Yu dɔn ɛva wɔnda aw infɔmeshɔn kin travul go ɛn kam bak na wi bren? I tan lɛk se bɔku smɔl mɛsenja dɛn de wok togɛda fɔ du wan wɔndaful wok. Wi kin kɔl dɛn mɛsenja ya nyurotransmitta. Sɔmtɛm, bikɔs ɔf sɔm mɛdikal kɔndishɔn, dis mɛsej chenj kin gɛt smɔl kɔnfyus. Na da tɛm de sɔm mɛrɛsin dɛn kin kam ɛp wi. Tide wi go tɔk bɔt wan pan dɛn kayn mɛrɛsin ya, we dɛn kɔl dopamine antagonists.
Fɔ tɔk am simpul wan, wetin na dɛn dopamin antagonist ya?
Fɔ ɔndastand dis, wi nid fɔ no fɔs wetin na dopamin. Dopamin na wan rili impɔtant nyurotransmitta na wi bren. I kin ɛp fɔ kɔntrol bɔku tin dɛn, lɛk aw wi de tink, aw wi de fil, ɛn aw wi de muv.
naw imajin se wi bren sεl dεm gεt sכm sכm ‘lכk' dεm. Wi kin kɔl dɛn tin ya ‘rɛsɛptɔ’. di mεsenja dopamin lεk ‘ki’. we dis ki fit insay da lכk (rεsεptor), da sεl de de bi ‘aktiv’, we min se i de stat fכ du in wok.
Okay, so wetin wan drɔg we dɛn kɔl ‘dopamine antagonist’ de du? Dis drɔg tan lɛk ‘fak ki’ we yu kin put insay da lɔk de, bɔt yu nɔ ebul fɔ opin di lɔk. dat min se dis dכg de go insay di lכk `(rεsεptor)` we dopamin nid fכ sεt, εn i de `(blכk)` am.
Fɔ tɔk am simpul wan, imajin wan chia na pati we gɛt kad we rayt ‘Reserved’ pan am. Nɔbɔdi nɔ sidɔm de, bɔt yu nɔ go ebul sidɔm de, nɔto so? Na so dis drɔg de wok. i de kip di dopamin rεsεpכta inaktiv, we de mek rial dopamin nכ de kam insay εn aktibכt am.
Bikɔs i de kɔntrol di we aw sɔm bren sɛl dɛn de wok dis we, dis mɛrɛsin kin rili yus fɔ kɔntrol sɔm sik dɛn we pɔsin kin gɛt na in maynd ɛn ɔda sayn dɛn.
Us kɔndishɔn dɛn kin yuz dis mɛrɛsin fɔ?
Dɛn kin sheb di mɛrɛsin dɛn we de agens di dopamin to tu men kategori, bɔt sɔm tin dɛn de we sɔm mɛrɛsin dɛn kin wok na ɔl tu di kategori dɛn.
1. Antisaykotik drɔgs: Drug dɛm wae dɛn kin yuse fɔ trit saykosis ɛn ɔda tin dɛm wae gɛt fɔ du wit am.
2. Antiemetic drugs: Na mɛrɛsin dɛn we dɛn kin gi fɔ stɔp fɔ nɔs ɛn vɔmit.
Lɛ wi tek wan luk pan di men tin dɛm wae dɛn kin trit wit dɛn mɛrɛsin ya.
| Kategori fɔ drɔgs | Di kɔndishɔn dɛn we dɛn dɔn trit |
|---|---|
| Antisaykotiks |
|
| Antiɛmɛtiks |
|
Us kayn mɛrɛsin dɛn de pan dɛn kayn mɛrɛsin ya?
Bɔrku kayn drɔgs de wae kin fɔdɔm pan dɛn kayn mɛrɛsin ya. Antisaykotik drɔgs fɔ mɛntɛl sik kin jɔs sheb to tu "jɛnɛreshɔn dɛm." Dat min se, di ol drɔgs dɛm we dɛn bin fɛn fɔs (fɔs jɛnɛreshɔn) ɛn di nyu drɔgs dɛm we dɛn bin fɛn leta, wit smɔl sayd ɛfɛkt (sɛkɔn jɛnɛreshɔn).
