Lɛ wi lan mɔ bɔt insulin. Wetin mek i rili impɔtant fɔ wi bɔdi?

Yu go mɔs dɔn yɛri di wɔd insulin, nɔto so? Sɔntɛm if pɔsin na yu famili gɛt dayabitis, ɔ if yusɛf gɛt dayabitis, yu sabi dis nem bad bad wan. So, wetin na insulin? Wetin mek i rili impɔtant fɔ wi bɔdi? Lɛ wi tɔk bɔt am simpul wan, di we we yu go ɔndastand.

Wetin na insulin? Wetin i de du?

Fɔ tɔk am simpul wan, insulin na ɔmon we dɛn kin mek na wi bɔdi bay wilful. Na wan ɔgan we dɛn kɔl wi pankrias de mek am. Di men wok we insulin de du na fɔ ɛp wi bɔdi in sɛl dɛn fɔ yuz di shuga, ɔ glukɔs we wi de tɔk bɔt mɛrɛsin, frɔm di it we wi de it as ɛnaji.

Tink bɔt am dis we, di sɛl dɛn na wi bɔdi tan lɛk smɔl os dɛn. Dɛn os dɛn ya nid trɛnk fɔ wok. Da ɛnaji de kɔmɔt frɔm glukɔs. Bɔt fɔ mek dis glukɔs go insay di os dɛn we dɛn kɔl sɛl, i nid ki fɔ opin di domɔt. Dat ki na insulin. We insulin opin di domɔt dɛn na di sɛl dɛn, di glukɔs we de na di blɔd de go insay di sɛl dɛn ɛn i kin chenj to ɛnaji.

Naw yu ɔndastand di impɔtant tin we insulin impɔtant, nɔto so? If fɔ sɔm rizin wi pankrias nɔ de mek insulin fayn, ɔ if di bɔdi nɔ ebul fɔ yuz di insulin we i de mek fayn fayn wan, da glukɔs de nɔ go ebul fɔ go insay di sɛl dɛn. Dɔn wetin kin apin na dat di glukɔs lɛvɛl na di blɔd kin jɔs go ɔp. Dis na wetin wi kɔl ay blɔd shuga (haypa glycemia) . If dis kayn tin kɔntinyu, wi go gɛt wan sik we dɛn kɔl dayabitis.

Sɔm kayn insulin de bak we dɛn kin gi na do as tritmɛnt fɔ pipul dɛn we gɛt dayabitis. Wi go tɔk bɔt dat leta.

Yu tink se insulin de mek di shuga we de na di blɔd go dɔŋ ɔ i de mek i go ɔp?

Yɛs, insulin de mek yu blɔd shuga go dɔŋ. Na dat na in men wok. Bɔt wi bɔdi de wok di kayn we we rili strenj. Wan ɔda ɔmon de we de ɛp fɔ mek di blɔd shuga balans, ɛn dat na glukagon. Pan ɔl we insulin de mek di blɔd shuga go dɔŋ, glukagon de mek di blɔd shuga go ɔp we dɛn nid am. Dɛn tu ɔmon ya de wok togɛda fɔ mek wi blɔd shuga kɔntinyu fɔ gɛt wɛlbɔdi.

Bɔt we yu tek insulin na do as tritmɛnt fɔ dayabitis, sɔntɛnde if yu tek mɔ pas di wan we yu nid, yu blɔd shuga kin go dɔŋ tumɔs. Dɛn kɔl dis haypoglycemia . If dis apin, yu nid fɔ it ɔ drink sɔm shuga kwik kwik wan fɔ kɔrɛkt am. Glucagon injɛkshɔn dɛn de bak we dɛn kin gi if yu blɔd shuga dɔn drɔp bad bad wan. I bɛtɛ fɔ mek yu tɔk to yu dɔktɔ bɔt dis.

Usay dɛn kin mek insulin?

As wi bin dɔn tɔk, dɛn kin mek insulin na wi pankrias. mכr prεsis, bay beta sεl dεm we de insay spεshal kכlכsta sεl dεm we dεn kכ l di aylet dεm fכ Langerhans insay di pankrias.Dis ɔmon insulin na di pankrias de mek am. dis na wan εndokrin prכsεs. Dat min se di insulin we dɛn de mek de kɔmɔt dairekt insay di blɔd.

di pankrias gεt כda wok bak, we na εksokrin , we na di rilis fכ εnzym dεm tru dakt dεm we de εp fכ daygεst it.

Us mɛrɛsin dɛn kin gɛt fɔ du wit insulin?

Ilɛksɛf insulin kin go dɔŋ, i kin bɔku, ɔ i nɔ kin wok fayn na di bɔdi, difrɛn kayn mɛrɛsin kin apin.

