We dɔktɔ gi pɔsin nyu mɛrɛsin to pɔsin we de fɛt kansa, i nɔmal fɔ lɛ pɔsin fred smɔl ɛn want fɔ no mɔ. "Wetin go apin wit dis?", "Aw a go yuz dis?", "Ɛni sayd ɛfɛkt de?" I go mɔs bi se yu gɛt bɔku kwɛstyɔn dɛn na yu maynd. Na dat mek wi de ya fɔ tɔk bɔt di mɛrɛsin we dɛn dɔn gi yu, we na Crizotinib, insay wan simpul, izi fɔ ɔndastand. Imajin dis lɛk se yu padi ɔ yu fambul de tɛl yu bɔt am.
Fɔ tɔk am simpul wan, wetin na Crizotinib?
Crizotinib na wan patikyula mɛrɛsin we dɛn kin yuz fɔ trit sɔm kayn kansa. Insay wi kɔntri, dɛn kin si dis mɛrɛsin mɔ ɔnda di brand nem XALKORI . Dis na drɔg we de wok lɛk mishɔl we de nak di say we i want fɔ go.
Tink bɔt kansa sɛl dɛn as bad plant dɛn we de gro we yu nɔ ebul fɔ kɔntrol. Wan spɛshal prɔtin de we de ɛp dɛn bad plant ya fɔ gro ɛn skata. I tan lɛk paip we de gi wata to da bad plant de. Dis drɔg we dɛn kɔl Crizotinib de blok da paip de, da spɛshal prɔtin de. Dɔn di ebul we di kansa sɛl dɛn kin ebul fɔ gro ɛn skata ɔlsay na di bɔdi kin ridyus, ɔ i kin stɔp kpatakpata. Dis na aw dis mɛrɛsin de ɛp fɔ kɔntrol kansa.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin dis mɛrɛsin
Crizotinib na wan pawaful mɛrɛsin, so i impɔtant fɔ mek yu dɔktɔ gɛt kɔmplit pikchɔ bɔt yu wɛlbɔdi bifo yu bigin dis tritmɛnt. Nɔ ayd ɛnitin, ivin di smɔl smɔl tin dɛn. Ɛvri smɔl tin we yu go sheb go ɛp yu dɔktɔ fɔ trit yu sef wan.
Yu sef fɔs, so mek shɔ se yu tɔk bɔt dis infɔmeshɔn klia wan wit yu dɔktɔ.
Luk di tebul we de dɔŋ ya. If ɛni wan pan dɛn tin ya apin to yu, mek shɔ se yu tɔk bɔt am.
| Di kayn infɔmeshɔn we dɛn gɛt | Wetin fɔ tɛl yu dɔktɔ |
|---|---|
| Di tin dɛn we de apin naw na di mɛrɛsin |
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| Alɛji dɛn we pɔsin kin gɛt | If yu gɛt alɛji fɔ Crizotinib ɔ ɛni ɔda mɛrɛsin, it, ɔ tin dɛn we de mek yu nɔ pwɛl. |
| Bεlε εn we i de gi pikin in bεlε |
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Aw fɔ yuz di mɛrɛsin kɔrɛkt wan?
Fɔ mek yu gɛt di bɛst pan dis mɛrɛsin, i rili impɔtant fɔ yuz am kɔrɛkt wan.
- Swɛla nɔmɔ: Dis mɛrɛsin kin kam lɛk kapsul. Nɔ brok am, krɔs am, ɔ it am. Swɛla am ɔl wit wan glas wata.
- Na di rayt tɛm: Mek am yu abit fɔ tek yu mɛrɛsin di sem tɛm ɛvride. Tek di kɔrɛkt doz, jɔs lɛk aw yu dɔktɔ tɛl yu.
- Wit ɔ atɔl it: Dɛn kin tek dis mɛrɛsin bifo ɔ afta it. Bɔt sɔm pipul dɛn kin gɛt smɔl bɛlɛ at ɔ nɔs we dɛn tek am we dɛn nɔ it. If dis apin, tek di mɛrɛsin wit sɔm it.
- Nɔ tek wit grep jus: Dis rili impɔtant. Nɔ tek dis mɛrɛsin wit grep ɔ grep jus. Dis na bikɔs di tin dɛn we de insay grep jus kin chenj di we aw di bɔdi de tek di mɛrɛsin ɛn mek di sayd ɛfɛkt dɛn bɔku.
- If yu vɔmit: If yu vɔmit afta yu dɔn tek di mɛrɛsin, nɔ tek ɔda doz. Skip da tɛm de ɛn tek yu nɛks doz na di tɛm we dɛn dɔn sɛtul.
- If yu mis wan doz:
- If i pas 6 awa te yu tek di nɛks doz, tek di doz we yu mis jɔs lɛk aw yu mɛmba.