Fɔs jɛnɛreshɔn (Typical) mɛrɛsin dɛn
Dis na sɔm pan di ol mɛrɛsin dɛn. Sɔm pan dɛn na:
- `Klɔrpromazin`
- `Halopɛridɔl (Haldol®)`
- `Flufenazin`
- `Pɛrfɛnazin`
- `Proklɔrpɛrazin`
Sɛkɔn jɛnɛreshɔn (Atypical) mɛrɛsin dɛn
Dɛn mɛrɛsin ya na nyu mɛrɛsin dɛn.
- `Olanzapin (Zyprexa®)`
- `Rispɛridɔn (Rispɛrdal®)`
- `Kwitiapin (Seroquel®)`
- `Aripiprazol (Abilify®)`
- `Klɔzapin (Klɔzaril®)`
Antiemetic mɛrɛsin fɔ nɔs ɛn vɔmit
Yu go dɔn si sɔm pan dɛn mɛrɛsin ya we dɛn rayt ɔp na di list fɔ di sik dɛn we pɔsin kin gɛt na in maynd. Di rizin na bikɔs dɛn kin du dɛn tu tin ya.
- `Mεtoklopramid (Reglan®)`
- `Proklɔrpɛrazin`
- `Olanzapin`
- `Halopɛridɔl`
- `Domperidone` (Dis mɛrɛsin nɔ de ɔlsay na Sri Lanka, ɛn yu kin gɛt am wit spɛshal pɔmishɔn nɔmɔ)
Impɔtant: Dis na jɔs sɔm ɛgzampul dɛn. Sɔntɛm yu dɔktɔ nɔ bin dɔn gi yu di mɛrɛsin we de na dis list. Nɔ ɛva yuz ɔda pɔsin in mɛrɛsin, stɔp fɔ tek am, ɔ chenj di doz if yu dɔktɔ nɔ advays yu.
Wetin na di bɛnifit dɛn we dɛn mɛrɛsin ya kin gi?
Dopamin antagonist na wan klas we rili yusful fɔ mɛrɛsin.
Fɔ mental sik:
Fɔ pɔrsin wae gɛt dis sik lɛk saykosis, dis mɛrɛsin kin sev in layf . E kin ridyus de risk fɔ mek pipul dɛm wae gɛt dɛn kayn sik ya fɔ du bad to dɛnsɛf ɔr ɔda pipul dɛn de trit dɛn bad. I kin gi dɛn mɔ chans fɔ liv nɔmal layf, wok, ɛn gladi wit dɛn famili.
Fɔ nɔs ɛn vɔmit:
Fɔ wi, fɔ vɔmit kin jɔs bi sɔntin we nɔ kin izi fɔ wi ɛn we kin dɔn afta sɔm tɛm. Bɔt tink bɔt pɔsin we gɛt kansa. Di nɔys ɛn vɔmit we dɛn kin gɛt we dɛn de tek di kemotɛrapi kin so bad dat i kin ivin mek dɛn day. Na tεm dεm lεk dis, we כda mεdikeshכn dεm nכ de wok, dεn mεdikeshכn dεm ya we de lεk dεn dopamin antagonist kin bכn dεn rεlif.
Ɛni sayd ɛfɛkt ɔ risk de?
Yɛs, lɛk ɛni ɔda mɛrɛsin, dɛn mɛrɛsin ya kin gɛt sayd ɛfɛkt. Bɔt nɔto ɔlman kin gɛt ɔl dɛn bad bad tin ya. I dipen pan bɔku tin, lɛk di mɛrɛsin we yu de tek, di mɛrɛsin we yu de tek, ɛn aw yu bɔdi tan. Di tin we impɔtant pas ɔl na fɔ nɔ fred dis ɛn tɔk to yu dɔktɔ opin wan.
