Yu kin gɛt prɔblɛm bak fɔ blo bikɔs ɔf asma ɔ alɛji? Dɔn lɛ wi lan bɔt dɛn Leukotriene Modifiers ya!

Sɔntɛnde, ivin smɔl dɔst, pɔlin, ɔ it kin mek yu nɔ ebul fɔ blo fayn, yu chɛst kin tayt, ɔ yu kin kɔf ɔltɛm. Sɔntɛm yu nos de rɔn , yu de snis, ɔ yu trot de skrach. Dɛn tin ya kin rili mek pɔsin vɛks, nɔto so? Bɔrku tɛm, dɛn sik ya kin kam bikɔs ɔf wan riakshɔn na wi bɔdi. Tide, wi go tɔk bɔt wan spɛshal kayn mɛrɛsin we kin ɛp fɔ kɔntrol di prɔblɛm dɛn we pɔsin kin gɛt we i de blo we kin kam bikɔs ɔf tin dɛn lɛk asma ɛn alɛji. Dɛn kɔl dɛn Lukotrien Modifiers .

Wetin na di lukotrienes? Wetin mek dɛn de mɔna wi?

Fɔ tɔk am simpul wan, lɛukotriɛn na kemikal dɛn we wi bɔdi kin mek. Dɛn nɔ jɔs de mek dɛn bay chans. Imajin, we yu gɛt alɛji to sɔntin, dat na we sɔntin kam insay yu bɔdi, fɔ ɛgzampul, dɔst, pɔlin, sɔm it dɛn, dɔn wi imyun sistɛm kin wok wantɛm wantɛm ɛn pul dɛn lukotriɛn ya.

Na we dɛn lukotrien ya kɔmɔt na in wi kin bigin fɔ gɛt prɔblɛm. di rεspiretכri sistεm in patikyular de afekt mכst. Lɛ wi si wetin kin apin:

• Kɔf: Kɔf we kin kɔntinyu fɔ kɔf, we kin mek pɔsin fil pen sɔntɛnde.
• di mכkus we de bכku: Fluid dεm lεk mכkus εn flegm de bigin fכ kכmכt na di chεst εn trot. Dis kin mek yu gɛt sawnd we yu de blo we yu de blo.
• di say dεm we di briz de swεla: di say dεm we wi de blo, di ples dεm we wi de blo, de bigin fכ swel frכm insay. Jɔs lɛk we wata paip swel frɔm insay, di ples fɔ di wata fɔ flɔ kin smɔl.
• di aywe mכsul spasm: di sכm sכm mכsul dεm we de rawnd di aywe dεm de tayt εn kכntrakt, we de mek di aywe dεm ivin sכm.
• Chɛst tayt: I kin tan lɛk se sɔmbɔdi de swɛt yu chɛst, lɛk se dɛn de swɛt am.
• I nɔ izi fɔ blo ɔ swɛt: We dɛn jɔyn ɔl wetin wi dɔn tɔk bɔt, i kin rili at fɔ blo. Sɔm pipul dɛn kin gɛt swɛt.

Yu si, dɛn smɔl smɔl kemikal ya we dɛn kɔl leukotrienes de mek wi gɛt bɔku prɔblɛm.

So wetin na dɛn lukotrin modifya ya? Wetin dɛn mɛrɛsin ya kin ɛp wit?

Okay, naw wi no se bɔku tɛm na di leukotrienes kin mek dɛn gɛt dɛn prɔblɛm ya we dɛn kin gɛt we dɛn de blo. Lukotrien modifya na wan kayn mεdikeshכn we de kכntro εn modify di akshכn fכ dεn lukotrien dεm de. dεn kכl dεm bak lεukotriεn rεsεptכr antagonist כ luk כtriεn sεntez inhibito dεm.Ok. Pan ɔl we di nem kɔmplikt smɔl, dɛn mɛrɛsin ya kin du sɔntin we rili impɔtant.

