Yu an ɛn yu fut dɛn rɛd ɛn yu gɛt inflamɛns? I kin bi Hand-Foot Syndrome''!

If yu de tek kemotɛrapi fɔ kansa, ɔr yu sabi pɔrsin wae gɛt am, sɔmtɛm yu kin gɛt smɔl chenj, rɛd, swel, ɔr yu an ɛn yu fut kin pen. Fɔ sɔm pipul dɛn, dis kin mek dɛn at pwɛl smɔl. Nɔ wɔri, dis na tin we kin apin ɔltɛm. Tide wi go tɔk bɔt dis sik we dɛn kɔl ``Hand-Foot Syndrome - HFS'' , ɔ lɛk aw dɔktɔ dɛn kin kɔl am ``Palmar-Plantar Erythrodysesthesia'' .

Wetin na ``Hand-Foot Syndrome''? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, ``Hand-Foot Syndrome'' na wan skin riakshɔn we sɔm ``kimotɛrapi'' drɔgs kin mek. Speshal, yu an ɛn yu fut kin rɛd, swel, ɛn sɔntɛnde yu kin fil pen. Dis na wan kɔmɔn sayd ɛfɛkt we pɔsin kin gɛt we i de mɛn kansa. So i impɔtant fɔ no bɔt dis.

Us kayn kemotɛrapi mɛrɛsin kin mek pɔsin gɛt Hand-Foot Syndrome?

Nɔto ɔl di kemotɛrapi mɛrɛsin dɛn kin mek pɔsin gɛt dis sik. Bɔt sɔm mɛrɛsin dɛn de we dɛn dɔn si se kin mek i gɛt am mɔ. Dis "Hand-Foot Syndrome" bin fכs no we dεn gi di lukimiya pasεnshכn dεm hכy dכz fכ di drog "cytarabine."

Di kayn kemotɛrapi drɔgs we kin mek pɔsin gɛt HFS na:

• `(Kapesitabin)`
• `(Dɔsɛtaksɛl)`
• `(Pɛgylet liposomal dɔksorubisin - PLD)`
• `(5-fluoroyurasil)`

Ɔda kayn kemotɛrapi de we kin mek pɔsin gɛt HFS, pan ɔl we i nɔ kin bɔku:

• `(Bleomycin)`
• `(Sisplatin)`
• `(Sayklofosfamid)`
• `(Daunorubisin)`
• `(Dɔksifluridin)`
• `(Etoposide)`
• `(Fludarabin)`
• `(Jemsitabin)`
• `(Haydroksiyuria)`
• `(Idarubisin)`
• `(Ixabepilɔn)`
• `(Mɛtɔtrɛksɛt)`
• `(Mitotan)`
• `(Paklitaksɛl)`
• `(Tegafur)`
• `(Tiotepa)`
• `(Vinorɛlbin)`

If yu de tek ɛni wan pan dɛn mɛrɛsin ya, i fayn fɔ tek tɛm smɔl bɔt ``(HFS)''. Bɔt mɛmba se nɔto ɔlman we de tek dɛn mɛrɛsin ya go gɛt am.

Wetin na di risk factor dɛm fɔ mek yu gɛt ``Hand-Foot Syndrome''?

Di men tin na di amount of `(chemotherapy)` mɛrɛsin we dɛn gi yu ɛn di we aw dɛn de gi yu . Tink bɔt am, if di `(kemotherapy)` mɛrɛsin we dɛn de gi yu bɔku, ɔ if yu de tek di mɛrɛsin ɔltɛm, di chans fɔ gɛt dis sik kin bɔku. Dat min se if yu gɛt bɔku `(kimotɛrapi)` mɛrɛsin na yu bɔdi fɔ lɔng tɛm, di risk fɔ gɛt `(HFS)` bɔku.

Wetin na di sayn dɛm fɔ ``Hand-Foot Syndrome''? Aw wi kin no am?

Dɛn sayn ya kin bigin fɔ sho tu to tri wik afta dɛn dɔn bigin fɔ tek kimotɛrapi. Fɔs, yu kin fil lɛk se yu an ɛn yu fut dɛn kin swɛla smɔl. Leta, yu kin notis sɔm sayn dɛn lɛk:

• di an ɛn fut dɛn kin swel ɛn di kɔlɔ kin chenj: Pipul dɛn we gɛt fayn fayn skin, ɔ di wan dɛn we nɔ gɛt bɛtɛ melanin, kin notis se dɛn an ɛn dɛn fut dɔn rɛd (we tan lɛk aw dɛn kin bɔn wit di san). Pipul dɛn we gɛt brawn ɔ blak skin, ɔ di wan dɛn we gɛt bɔku melanin, kin notis se dɛn skin na dɛn an ɛn dɛn fut dɔn dak.
• swɛlin na di finga dɛn: Yu kin notis mɔ swɛlin, mɔ na say dɛn lɛk di pad dɛn na di finga dɛn.
• di skin kin tayt, i kin at, ɔ i kin fil pen we yu tɔch am: Di skin kin fil tayt ɔ i kin fil pen we yu tɔch am.
• Skin blista ɔ peel: Sɔntɛnde di skin kin blista ɛn peel.
• Pen we yu de pam ɔ yu fut na yu fut nak sɔntin: Fɔ ɛgzampul, yu kin fil pen we yu de waka ɔ tɔch sɔntin.