| Posisibul sayd ɛfɛkt | Wan simpul ɛksplen |
|---|---|
| Sedeshɔn fɔ mek pɔsin fil fayn | Dis kin kɔmɔn fɔ di fɔs tɛm we yu de tek di mɛrɛsin. Dis go dכn as di bכdi de yus to di mεdikeshכn. |
| Dizayd dɛn we pɔsin kin gɛt we i de muv | - Akathisia: 1.Di rɛstlɛs fɔ nɔ ebul fɔ de na wan ples, di filin fɔ kɔntinyu fɔ muv rawnd. - Distonia: di mכsul dεm de tayt wan wan, i de twit (e.g., di nεk de jכk to wan sayd). - Tardive Dyskinesia: Na yu fes, yu mɔt, ɔ yu tɔng de muv we yu nɔ de kɔntrol we kin apin we yu yuz di mɛrɛsin fɔ lɔng tɛm. |
| Ɔtostatik Haypɔtɛnshɔn | Fɔ fil diziz ɔ layt ed we yu tinap wantɛm wantɛm frɔm sidɔm ɔ ledɔm. Dis kin kam bikɔs di blɔd prɛshɔn kin go dɔŋ wantɛm wantɛm. |
| Di Chenj dɛn we de na di Ɔmon dɛn | we di כmon we dεn kכl prolaktin inkrεs kin mek uman dεn stכp dεn mεnstral saykl εn fכ mek wata we lεk milk lik kכmכt na dεn brεst we dεn nכ de gi bεlε. |
| Nyurolɛptik Malignant Sindrom | Dis na tin we nɔ kin apin so ɔltɛm bɔt we kin mek pɔsin in layf de pan denja. If yu gɛt sayn dɛn lɛk ay fiva, mɔsul dɛn we stif, ɛn we yu nɔ de no natin wantɛm wantɛm, yu fɔ go na ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm. |
Yu dɔktɔ go tɛl yu mɔ bɔt dɛn sayd ɛfɛkt ya ɛn advays yu bɔt wetin yu go du fɔ mek yu nɔ gɛt bɔku prɔblɛm dɛn.
Sɔm ɔda kwɛstyɔn dɛn we yu go gɛt
Aw lɔng a nid fɔ tek dis mɛrɛsin?
I dipen pan di kɔndishɔn we dɛn de trit yu. Sɔm mɛrɛsin dɛn, lɛk mɛrɛsin dɛn we de mek pɔsin nɔ fil fayn, dɛn kin tek am nɔmɔ we dɛn nid am. Bɔt yu kin nid fɔ tek mɛrɛsin fɔ mental sik fɔ lɔng lɔng tɛm, ɔr ivin fɔ di res ɔf yu layf. Yu dɔktɔ go disayd ustɛm yu fɔ tek dɛn.
A kin wok ɔ drayv we a de tek dis mɛrɛsin?
Dis na kwɛstyɔn we rili impɔtant. Sɔm pan dɛn mɛrɛsin ya kin mek pɔsin slip bad bad wan ɔ taya . So, yu fɔ rili aks yu dɔktɔ if i sef fɔ drayv ɔ fɔ yuz mashin dɛn we yu de tek dɛn mɛrɛsin ya. I go gi yu di bɛst advays.
Dopamine antagonist na wan rili impɔtant klas fɔ mɛrɛsin we dɔn ɛp fɔ mek bɔku bɔku pipul dɛn layf bɛtɛ. Pan ɔl we dɛn kin gɛt bad bad tin dɛn we kin apin to dɛn, if dɛn mɛn dɛn fayn fayn wan ɔnda dɔktɔ in gayd, di bɛnifit dɛn kin pas dɛn fa fawe.
Mɛsej we dɛn kin kɛr go na os
- di mεdikeshכn dεm we dεn kכl dopamin antagonist dεm de blכk di rεsεpכta dεm na di bren we de gεt dopamin mεsej dεm.
- Dɛn kin yuse dɛn tin ya mɔ fɔ trit maynd sik lɛk saykosis ɛn siriɔs nɔs/vɔmit.
- Pan ɔl we dɛn mɛrɛsin ya rili woke, dɛn kin mek yu gɛt sayd ɛfɛkt lɛk fɔ slip ɛn prɔblɛm wit muvmɛnt.
- Nɔ ɛva bigin, stɔp, ɔ chenj di doz fɔ dis mɛrɛsin if yu dɔktɔ nɔ advays yu.
- If yu gɛt ɛnitin we nɔ kɔmɔn we yu de yuz di mɛrɛsin, nɔ fred fɔ tɛl yu dɔktɔ.
💬 Comments (0)
No kɔmɛnt nɔ de yet. Ad yu kɔmɛnt ya fɔ di fɔs tɛm.
Ad yu kɔmɛnt