Dɛn mɛrɛsin ya dɛn kin yuz mɔ fɔ:

• Alɛji, mɔ Alɛji Raynayt: Dis na wetin wi kin kɔl alɛji to dɔst mit ɔ pusi. Di sayn dɛm na we yu nos de rɔn, yu de sniz, yu nos de rɔtin, ɛn yu yay de it.
• Alɛji Asma: If di sayn dɛm fɔ asma wɔs bikɔs ɔf alɛji, dis mɛrɛsin kin ɛp.
• Asma we dɛn kin gɛt we dɛn de du ɛksɛsayz: Sɔm pipul dɛn kin gɛt mɔ asma sayn dɛn we dɛn de du ɛksɛsayz, rɔn, ɔ jomp. Dis mɛrɛsin kin fayn bak pan dɛn kayn tin ya.

Di impɔtant tin na dat dɛn nɔr de yuz dɛn mɛrɛsin ya fɔ ridyus kwik kwik wan fɔ ridyus alɛji ɔ asma atak we dɔn ɔlrɛdi apin. Dɛn kin yuz dɛn fɔ mek dɛn kayn tin ya nɔ apin ɔ fɔ mek dɛn nɔ gɛt bɔku sik . I tan lɛk ɔmbrela, if yu ol am ɔp bifo ren kam, yu nɔ go wet. Na so i bi.

Us kayn Leukotriene Modifiers de?

Bɔku kayn mɛrɛsin dɛn de we de insay dis kategori. We yu dɔktɔ gi yu wan, dɛn kin kɔl am wan pan dɛn nem ya:

• Montelukast - Yu kin dɔn yɛri bɔt dis ɔnda di brand nem `Singulair®`.
• Zafirlukast - Dis kam ɔnda di brand nem `Accolate®`.
• Zileuton - Dis de ɔnda di brand nem `Zyflo®`.

Dɛn kin yuz ɔl tri fɔ mɛn asma. Bɔt na Montelukast nɔmɔ dɛn gri fɔ trit alɛji raynaytis , dat na, alɛji na in nos.

Aw dɛn mɛrɛsin ya kin wok? I wɔndaful, nɔto so?

Dɛn mɛrɛsin ya kin wok tu we dɛn. I tan lɛk se tu we dɛn de fɔ sɔlv prɔblɛm.

1. Montelukast ɛn Zafirlukast de pan wan grup fɔ drɔgs we dɛn kɔl leukotriene receptor antagonists . Imajin se sכm sכm ‘lכk' dεm de na yu bכdi, εn we dεn kεmikכl dεm we dεn kכl lεukotriεn dεn kam fכ fit insay dis lכk lεk ‘ki’, dat difεlεns fכ brith de apin. wetin dis dכg de du na, bifo dis lεukotriεn ki fit insay da lכk de, i de blכk da lכk de bay we i de insay כda ‘dכmi’ ki. Dɔn dɛn lukotriɛn dɛn de nɔ kin ebul fɔ wok. Dat min se i de stɔp di ifɛkt we di leukotrienes gɛt.

2. Zileuton na difren likl. I de pan wan grup fɔ drɔgs we dɛn kɔl leukotriene synthesis inhibitors.dis na wetin i de du bay we i de mek dεn ‘trobul’ kεmikכl dεm we dεn kכl leukotrienes insay di bכdi, dat na fכ ridyus dεn prodakshכn. I tan lɛk se yu stɔp fɔ mek guds na faktri. afta dat di amount of leukotrienes na di bodi de dכn.

Yu ɔndastand? wan we, i nכ de alaw di lukotrin dεm fכ wok, εn na כda we, i de ridyus di prodyushכn fכ lukotriεn dεm.

Aw a go yuz dis mɛrɛsin? Wetin a fɔ tek tɛm wit?

Dɛn lukotrin modifya ya kin kam insay di fɔm fɔ tablɛt, we min se dɛn kin tek dɛn wit mɔt .

Di tin we impɔtant pas ɔl na fɔ tek dis mɛrɛsin ɛvride lɛk aw yu dɔktɔ tɛl yu . I impɔtant fɔ tek di mɛrɛsin di rayt tɛm, ilɛksɛf i nɔ izi fɔ yu fɔ blo da de de ɔ yu nɔ gɛt am. Bikɔs, lɛk aw wi bin dɔn tɔk, dɛn kin yuz dɛn tin ya fɔ mek i nɔ izi fɔ blo. Jɔs lɛk wan vaytamɛn we yu kin gɛt ɛvride, yu nid fɔ tek am ɛvride fɔ mek yu kɔntinyu fɔ gɛt di prɔtɛkshɔn we i de gi yu.

