Yu dɔn ɛva yɛri bɔt dɔktɔ gi yu ɔ sɔmbɔdi na yu famili ‘blɔd tina’ na ɔspitul? Di mɛrɛsin we dɛn kin gi yu kin bi ɛparin. Bɔku pipul dɛn kin kɔl am bak ‘blɔd thinner’. Bɔt dis nem kin mek pipul dɛn nɔ no di tru smɔl. I nɔ de rili ‘tin’ di blɔd lɛk wata. So wetin na am? I de mek di blɔd we de mek pɔsin denja nɔ kam insay wi bɔdi, ɔ i de mek di blɔd we dɔn de nɔ big. So tide, lɛ wi tɔk bɔt heparin, we impɔtant to bɔku pipul dɛn, insay wan simpul ɛn ɔndastandin we.
Wetin rili na Ɛparin?
Fɔ tɔk am simpul wan, ɛparin na wan tin we de mek pɔsin nɔ gɛt blɔd . Dat min se na drɔg we de mek blɔd nɔ klot. I nɔ de brok ɛn sɔlv wan blɔd we dɔn ɔlrɛdi fɔm, bɔt i kin ɛp di bɔdi fɔ sɔlv am bay we i de mek i nɔ big.
Yu go de wɔnda wetin mek dɛn nɔ de gi dis as pil. Di rizin na bikɔs wi intestinal nɔ kin ebul fɔ tek dis mɛrɛsin we dɛn kɔl heparin. So, if wi tek am as pil, i nɔ go gɛt ɛni yus. Na dat mek dɛn kin gi di mɛrɛsin we dɛn kɔl ɛprin ɔltɛm tu we dɛn:
1. Tru wan salin sכlushכn we dεn gi insay wan vein (IV Infusion): Dis de wok kwik kwik wan biכs di mεdisin de go dεrekt insay di bכdi.
2. As injɛkshɔn ɔnda di skin (Subcutaneous Injection): We dɛn gi am dis we, i kin tek lɛk wan ɔ tu awa fɔ mek di mɛrɛsin go insay di bɔdi.
Aw heparin de wok insay wi bɔdi?
Fɔ ɔndastand dis, lɛ wi tek wan smɔl ɛgzampul. Imajin se we blɔd klɔt na wi bɔdi na kɔmpleks tin, lɛk fɔ mek sɔntin na faktri. dis kin mek bכku difrεn wokman dεm (difrεn kεmikכl dεm εn protin dεm na wi bכdi) fכ wok tכgeda wan.
Tu pan di men wokman dɛm na dis faktri na ‘Thrombin’ ɛn ‘Factor Xa’ . Dɛn tu ya kin du sɔm pan di las ɛn impɔtant tin dɛn we kin mek di blɔd klɔt.
Heparin de akt lɛk smat supavaysa we de kam insay ɛn put di wɛpɔn dɛn we dɛn tu ki wokman dɛn ya gɛt na sayd. dat min se, hεparin de go insay εn deaktiv כl tu di ‘thrombin’ εn ‘factor Xa’. Dɔn dɛn nɔ ebul fɔ du dɛn wok. Afta sɔm tɛm, di wan ol faktri kin stɔp fɔ wok, ɛn nyu blɔd dɛn kin stɔp fɔ fɔm kpatakpata. Yu ɔndastand? I rili simpul, nɔto so?
Us kɔndishɔn dɛn dɔktɔ dɛn kin yuz ɛparin fɔ?
Heparin na wan rili impɔtant drɔg we kin sev pipul dɛn layf. So, dɛn kin yuz am fɔ trit ɛn fɔ mek dɛn nɔ gɛt difrɛn kayn mɛrɛsin. Lɛ wi luk di men kes dɛn.
