Sɔntɛnde, yu kin gɛt swɛlin wantɛm wantɛm na yu bɔdi? I kin bi angioedema!

Yu dɔn ɛva notis se yu lip dɛn kin swel wantɛm wantɛm, ɔ yu yay kin ful-ɔp? Sɔntɛnde, yu wan ol fes, ivin yu an ɛn fut kin swel. Na nɔmal tin fɔ fil fɔ fred smɔl we sɔntin lɛk dis apin. Bɔrku tɛm, dis kin kam wit wan sik wae dɛn kɔl angioedema . Mek wi tok abaut dis ditail, rili simpul, okay?

Wetin na Angioedema? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, Angioedema na we di tisu dɛn we de ɔnda wi skin kin swel, mɔ di dɛm, di layt we de insay di skin, ɔ di layers we de ɔnda wan myukɔs mɛmbran. Dis kin apin as riakshɔn to sɔntin. Yu go dɔn yɛri bɔt wan sik we dɛn kɔl ɔtikaria ɔ ayv . Bɔku tɛm, angioedema ɛn hayv kin apin togɛda, ɛn di tin dɛn we kin mek i apin kin rili fiba. Insay dɛn tu kes ya, wata kin kɔmɔt na wi smɔl smɔl blɔd vesel dɛn ɛn go insay di tisu dɛn, ɛn dis kin mek di say dɛn swel.

Angioedema kin bigin wantɛm wantɛm ɛn i kin stɔp insay wan ɔ tu dez. I kin afɛkt di lip ɛn rawnd di yay mɔ . Bɔt, imajin, if dis swɛlin afɛkt di say dɛn we wi de blo , i kin rili denja, ivin i kin mek wi day . So wi nid fɔ tek tɛm wit dat bak.

Wetin na di men kayn angioedema?

Bɔku kayn angioedema de. Difrɛn wɛlbɔdi ɔganayzeshɔn dɛn kin klas dɛn difrɛn we, bɔt in jɔnal, wi kin no sɔm men kayn dɛn.

1. Akyu alɛji angioɛdima

Dis na di kayn we we yu dɔn yɛri bɔt ɛn ɛkspiriɛns pas ɔl. I kin apin we yu gɛt sɔntin we yu alɛji fɔ . Dis kin bi sɔntin we yu dɔn it (it, drink), tek mɛrɛsin, ɔ tɔch (fɔ ɛgzampul, sɔntin we dɛn mek wit natura l rɔba lɛtɛks). I kin apin bak afta we insɛkt ɔ spayda dɔn bit am.

Akyu alɛji angioedema kin apin kwik kwik wan , bɔku tɛm insay sɔm minit to wan ɔ tu awa, afta yu dɔn gɛt di alɛrjen. Bɔku tɛm, dis swɛlin kin kam wit ayv.

2. Angioedema bikɔs ɔf wan nɔ-alɛji drɔg riakshɔn

Dis kayn angioedema nɔ kin apin wantɛm wantɛm afta yu tek mɛrɛsin. di men klas fכ dכg dεm we de mek dis nכn-alarjik riakshכn na angiotensin-kכnvεrt εnzym inhibito dεm , כ ​​ACE inhibito dεm כ ACEIs fכ sכt.Dɛn kin yuz dɛn mɛrɛsin ya fɔ mek di blɔd vesel dɛn big, fɔ mɛn di at prɔblɛm dɛn, ɛn fɔ mek di blɔd prɛshɔn go dɔŋ. Nɔn-steroidal anti-inflammatory drugs (NSAID) , lɛk ibuprofen ɛn naproxen, kin mek bak dis kayn angioedema.

3. Angioedema we wi nɔ no bɔt (Idiopathic angioedema) .

Di wɔd " idiopathic" min "we dɛn nɔ no bɔt di rizin." So i at fɔ fɛn wan patikyula kɔz fɔ dis kayn angioedema. Di swel kin apin na di fes, an, di trɔnk, ɛn leg. Sɔm pipul dɛn kin gɛt prɔblɛm wit dɛn imyun sistɛm bak ɛn dɛn kin gɛt strɛs.

4. Hɛridit angioɛdima (HAE) .

Dis na hereditary angioedema , we dɛn kin kɔl bak HAE fɔ shɔt tɛm. Dis na sɔntin we yu kin gɛt frɔm yu mama ɛn papa tru yu jin. Pikin dɛn kin gɛt am ilɛksɛf na wan mama ɔ papa nɔmɔ gɛt di jin, ɔ ivin if dɛn gɛt di sik. sכm pipul dεm kin gεt dis kayn angioedema bak bikoz fכ di spontan jεnεtik mכtεshכn dεm. Dɛn se lɛk 1 pan ɛvri 50,000 pipul dɛn kin gɛt dis kayn hereditary angioedema (HAE). tri men tכp dεm de fכ dis, εvri wan de riliyt in sכm we to di lεvεl dεm fכ C1 protin εn/כ C1 εsterase inhibito na wi bכdi.