Dayabitis kɔndishɔn wae kin apun wae insulin nɔr de

If insulin nɔ de wok fayn, di shuga na di blɔd kin go ɔp, ɛn dis kin mek pɔsin gɛt dayabitis. Sɔm kayn dayabitis kin kam bikɔs di pankrias dɔn pwɛl:

• Tayp 1 dayabitis: Dis na wan sik we pɔsin kin gɛt we i de fɛt insɛf . Fɔ tɔk am simpul wan, wi yon imyun sistɛm de atak di beta sɛl dɛn we de mek insulin. As tɛm de go, i kin lɛf smɔl fɔ lɛ di insulin we di bɔdi de mek na di bɔdi nɔ de igen igen.
• Tayp 3c dayabitis (dεn kin kכl am bak pankrias dayabεtis): Dis kin apin we di pankrias dεn dכn pwεl εn i nכ de mek insulin igen. Dis kכndyushכn kin kכz fכ kכndyushכn dεm lεk krεse pankrεas εn sistik fibrosis . I kin apin bak afta dɛn dɔn ɔpreshɔn di pankrias (pancreatectomy).
• Latent autoimmune diabetes in adults (LADA): Dis kin kam bak bay wan awtoimyun riakshɔn, lɛk tayp 1 dayabitis. Bɔt, i kin divɛlɔp sloslo. Dɛn kin no bɔt LADA pan pipul dɛn we dɔn pas 30 ia.

Kɔndishɔn dɛn we kin mek pɔsin nɔ gɛt insulin

Dis na wan men tin bak we kin mek pɔsin gɛt dayabitis. Insulin resistance na we wi mכsul, fεt, εn liva sεl dεm nכ de rεspכnd fayn to insulin. I tan lɛk se di ki we de na di domɔt lɔk nɔ de wok. Dis kin mek yu gɛt tin dɛn lɛk:

• Prediabetes: Dis na wan sik wae de blɔd shuga lɛvɛl pas aw i fɔ gɛt, bɔt nɔr de ay fɔ kɔl am tayp 2 dayabitis. Insulin resistance na di men tin we kin mek i gɛt dis sik.
• Tayp 2 dayabitis: Dis sik kin apin we insulin rɛsistɛns de go ɔp te di pankrias nɔ ebul fɔ kɔntrol am, we kin mek di blɔd shuga lɛvɛl go ɔp.
• Dayabitis we pɔsin kin gɛt we i gɛt bɛlɛ:Dis na wan sik we kin kam we uman gɛt bɛlɛ. Risach pipul dεm biliv se di כmon dεm we di plasεnta de kכlכs de mek insulin rεsistεns. if di pankrias nכ ebul fכ win dis rεsistεns, di jεstεshכnal dayabεtis de divεlכp. Bɔt bɔku tɛm, dis kin bɛtɛ afta dɛn bɔn di pikin.

Apat frɔm dat, wan kayn dayabitis de we dɛn kin kɔl Maturity-onset diabetes of the young (MODY) . Dɛn kin kɔl dis bak wan sik we dɛn kɔl monojenik dayabitis . I kin kɔmɔt frɔm wan jɛnɛtik muteshɔn we kin pas to jɛnɛreshɔn ɛn i kin afɛkt di we aw di bɔdi de mek ɛn yuz insulin.

Wan kɔndishɔn we pɔsin kin gɛt we i gɛt bɔku insulin

Wan tumbu we nɔ kin bɔku we dɛn kɔl insulinoma kin mek di pankrias mek tumɔs insulin. Dis kin mek di blɔd shuga nɔ bɔku bɔku tɛm, sɔntɛnde i kin rili bad. Bɔku tɛm, dɛn kin mɛn dɛn insulinoma ya if dɛn du ɔpreshɔn.

Us kayn insulin de fɔ dayabitis?

Bɔku kayn insulin de fɔ mɛn dayabitis. Mɔs pan dɛn kin kam insay injɛkshɔn fɔm - ɔ tru nidul, pen ɔ pɔmp. Insulin dɛn de bak we dɛn kin inhal. If yu gɛt dayabitis, yu dɔktɔ go disayd di kayn ɛn di doz we fayn fɔ yu. Dɛn kin ajɔst di doz as nid de.

Dɛn kin sheb di kayn insulin dɛn mɔ bay aw dɛn kin wok kwik ɛn aw lɔng dɛn kin de na di bɔdi .

