Wi tink se wi nɔ go ebul fɔ chenj di tin dɛn we wi gɛt frɔm wi mama ɛn papa, nɔto so? Nɔto jɔs di yay kɔlɔ, di ia we tan lɛk, di we aw di skin tan, di ayt, bɔt ivin di risk fɔ gɛt sɔm sik dɛn... Wi no se ɔl dis kɔmɔt frɔm wi jin dɛn. So wi tink se dɛn jin ya tan lɛk sɔntin we dɛn kɔt na ston, we nɔ de chenj, ɛn we wi nɔ ebul fɔ kɔntrol. Bɔt... yu go sɔprayz if dɛn tɛl wi se wi kin chenj di "we" we dɛn jin ya de "wok" tru wi layf, di it we wi de it, ɛn di tin dɛn we wi de du? Epigenetics na di nyu ɛn wɔndaful sayɛns fild we de tɔk bɔt dis.
Fɔ tɔk am simpul wan, wetin na Epigenetics?
Dis kin tan lɛk smɔl sayɛns wɔd, bɔt di kɔnsɛpt rili simpul. Mek wi brok di wod `Epigenetics`. `Epi` na Grik fɔ "ɔp, rawnd, na do." `Jɛnɛtiks` na di sayɛns bɔt jin. εn `Epijenεtiks` na bכt di kכntrol we de "abov di jin dεm."
Tink bɔt am dis we. Yu jin dɛn tan lɛk di layt bɔl dɛn we de na yu os. Yu nɔ go ebul chenj wetin dɛn bɔl dɛn de ɔ usay dɛn de. Dem na somtin yu inherit. Bɔt yu gɛt di switch we de disayd if da bɔl de de ɔp ɔ ɔf. Sɔntɛm da bɔl de gɛt dima switch we de ɔn ɛn ɔf am.
semweso, `Epigenetics` na stori bכt wan sistεm we "kεmikכl swich" dεm we de kכntro if di jin dεm na wi bכdi de aktibכt (on/כf), כ if dεn aktiviti de rεdכks (dim), we nכ de chenj di layt bכl we dεn kכl jin.
Bɔku tin dɛn kin afɛkt dɛn kemikal ya we kin chenj, lɛk di we aw wi de liv wi layf, di it we wi de it, di say we wi de liv, ɛn di strɛs we wi kin gɛt. Sɔntɛnde, dɛn chenj ya kin fayn fɔ wi bɔdi, ɛn i kin protɛkt wi frɔm sik. Ɔda tɛm dɛn, dɛn kin ambɔg wi wɛlbɔdi.
Lɛ wi mɛmba wisɛf smɔl bɔt wetin na jin ɛn DNA?
Fɔ ɔndastand dis, lɛ wi fɔs luk smɔl pan di jin ɛn DNA.
Tink bɔt yu ɔl `DNA` sikyud as wan jayant rɛsipɛkt buk . Dis big buk gɛt ɔl di tin dɛn we ɔl di sɛl dɛn na yu bɔdi nid fɔ du in wok fayn fayn wan. Sεl dεm de lan wetin fכ du εn aw fכ du am bay we dεn ``rid`` dis ``DNA`` buk.
Bɔku trilyɔn sɛl dɛn de na wi bɔdi. Skin sɛl, at sɛl, bren sɛl, ɛn ɔda tin dɛn. εvri wan pan dεn sεl dεm ya gεt wan kכpi fכ di כl ``DNA'' rεsipi buk.
Bɔt, nɔto ɔl sɛl de rid dis wan ol buk. I nɔ nid fɔ du dat. Imajin, wan skin sɛl nɔ nid instrɔkshɔn frɔm wan at sɛl bɔt aw fɔ wok. Jɔs lɛk aw kek nɔ nid rɛsipɛkt fɔ sambol.
Jin na di wan wan rɛsipɛkt dɛn we de insay da big rɛsipɛkt buk de.Fɔ. Jin tan lɛk chapta na buk we de tɛl yu fɔ du wan patikyula wok. So, wan skin sεl de כnli rid di instrכkshכn (jin dεm) fכ di skin. Wan at sɛl de jɔs rid di instrɔkshɔn dɛn fɔ di at.
wetin `Epigenetics` de du na fכ disayd us rεsipi εvri sεl fכ rid εn uswan nכ fכ rid. I tan lɛk se yu put stika pan sɔm pej dɛn na rɛsipɛkt buk we se "Yuz dis naw" ɛn ɔda pej dɛn we se "Nɔ luk dis naw."