| Kɔndishɔn/Okashɔn | Wan simpul ɛksplen |
|---|---|
| Venɔs Tromboɛmbolizm (VTE) . | di fכmeshכn fכ wan blכd kכlכt na wan vein na di bכdi. Tu men kayn dis de (DVT ɛn PE). |
| Blɔd we de klɔt na di dip vein (Dip Vein Thrombosis - DVT) . | Blɔd we de klɔt, bɔku tɛm na dip vein na di leg ɔ an. Dis risk kin pasmak afta dɛn dɔn du big ɔpreshɔn ɔr we yu fɔ de na wan ples fɔ lɔng tɛm. |
| Pulmonari Ɛmbolizm (PE) . | bכdi we de fכm na ples lεk DVT de brok εn i de lod insay wan vein na di lכng. Dis na imejensi ɛn denja kɔndishɔn. |
| At Atak we pɔsin kin gɛt | Fɔ mek i nɔ mek ɔda blɔd klɔt insay at atak we blɔd klɔt na wan vein we de gi blɔd to di at. |
| Strok | Insay kes dɛm we gɛt strok we blɔd klɔt na wan blɔd vesel na di bren. |
| Big Big Ɔpreshɔn dɛn | Ɛspɛshali afta dɛn dɔn du ɔpreshɔn lɛk fɔ chenj in hip ɔ in ni, di pɔsin kin gɛt ay risk fɔ gɛt blɔd klot bikɔs i nɔ kin muv. Fɔ mek i nɔ apin. |
| Atrial Fibrilɛshɔn (Afib) . | fכ ridyus di risk fכ blכd kכlכt fכ fכm na di at bikoz fכ di at bit we nכ de bit, we kin travul go na di bren εn mek yu strכk. |
| Kidni dayalaysis | Fɔ mek blɔd nɔ klɔt na di dayalaysis mashin we de klin di blɔd fɔ di wan dɛn we gɛt kidni we nɔ de wok fayn. |
apat frכm dat, kes dεm de we dεn kin yuz εparin if di mama de pan big risk fכ blכd kכlכt we i bεlε, biכs i nכ de du di pikin in bεlε.
Wetin kin apin we dɛn gi dɛn ɛparin? Aw dɛn kin wach am?
Dɔktɔ dɛn nɔ jɔs de gi yu heparin. Dis na mɛrɛsin we dɛn kin gi gud gud wan ɛn we dɛn kin wach ɔltɛm.
Bifo yu bigin fɔ trit yu wit ɛparin, yu dɔktɔ go mɔs tek yu blɔd ɛn du wan tɛst.
dis tεst dεn kכl am aPTT (aktivεt pat pan tromboplastin tεm) . I de mɛzhɔ aw lɔng i kin tek fɔ mek yu blɔd klot. Dɛn kin yuz di rizɔlt fɔ no di doz fɔ ɛp yu fɔ gi yu.
Ivin afta yu bigin fɔ trit yu heparin, dɛn go pul yu blɔd ɔltɛm (fɔ ɛgzampul, ɛvri 6 awa) ɛn dɛn go ripit dis aPTT tɛst. I de chɛk if di doz fɔ heparin we dɛn de gi yu na di rayt, i tu ay, ɔ i nɔ inof. Fɔ du dat, bɔku tɛm yu dɔktɔ go ajɔst di doz fɔ mek i de na di rayt lɛvul fɔ yu. Insay sɔm imejensi, we dɛn nid fɔ gɛt kwik rizɔlt, dɛn kin yuz ɔda tɛst we dɛn kɔl ACT (activated clotting time) .
Aw lɔng a fɔ tek ɛparin?
Dis dipen ɔl pan di rizin we mek dɛn de gi yu ɛprin. Fɔ ɛgzampul, afta dɛn dɔn du big ɔpreshɔn, dɛn kin gi am fɔ lɛk 7 dez te yu ebul fɔ grap ɛn waka. Fɔ wan sik lɛk at atak, dɛn kin gi am fɔ sɔm dez te dɛn kɔntrol di sik.
Bɔku tɛm, ɛparin na mɛrɛsin we dɛn kin gi na ɔspitul. Bifo yu go na os frɔm ɔspitul, yu dɔktɔ go pul yu di heparin we dɛn gi yu tru IV ɛn chenj yu to ɔda mɛrɛsin we de mek yu blɔd tan we yu kin tek as pil.
Di bɛnifit, risk, ɛn sayd ɛfɛkt dɛm fɔ heparin
Lɛk ɛni mɛrɛsin, ɛprin gɛt bɛnifit ɛn prɔblɛm dɛn.
Di men bɛnifit dɛn we heparin gɛt
- Fast acting: I de wok wantɛm wantɛm, mɔ we dɛn gi am insay in bɛlɛ.
- Fɔ pul am kwik kwik wan: We dɛn stɔp di mɛrɛsin, di tin dɛn we i kin du kin dɔn kwik kwik wan na di bɔdi. Dis kin rili impɔtant pan tin dɛn lɛk bifo dɛn du di ɔpreshɔn.
- Rivεrsibiliti fכ di ifekt: If di hεparin dכz sכm kayn we inkrεs εn blɔd de kכmכt, wan antidote de we dεn kכ l protamin we kin rivεs in ifekt wantεm wantεm.
- Di ia dɛn we dɛn dɔn trɔst:Na wan mɛrɛsin we dɛn dɔn stɔdi gud gud wan ɛn we dɔktɔ dɛn ɔlsay na di wɔl dɔn de yuz am sef wan fɔ lɔng lɔng tɛm.