Dɛn sayn ya kin rili smɔl ɛn nɔr kin fil pen fɔ sɔm, ɔda wan kin gɛt siriɔs pen wae kin mek i nɔr kin izi fɔ du ɛvride.

Aw dɔktɔ dɛn kin no se i gɛt ``Hand-Foot Syndrome''?

If yu dɔktɔ ɔ nɔs si dɛn sayn ya we yu de tek kimotɛrapi, dɛn go sɔprayz se na Han-Fut Sindrom.

Bɔt if yu de tek wan kayn kansa mɛrɛsin bak we dɛn kɔl `(multikinase inhibitors)`, yu dɔktɔ go gɛt fɔ tink bɔt ɔda tin. Dat na wan kכndishכn we dεn kכl `(Hand-Foot Skin Reaction - HFSR)`. dis na sayd ifekt bak fכ `(multikinase inhibitors)`. `(HFSR)` de mek bak di skin chenj. Fɔ ɛgzampul, pen, tik, yɔlɔ skin kin kam na say dɛn lɛk di jɔyn dɛn, di fut dɛn, ɛn di an dɛn an.

Bikɔs ɔf dis, sɔntɛnde dɔktɔ kin tek di skin sɛl dɛn frɔm yu ɛn luk dɛn ɔnda maykroskɔp fɔ no if yu gɛt HFS ɔ HFSR.

I gɛt we fɔ no aw di ``Hand-Foot Syndrome'' siriɔs?

Yɛs, di Nashɔnal Kɛnsa Instityut dɔn mek wan we fɔ no aw dis sik bad bad wan, we dɛn kɔl gredin sistɛm . Yu dɔktɔ go disayd aw fɔ trit yu bay yu HFS gred.

• `(Grɛd 1) Han-Fut Sindrom`: I kin swel ɛn chenj in kɔlɔ (rɛd ɔ blak) na di an ɛn di fut, bɔt nɔ kin fil pen .
• `(Gred 2) Hand-Foot Syndrome`: Apat frɔm di sayn dɛm fɔ `(Gred 1)`, i kin gɛt blista, blɔd, ɛn pil pan di skin. Sɔntɛm pen kin de we kin mek i nɔ izi fɔ du tin dɛn we pɔsin kin du ɛvride .
• `(Grɛd 3) Han-Fut Sindrom`: Di sayn dɛm kin tranga pas di wan dɛm wae de na `(Gred 2)`. Di pen kin so bad dat ivin nɔmal wok dɛn nɔ kin ebul fɔ du . I kin tranga fɔ drɛs, shawa, ɔ go tɔylɛt.

Wetin na di tritmɛnt dɛm fɔ `(Hand-Foot Syndrome)`?

Naw lɛ wi si wetin dis kin du. If yu sik bad bad wan, min se dɛn de afɛkt yu layf sote yu nɔr ebul fɔ liv nɔrmal wan, yu dɔktɔ dɛn kin disayd fɔ stɔp di kemotɛrapi fɔ sɔm tɛm, ridyus di doz, ɔ chenj yu to ɔda mɛrɛsin.

Bɔt sɔntɛnde, fɔ mek dɛn chenj ya kin gɛt smɔl impak pan di sakrifays fɔ kansa tritmɛnt. If na so i bi, if yu sik nɔ tu tranga, yu dɔktɔ kin tɛl yu aw fɔ kɔntrol di bad tin dɛn we kin apin to yu.

Wetin wi kin du fɔ kɔntrol di sayn dɛn we wi kin gɛt?

