If yu dɔktɔ dɔn tɛl yu ɔ sɔmbɔdi na yu famili se yu gɛt Chronic Myelogenous Leukemia (CML), we na wan kayn blɔd kansa, yu go dɔn yɛri bɔt wan mɛrɛsin we dɛn kɔl Nilotinib. Dis na wan mɛrɛsin we rili impɔtant, we spɛshal. So tide, wi go tɔk simpul ɛn klia wan bɔt wetin yu nid fɔ no bɔt we yu de yuz dis mɛrɛsin, aw fɔ yuz am kɔrɛkt wan, ɛn us sayd ɛfɛkt fɔ ɛkspɛkt.
Wetin na Nilotinib?
Fɔ tɔk am simpul wan, Nilotinib na wan patikyula mɛrɛsin we de stɔp di kansa sɛl dɛn we de gro. Wi kin kɔl dɛn kayn mɛrɛsin ya "targeted therapy." Dat min se dis drɔg de go dairekt fɔ tɔch sɔm prɔtin dɛn we de na di kansa sɛl dɛn, i de stɔp dɛn fɔ wok, ɛn i de kɔntrol aw di kansa sɛl dɛn de sheb ɛn gro.
Dɛn kin yuz dis mɛrɛsin mɔ fɔ mɛn wan kayn lukimiya we dɛn kɔl Chronic Myelogenous Leukemia (CML) . Dɛn kin sɛl am bak ɔnda di nem Tasigna .
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Nilotinib na wan mɛrɛsin we rili pawaful. So, bifo yu bigin dis tritmɛnt, yu dɔktɔ go nid fɔ gɛt kɔmplit pikchɔ bɔt yu wɛlbɔdi. If yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ.
| Situeshɔn we kin apin to yu |
|---|
| Shuga |
| Kכndishכn dεm lεk hat sik, at ritm irεgulεri, כ Long QT sεndrכm. |
| Liva sik |
| If yu gɛt histri bɔt pankrias. |
| If yu gɛt smɔl potashɔm ɔ magnɛsiɔm na yu blɔd. |
| If yu gɛt prɔblɛm wit di blɔd we de go na yu leg. |
| If dɛn dɔn ɔpreshɔn di bɛlɛ ɔltogɛda (Total Gastrectomy). |
| If yu gɛt alɛji fɔ nilotinib, laktɔs, jelatin, ɔ ɛni ɔda mɛrɛsin ɔ it. |
| If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ. |
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
Fɔ mek yu gɛt di bɛst pan dis mɛrɛsin, i rili impɔtant fɔ yuz am kɔrɛkt wan.
- Tek ɛmti bɛlɛ: Dis na di tin we impɔtant pas ɔl. Yu fɔ tek di mɛrɛsin wan awa bifo ɔ tu awa afta yu it. If yu tek dis mɛrɛsin wit it, i kin chenj di we aw di bɔdi de tek am ɛn i kin mek yu gɛt bad bad sayd ɛfɛkt.
- Drink wit wan glas wata: Swɛla di kapsul ɔl wit wan glas wata.
- Nɔ brok, krɔs, ɔ chew di kapsul: Nɔ brok, krɔs, ɔ chew di kapsul.
- If yu gɛt prɔblɛm fɔ swɛla: Sɔm pipul dɛn kin gɛt prɔblɛm fɔ swɛla kapsul. If na so i bi, nɔ wɔri. Tek tɛm opin di kapsul, miks di paoda wit wan ti spɔnj apul, ɛn swɛla di miksɔp wantɛm wantɛm . Nɔ kip am fɔ yuz leta.
- Nɔ it grep: Nɔ drink grep jus ɔ it grep fɔ ɛni rizin. I kin chenj di we aw di mɛrɛsin de wok wit denja.
- Di tɛm fɔ tek am wit ɔda mɛrɛsin: If yu de tek mɛrɛsin fɔ gastritis, nɔ tek mɛrɛsin lɛk antasid (e.g., Digene) insay 2 awa bifo ɔ afta yu tek dis kapsul. Tek mɛrɛsin lɛk H2-blɔka (e.g., Famotidine) 10 awa bifo ɔ 2 awa afta yu tek dis mɛrɛsin. Aks yu dɔktɔ fɔ kɔnfirm dis.
