Sɔmtɛm, pɔrsin wae gɛt dis sik wae de kam wit Pakinson nɔr kin ebul fɔ kɔntrol aw in bɔdi de muv wantɛm wantɛm, in bɔdi kin stif , ɛn dɛn kin bigin fɔ shek. Wi de kol dis wan ‘off’ episod. I fil lɛk se dɛn dɔn ‘ɔf’ wan switch. So tide wi go tɔk bɔt wan spɛshal mɛrɛsin we dɛn kin yuz fɔ gi pɔsin kwik rilif pan tɛm lɛk dis. Dat na wan tablɛt we de ɔnda di langwej we dɛn kɔl apomorphine.
Wetin na dis Apomɔfin?
Fɔ tɔk am simpul wan, dis na mɛrɛsin we dɛn kin gi fɔ kɔntrol di sayn dɛm fɔ di sik we dɛn kɔl Pakinsin. Wan kemikal we dɛn kɔl dopamine de ɛp fɔ kɔntrol di muvmɛnt ɛn kɔdineshɔn na wi bren. Tink bɔt dis dopamin as mɛsenja we de kɔntrol aw wi bɔdi de muv. Insay di sik we dɛn kɔl Parkinson, di amɔnt fɔ dis mɛsenja kin go dɔŋ na di bren. Na da tɛm de de sayn dɛm lɛk fɔ shek shek ɛn fɔ stiff de apia.
So wetin dis drɔg, Apomorphine, de du na fɔ akt lɛk da dopamine mɛsenja we dɔn dɔn ɛn i de ɛp di bren fɔ sɛn mɛsej fayn fayn wan bak. Dis kin mek di sik wae de kam pan pɔrsin kin shɔt kwik kwik wan ɛn de bɔdi kin fil fayn smɔl.
Dis mɛrɛsin de kam bak ɔnda di brand nem KYNMOBI. Bɔt bikɔs dɛn kin yuz am fɔ ɔda tin dɛn bak, i go fayn fɔ mek yu tɔk to yu dɔktɔ bɔt ɛnitin we de mɔna yu.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
I rili impɔtant fɔ mek yu dɔktɔ no yu kɔmplit mɛdikal histri bifo yu gi yu dis mɛrɛsin. Mek shɔ se yu tɛl yu dɔktɔ if yu gɛt ɛni wan pan di sik dɛn we de dɔŋ ya.
- If yu de gɛt diziz ɔ yu de fɔdɔm ɔltɛm: Sɔntɛnde dis mɛrɛsin kin mek yu blɔd prɛshɔn smɔl. So if yu dɔn gɛt dis prɔblɛm, i impɔtant fɔ tɔk bɔt am.
- At sik: If yu gɛt at sik, mɔ we yu at nɔ de bit ɔltɛm.
- Lɔw blɔd prɛshɔn: If yu blɔd prɛshɔn smɔl.
- If yu dɔn gɛt strok.
- Kidni ɔ liva sik: If yu kidni ɔ liva nɔ de wok fayn.
- Lɔng sik: I nɔ kin izi fɔ blo lɛk asma.
- Prɔblɛm wit yu maynd: Kɔndishɔn lɛk pwɛl hat.
- If yu gɛt slip we yu nɔ ebul fɔ kɔntrol insay di de.
- If yu na pɔsin we de drink bɔku tɛm.
- If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ.
- If yu na mama we de gi pikin in bɛlɛ.
- If yu gɛt ɔda alɛji: Tɛl yu dɔktɔ if yu gɛt ɛni alɛji to apomorphine, sulfites, ɔda mɛrɛsin, it, prɛzɛvɛtiv, ɔ day.
I rili impɔtant fɔ yu yon sef fɔ tɛl di dɔktɔ we yu nɔ ayd dis infɔmeshɔn.
Aw ɛksaktɔli yu kin yuz dis mɛrɛsin?
Di we aw fɔ yuz dis rili simpul, bɔt na sɔntin we dɛn nid fɔ du fayn fayn wan.