5. Akwyayz C1 inhibito dεfisiεns angioεdima

Dis kin mek bak angioedema, bɔt i nɔ kin kɔmɔt frɔm am. Acquired min se yu nɔr bɔn wit di deficiency, bɔt yu de divɛlɔp am leta na yu layf. Lɛk ɔda kayn, dis kayn angioedema kin afɛkt yu larynx, ɔ windpaip, ɛn i kin mek yu swɛt. if yu gεt kכndyushכn lεk B-sεl limfoma, dεn kכl dis kכndyushכn Acquired C1 inhibitor deficiency.

6. Angioedema we kin kam bikɔs ɔf di vaybreshɔn (Vibratory angioedema) .

insay dis kכndishכn, di swεla de kכz fכ kכntinyu fכ vaybreshכn. Fɔ ɛgzampul, dis kin apin we yu de rayd motoka, rɔn, jok, mek yu masaj am tranga wan, ɔ du ɔda tin dɛn we tan lɛk dis. Vibratory angioedema na ɔda kayn sik we nɔ kin apin so ɔltɛm we dɛn kɔl chronic inducible urticaria . insay am, di hayv dεm de sho fכ ansa to tin dεm we de kכmכt na do lεk kol, כt, wata, prεshכn, כ vaybrεshכn. di welt dεm we de it kin kכntinyu εn kin las fכ lεk siks wik.

Udat dɛn kin gɛt angioedema?

Infakt, ɛnibɔdi kin gɛt angioedema. Dɛn se bitwin 20% ɛn 25% pan di pipul dɛm na Amɛrika go gɛt angioedema ɛn/ɔ ɔtikaria at le wan tɛm insay dɛn layf. So dis kɔndishɔn kin kɔmɔn na Sri Lanka bak.

Wetin na di sayn dɛm fɔ angioedema? Aw yu no dɛn?

Di men sayn dɛm fɔ angioedema na:

• Facial swelling or puffiness , mɔ arawnd di yay ɛn mɔt, inklud di lip ɛn tɔng. Imajin se yu wek na mɔnin ɛn wantɛm wantɛm yu lip dɛn so swel dat i tan lɛk se i nɔ izi fɔ tɔk.
• If yu intestinal dɛn inflam, yu kin gɛt prɔblɛm wit di dijestiv . Dis inklud bɛlɛ pen, dayarɛa, nɔs, ɛn vɔmit.
• Di an, fut, ɔ di say dɛn we di bɔdi kin swel.
• We yu blɔd prɛshɔn chenj i kin mek yu gɛt tin dɛn lɛk fɔ tɔn yu ed ɔ fɔ fɔdɔm .
• We yu mɔt, yu trot, ɔ di say dɛn we yu de blo swel, dat kin mek i nɔ izi fɔ blo ɛn tɔk. Dis na di tin we denja pas ɔl. If sɔntin lɛk dis apin, na mɛdikal imejensi. Yu nid fɔ go na ɔspitul wantɛm wantɛm!

Di tin we impɔtant pas ɔl: If yu trot swel ɛn yu fil lɛk se yu gɛt prɔblɛm fɔ blo, i nɔto jok. Go to dɔktɔ wantɛm wantɛm.

Wetin mek angioedema kin apin? Wetin na di tin dɛn we kin mek i apin?

Di tin dɛm wae kin mek yu gɛt angioedema kin difrɛn difrɛn wan bay di kayn angioedema wae yu gɛt. Bɔt di tin we kin mek pɔsin gɛt alɛji pas ɔl na alɛji . Bɔrku kayn alɛji de wae kin mek pɔrsin gɛt am:

• Fɔd alɛji: Mɔ milk, eg, nɛt lɛk kash, ɛn sifud lɛk shɔɛl na dɛn kin mek dis apin.
• Alɛji fɔ mɛrɛsin: Antibayɔtik lɛk penisilin ɛn sɔlfa drɔgs, nɔ-stɛroyd anti-inflammatory drɔgs (NSAID), ɛn kɔntrast midia we dɛn kin yuz fɔ sɔm imej tɛst dɛn kin mek dis apin. Dɛn kayn alɛji ya kin mek yu gɛt ayv.
• Vɛnom: Na pɔyzin we insɛkt dɛn kin it, ɛn nɔto bɔku tɛm animal dɛn lɛk di brawn reklɔs spayda kin kɔmɔt.
• Natural rubber latex: Latex na tin we dɛn kin yuz fɔ mek tin dɛn lɛk glɔv, balyɔn, kɔndɔm, ɛn mɛrɛsin kateta. Yu dɔktɔ go dɔn aks yu if yu gɛt alɛji fɔ lɛtɛks.

