk mɛsenja we de tɛl yu bren ɔmɔs fat yu gɛt na yu bɔdi. Sayɛnsman dɛn jɔs dɔn fɛn lɛptin jɔs lɛk 1994. So bɔku risach stil de go bifo, fɔ ɔndastand di rayt we aw i de wok. Dɛn dɔn ɔlrɛdi no bɔt lɛptin fɔ di wok we i de du fɔ mek pɔsin gɛt wet, Alzaima sik , fɔ mek uman bɔn pikin, ɛn fɔ mek i nɔ ebul fɔ bɔn pikin .

We yu yɛri se lɛptin de kɔntrol di wet, yu kin tink se, "O... so a tink se a fɔ fɛn we fɔ kɔntrol lɛptin." Bɔt fɔ tɔk tru, fɔ chenj dis ɔmon nɔ izi lɛk aw yu tink.

Wetin kin rili apin wit lɛptin?

Di men wok we lɛptin de du na fɔ ɛp yu fɔ kɔntinyu fɔ gɛt yu bɔdi wet. Dat min se i de ɛp fɔ mek yu gɛt balans fɔ lɔng tɛm bitwin di it we yu de it ɛn di pawa we yu bɔdi de yuz. Leptin de mek yu nɔ fil angri ɔltɛm. I de kɔntrol bak di angri signal dɛm we kin kam we di bɔdi nɔ nid ɛnaji, ɔ kalori .

Lɛptin de wok mɔ bay we i de afɛkt wan pat na yu bren we dɛn kɔl di haypothalamus . di haypothalamus na di ki sεnta fכ kכntrכl angri εn yus fכ εnεji. כltu, lεptin rεsεpכta dεm de na כda pat dεm na di bכdi bak.

Di impɔtant tin na dat lɛptin nɔ jɔs de kɔntrol yu angri lɛvɛl frɔm wan it to di ɔda wan. Bifo dat, i kin ɛp fɔ chenj di we aw yu de it fɔ lɔng tɛm, kɔntrol di we aw yu de spɛn bɔku ɛnaji, ɛn ɛp yu fɔ kɔntinyu fɔ gɛt yu wet.

We yu de tray fɔ lɔs yu wet, di lɛptin lɛvɛl de go ɔp. Aw dat kin wok? As yu bɔdi de lɔs fat, di lɛptin lɛvɛl de go dɔŋ. Dis kin sɛn signal to yu bɔdi, se, "O, a nɔ de it bɛtɛ, a angri." Dis kin mek yu fil bad bad wan ɛn yu kin want fɔ du sɔntin. Dis kin mek yu it mɔ pas aw yu fɔ it. Na dat mek sɔntɛnde i kin at fɔ mek yu kɔntinyu fɔ lɔs yu wet.

Sayɛnsman dɛn stil de stɔdi bɔt lɛptin. Dɛn biliv se i kin afɛkt bak:

• Yu mɛtabolism
• di εndokrin sistεm, dat na di כmon sistεm
• Imyun sistɛm

Aw dɛn kin kɔntrol di lɛptin lɛvɛl?

di wayt adipos tisu na yu bɔdi, ɔ wayt fat sɛl dɛn de mek ɛn kɔmɔt na yu bɔdi. Dɛn wayt fat sɛl ya na di men kayn fat we de na wi bɔdi.

Bikɔs lɛptin kɔmɔt frɔm fat sɛl dɛn, di lɛptin we de na yu blɔd gɛt sɔntin fɔ du wit di fat we de na yu bɔdi. Fɔ tɔk am simpul wan, if yu nɔ gɛt bɔku fat na yu bɔdi, yu nɔ gɛt bɔku lɛptin. If yu gɛt mɔ bɔdi fat, yu gɛt mɔ lɛptin.

If yu bɔdi fat mas de go ɔp as tɛm de go, di lɛptin lɛvɛl de go ɔp. di kכnvεshכn, if yu bכdi fεt mas dכn, di lεptin lεvεl de dכn.

Wetin kin apin if di lɛptin lɛvɛl go ɔp?

Pɔsin we fat kin gɛt bɔku bɔku lɛptin na in bɔdi. Dɛn kɔl dis hyperleptinemia . we lεptin de inkrεs dis we, wan kכndyushכn kin apin we di bכdi nכ de rεspכnd to lεptin. Dɛn kɔl dis lɛptin rɛsistɛns .