Bɔrku pipul kin ebul fɔ kɔntrol di sayn dɛm wae de sho se yu gɛt Han-Fut Sindrom bay wae dɛn de mek sɔm simpul chenj na dɛn layf. Yu kin gɛt fridɔm bay we yu du dɛn tin ya:

• Yuz kɔtikosterɔyd krim: Dɔktɔ kin gi yu dis kayn krim fɔ mek yu nɔ swel ɛn nɔ gɛt inflamɛns.
• Put mɔstizayza - ɛmoliɛnt: Fɔ stɔp yu skin fɔ dray ɛn kip am fayn fayn wan, i impɔtant fɔ yuz mɔstizayza. Dɛn kin kɔl dɛn tin ya bak ɛmoliɛnt. Put dɛn bɔku tɛm insay di de.
• Yuz mɛrɛsin wae de mek yu fil pen: Yu kin tek pils wae yu kin it ɔr mɛrɛsin wae yu kin yuse fɔ yu pen, lɛk aw yu dɔktɔ tɛl yu.
• Protɛkt yu skin frɔm ɔt: Fɔ ɛgzampul, nɔ mek yu nɔ de na di san, yu fɔ was yu fut wit ɔt, ɛn sok yu fut dɛn na ɔt tub.
• Put ays pak ɔ kol klos: Fɔ mek blɔd nɔ go na yu an ɛn fut, put ays pak ɔ klin klos we yu dɔn sok insay kol wata na yu an ɛn yu anklɛ fɔ lɛk 15-20 minit. Bɔt nɔ put di ays dairekt pan yu skin, rap am wit klos.
• Kip yu an ɛn yu leg dɛn ɔp: We yu sidɔm na chia, kip yu leg dɛn ɔp, ɛn we yu de slip, put pilo ɔnda yu leg dɛn. Na di sem tin kin apin to yu an dɛn.
• Masaj yu skin saful wan: Ilɛksɛf yu de put loshan ɔ yu de drɛy yu skin wit tawɛl, nɔ rɔb yu skin tumɔs, pat am jisnɔ.
• Wear layt, lɔs sɔks ɛn sus: Wear sɔks we nɔ tayt, we dɛn mek wit tin lɛk kɔtɔn. Na di sem tin kin apin to sus, ɛn bɔku tɛm, sɔntin we layt lɛk sandal na in kin bɛtɛ.

Di tin we impɔtant pas ɔl na fɔ mek yu nɔ gɛt bɔku frikshɔn bitwin yu an ɛn yu fut.

Nɔ du dɛn tin ya, at least fɔ sɔm tɛm:

• Jɔg: Na bikɔs yu fut dɛn de na grɔn ɔltɛm.
• Di wok we dɛn kin du we dɛn de ol di ikwipmɛnt tayt:
• Hol di naif fayn fayn wan we yu de kɔt vɛjitebul.
• Yuz tul dɛn lɛk ɔs ɛn spayd we yu de wok na di gadin.
• Yuz wɛpɔn we yu de du os ripɛnt (e.g. fɔ ol hama we yu de drayv nel).
• Fɔ es di wet dɛn.

Wetin na di bɛst loshan fɔ `(Hand-Foot Syndrome)`?

Wan loshan we nɔ gɛt sɛnt, we nɔ gɛt rɔmPik. Alkol kin mek di skin dray mɔ, ɛn dis kin mek di sik dɛn wɔs. Sɔm stɔdi dɛn dɔn sho se if yu put krim we gɛt 10% yuria tri tɛm insay di de, dat kin ɛp fɔ mek di skin nɔ gɛt bɛtɛ trɛnk ɛn mek i wet. Bɔt i bɛtɛ fɔ go to dɔktɔ bifo yu yuz ɛni loshan.

Aw kwik a go wɛl afta a dɔn stɔp di tritmɛnt?

Dis kin difrɛn frɔm wan pɔsin to ɔda pɔsin. Bɔt dɛn sik ya kin stɔp smɔl smɔl insay tu to fayv wiks afta dɛn dɔn stɔp fɔ tek di kemotɛrapi. I kin tek sɔm dez mɔ fɔ mek i wɛl ɔl.

Yu tink se we dɛn de fɔ mek yu nɔ gɛt di sik we dɛn kɔl Hand-Foot Syndrome?

Pan ɔl we dɛn nɔ go ebul fɔ stɔp am ɔl, tin dɛn de we yu kin du fɔ ridyus di prɔblɛm ɛn fɔ mek di sik nɔ wɔs if i apin.

• If yu gɛt ɛni prɔblɛm wit yu skin (e.g. dray skin, krak krak skin), i fayn fɔ mek yu gɛt tritmɛnt bifo yu bigin fɔ tek kimotɛrapi.
• Bɔrku pan di we dɛm fɔ mɛn di sik dɛm wae wi bin dɔn tɔk bɔt fɔs kin ɛp bak fɔ mek di `(HFS)` nɔ bigin.
• Fɔ ɛgzampul, dɔktɔ kin tɛl yu fɔ yuz mɔstizayza frɔm di de we yu bigin fɔ tek kemotɛrapi.
• Tin dɛn we yu kin du bifo tɛm na fɔ protɛkt yu skin frɔm wam ɛn fɔ avɔyd tin dɛn we de put prɛshɔn ɛn frikshɔn we nɔ nid na yu an ɛn yu fut.

