Dɛn dɔn gi yu dis mɛrɛsin fɔ blɔd prɛshɔn? Mek wi lan ɔltin bɔt ACE Inhibitors!

Wan prɔblɛm we bɔku pipul dɛn na Sri Lanka gɛt na ay blɔd prɛshɔn, ɔ "prɛshɔn" lɛk aw wi ɔl no am. So, yu dɔktɔ kin dɔn gi yu mɛrɛsin fɔ yu blɔd prɛshɔn, ɔ fɔ sɔm at sik. Pan di kayn mɛrɛsin dɛm we dɛn kin gi, ACE Inhibitors na wan klas we rili kɔmɔn ɛn rili impɔtant. If di nem fɔ yu mɛrɛsin na sɔntin lɛk Captopril, Enalapril, Lisinopril, den yu kin de yuz dis kayn mɛrɛsin bak. So tide, lɛ wi tɔk bɔt wetin na dɛn ACE Inhibitors ya, aw dɛn de wok insay wi bɔdi, ɛn wetin na di impɔtant tin dɛn we wi nid fɔ no we wi de yuz dɛn.

Fɔ tɔk am simpul wan, wetin na dɛn ACE Inhibitors ya?

di ful nem fכ dis na Angiotensin - Kכnvכt εnzym Inhibitors. Pan ɔl we di nem kɔmplikt smɔl, wetin i de du rili simpul. Fɔ ɔndastand dis, lɛ wi tɔk bɔt wan smɔl tin we kin apin na wi bɔdi.

Difrɛn ɔmon ɛn ɛnzaym dɛn de wok fɔ kɔntrol blɔd prɛshɔn na wi bɔdi. wan pan di men εnzym dεm dεn kכl am `ACE (Angiotensin-Converting Enzyme).` Dis `ACE` εnzym lεk sכmכl fכktri na wi bכdi. dis faktri de kכnvכlt di sכbstans `Angiotensin I` na wi bכdi to כda pawaful sכbstans we dεn kכl `Angiotensin II`.

Naw dis man we dɛn kɔl `Angiotensin II` na in de wok fɔ mek wi blɔd prɛshɔn go ɔp. I de du tu men tin dɛn:

1. Blɔd vesel dɛn kɔnstrikt (constrict): Jɔs lɛk we dɛn swɛt wata paip, di wata kin flɔ fast, we di blɔd vesel dɛn kin kɔnstrikt, di ples fɔ blɔd fɔ flɔ kin go dɔŋ, ɛn di prɛshɔn we de insay di vessel dɛn kin go ɔp.

2. I de mek sɔl ɛn wata nɔ kɔmɔt na di kidni: We bɔku sɔl ɛn wata de na di bɔdi, di blɔd volyum de go ɔp, ɛn dis kin mek di blɔd prɛshɔn go ɔp.

nכto dat nכmכ, dis `ACE` εnzym de brok dכn wan protin we dεn kכl `Bradykinin`, we de bεnεfit to wi bכdi εn de mek di bכdi vεsul dεm big. we yu tek wan ACE inhibito, biכs di `ACE` εnzym nכ de wok, mכr pan da gud protin we dεn kכl `Bradykinin` de de na di bכdi.

Fɔ tɔk am simpul wan, ACE inhibitors de stɔp fɔ mek tin dɛn we de mek blɔd prɛshɔn go ɔp ɛn nɔ de mek tin dɛn we de ridyus blɔd prɛshɔn nɔ lɔs. Dis tu tin we dɛn kin du kin ɛp fɔ kɔntrol blɔd prɛshɔn fayn fayn wan.

Fɔ us sityueshɔn dɛn dɔktɔ dɛn kin gi dis mɛrɛsin?

ACE Inhibitors nɔto jɔs wan mɛrɛsin fɔ blɔd prɛshɔn. Dɛn kin ɛp bak fɔ protɛkt di at ɛn kidni, so dɔktɔ dɛn kin gi dɛn fɔ difrɛn tin dɛn.

• Kɔntrol di ay blɔd prɛshɔn:Dis na di chans we impɔtant pas ɔl ɛn we dɛn kin yuz mɔ.
• Trit di at we nɔ de wok fayn: We di at nɔ ebul fɔ pamp inof blɔd, dis mɛrɛsin de ɛp fɔ ridyus di wok we di at de du ɛn ɛp am fɔ wok.
• Afta Hat Atak: Dɛn kin gi dis mɛrɛsin fɔ ɛp di at fɔ wɛl afta at atak ɛn fɔ mek i nɔ pwɛl mɔ.
• Protɛkt di kidni dɛm fɔ pipul dɛm wae gɛt shuga: Dayabitis kin pwɛl di kidni dɛm as tɛm de go. ACE inhibitors kin ɛp fɔ delay ɛn mek da damej de nɔ apin.
• Fɔ di wan dɛn we gɛt ay risk fɔ gɛt at atak ɛn strok: Dɛn kin gi dɛn tin ya bak fɔ mek dɛn tin ya nɔ apin to di wan dɛn we gɛt prɔblɛm.
• Fɔ ɔda kidni sik dɛm: Dɛn kin yuse dɛn tin ya bak fɔ sɔm kidni sik dɛm (lɛk `Nephrotic syndrome`, `Proteinuria`) we kin apin ivin pan pipul dɛm we nɔ gɛt dayabitis.