• Insulin we de wok kwik kwik wan: Dis kayn insulin kin bigin fɔ wok insay 5-20 minit ɛn i kin las fɔ lɛk 3-5 awa. I kin wok fayn wan to tu awa afta dɛn dɔn injɛkt am. Insulin glulisine na wan pan dɛn kayn tin ya. Insulin we dɛn inhal de insay dis kategori bak. Bɔku tɛm, dɛn kin it dɛn tin ya bifo dɛn it.
• Insulin we dɛn kin yuz ɔltɛm ɔ insulin we kin wok fɔ shɔt tɛm: Dɛn tin ya na Novolin R® ɛn Humulin R® . Dɛn kin bigin fɔ wok insay 30-45 minit afta dɛn injɛkt dɛn ɛn dɛn kin las fɔ lɛk 5-8 awa so. Dɛn kin mak pan 2-4 awa afta dɛn dɔn injɛkt dɛn.
• Insulin we de wok na di intamɛdiet: Dis kayn we kin tek lɛk tu awa so fɔ bigin fɔ wok. I kin wok fayn bitwin 4 ɛn 12 awa afta dɛn dɔn injɛkt am. I kin las fɔ lɛk 14-24 awa so. Isophane insulin (NPH) na wan pan dɛn kayn tin ya.
• Insulin we de te: Dis kayn insulin kin tek lɛk wan awa so fɔ rich na di blɔd ɛn bigin fɔ wok. I kin wok bεst bitwin 3 εn 14 awa afta dεn injεkt am. I kin las fɔ lɛk wan de so. Insulin glargine na ɛgzampul fɔ dis kayn.
• Ultra long-acting insulin: Dis kayn insulin de tek lεk siks awa fכ rich di bכdi εn i de aktif na di sem lεvεl fכ sεvεra awa (we min se i nכ de pik wan tεm). I kin tek lɛk tu dez so. Insulin degludec na wan pan dɛn kayn tin ya.

Impɔtant: Ɔltɛm fala yu dɔktɔ in instrɔkshɔn fɔ di kayn insulin, di doz, ɛn di we aw dɛn gi yu. Nɔ ɛva chenj yu insulin doz if yu nɔ go to dɔktɔ.

Ɛni bad bad tin dɛn de we pɔsin kin du we i gɛt insulin?

Di prɔblɛm we kin apin we pɔsin tek insulin na we di blɔd shuga nɔ bɔku (haypoglycemia) we kin kam bikɔs i tek bɔku insulin.

Apat frɔm dat, ɔda bad bad tin dɛn de we kin apin so ɔltɛm:

• di tin dεm we di skin kin du na di say dεm we dεn injεkt insulin: We dεn injεkt insulin bכku tεm na di sem εria, fεt kin bכku כnda di skin, fכ mek bכku. Ɔ, di fat kin brok ɛn mek dimples na di skin. Dɛn kɔl dis lokaliz lipodistrofi . Dis kin mek di insulin nɔ de tek bɔku tɛm. Na dat mek i impɔtant fɔ de chenj di say dɛn we dɛn de injεkt insulin ɔltɛm.
• Alɛji fɔ insulin: Sɔm pipul dɛn kin gɛt alɛji fɔ sɔm kayn insulin. Dis kin mek yu fil pen, bɔn, dɔn yu skin kin chenj, i kin it, ɛn swel rawnd di say we yu injɛkshɔn fɔ sɔm awa.
• Insulin antibodies: Na smɔl tɛm nɔmɔ, bikɔs di insulin we dɛn gi na do difrɛn smɔl frɔm di natura insulin we dɛn de mek na di bɔdi, wi bɔdi kin mek antibodies agens am. Dɛn antibodi ya kin mek di insulin we dɛn gi na do nɔ wok fayn. If na so i bi, yu go nid fɔ tek bɔku bɔku insulin.

Wetin na di bɛst ples fɔ injekt insulin?

Yu kin injekt insulin na bɔku say dɛn na yu bɔdi. in jεnarכl, di bεst ples fכ injεkt insulin na di ples dεm we yu gεt fεt (adipose tissue). Dɛn tin ya na:

• yu bεlε εria - bכt at le 2 inch (5 sεntimita) away frכm yu nεvεl.
• Di frɔnt ɔ di sayd dɛn na yu shɔl.
• Di bak pat pan yu ɔp an dɛn.
• Di tɔp pat pan yu bɔdi.

As wi bin dɔn tɔk, yu fɔ chenj di say dɛn we yu de injɛkt insulin fɔ mek yu nɔ gɛt prɔblɛm dɛn na yu skin. If yu injekt wan sayt tide, injekt am na difrɛn sayt di nɛks de. Yu kin aks yu dayabitis kia ɛn ɛdyukeshɔn spɛshal ɔ dɔktɔ fɔ no mɔ bɔt dis.