Ɔda tin dɛm wae kin gɛt fɔ du wit hyperleptinemia na:

• Pwɛl at
• Fɔ it adikshɔn
• Nyurodijɛnɛraytiv dizayd dɛn
• Fat liva sik we nɔ de drink rɔm ( NAFLD ) .
• Rabson-Mendenhall sindrom we gɛt di sik

Wetin na Leptin Resistance?

If yu gɛt lɛptin rɛsistɛns, yu bren nɔ de ansa lɛptin nɔmal wan. ivin if lεptin de kכntinyu fכ sεnd signal to yu bren, yu nכ de gεt di "ful" filin. Dis kin mek yu kɔntinyu fɔ it, pan ɔl we yu gɛt bɔku fat na yu bɔdi.

Bikɔs ɔf dis we i tan lɛk se yu nɔ gɛt lɛptin, yu bɔdi kin tink se yu "de angri." Fɔ mek yu nɔ gɛt trɛnk, yu bren de mek yu ɛnaji go dɔŋ ɛn i de ridyus di kalori dɛn we yu de bɔn we yu de rɛst. dis min se yu Basal Mεtabolik Rεt (BMR) de dכn.

So, di leptin resistance de mek yu fil angri ɔltɛm, ɛn yu BMR de go dɔŋ bak. Dis kin mek di wet we pɔsin kin gɛt mɔ ɛn mɔ.

Naw, sayɛnsman dɛn de tray fɔ mek mɛrɛsin dɛn we go ebul fɔ mɛn di wan dɛn we nɔ gɛt lɛptin.

Simptom dɛm fɔ lɛptin rɛsistɛns

Di men sayn dɛm we de sho se pɔsin nɔ ebul fɔ tek lɛptin na we i de angri ɔltɛm, ɔ we i de it pasmak , ɛn we i de it mɔ it. Dɛn sayn ya kin apin we yu gɛt bɔku bɔku fat na yu bɔdi, sɔntɛm yu kin ivin gɛt bɔku bɔku fat.

Bɔt dɛn kayn sik ya kin bi bikɔs ɔf bɔku ɔda tin dɛn, nɔto jɔs di lɛptin we nɔ de wok. As sayɛnsman dɛn stil de lan bɔt lɛptin, i pɔsibul se dɛn go fɛn mɔ sayn dɛn we de sho se pɔsin nɔ ebul fɔ fɛt lɛptin tumara bambay.

Wetin kin apin if yu gɛt Leptin Deficiency?

We pɔsin nɔ gɛt lɛptin, we dɛn kin kɔl bak haypoleptinemia, na wan tin we nɔ kin apin so ɔltɛm. di men kכndyushכn we de asai wit dis na we dεn bכn wit lεptin dεfisit . Dis na wan jenɛtik kɔndishɔn we dɛn bɔn yu wit. Dis min se yu adipos tisu nɔ ebul fɔ mek lɛptin.

We lɛptin dɔn lɔs, yu bɔdi kin tink se fat nɔ de na di bɔdi. Dis kin mek pipul dɛn nɔ ebul fɔ kɔntrol dɛn angri ɛn want fɔ du sɔntin. fכ dis rizin, yכng pikin dεm we dεn bכn wit lεptin dεfisit de gεt klas III fכ fat εn dεn delay fכ bכn.

Dis sik kin gɛt fɔ du wit sɔm ɔda sik dɛn bak:

• Dislipidemia (na di fat we nɔ balans, lɛk kɔlɔstrel ɛn triglisɛrɛyd) .
• Fat liva sik
• Baktri infekshɔn dɛn we kin kam bɔku tɛm
• Hyperinsulinemia (we dɛn de mek insulin pasmak) .
• haypogonadotropik haypogonadism (di lכw sεks כmon lεvεl) .

Aw fɔ chɛk di lɛptin lɛvɛl?

Wan blɔd tɛst kin chɛk yu lɛptin lɛvɛl. Bɔt, dɔktɔ dɛn nɔ kin chɛk ɔlman in lɛptin lɛvɛl. Dɛn kin jɔs tink bɔt fɔ du lɛptin tɛst pan dɛn tin ya:

• If yu smɔl pikin gɛt gred 3 fat
• If yu fat ɛn yu de fil angri ɔltɛm

Wetin na di nɔmal lɛptin lɛvɛl?

Tipikli, di lεptin lεvεl kin kכmכt frכm:

• Fɔ uman dɛn: 0.5 to 15.2 nanogram pan wan mililita ( 0.5 to 15.2 ng/mL ) .
• Fɔ man dɛn: 0.5 to 12.5 nanogram pan wan mililita ( 0.5 to 12.5 ng/mL ) .