Yu dɔktɔ go gi yu sɔm patikyula tin dɛn bɔt dis mɛrɛsin:

• Doz: Dis min aw fɔ tek ɛn ɔmɔs tɛm insay di de.
• Ustɛm fɔ tek di mɛrɛsin: Na mɔnin, tu tɛm insay di de, ɔ na nɛt. Dis kin dipen pan ustɛm yu sik kin tranga pasmak.
• If yu fɔ tek am wit it ɔ yu nɔ it am: Sɔm mɛrɛsin dɛn fɔ tek bifo yu it, sɔm afta yu it. Aks fɔ am gud gud wan.

Nɔ ɛva tek mɔ ɔ smɔl pan dis mɛrɛsin pas aw yu dɔktɔ tɛl yu. If yu du dat, i go mek di mɛrɛsin nɔ wok fayn ɛn i go mek yu gɛt bad bad tin dɛn we yu nɔ want.

Wetin na di bɛnifit dɛn we yu kin gɛt we yu yuz Leukotriene Modifiers?

If yu yuz dɛn mɛrɛsin ya kɔrɛkt wan, yu kin gɛt bɔku fridɔm. Na di bɛnifit dɛn ya:

• I kin izi fɔ blo: Di chɛst kin tayt ɛn swɛt, ɛn yu kin ebul fɔ blo fri wan.
• Yu kin ɛksesaiz pan ɔl we i nɔ kin izi fɔ yu fɔ blo: If yu bin dɔn gɛt shɔt briz we yu de du ɛksɛsayz, dis mɛrɛsin go mek yu ebul fɔ kɔntrol di sik ɛn du ɛksɛsayz.
• I de ɛp fɔ mek di say dɛn we di briz de blo opin: Wi bin se di say dɛn we di briz de blo kin swel ɛn tayt, so i kin ridyus dɛn tin dɛn de.
• I de ridyus di mכkus na di chεst εn trot: di mכkus de rεdכks, we de mek i izi fכ brith.
• I kin ɛp fɔ mek yu nɔ gɛt prɔblɛm wit yu brith, lɛk we yu gɛt alɛji ɛn asma atak.
• Ridyus di nɔmba ɛn di kayn we aw di riakshɔn ɛn atak kin tranga.

Dis kin mek yu layf izi fɔ yu ɛvride.

Ɛni prɔblɛm de wit dɛn mɛrɛsin ya?

Lɛk ɛni mɛrɛsin, dɛn lukotrin modifya ya kin gɛt sɔm risk dɛn.

Liva damej we sɔm lukotrien modifya dɛn kin mekI pɔsibul. So, if yu dɔn gɛt liva sik, yu nɔ go ebul fɔ yuz dɛn mɛrɛsin ya. We yu de tek dis mɛrɛsin, yu dɔktɔ kin du blɔd tɛst bak fɔ chɛk if yu liva de wok fayn. Dis na fɔ yu sef.

Wetin na di bad tin dɛn we kin apin to pɔsin?

Lukotrien modifya dεm dεn kin jεnarali kכnsidr dεm sef. Bɔt sɔm pipul dɛn kin gɛt sayd ɛfɛkt. Nɔ wɔri, bɔku tɛm dɛn tin ya nɔ kin siriɔs.

Di sayd ɛfɛkt dɛn we dɛn kin si:

• Di sayn dɛm fɔ kol: kɔf, trot we de at, nos we de rɔn.
• Bɛlɛ we de at: Dayrɛa, bɛlɛ pen.
• Infekshɔn na di yes.
• Taya: I min se yu de fil taya.
• Di sayn dɛm we tan lɛk flu: fiva.
• Ed de at .
• At bɔn: I kin tan lɛk se yu de bɔn na yu chɛst.
• I de it ɔ rash.
• Di it nɔ de te.
• Nɔs: Fɔ fil lɛk fɔ vɔmit.

If yu gɛt kɔmɔn sayd ɛfɛkt lɛk dis, if i nɔ go dɔn insay sɔm dez, ɔ if yu si am se i nɔ izi fɔ bia, tɔk to yu dɔktɔ.