Risk ɛn sayd ɛfɛkt dɛn
Di men ɛn siriɔs risk na we pɔsin de blɔd pasmak . We heparin de na di bɔdi, ivin smɔl wund kin mek yu blɔd bɔku.
So, if yu gɛt ɛni kayn brus we nɔ kɔmɔn we yu de tek heparin tritmɛnt, blɔd we de kɔmɔt na yu gam we yu de brus yu tit, ɔ ɛni ɔda blɔd we nɔ kɔmɔn , tɛl yu dɔktɔ ɔ nɔs wantɛm wantɛm .
If yu de grap na bed we yu de na ɔspitul, aks pɔsin fɔ ɛp yu fɔ mek yu nɔ fɔdɔm. If yu fɔdɔm, yu go gɛt mɔ blɔd.
If dɛn gɛt wan rili ay doz, smɔl chans de fɔ mek di ɔgan dɛn we de insay lɛk di bren, di lɔng dɛn, ɛn di bɛlɛ blɔd fɔ dɛnsɛf. Bɔt dis risk rili smɔl bikɔs dɛn kin kɔntrol di doz bay we dɛn de du blɔd tɛst ɔltɛm na ɔspitul.
Wan ɔda impɔtant tin! Ɔda mɛrɛsin dɛm wae yu de tek kin intarakt wit heparin. So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin, vaytamɛn, ɔ ɛbul mɛrɛsin we yu de tek.
Ɔda bad tin dɛn we kin apin:
- Pen ɔ brus na di say we dɛn injekt.
- Di ia we de lɔs (dis na fɔ shɔt tɛm).
- Trombocytopenia (dεn kin kכnt di pletlεt dεm lכw). Dis na sɔntin bak we dɔktɔ dɛn kin wach bɔku tɛm wit blɔd tɛst.
Sayn dɛn we de wɔn pipul dɛn we nid fɔ go to dɔktɔ wantɛm wantɛm
If yu gɛt ɛni wan pan dɛn sayn ya we yu de tek ɛparin, i kin bi sayn fɔ se yu de blɔd bad bad wan. So , nɔ delay ɛn go to dɔktɔ wantɛm wantɛm ɔ go na di ɔspitul Imejɛnsi Dipatmɛnt (ETU) we de nia yu.
| Di sayn dɛn we de sho se pɔsin de wɔn di sik | |
|---|---|
| 🔴 I at fɔ blo, fɔ blo kwik kwik wan. | 🔴 Blɔd we nɔ kin stɔp (e.g. frɔm di nos). |
| 🔴 Brus, spat, ɔ rash we nɔ kɔmɔn na di skin. | 🔴 Wan say na di bɔdi wik ɔ nɔ de fil fayn wantɛm wantɛm. |
| 🔴 Kɔnfyushɔn wantɛm wantɛm, i nɔ izi fɔ waka. | 🔴 I nɔ izi fɔ si ɔ yɛri wantɛm wantɛm. |
| 🔴 Na bad bad ed pen. | 🔴 Chest pen ɔ at bit kwik kwik wan. |
| 🔴 Vomit lɛk kɔfi grɔn. | 🔴 Stɔl we blak, tarry, ɔ gɛt blɔd insay. |
| 🔴 Yurin de tɔn brawn ɔ rɛd. | |
If dɔktɔ na ɔspitul dɔn disayd fɔ gi yu eparin, nɔ fred. I min se i rili impɔtant fɔ mek blɔd nɔ klɔt dipen pan yu kɔndishɔn. Dɔktɔ dɛn go de wach yu ɔltɛm ɛn gi yu di doz we yu nid ɛn we sef. If yu gɛt ɛni kwɛstyɔn bɔt dis, nɔ fred fɔ aks yu dɔktɔ.
Mɛsej we dɛn kin kɛr go na os
- Heparin nɔto tin we de mek blɔd tan, bɔt na drɔg we de mek di blɔd klɔt we de mek pɔsin denja .
- Dɛn nɔ go ebul fɔ tek dis as pil. Dɛn kin jɔs gi am as injɛkshɔn ɔ tru wan salin sɔlvushɔn we dɛn kin gi insay wan vein .
- De big risk fɔ dis tritmɛnt na fɔ mek yu blɔd bɔku pas aw i fɔ bi , so tek tɛm wit aksidɛnt lɛk fɔdɔm.
- I impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek (inklud vaytamɛn ɛn Ayurveda mɛrɛsin dɛn).
- If yu notis sayn dɛn we de wɔn yu lɛk fɔ vɔmit we tan lɛk kɔfi grɔn, blak stɔl, ɔ blɔd we yu nɔ go ebul fɔ stɔp, go to dɔktɔ wantɛm wantɛm.
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