כda tin dεm we kin mek i apin na di prכblεm dεm we dεn kin gεt wit di C1 inhibito protin, di rεakshכn dεm we de kכmכt wit di drog we de apin we yu nכ it כ rεsh (dεn tin ya nכto tכpik alerji), εn di muvmεnt dεm we dεn de shek.

Yu tink se Angioedema kin pas?

Nɔ, nɔto so atɔl.Yu nɔ go ebul fɔ kech angioedema frɔm ɔda pɔsin, ɛn yu nɔ go ebul fɔ spre am to ɔda pɔsin. I nɔto sik we pɔsin kin pas.

Aw yu kin no se yu gɛt angioedema? Wetin dɔktɔ dɛn kin luk fɔ?

I kin tranga fɔ no uskayn kayn angioedema yu gɛt. Yu dɔktɔ go fɔs chɛk yu bɔdi, bɔt bɔku tɛm di swɛlin kin izi fɔ si. Dɔn dɛn go aks yu sɔm kwɛstyɔn dɛn:

• Ustɛm di swɛlin bigin?
• Yu it, drink, tek, ɔ tɔch ɛnitin we yu tink se na in mek di riakshɔn?
• Us mɛrɛsin ɛn sɔpɔtmɛnt dɛn yu de tek naw?
• Yu tink se pipul dɛn dɔn ɛva biev lɛk dis bifo?
• Ɛni ɔda pɔsin na yu famili dɔn gɛt swel lɛk dis?

Apat frɔm we yu aks dɛn kwɛstyɔn ya, yu dɔktɔ kin ɔda fɔ du blɔd tɛst ɔ fɔ tɛst yu skin fɔ chɛk if yu gɛt alɛji , ɔ fɔ du blɔd tɛst fɔ chɛk fɔ angioedema we gɛt fɔ du wit di C1 inhibitor protein.

Wetin na di tritmɛnt fɔ Angioedema?

Di tritmɛnt fɔ angioedema kin difrɛn difrɛn wan bay di kayn we aw yu gɛt.

• Fɔ siriɔs alɛji , yu dɔktɔ kin gi yu wan injɛkshɔn we dɛn kɔl epinephrine we yu kin kip wit yu ɔltɛm. Yu fɔ gi yusɛf dis injɛkshɔn we yu kɔl 911 (1990 na Sri Lanka) we yu gɛt imejensi.
• Fɔ alɛji angioedema , yu dɔktɔ kin gi yu antihistamin ɔ stɛroyd . Dɛn kin tek dɛn tin ya as pils, as wata (we dɛn kin tek bay mɔt), ɔ dɛn kin gi dɛn insay di bɛlɛ.
• If yu gɛt non-allergic drug reaction , yu dɔktɔ go fɛn ɔda we fayn fɔ yuz pas di mɛrɛsin we de mek yu swel. Nɔ ɛva stɔp fɔ tek yu mɛrɛsin if yu dɔktɔ nɔ advays yu.

Di mɛrɛsin dɛn we yu kin yuz na os na fɔ put ays fɔ mek yu nɔ swel, fɔ was kol, ɛn fɔ put kol wet klos na di say we yu swel. Dɛn tin ya kin wok fayn fɔ di swɛlin we de na di say we yu de, fɔ swel ɔlsay na di lip, ɔ fɔ di yay we ful-ɔp.

If yu gɛt hereditary, idiopathic, ɔ acquired C1 inhibitor deficiency angioedema , i go mɔs bi se dɛn go rifer yu to spɛshal dɔktɔ. Sɔm pan di mɛrɛsin dɛm wae dɛn kin yuse fɔ trit ɔr nɔr gɛt hereditary angioedema (HAE) na:

• C1 εsterεz inhibito (rεkombinεnt) (Ruconest®) .
• C1 inhibito (mɔtalman) (Berinert®, Cinryze®, Haegarda®)
• Ekalantayd (Kalbitor®) we dɛn kɔl .
• Ikatibant (Firazyr®) we dɛn kɔl .
• Lanadelumab (Takhzyro®) we de na di bɔdi.
• Berotralstat (Orladeyo®) we de na di wɔl.

Yu tink se we dɛn de fɔ mek yu nɔ gɛt angioedema?

