Yu dɔktɔ dɔn tɛl yu se yu gɛt shuga, ɔr yu dɔn nia fɔ gɛt shuga (prediabetes)? We yu se dat, yu kin dɔn yɛri di wɔd "insulin resistance". Yu go de wɔnda wetin na dis nyu wɔd. Nɔ fred. Tide wi go tɔk bɔt dis ɛn de mɛrɛsin wae dɛn kin gi fɔ dis sik. Lɛ wi ɔndastand dɛn tin ya jɔs lɛk aw wi de tɔk to wi padi.
Wetin na Insulin Sɛnsitiviti?
Fɔ tɔk am simpul wan, insulin na wan rili impɔtant ɔmon we wan ɔgan na wi bɔdi we dɛn kɔl pankrias de mek. we di shuga (glucose) we de insay di it we wi de it go insay di bכdi, na di ki we de εp di shuga fכ go insay di bכdi in sεl dεm εn mek εnεji.
Imajin se di sɛl dɛn na yu bɔdi na domɔt dɛn, ɛn insulin na di ki we de opin dɛn domɔt dɛn de.
- Fɔ gɛt gud insulin sɛnsitiviti min se: We yu put dis ki (insulin) insay, di domɔt (sɛl) kin opin izi wan. Di shuga we de na di blɔd kin go insay di sɛl dɛn izi wan ɛn i kin chenj to ɛnaji.
- Insulin resistance min: I nɔ kin izi fɔ mek da ki de opin di domɔt. I tan lɛk se di domɔt dɔn stɔp. So bikɔs dɛn nɔ ebul fɔ opin di domɔt, di shuga we de na di blɔd kin go ɔp. Dɔn di pankrias kin bigin fɔ mek mɔ insulin, lɛk fɔ briŋ mɔ ki fɔ opin domɔt we stɔp. As tɛm de go, na dis kin mek pɔsin gɛt dayabitis (tayp 2 dayabitis).
So, wetin insulin sensitivity drugs de du na fɔ mek dɛn stik domɔt dɛn de izi fɔ opin. Dat min se, dɛn de ɛp insulin fɔ wok fayn fayn wan.
Wetin na di men mɛrɛsin fɔ dis?
Di bɛst we fɔ mek yu gɛt mɔ insulin na fɔ chenj di we aw yu de liv yu layf. Dis kin min fɔ du ɛksɛsayz ɔltɛm, fɔ it tin dɛn we gɛt fayn fayn tin dɛn fɔ it, ɛn fɔ kɔntrol yu wet. Bɔt yu dɔktɔ kin gi yu mɛrɛsin bak wit dɛn mɛrɛsin ya.
Tu men kayn mɛrɛsin dɛn de.
1. Biguanides - Di onli drog we de insay dis kategori na di Metformin we pipul sabi gud gud wan.
2. Thiazolidinediones (TZDs) - Dɛn kin gɛt mɛrɛsin bak na dis grup.
Naw lɛ wi luk ɛni wan pan dɛn kayn dɛn ya wan bay wan.
Metformin, we wi ɔl no
Metformin na di mɛrɛsin wae dɛn kin yuse pasmak fɔ tayp 2 dayabitis na di wɔl. If yu gɛt dayabitis, i go mɔs bi se yu de tek dis mɛrɛsin.
Aw mɛtfɔmin de wok?
Metformin de ɛp fɔ kɔntrol di blɔd shuga insay tu men we dɛn:
- I de ridyus di shuga we di liva de mek: Wi liva de mek shuga bak we di bɔdi nid am. Bikɔs mɛtfɔmin de kɔntrol dis prɔses, di shuga we nɔ nid we kin gɛda na di blɔd kin ridyus.
- I de mek di insulin sɛnsitiviti na di mɔsul dɛn go ɔp: Dis na di tin we impɔtant pas ɔl. di mכsul sεl dεm kin bigin fכ ansa fayn fayn wan to insulin. Dɔn di shuga we de na di blɔd kin go insay di mɔsul dɛn izi wan ɛn i kin chenj to ɛnaji.
Stɔdi dɔn sho se fɔ tek mɛtfɔmin kin ɛp fɔ delay fɔ bigin fɔ gɛt dayabitis pan pipul dɛm we de pan denja ɛn protɛkt frɔm tin dɛm lɛk at sik.
| Fɔ tɔk smɔl bɔt Metformin | |
|---|---|
| Di doz we dɛn fɔ yuz | Yu dɔktɔ go disayd di doz. Dɛn go ɔltɛm bigin wit smɔl doz ɛn smɔl smɔl dɛn go inkrisayz am. Dɛn kin tɛl yu fɔ tek am wan ɔ tu tɛm insay di de wit it. |
| Di Kɔmɔn Sayd Ɛfɛkt dɛn | Bɛlɛ kin at, nɔs, vɔmit, ɛn mɔ dayarɛa kin apin. Dɛn tin ya kin stɔp insay sɔm dez as di bɔdi de ajɔst to di mɛrɛsin. Dɛn kin ridyus dɛn tin ya bad bad wan if yu tek di mɛrɛsin wit it. |
| Tin dɛn we yu fɔ wach bɔt | Dis mɛrɛsin nɔ fayn if yu gɛt siriɔs kidni sik . כlso, wan kכndyushכn we rili rεs bכt denja we dεn kכl "laktik asidכsis" kin apin. If yu gɛt sɔm sayn dɛn lɛk we yu mɔsul dɛn de kramp, yu taya pasmak, yu de nɔs, ɛn yu de blo kwik kwik wan, go na ɔspitul in imejensi dipatmɛnt (ETU) wantɛm wantɛm. |
Nɔ lɛk ɔda mɛrɛsin dɛn fɔ gɛt dayabitis, mɛtfɔmin nɔ kin mek pɔsin gɛt mɔ wet. Sɔm pipul dɛn kin ivin lɔs sɔm wet.