1. Tek am di rayt tɛm: Yuz dis as yu gɛt ‘ɔf’ ɛpisod, jɔs lɛk aw yu dɔktɔ dɔn tɛl yu.
2. Rimov am na di paket: Kip di mɛrɛsin insay di fɔyl paus te yu rɛdi fɔ tek am.
3. An fɔ dray: Mek shɔ se yu an dray bifo yu ol di mɛrɛsin. I kin mɛlt if yu tɔch am wit wet an.
4. Put di fim ɔnda yu tɔng: Put di fim ɔnda yu tɔng. Alaw am fɔ sɔlv ɛn yu bɔdi tek am.
5. Nɔ chew, brok, ɔ krɔs: Nɔ chew, brok, ɔ krɔs dis mɛrɛsin na yu mɔt. I fɔ sɔlv ɔnda yu tɔŋ.
Nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm we yu nɔ go to yu dɔktɔ. Dis kin mek yu gɛt siriɔs sayd ɛfɛkt ɛn i kin mek yu sik wɔs.
Wetin fɔ du if yu tek di mɛrɛsin pasmak?
If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, nɔ panik. Go na di ɔspitul we de nia yu Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm. Ɔ, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital .
Wetin a go du if a mis wan doz?
Dis nɔto mɛrɛsin fɔ tek di sem tɛm ɛvride. Dɛn kin yuse am nɔmɔ di tɛm we ‘ɔf’ episɔd, we di sik dɛn we de kam pan Pakinson kin bɔku wantɛm wantɛm. So ‘missed a dose’ nɔ de aplay ya. Bɔt if yu tek di fɔs doz di tɛm we yu de ‘ɔf’ ɛn yu sik nɔ de bɛtɛ, nɔ tek di sɛkɔn doz da tɛm de. Tɔk to yu dɔktɔ bɔt dis.
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin
Dis na pat we rili impɔtant. Sɔm mɛrɛsin kin mek yu gɛt denja we yu tek am wit Apomorphine.
| Nɔ ɛva tek dis mɛrɛsin wit am! | |
|---|---|
| Cisapride we dɛn kɔl Cisapride | Pimozayd we dɛn kɔl Pimozide |
| Dronedarone we gɛt di sik | Tioridazin we dɛn kɔl Tioridazin |
| Ketokonazɔl we dɛn kɔl | Levoketoconazole we gɛt di sik |
| Sɔm mɛrɛsin fɔ vɔmit ɛn nɔs (e.g., dolasetron, granisetron, ondansetron, palonosetron) . | |
| Tek tɛm bad bad wan we yu de yuz dɛn tin ya wit | |
|---|---|
| Rum | Pils fɔ slip |
| Sɔm mɛrɛsin fɔ pwɛl hat (e.g. amitriptyline) . | Di tin we de mek di mɔsul dɛn rilaks |
| Sɔm opioid fɔ pen ɔ kɔf | Naytroglisrin we dɛn kɔl |
| Sɔm mɛrɛsin fɔ alɛji (Antihistamines) . | Mɛrɛsin dɛn lɛk Haloperidol ɛn Metoclopramide |
Dis list nɔ kɔmplit, so tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn, tradishɔnal mɛrɛsin, ɛbul mɛrɛsin, ɛn ivin ɛbul supamakit) .
Tin dɛn we yu fɔ tek tɛm wit we yu de tek dis mɛrɛsin
- Nɔs ɛn vɔmit: Dis mɛrɛsin kin mek yu nɔs ɛn vɔmit. Sɔntɛnde, i kin rili bad. Yu dɔktɔ go gi yu wan ɔda mɛrɛsin fɔ dis. Nɔ tek mɛrɛsin we yu kin bay fɔ mek yu nɔ fil bad. Nɔto ɔl di mɛrɛsin dɛn we de mek pɔsin nɔ fil fayn, de wok wit dis mɛrɛsin.
- Fɔ slip wantɛm wantɛm:Dis rili impɔtant. We yu tek dis mɛrɛsin, yu kin slip wantɛm wantɛm ɛn nɔ wɔn yu. Imajin se yu de drayv motoka, it, ɔ tɔk to pɔsin ɛn yu slip we yu nɔ no. Dis na tin we rili denja. So , nɔ drayv ɔ yuz mashin te yu no aw dis mɛrɛsin de afɛkt yu. If yu gɛt dis, tɛl yu dɔktɔ wantɛm wantɛm.
- Alkol: If yu tek dis mɛrɛsin wit rɔm, dat kin mek yu gɛt diziz, fɔdɔm, ɛn slip wantɛm wantɛm.