- Bɔt if i nɔ rich 6 awa te yu tek di nɛks doz, skip di doz we yu mis. Tek yu nɛks doz na di tɛm we dɛn dɔn sɛtul. Nɔ ɛva tek tu dos wan tɛm.
- Nɔ stɔp fɔ tek di mɛrɛsin: Ilɛksɛf yu gɛt sayd ɛfɛkt ɔ fɔ ɛni ɔda rizin, nɔ stɔp fɔ tek di mɛrɛsin ɔ chenj di doz if yu dɔktɔ nɔ advays yu.
Ovados fɔ yuz am
If yu gɛt ɛni saspek se yu aksidɛntli tek mɔ mɛrɛsin pas aw yu tink, go na di ɔspitul Imejɛnsi Dipatmɛnt (ETU) we de nia yu wantɛm wantɛm. Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
Ɔda tin dɛm wae kin intarakt wit dis mɛrɛsin (Interactions) .
Ɔda mɛrɛsin dɛn we yu de tek kin intarakt wit Crizotinib ɛn mek yu gɛt ɛfɛkt we yu nɔ want. So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (mɛrɛsin fɔ ɔda sik dɛn, vaytamɛn, nyutrishɔn sɔpɔtmɛnt, Sinhala mɛrɛsin, Ayurveda mɛrɛsin).
Tek tɛm mɔ wit dɛn mɛrɛsin ya bikɔs dɛn kin miks wit Crizotinib.
| Drugs wae nɔr fɔ ɛva tek wit Crizotinib | |
|---|---|
| Sɔm mɛrɛsin fɔ fungal infɛkshɔn | Eg: Kεtokonazכl, Itrakonazכl, Flukonazכl, Posakonazכl |
| Ɔda patikyula mɛrɛsin dɛn | Drug dɛn lɛk Dronedarone, Pimozide, Thioridazine, Saquinavir, Flibanserin, Levoketoconazole, Lomitapide, Lonafarnib, Pakritinib. |
| Ɔda drɔgs ɛn tin dɛn we kin mek pipul dɛn gɛt cham-mɔt | |
| Grepfruit Jus we dɛn kɔl | Dis kin chenj di we aw di mɛrɛsin de wok. |
| Drɔg dɛn we de mek yu at rit smɔl | Fɔ ɛgzampul: Digɔksin, Mɛtoprolɔl, Prɔpranɔlɔl, Diltiazem, Klɔnidin |
| Ɔda drɔgs dɛn we de afɛkt di at ritm | Aks yu dɔktɔ bɔt dis. |
Tin dɛn we yu fɔ tek tɛm wit we yu de tek di mɛrɛsin
I rili impɔtant fɔ pe atɛnshɔn to yu bɔdi ɔl di tɛm we yu de du di tritmɛnt.
Dɛn kin chɛk yu dɔktɔ ɔltɛm
Yu dɔktɔ go de chɛk yu ɔltɛm ɛn arenj fɔ mek dɛn du yu blɔd tɛst. Mek shɔ se yu atɛnd dɛn tin ya ɔltɛm. Dɛn tɛst ya go ɛp yu dɔktɔ fɔ si aw di mɛrɛsin de afɛkt yu bɔdi ɛn aw yu liva de wok.
Tek kia ɔf yu yay.
Sɔm pipul dɛm wae de tek dis mɛrɛsin kin gɛt chenj na dɛn yay. Fɔ ɛgzampul, yu nɔ kin si fayn, yu kin si halo dɛn rawnd layt dɛn, ɛn yu kin fil se layt dɛn kin apia ɛn dɔnawe wantɛm wantɛm. If yu si ɛni wan pan dɛn chenj ya na yu yay, tɛl yu dɔktɔ wantɛm wantɛm.
Protɛkt yusɛf frɔm infɛkshɔn
Kansa drɔgs lɛk Crizotinib kin wik smɔl yu bɔdi in imyun sistɛm, we min se yu kin sik mɔ, mɔ di infɛkshɔn.
- If yu gɛt sɔm sayn dɛn lɛk fiva, kol, trot we de at, ɔ kɔf , nɔ fɔ tek mɛrɛsin fɔ yusɛf. Kɔl yu dɔktɔ wantɛm wantɛm.
- Nɔ go na say dɛn we pipul dɛn kin ful-ɔp ɛn usay pipul dɛn we gɛt sik de as mɔ as yu ebul.
- Wash yu an bɔku tɛm wit sop.
- We yu gɛt fiva, nɔ tek mɛrɛsin lɛk Aspirin, Ibuprofen, ɔ Panadol (Acetaminophen) we yu nɔ go to yu dɔktɔ fɔ ridyus am. Dɛn tin ya kin stɔp di fiva ɛn mek di bɔdi nɔ no se i gɛt infekshɔn.
Protɛkt yusɛf frɔm di san.