Bɔt sɔntɛnde, mɔ siriɔs sayd ɛfɛkt dɛn kin apin. If yu notis ɛni wan pan dɛn tin ya, yu fɔ go to dɔktɔ ɔ go na ɔspitul wantɛm wantɛm:

• Di chenj dɛn we de apin na di maynd wɛlbɔdi: Dis rili impɔtant. If yu gɛt pwɛl hat , yu kin tink bɔt fɔ kil yusɛf , ɔ yu kin vɛks wantɛm wantɛm , nɔ ignore am. Sɔm pipul dɛm wae de tek dis mɛrɛsin dɔn ripɔt se dɛn kin gɛt dɛn kayn tin ya na dɛn maynd. So, if yu ɔ sɔmbɔdi na yu famili notis big chenj na yu bihayvya ɔ mud we yu de tek dis mɛrɛsin, tɛl dɔktɔ wantɛm wantɛm.
• Blistering, peeling, ɔ siriɔs rash lɛk hayv.
• Hoarseness ɔ wan trot we de at.
• Di at we de blo.
• Yu kin fil lɛk se yu gɛt swɛt ɔ yu kin fil lɛk yu de swɛt na di an ɛn fut dɛn.
• Fɔ swel na yu fes, yu yay, yu mɔt, ɔ yu trot.
• I nɔ kin izi fɔ yu fɔ blo ɔ fɔ swɛla.
• Fɔ vɔmit.
• Yu skin ɔ yu yay we de yɔlɔ (Jaundice): Dis kin bi liva prɔblɛm.

If yu si sɔntin we siriɔs lɛk dis, i go fayn fɔ mek yu go to dɔktɔ ɛn yu nɔ go west yu tɛm.

Ɛni intarakshɔn de wit ɔda mɛrɛsin dɛn?

Yes, Leukotriene Modifiers kin intarakt wit ɔda mɛrɛsin dɛm we yu de tek. So, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, lɛk di mɛrɛsin dɛn we dɛn kin gi yu, di mɛrɛsin dɛn we yu kin bay we yu nɔ de it, di vaytamɛn dɛn, ɛn di mɛrɛsin dɛn we yu kin yuz fɔ mɛn yu.

Sɔm mɛrɛsin wae kin miks wit dɛn mɛrɛsin ya na:

• Sɔm mɛrɛsin fɔ kansa (e.g. `Alpelisib`, `dabrafenib`, `enzalutamide`).
• Sɔm kayn antibayɔtik (e.g. `Erythromycin`, `rifapentine`).
• Sɔm mɛrɛsin fɔ mɛntɛl sik (e.g. Loxapine - wan mɛrɛsin fɔ skizofrenia- lɛk kɔndishɔn).
• Mεdikeshכn dεm fכ sistik fibrosis (e.g. Lumacaftor).
• Sɔm antihistamin (e.g. Terfenadine - na mɛrɛsin we dɛn kin yuz fɔ protɛkt ɔ trit alɛji simptom dɛm).
• Blɔd tin dɛm (e.g. `Warfarin` - na mɛrɛsin we de ɛp fɔ mek blɔd nɔ klɔt, strok, ɛn at atak).

Dis list nɔ kɔmplit. So, mek shɔ se yu tɔk to yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek so dat i go tɛl yu di tritmɛnt we sef ɛn we fit yu.

Mɛsej we dɛn kin kɛr go na os

Okay, so a op se yu naw geht beta andastan boht di Leukotriene Modifiers we wi tok boht tide.

Fɔ tɔk smɔl, dɛn mɛrɛsin ya kin ɛp fɔ mek yu nɔ gɛt prɔblɛm wit yu briz we yu gɛt alɛji ɔ asma. Dɛn fɔ tek dɛn ɛvride, ilɛksɛf yu gɛt sɔm sayn dɛn ɔ yu nɔ gɛt di sik, ɛn lɛk aw yu dɔktɔ tɛl yu. Yu dɔktɔ na di bɛst pɔsin fɔ no if dis mɛrɛsin fayn fɔ yu ɛn if i go bɛnifit yu.

So, if yu gɛt dɛn kayn prɔblɛm ya we yu de blo, nɔ fred fɔ tɔk to dɔktɔ ɛn aks bɔt dɛn kayn tritmɛnt ya. Ɔlman fit fɔ ebul fɔ blo fri wan ɛn liv fayn layf!

` Lukotrien, leukotrien modifya, asma, alɛji, prɔblɛm fɔ blo, montelukast, zafirlukast, zileuton, sik dɛn we de mek pɔsin nɔ ebul fɔ blo