Wetin na di kayn ACE inhibitors we dɛn kin yuz mɔ?

Bɔku kayn ACE inhibitor dɛn de na di makit. Yu mɛrɛsin kin gɛt wan pan di nem dɛn we de dɔŋ ya. Yu fɔ mɛmba se pan ɔl we di jenɛrik nem fɔ di mɛrɛsin na di sem, di brand nem kin difrɛn bikɔs na difrɛn kɔmni dɛn mek am.

Aw a fɔ yuz dis mɛrɛsin?

Dɛn kin gi bɔku pipul dɛn wan ACE inhibitor wan tɛm insay di de. Bɔt sɔm pipul dɛn kin nid fɔ tek am tu tɛm insay di de. Dis na yu dɔktɔ fɔ disayd.

Wan tin we rili impɔtant na wetin fɔ du if yu mis wan doz. Imajin se yu fɔgɛt fɔ tek yu mɔnin doz. If yu mɛmba insay di de, tek am jɔs lɛk aw yu mɛmba. Bɔt if yu mɛmba di nɛks mɔnin, we min se i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, nɔ tek di doz we yu mis. Skip am ɛn jɔs tek di nɛks doz na di tɛm we dɛn dɔn sɛtul. Nɔ ɛva tek tu pils wan tɛm, wit di wan we yu fɔgɛt. If yu du dat, i kin mek yu blɔd prɛshɔn go dɔŋ tumɔs ɛn mek yu ed tɔn.

Wetin na di bɛnifit ɛn sayd ɛfɛkt dɛm fɔ dis mɛrɛsin?

ACE Inhibitors na wan klas ɔf drɔgs we dɔktɔ dɛn ɔlsay na di wɔl de abop pan fɔ bɔku rizin dɛn.

Men advantej dɛn

• I rili wok: Sayɛns risach dɔn pruv se dɛn tin ya kin rili ɛp fɔ kɔntrol blɔd prɛshɔn ɛn at sik.
• I de mek yu nɔ gɛt sik: Nɔto jɔs fɔ trit wan sik we dɔn de, bɔt i de ɛp bak fɔ mek yu nɔ gɛt at atak, strok, ɛn kidni sik tumara bambay.
• I kin wok wit ɔda mɛrɛsin dɛn: Sɔntɛnde, dɔktɔ dɛn kin gi yu wan pil we kin jɔyn wan ACE inhibitor ɛn ɔda blɔd prɛshɔn mɛrɛsin.
• Sef: Dɛn mɛrɛsin ya kin gɛt smɔl sayd ɛfɛkt. Siriɔs sayd ɛfɛkt nɔ kin bɔku, so dɛn kin yuz dɛn sef wan fɔ ɔl yu layf.

Sɔm sayd ɛfɛkt dɛn we pɔsin kin gɛt

Jɔs lɛk ɛni ɔda mɛrɛsin, dɛn tin ya kin mek sɔm pipul dɛn gɛt smɔl smɔl sayd ɛfɛkt.

Tin dɛn we yu fɔ tek tɛm wit we yu de yuz dis mɛrɛsin

Pipul wae nɔr fɔ tek dis mɛrɛsin

• Mama dɛn we gɛt bɛlɛ ɔ we de gi pikin dɛn bɛlɛ. (If yu de op fɔ bɔn pikin, tɛl yu dɔktɔ bifo tɛm.)
• Pipul wae bin dɔn gɛt angioedema (we de swel na dɛn fes).
• Pipul wae gɛt siriɔs kidni sik ɔr rεnal atεri stenɔsis.

Intarakshɔn wit ɔda mɛrɛsin dɛn

If yu de tek wan ACE inhibitor, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek (ivin vaytamɛn dɛn).

• Pen kil (NSAID): If dɛn yuz pen kil lɛk Ibuprofen ɛn Diclofenac bɔku tɛm, dɛn kin ridyus di ɛfɛktiv we di ACE inhibitors de du ɛn afɛkt di kidni dɛm.
• Mεdikeshכn dεm we de afekt di potashכm lεvεl: Sכm mεdikeshכn kin mek di potashכm lεvεl na di bכdi inkrεs we nכ nid (hyperkalemia).
• Sɔl ɛn sɔl we yu fɔ it: Kɔnsul yu dɔktɔ bɔt ɔmɔs sɔl yu fɔ it. Dɔn bak, mek shɔ se yu aks yu dɔktɔ bifo yu yuz "sɔlt sɔbstityuyt" we gɛt potashɔm.

Ustɛm yu fɔ go to dɔktɔ wantɛm wantɛm?

If ɛni wan pan dɛn bad bad sayn ya apin, go na di ɔspitul Imejɛnsi Dipatmɛnt (ETU) we de nia yu wantɛm wantɛm.

If yu de tek wan mɛrɛsin we de mek yu nɔ gɛt ACE, i go mɔs bi se yu dɔktɔ go tɛl yu fɔ du bɔku blɔd ɛn urine tɛst wan tɛm insay di ia fɔ chɛk aw yu kidni de wok ɛn di sɔl we de na yu blɔd. I rili impɔtant fɔ mek yu nɔ skip dɛn tɛst ya.