Yɛs, sɔm we dɛn de.

• If yu gɛt angioedema , we gɛt fɔ du wit alɛji , yu kin avɔyd am bay we yu nɔ it it, mɛrɛsin, ɔ ɔda tin (trig) we kin mek yu gɛt alɛji.
• If yu gɛt non-allergic angioedema we yu de tek ACEI mɛrɛsin (ACE inhibitors) , yu fɔ tɔk to yu dɔktɔ bɔt aw fɔ chenj to ɔda mɛrɛsin.

Wetin pɔsin we gɛt angioedema kin ɛkspɛkt?

Bɔku pan di kes dɛm we dɛn kin gɛt angioedema nɔ kin las fɔ lɔng tɛm . Bɔku tɛm, dɛn kin disayd fɔ dɛnsɛf. Bɔt if i siriɔs, dɛn nid tritmɛnt fɔ mek di say we di briz de blo opin.

Yu tink se Angioedema kin kil pɔsin? Yu tink se dis denja?

Fɔ sɔm pipul dɛm, alɛji angioedema kin mek dɛn gɛt wan sik we dɛn kɔl anafylaksis - we di aywe ɛn di lɔng dɛn kin swel bad bad wan. Dis kin mek pɔsin in layf de pan denja . Dɔktɔ dɛn kin advays pipul dɛn we gɛt dis sik fɔ kɛr epinephrine we dɛn kin injɛkt (EpiPen®, Auvi-Q®, Adrenaclick® ɛn ɔda brand dɛn) fɔ trit bad bad alɛji.

Ilɛk wetin na di kɔz, angioedema we de afɛkt di aywe na ɔltɛm mɛdikal imejensi. So, dɛn nid fɔ gɛt tritmɛnt kwik kwik wan. Sɔntɛnde, i kin nid fɔ du ɔpreshɔn we dɛn kɔl tracheostomy (we de mek wan opin na di briz paip) fɔ ɛp fɔ mek i ebul fɔ blo.

If a gɛt angioedema, aw a go tek kia ɔf misɛf?

If yu gɛt angioedema, yu fɔ avɔyd tin dɛn we kin mek yu gɛt alɛji . If yu dɔktɔ gi yu mɛrɛsin fɔ mek yu nɔ gɛt ɔda sik, tek dɛn jɔs lɛk aw dɛn tɛl yu. If dɛn dɔn tɛl yu fɔ kɛr epinephrine we dɛn kin injɛkt , mek shɔ se yu gɛt am wit yu ɔltɛm. Tich yu fambul ɛn padi dɛn aw fɔ yuz am.

Ustɛm a fɔ go to dɔktɔ?

If yu gɛt siriɔs alɛji ɛn swel afɛkt yu aywe, kɔl 1990 (imejɛnsi ambulans savis) wantɛm wantɛm.

Insay kes dɛm we nɔr kin siriɔs, if yu kɔntinyu fɔ gɛt angioedema, go to yu dɔktɔ. Dɛn kin tɔk bɔt aw fɔ mek dɛn nɔ gɛt dis sik. Ɔda tritmɛnt dɛn we yu kin tek na antihistamin ɛn stɛroyd we yu kin it. Idiopathic, i at fɔ tritSɔm dɔktɔ dɛn dɔn yuz wan monoklɔnal antibodi we dɛn kɔl Omalizumab (Xolair®) fɔ angioedema (idiopathic angioedema).

Fɔ dɔn, di tin dɛn we impɔtant pas ɔl we wi fɔ mɛmba

If yu yay, yu lip, ɔ yu an fil se yu dɔn swel, i kin bi wan tin we de apin to yu skin we dɛn kɔl angioedema. Dis kin apin mɔ if yu gɛt alɛji. Kip rayt bɔt ustɛm ɛn ustɛm dis kin apin, ɛn lan fɔ avɔyd di tin dɛn we yu nɔ kin lɛk fɔ du. If yu no se ɔda pipul dɛn na yu famili dɔn gɛt dɛn kayn tin ya, tɛl yu dɔktɔ. I kin tɛl yu fɔ du tɛst fɔ si if di sik de rɔn na yu famili. If yu gɛt angioedema bikɔs ɔf alɛji, i rili impɔtant fɔ kip wan epinephrine we dɛn kin injɛkt na yu an, bikɔs if yu swel na yu aywe dɛn kin mek yu stɔp fɔ blo. Nɔ fred, bɔt i fayn fɔ no bɔt dis ɛn tek di step dɛn we yu nid.

` Angioedema, swel, alɛji, skin sik, imejensi kia, epinephrine, ɔtikaria