Yu tink se sɔntin de we dɛn kɔl nɔmal insulin lɛvɛl?

infakt, nכ "nכmal" de fכ insulin lεvεl. Dis na bikɔs ɔlman difrɛn, ɛn di insulin we yu nid kin difrɛn bad bad wan frɔm wan awa to ɔda awa ɔl di de. Bɔku tin dɛn de we kin afɛkt yu insulin lɛvɛl:

• Di kayn it ɛn di kayn it we yu de it (espɛshali it dɛn we gɛt kabɔhaydrɛt).
• Ustɛm yu de it ɛn aw ɔltɛm yu de it .
• Yu aktiviti lɛvɛl ɛn us kayn ɛksɛsayz yu de du (fɔ ɛgzampul, kardio ɔ weitliftin).
• Ilɛksɛf yu sik ɔ yu de strɛs .
• Yu wek ɔ yu de slip?
• Ɔda kayn ɔmon dɛn.
• Sɔm mɛrɛsin dɛn, lɛk kɔtikosterɔyd .

Dɔn bak, no standad tɛst nɔ de we de jɔs chɛk yu insulin lɛvɛl. Bɔku tɛm, dɛn kin chɛk di blɔd shuga lɛvɛl.

Pipul wae gɛt Tayp 2 Dayabitis stil nid insulin?

Nɔto ɔlman we gɛt tayp 2 dayabitis, bɔt sɔm pipul dɛn, nid insulin fɔ mɛn di sik fayn fayn wan.

Bɔrku ɔda kayn mɛrɛsin de fɔ tayp 2 dayabitis. Fɔ ɛgzampul, ɔral pils ɛn GLP-1 agonist injɛkshɔn . Dɛn mɛrɛsin ya de wok fɔ fɛt di insulin rɛsistɛns difrɛn we dɛn. Bɔt if insulin rɛsistɛns rili bad, dɛn mɛrɛsin ya nɔmɔ nɔ go du fɔ mek di blɔd shuga kɔntinyu fɔ gɛt wɛlbɔdi. Na da tɛm de dɛn nid insulin.

Aw lɔŋ pɔrsin wae gɛt shuga kin go wae nɔr gɛt insulin?

Pɔsin we gɛt dayabitis we de dipen pan insulin nid fɔ gɛt insulin we de kɔmɔt na do fɔ mek i kɔntinyu fɔ liv. If i nɔ de, wan prɔblɛm we kin mek pɔsin in layf de pan denja we dɛn kɔl Dayabitis-rilayt Kɛtoacidosis (DKA) kin kam.

DKA na wan prɔblɛm we kin apin wantɛm wantɛm ɛn we kin rili bad. I kin divɛlɔp insay 24 awa. I kin divɛlɔp kwik kwik wan if yu de vɔmit. I impɔtant fɔ kɔl dɔktɔ ɔ go na ɔspitul jɔs afta yu si di sayn dɛm fɔ DKA. If dɛn nɔ trit DKA, i kin kil pɔsin.

Di tin dɛn we impɔtant pas ɔl fɔ mɛmba frɔm wetin wi dɔn tɔk bɔt (Take-Home Message) .

So, yu go dɔn ɔndastand naw se insulin na impɔtant ɔmon we de ɛp wi bɔdi fɔ gɛt wɛlbɔdi ɛn fɔ wok fayn fayn wan.

• Insulin na wan natura ɔmon we wi pankrias de mek. i de εp fכ transpכt shuga (glucose) frכm di bכdi insay di sεl dεm εn mek εnεji.
• If yu bɔdi nɔ ebul fɔ mek insulin ɔ yuz am fayn, yu dɔktɔ kin gi yu insulin we de na do as tritmɛnt fɔ dayabitis.
• If dɛn dɔn gi yu insulin, yuz am jɔs lɛk aw yu dɔktɔ tɛl yu.Fɔ fala di doz, di tɛm, ɛn di say we dɛn gi di injɛkshɔn ɛksaktɔli.
• If yu gɛt sayn dɛm fɔ hapo glycemia (e.g., yu de swet, shek, yu de fɔdɔm, yu at de bit kwik kwik wan), tek sɔm shuga wantɛm wantɛm.
• If yu gɛt sɔm sayn dɛm fɔ dayabitik ketoacidosis (DKA) (e.g., yu de tɔsti pasmak, yu de pis bɔku tɛm, yu de nɔs, yu de vɔmit, yu bɛlɛ de pen, yu nɔ de ebul fɔ blo fayn, yu de smɛl lɛk frut) , go to dɔktɔ wantɛm wantɛm.

I rili impɔtant fɔ tek kia ɔf yu wɛlbɔdi biznɛs. If yu gɛt ɛni kwɛstyɔn bɔt insulin ɔ dayabitis, nɔ shek fɔ tɔk to yu dɔktɔ.

` Insulin, dayabitis, blɔd shuga, pankrias, ɔmon, dayabitis tritmɛnt, di kayn insulin