- Nitroglycerin: If yu de tek nitroglycerin sablingually fɔ at sik, if yu tek dɛn tu mɛrɛsin ya togɛda, i kin mek yu blɔd prɛshɔn go dɔŋ bad bad wan. So, if yu nid fɔ tek naytroglisrin, ledɔm fɔs . Dɔn tek di mɛrɛsin. Stay ledɔm fɔ at le 45 minit afta yu dɔn tek di mɛrɛsin.
Us bad bad tin dɛn kin apin we pɔsin kin si?
Lɛk ɛni mɛrɛsin, dis wan kin gɛt sayd ɛfɛkt. Sɔm siriɔs, sɔm kɔmɔn.
| Siriɔs sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ wantɛm wantɛm | |
|---|---|
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na yu fes, lip, tong, yay, i nɔ izi fɔ blo ɔ swɛla. |
| Fɔ slip wantɛm wantɛm | Fɔ slip insay di de we yu nɔ wɔn yu . |
| Lɔw blɔd prɛshɔn | Sivɛri diziz, fɔdɔm, blurred vishɔn. |
| Di chenj dɛn we de apin na di at rit | Fɔ fil lɛk se yu at de bit fast ɔr nɔr de bit ɔltɛm, yu chɛst de pen, yu nɔr de ebul fɔ blo. |
| Di chenj dɛn we pɔsin kin gɛt na in maynd | Fɔ si ɔ yɛri tin dɛn we nɔ de (hallucinations), chenj dɛn we nɔ kɔmɔn pan aw pɔsin de biev. |
| Impul dɛn we pɔsin nɔ ebul fɔ kɔntrol | Di tin dɛn we pɔsin nɔ ebul fɔ kɔntrol fɔ du tin dɛn lɛk fɔ ple gem, fɔ it pasmak, fɔ du mami ɛn dadi biznɛs, ɛn fɔ spɛnd mɔni we nɔ nid fɔ du. |
| Ɛmolaytik anemia | Fɔ fil taya we nɔ kɔmɔn, diziz, i nɔ izi fɔ blo, yu urine dak, yu skin ɔ yu yay de yɔlɔ. |
| Sayd ɛfɛkt dɛm we dɛn kin si, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Diziz we pɔsin kin gɛt | Di we aw pɔsin kin slip |
| Ed de at | Nɔs ɛn vɔmit |
| Usay di mɛrɛsin bin de, dat na ɔnda di tɔŋ, na de pen, inflamɛns, ɔ sɔri de. | |
Aw fɔ kip di mɛrɛsin?
- Kip fa frɔm pikin ɛn animal dɛn we yu de mɛn. Dis rili impɔtant.
- Stɔr na rum tɛmpracha (bitwin 20-25 digri sɛlshiɔs).
- Kip di mɛrɛsin insay di fɔyl paket te i rɛdi fɔ yuz.
- Trowe di mɛrɛsin we dɔn pas.
Aks yu dɔktɔ aw fɔ trowe di mɛrɛsin dɛn we yu nɔ yuz ɔ we dɔn pas, fayn fayn wan.
Mɛsej we dɛn kin kɛr go na os
- Apomorphine na sablingual tablεt we de gi rεpid simptom kכntrכl di tεm we di ‘off’ fεz dεm fכ di Pakinsin sik.
- Bifo yu yuz dis mɛrɛsin, tɛl yu dɔktɔ bɔt ɔl yu wɛlbɔdi prɔblɛm ɛn ɔl ɔda mɛrɛsin dɛn we yu de tek.
- Yu kin slip bak we yu nɔ no we yu de tek dis mɛrɛsin. So, nɔ du tin dɛn we nid fɔ de wach, lɛk fɔ drayv, te yu no aw dis mɛrɛsin de afɛkt yu bɔdi.
- Fɔ mek yu nɔ gɛt diziz ɛn fɔdɔm, grap ɔltɛm we yu sidɔm ɔ ledɔm.
- Yu fɔ no bɔt siriɔs sayd ɛfɛkt (lɛk alɛji, chenj na yu at rit, chenj na yu maynd) we nid fɔ go to dɔktɔ wantɛm wantɛm.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva sheb am wit ɔda pipul dɛn.
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