כltu, dεn nכmal valyu dεm ya kin difrεn sכmtεm frכm lab to lab. So, mek shɔ se yu chɛk di nɔmal rɛnj na yu tɛst ripɔt, ɔ aks yu dɔktɔ if yu gɛt ɛni kwɛstyɔn bɔt yu rizɔlt.

Aw a go mek mi lɛptin lɛvɛl go ɔp?

Infakt, nɔto bɔku tin yu kin du fɔ mek yu lɛptin lɛvɛl go ɔp fɔ mek yu nɔ angri ɔ nɔ want fɔ it. dat na biכs di lεptin lεvεl dεm we yu gεt de riliyt to di כmכnt כf adipos tisu we yu gεt na yu bכdi.

Wan stɔdi dɔn sho se pipul dɛn we nɔ de slip fayn kin gɛt bɔku ghrelin (di ɔmon we de mek pɔsin angri) ɛn dɛn kin gɛt lɛptin we nɔ kin bɔku. So, if yu slip fayn, dat kin ɛp fɔ mek yu ɔmon dɛn balans.

Sayɛnsman dɛn dɔn tɔk se lɛptin ɛn triglisɛrɛyd dɛn gɛt sɔntin fɔ du wit dɛnsɛf(Dis na wan kayn fεt bak we dεn kכl lipid). Sɔm stɔdi dɛn dɔn sho se we di triglisɛrɛyd lɛvɛl bɔku, i kin afɛkt di we aw lɛptin de wok. Bɔt difrɛn we dɛn de we pipul dɛn kin tink bɔt dɛn stɔdi dɛn ya. Sɔm sayɛnsman dɛn tink se it we dɛn mek fɔ mek di triglisayz nɔ bɔku, dat kin ɛp fɔ mek di lɛptin bɔku, bɔt ɔda wan dɛn nɔ gri wit dat.

Us it dɛn we gɛt bɔku lɛptin?

Lɛptin na ɔmon we yu bɔdi de mek, nɔto tin we de mek yu bɔdi fayn lɛk vaytamɛn C ɔ prɔtin. So, no it nɔ gɛt lɛptin.

Bikɔs lɛptin na nyu tin we dɛn dɔn fɛn, sayɛnsman dɛn stil de lan mɔ bɔt am, mɔ aw i kin afɛkt pɔsin we fat ɛn we i de lɔs in wet. we yu bכdi fεt sכm, i kin at fכ lכs weit biכs di rol we lεptin de du fכ aktibכt di bכdi in "angri" signal.

Mɛsej we dɛn kin kɛr go na os

Okay, so frɔm wetin wi dɔn tɔk bɔt leptin, yu kin mɛmba dis:

• Lɛptin na ɔmon we yu fat sɛl dɛn de mek .
• Di men tin bɔt dis na dat i de ɛp yu fɔ kɔntrol yu wet insay di lɔng tɛm ɛn gi yu di filin fɔ "ful" .
• We yu bɔdi fat de go ɔp, di lɛptin lɛvɛl de go ɔp , ɛn we yu bɔdi fat go dɔŋ, di lɛptin lɛvɛl de go dɔŋ.
• lεptin rεsistεns na we di bכdi gεt lεptin bכt di bren nכ de rεspכnd to am fayn. Dis kin mek yu gɛt mɔ wet.
• Di we aw pɔsin nɔ gɛt lɛptin nɔ kin apin so ɔltɛm .
• Nɔ it nɔ gɛt lɛptin, bikɔs i de mek insay di bɔdi.
• Fɔ liv fayn layf, mɔ fɔ slip fayn , kin ɛp fɔ balans di ɔmon dɛn.

If yu de wɔri bɔt yu wet ɔ yu nid advays bɔt aw fɔ lɔs yu wet fayn fayn wan, tɔk to yu dɔktɔ. Yu kin go bak to dɔktɔ we spɛshal pan ɔmon, we na ɛndokrinɔlɔjis, fɔ tɔk bɔt di program dɛn we dɛn kin du fɔ mek yu nɔ gɛt bɔku bɔku bɔdi. Di tin we impɔtant pas ɔl na fɔ tek kia ɔf yu wɛlbɔdi fɔs.

` Lɛptin, weit kɔntrol, ɔmon, fat, lɛptin rɛsistɛns, angri, satiety