Wetin de afɛkt wi Epigenome?
di `epigenome` na di sistεm we dεn mek wit wi jin dεm εn di `kεmikכl switch dεm` we de kכntro aw dεn jin dεm de wok. di imכtant tin na dat dis `epigenome` nכ de statik. I kin chenj as tɛm de go, wit di tin dɛn we kin apin na wi layf.
Di tin dɛn we kin ambɔg dɛn chenj ya kin bigin bifo dɛn ivin bɔn wi. Si wetin dɛn de na di tebul we de dɔŋ ya.
| Influɛns factor | Simpul ɛksplen ɛn ɛgzampul dɛn |
|---|---|
| Di kɔndishɔn we mama gɛt we i gɛt bɛlɛ | Tin dεm lεk di mama in it, in maynd, εn di strεs we i de gεt kin afekt di jεnεtik aktiviti fכ di pikin in bεlε. |
| Di it we pikin dɛn kin it ɛn ɛkspiriɛns dɛn | Di it, di lɔv we mama ɛn papa gɛt, di protɛkshɔn, ɛn di chans fɔ lan we i smɔl ɛn we i smɔl de mek di epijɛnɛtik mak dɛn we de afɛkt di pikin in wɛlbɔdi tumara bambay. |
| Lɛ yu bɔdi kam dɔŋ | Di it dɛm we wi de it as big pipul, mɔ di it dɛm we dɛn dɔn prosɛs, drink dɛm we gɛt shuga, ɛn it dɛm we gɛt fat, kin gɛt bad impak, we di it dɛm we gɛt fayn fayn tin dɛm lɛk vɛjitebul, frut, ɛn ligɛm kin gɛt fayn impak. |
| Ɛksasayz | If yu de du tin wit yu bɔdi, dat kin mek di jin dɛn we de ɛp yu fɔ gɛt wɛlbɔdi ɛn i kin mek di jin dɛn we nɔ gɛt wɛlbɔdi nɔ tɔk natin. |
| Pɔyzin ɛn kemikal dɛn we de na di envayrɔmɛnt | If yu de na di motoka we de kɔmɔt na di motoka, di smok we de kɔmɔt na di sigrɛt, di kemikal dɛn lɛk (BPA) we de insay plastic, agrokemikɛl, ɛn ebi ebi mɛtal dɛn lɛk lid, dat kin ad mak dɛn we de ambɔg di jin dɛn. |
| Strɛs | If wi strɛs fɔ lɔng tɛm ɛn i kin mek wi bɔdi nɔ wok fayn ɛn i kin mek wi gɛt bɔku sik dɛn. |
| Alkol ɛn drɔgs | Alkol, tabak, ɛn ɔda drɔgs we wi de yuz kin pwɛl wi epigenome dairekt wan. |
Us sik dɛn kin gɛt fɔ du wit di epijɛnɛtiks?
Sayɛnsman dɛn stil de du risach bɔt dis, bɔt wetin dɛn no naw na dat di chenj dɛn we de apin na di epijɛnɛtiks gɛt sɔntin fɔ du wit bɔku sik dɛn.
- Kansa: Imajin, wi gɛt wan jin na wi bɔdi we de mek di kansa sɛl dɛn nɔ gro. Bɔt wetin kin apin if dɛn ‘ɔf’ dis jin, dat na fɔ mek dɛn nɔ tɔk natin, bikɔs ɔf bad layf? Dɛn kin gi di kansa sɛl dɛn di chans fɔ gro we dɛn nɔ ebul fɔ kɔntrol dɛn.
- Bren sik: Pruf de fɔ se di epigenetic chenj kin gɛt fɔ du wit sik dɛm wae gɛt fɔ du wit di ej lɛk Pakinsin sik ɛn Alzaima, ɛn sɔm kayn maynd sik ɛn intɛlektual disabiliti.
- Metabolism: Kɔndishɔn lɛk dayabitis ɛn fat kin afɛkt aw wi jin dɛn de wok. Di it we wi de it kin chenj di we aw dɛn jin ya de wok.
- di ol we dεn de ol: dεn ‘epigenetic’ mak dεm ya de afekt bak di ol we dεn de ol εn di sik dεm we de kam wit am.
- Imyun sistεm sik dεm: dεn ya de riliyt bak wit `autoimmune` sik dεm lεk asma εn at at, we min sik dεm we di bכdi in imyun sistεm de atak in כwn sεl dεm.
as risεch fכ dis de kכntinyu, sayɛnsman dεm de op fכ fכn nyu dכg dεm εn tritmεnt dεm we de tכk to dis ‘epigenome’.
So wi kin chenj wi epigenome fɔ di bɛtɛ?