Wetin pɔrsin wae gɛt ``Hand-Foot Syndrome'' kin gɛt?

Infakt, nɔto ɔlman kin afɛkt dis ``Hand-Foot Syndrome`` di sem we. Ivin if dɛn tek di sem ``(kemotherapy)`` drɔg, di we aw wan pɔsin de fil kin rili difrɛn frɔm di we aw ɔda pɔsin de fil. Fɔ sɔm pipul dɛn, i kin jɔs bi smɔl prɔblɛm, bɔt fɔ ɔda pipul dɛn, i kin so bad dat dɛn kin gɛt fɔ chenj di tritmɛnt we dɛn kin gi dɛn kansa.

Di bɛst pat na dat, bɔku tɛm dɛn sik ya kin go wans dɛn dɔn dɔn di kemotɛrapi . If yu tek kia ɔf yu skin fayn fayn wan, yu kin bak fɔ mek yu nɔ gɛt prɔblɛm dɛn we go de fɔ lɔng tɛm lɛk fɔ gɛt skata.

Yu tink se Hand-Foot Syndrome kin mek ɔda prɔblɛm dɛn?

Wan tin na dat, sɔm pipul dɛn kin lɔs dɛn finga prɛnt fɔ sɔm tɛm. Dis kin mek yu at pwɛl smɔl sɔntɛnde. Fɔ ɛgzampul, we yu nid finga prɛnt we yu de go ɔda kɔntri, lɛk we yu de aplay fɔ visa. Bɔt nɔ wɔri, yu finga prɛnt go gro bak insay sɔm mɔnt afta di tritmɛnt dɔn.

Ustɛm a fɔ go to dɔktɔ?

I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɛni sik we yu gɛt we yu de tek kimotɛrapi, ilɛksɛf i smɔl. Speshali, mek shɔ se yu tɛl yu dɔktɔ if:

• If di sayn dɛm de bɔku smɔl smɔl.
• If di skin krak, di skin de kɔmɔt ɛn blɔd de kɔmɔt.
• If yu sayn dɛm de mek i nɔr izi fɔ du yu tin dɛm wae yu de du ɛvride.

Sɔntɛm lɛk dis, we yu tɛl di dɔktɔ , i kin gi yu di tritmɛnt we yu nid, ɔ mek chenj to di kemotɛrapi.

Us kwɛstyɔn dɛn a fɔ aks di dɔktɔ?

I go rili ɛp yu fɔ aks yu dɔktɔ ɔ nɔs kwɛstyɔn dɛn lɛk dɛn wan ya:

• Us sayd ɛfɛkt dɛn a kin ɛkspɛkt we a de tek kemotɛrapi?
• Us sayd ɛfɛkt dɛn a fɔ mek yu no bɔt?
• Us sayd ɛfɛkt dɛn a fɔ go to dɔktɔ ɔ go na ɔspitul fɔ?
• Tin dɛn de we a kin du fɔ mek a nɔ gɛt sɔm pan di bad tin dɛn we kin apin to mi?
• Ɛni spɛshal prɔdak de (lɛk loshan, krim) we yu kin rɛkɔmɛnd fɔ mek yu nɔ gɛt ɔ kɔntrol dis ``Hand-Foot Syndrome''?

Fɔ dɔn, wetin fɔ mɛmba (Take-Home Message) .

So, `(kemotherapy)` na wan rili impɔtant, layf-sev tritmɛnt fɔ kansa. Bɔt wi nid fɔ ɔndastand bak se dɛn bad bad tin ya kin apin. `(Hand-Foot Syndrome)` na wan kכmכn kכndyushכn bak, bכt bכku tεm dεn kin mεnεj.

If yu gɛt dɛn sik ya , nɔ panik ɔ panik . Di tin we impɔtant pas ɔl na fɔ tɔk opin wan bɔt dis wit yu wɛlbɔdi tim. Dɛn go ɛp yu fɔ kɔntrol yu sik ɛn mek chenj to yu tritmɛnt plan if nid de. Nɔto yu wan de, ɛn yu gɛt wɛlbɔdi tim we gɛt dɔktɔ dɛn, nɔs dɛn, ɛn ɔda pipul dɛn we sabi du dɛn wok fɔ ɛp yu pan dis waka. So, luk fɔ dɛn sɔpɔt if yu gɛt ɛnitin we de mɔna yu.

` Han-Fut Sindrom, HFS, kemotɛrapi, sayd ifɛkt, skin riakshɔn, palma-plantar ɛrithrodysesthesia, kansa tritmɛnt, kansa tritmɛnt, sayd ifɛkt, skin sik, palma inflameshɔn, palma inflameshɔn