Tiazolidindiɔn (TZD) dɛn .
Dis na di ɔda grup fɔ drɔgs. Dɛn tin ya kin mek di insulin sɛnsitiviti bak. Tu men kayn drɔgs de na dis grup: Pioglitazone ɛn Rosiglitazone .
Dɔktɔ dɛn kin tɛl yu fɔ yuz mɛtfɔmin fɔs. If i at fɔ kɔntrol wit am ɔ fɔ ɔda rizin, yu kin tink bɔt dis TZD klas fɔ mɛrɛsin.
I rili impɔtant: If yu dɔn gɛt ɔ yu dɔn gɛt kɔnjɛstiv at fayl, dɛn TZD mɛrɛsin ya nɔ fayn atɔl , bikɔs dɛn kin mek di sik wɔs.
| Tayp fɔ mɛrɛsin | Tin dɛn we yu fɔ no |
|---|---|
| Pioglitazɔn we dɛn kɔl Pioglitazone | Dis kin mek bak di insulin sɛnsitiviti go ɔp. Sɔm stɔdi dɛn dɔn sho se i kin afɛkt di liva, i kin mek pɔsin gɛt blad kansa, ɛn i kin mek in bon brok. |
| Rosiglitazɔn we dɛn kɔl Rosiglitazɔn | Dis kin wok bak di sem we lɛk di mɛrɛsin we wi dɔn tɔk bɔt. Pan ɔl we pipul dɛn bin de wɔri trade bɔt di risk fɔ gɛt at sik, leta stɔdi dɛn nɔ dɔn kɔnfirm dis. Bɔt i impɔtant fɔ no bɔt at sik we yu de yuz dɛn tu mɛrɛsin ya. |
| Kɔmɔn sayd ɛfɛkt dɛn we TZD dɛn kin gɛt | Di sayn dɛm kin bi we yu gɛt bɔku bɔku wet, swel bikɔs yu nɔ gɛt wata, yu chɛst kin pen, ɛn i nɔ kin izi fɔ blo. If yu gɛt ɛni wan pan dɛn sik ya, go to yu dɔktɔ wantɛm wantɛm. |
Aw yu kin pik di rayt mɛrɛsin fɔ yu?
Dis na kwɛstyɔn we rili impɔtant. Bɔt nɔto fɔ yu fɔ ansa, na fɔ yu dɔktɔ . Na bikɔs i kin tink bɔt bɔku tin dɛn we i de pik di rayt mɛrɛsin fɔ yu.
- Aw yu gɛt dayabitis?
- Yu gɛt ɛni ɔda mɛrɛsin (at sik, kidni sik, liva sik)?
- Wetin na yu ej ɛn di we aw yu de liv yu layf?
- Wetin na di sayd ɛfɛkt ɛn bɛnifit ɛn bad tin dɛn we di mɛrɛsin gɛt?
Na afta we i dɔn tink bɔt ɔl dɛn tin ya, na in i kin disayd di mɛrɛsin we fit ɛn we nɔ bad ɛn di doz fɔ yu.Nɔ ɛva yuz mɛrɛsin we yu padi de tek, ɔ mɛrɛsin we ɔda pɔsin tɛl yu fɔ du.
Mɛsej we dɛn kin kɛr go na os
- Insulin rεsistεns na we yu bכdi in sεl dεm nכ de rεspכnd fayn to insulin. Dis na di men tin we kin mek pɔsin gɛt tayp 2 dayabitis.
- Metformin ɛn TZD drɔgs na di men mɛrɛsin dɛm we de ɛp fɔ mek di insulin sɛnsitiviti go ɔp.
- Jɔs lɛk aw i impɔtant lɛk mɛrɛsin, ɛn sɔntɛm i impɔtant pas dat, fɔ it fayn ɛn fɔ du ɛksɛsayz ɔltɛm impɔtant fɔ mek yu gɛt mɔ insulin.
- Na yu dɔktɔ nɔmɔ go ebul fɔ gi yu mɛrɛsin. Tek di doz we i gi am, jɔs lɛk aw dɛn tɛl am, ɛn di rayt tɛm.
- Bifo yu bigin fɔ tek ɛni nyu mɛrɛsin, tɔk to yu dɔktɔ opin wan bɔt di bɛnifit dɛn we i go gɛt, di bad tin dɛn we i kin du, ɛn di bad tin dɛn we i kin du. Nɔ fred ɔ shem. Na yu rayt.
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