Yu skin kin fil bad fɔ di san we yu de tek dis mɛrɛsin. Dat mek,
- Nɔ go na do na di san as yu ebul.
- If yu go na do, wɛr klos we kɔba yu bɔdi fayn ɛn wɛr hat.
- Aks yu dɔktɔ ɛn yuz gud tin fɔ protɛkt yusɛf frɔm di san.
Bεlε, bεlε εn fεtiliti
Dis pɔynt rili impɔtant.
- We yu gɛt bɛlɛ: Yu fɔ avɔyd fɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin ɔ fɔ 45 dez afta yu dɔn stɔp di tritmɛnt. Dis mɛrɛsin kin mek di pikin we nɔ bɔn yet gɛt siriɔs prɔblɛm wit in bɛlɛ. Yu fɔ gɛt bɛlɛ tɛst bifo yu bigin tritmɛnt fɔ mek shɔ se yu nɔ gɛt bɛlɛ.
- Fɔ man dɛm: If yu de tek Crizotinib ɛn yu patna kin bɔn pikin, mek shɔ se yu yuz kɔndɔm we yu de du mami ɛn dadi biznɛs we yu de du tritmɛnt ɛn fɔ 90 dez afta yu dɔn stɔp di tritmɛnt.
- Fɔ gi yu pikin in mama in bɛlɛ: Nɔ gi yu pikin in bɛlɛ we yu de trit am ɛn fɔ 45 dez afta yu dɔn stɔp di tritmɛnt.
- Di we aw pɔsin kin bɔn pikin:dis mεdisin kin afekt fεtiliti (abiliti fכ bכn pikin) pan uman εn man. If yu gɛt ɛnitin fɔ wɔri bɔt dis, tɔk to yu dɔktɔ bɔt am bifo yu bigin fɔ trit yu.
Sayd ɛfɛkt dɛn we kin apin bikɔs ɔf dis mɛrɛsin
Lɛk ɛni mɛrɛsin, Crizotinib kin mek yu gɛt sayd ɛfɛkt. Bɔt, nɔto ɔlman kin gɛt dɛn. Sɔm pan dɛn na smɔl smɔl tin dɛn. Bɔt sɔm tin dɛn de we yu fɔ no bɔt wantɛm wantɛm.
| Sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
|---|---|
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong ɔ trot. |
| Di chenj dɛn we de apin na di at rit | Fɔ fil lɛk se yu at de bit fast ɔ nɔ de bit ɔltɛm, yu ed de tɔn, yu de fɔdɔm, yu de fil pen na yu chɛst, ɛn yu nɔ go ebul fɔ blo. |
| Di at rit we de go dɔŋ | Diziz, fɔdɔm, kɔnfyushɔn, i nɔ kin izi fɔ blo, ɛn fil taya we nɔ kɔmɔn. |
| Di sayn dɛm we de sho se di liva dɔn pwɛl | Pen na di ɔp rayt say na di bɛlɛ, yu nɔ kin want fɔ it, yu nɔ kin fil fayn, yu kin gɛt layt kɔlɔ, yu kin gɛt dak yɔlɔ ɔ brawn urine, yu skin ɔ yu yay kin yɔlɔ, yu kin taya we nɔ kɔmɔn. |
| Prɔblɛm dɛn we gɛt fɔ du wit di lɔng | Dray kɔf we nɔ ɛksplen, i nɔ kin izi fɔ blo, i kin shɔt fɔ blo. |
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, kɔf, trot we de at, wund we nɔ de wɛl, pen we yu de pis. |
| Ɔda siriɔs sayn dɛn | Yu kin chenj di we aw yu de si, yu mɔt ɔ yu trot kin so, yu kin gɛt siriɔs ɔ we kin kɔntinyu fɔ dayarɛa, yu kin fil lɛk layt. |
| Sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu ɔ de mɔna am | |
| Kɔmɔn sayd ɛfɛkt dɛn |
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Mɛsej we dɛn kin kɛr go na os
- Crizotinib na wan tritmɛnt we dɛn kin yuz fɔ mɛn kansa. Yu fɔ tek am jɔs lɛk aw yu dɔktɔ tɛl yu.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek (inklud di mɛrɛsin dɛn we yu nɔ de bay). Nɔ tek dis mɛrɛsin wit grep jus.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt lɛk we yu de si chenj, we i nɔ izi fɔ blo, we yu at de bit, ɔ fiva , tɛl yu dɔktɔ wantɛm wantɛm.
- Nɔ stɔp fɔ tek di mɛrɛsin ɔ chenj di doz if yu dɔktɔ nɔ advays yu.
- Nɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin ɛn fɔ di tɛm we dɛn tɛl yu fɔ gɛt. Tɔk to yu dɔktɔ bɔt di we dɛn we sef fɔ kɔntrol di pikin.
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