Yɛs, i rili ebul fɔ du am!Na dat na di gud nyus. Pan ɔl we wi nɔ kin ebul fɔ chenj di jin dɛn we wi gɛt, wi kin afɛkt di we aw dɛn jin dɛn de wok fayn fayn wan. pan ɔl we no wan, difinitiv we nɔ de fɔ du dis, sayɛnsman dɛn biliv se wi kin mek fayn fayn ‘ɛpijɛnɛtik’ chenj dɛn bay we wi du dɛn tin ya:
Tin dɛn we yu go ebul fɔ du fɔ yusɛf
- It tin dɛn we gɛt fayn fayn tin dɛn fɔ it: Put bɔku tin dɛn we yu kin kuk na os, lɛk vɛjitebul, frut, grɛn, ɔl gren, ɛn fish. Ridyus di it dɛn we dɛn pak, we dɛn dɔn prosɛs, ɛn we gɛt bɔku shuga, we gɛt ɔyl.
- Put ɛksɛsayz insay yu ɛvride: Du sɔntin lɛk fɔ waka, rɔn, ɔ bayk fɔ at le 30 minit ɛvride. Bɔt if yu na nyu pɔsin fɔ du ɛksɛsayz, i impɔtant fɔ tɔk to yu dɔktɔ fɔs fɔ no us kayn ɛksesaiz we fayn fɔ yu.
- Limit alcohol and avoid smoking completely: Dis na tin dɛm we de damej wi `DNA` ɛn `epigenome` dairekt wan.
- Manej strɛs: Yu kin ridyus strɛs bay we yu de du tin dɛn lɛk fɔ tink gud wan, yoga, lisin to gud myuzik, du sɔntin we yu lɛk fɔ du, ɛn tɔk bɔt tin dɛn wit yu padi we yu abop pan.
If yu na mama ɔ papa, na sɔm tin dɛn we yu kin du fɔ yu pikin:
wi `epigenome` de chenj di mכst chenj dεm insay di fכs ia dεm na layf, so i imכtant fכ mama εn papa fכ no dis.
- Gi yu pikin di rayt it: Kɔnsul yu pikin dɛn bɔt dis.
- Gi yu pikin chans fɔ lan ɛn ple: Tɔk to yu pikin, rid buk, tich nyu wɔd dɛn, ɛn gi yu tɔys dɛn we go mek in bren gro.
- Mek ples we pipul dɛn lɛk ɛn sef: Mek ples na os usay di pikin go fil sef, lɛk, ɛn kia fɔ am.
- If yu de gɛt prɔblɛm dɛn lɛk we yu nɔ gɛt tin fɔ it, prɔblɛm wit os, ɔ fɛt-fɛt na yu os, duya go to dɔktɔ ɔ pɔsin we fit fɔ ɛp yu . Dɛn go gayd yu fɔ gɛt di sɔpɔt we yu ɛn yu pikin dɛn nid.
We wi yɛri di kɔnsɛpt fɔ `Epigenetics`, wi kin fil wan sɛns fɔ wɔnda, op, ɛn smɔl fred na wan say. We wi de tink bɔt wetin de apin insay wi bɔdi, tɛm kin de we wi kin fil lɛk se dɛn tin dɛn de nɔ ebul fɔ kɔntrol. Bɔt `Epigenetics` de tich wi se pan ɔl we tin dɛn de we wi nɔ ebul fɔ kɔntrol, wi gɛt sɔm pawa fɔ disayd bɔt wi wɛlbɔdi ɛn mek fayn chenj dɛn.
Mɛsej we dɛn kin kɛr go na os
- Pan ɔl we yu nɔ go ebul fɔ chenj di jin dɛn we yu gɛt frɔm yu mama ɛn papa, yu kin chenj aw dɛn de on/ɔf dɛn jin dɛn de.
- Tin dɛn lɛk aw yu de it, ɛksesaiz, strɛs, ɛn di say we yu de de afɛkt di we aw yu jin dɛn de wok dairekt wan. Dɛn kɔl dis epijɛnɛtiks.
- Sɔm pan dɛn chenj ya kin bɛnifit yu wɛlbɔdi, ɛn ɔda wan dɛn kin mek yu gɛt sik dɛn lɛk kansa ɛn dayabitis.
- If yu it tin dɛn we gɛt fayn fayn tin dɛn fɔ du, ɛksesaiz, nɔ smok ɛn drink rɔm, ɛn we yu nɔ gɛt strɛs, dat kin afɛkt yu jin dɛn fayn fayn wan.
- Di it ɛn kia we pikin dɛn kin gɛt, mɔ we dɛn bigin fɔ liv, kin afɛkt dɛn wɛlbɔdi tumara bambay fɔ lɔng tɛm.
- If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis, tɔk to yu famili dɔktɔ.
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