- Tek am di rayt tɛm: Tray fɔ tek yu mɛrɛsin di sem tɛm ɛvride. Nɔ stɔp fɔ tek yu mɛrɛsin if yu dɔktɔ nɔ advays yu.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu mis wan doz, nɔ ɛva dubl pan di nɛks doz fɔ mek yu gɛt am. Dat kin denja. Fɔgɛt bɔt di doz we yu mis ɛn tek di doz nɔmɔ we yu dɔn tɛl yu na di nɛks tɛm we dɛn dɔn sɛtul.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu aksidɛntli tek mɔ pas di doz we dɛn tɛl yu fɔ tek, na imejensi. Wantɛm wantɛm, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital , ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Ɔda mɛrɛsin dɛm wae kin intarakt wit Nilotinib
Nilotinib na wan drɔg we gɛt ay pɔtnɛshɛl fɔ intarakshɔn wit ɔda mɛrɛsin dɛn. So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
| Nɔ tek Nilotinib wit dis mɛrɛsin. |
|---|
| Cisapride, Dronedarone, Pimozide, Thioridazine, Ziprasidone (mɛrɛsin dɛn we de afɛkt di at rit) |
| Flibanserin, Lomitapide, Saquinavir, ɛn ɔda pipul dɛn |
| Flukonazol, Posakonazol (antifungal) . |
| If yu de yuz dɛn tin ya, tɛl yu dɔktɔ. |
|---|
| Antivayral drɔgs fɔ HIV/AIDS |
| Antibayɔtik dɛn lɛk Klarithromycin ɛn Erythromycin |
| Mɛrɛsin fɔ ay blɔd prɛshɔn, at sik, ɛn maynd sik |
| Ɔda antifɔngal dɛn lɛk Ketoconazole, Itraconazole |
| Mɛrɛsin fɔ gɛt gastritis (Antacids, Cimetidine, Omeprazole) . |
| Blɔd tin dɛn lɛk Warfarin |
| Herbal prodak dɛm lɛk Sɛnt Jɔn Wɔt |
Nɔn pan dɛn list ya nɔ kɔmplit. So, i impɔtant fɔ mek yu sef fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn, vaytamɛn dɛn, ɛbul prɔdak dɛm, ɛn tradishɔnal mɛrɛsin dɛm we yu de tek.
Wetin na di sayd ɛfɛkt dɛn we pɔsin kin gɛt we i tek di mɛrɛsin?
Lɛk ɛni mɛrɛsin, Nilotinib kin mek yu gɛt sayd ɛfɛkt. Sɔm kin siriɔs, ɛn ɔda wan dɛn kin kɔmɔn. Di impɔtant tin na fɔ no bɔt dɛn tin ya ɛn tek akshɔn kwik if nid de.
| Sayd ɛfɛkt we pɔsin kin gɛt | Ficha dɛn fɔ ɛkspɛkt |
|---|---|
| Sayd ɛfɛkt dɛn we nid fɔ go to dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip ɔ tong. |
| Blɔd we de kɔmɔt | Blak ɔ blɔd stɔl, vɔmit we tan lɛk kɔfi grɔn, rɛd spat na di skin, blɔd we nɔ kɔmɔn frɔm di nos ɔ di gam. |
| Di chenj dɛn we de apin na di at rit | Chɛst pen, diziz, at bit fast ɔ i nɔ de bit ɔltɛm, fɔdɔm. |
| Liva injuri | Dak yɔlɔ ɔ brawn urine, yu yay ɔ skin de yɔlɔ, pen na di ɔp rayt pat na di bɛlɛ, yu nɔ go want fɔ it. |
| Pankriaytis we gɛt sik | Bɛlɛ pen (especially radiating to the back), pen we kin wɔs afta yu it, fiva, nɔs, vɔmit. |
| Fluid akyumyuleshכn na di bכdi (Edima) . | We yu gɛt bɔku bɔku wet wantɛm wantɛm, yu anklɛ dɛn, yu an ɛn fut dɛn kin swel, i nɔ kin izi fɔ blo. |
| Sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Disɔda dɛn we kɔmɔn | Ed pen, nɔs, vɔmit, dayarɛa, kɔnstipɛshɔn. |
Tek tɛm mɔ we yu gɛt bɛlɛ ɛn we yu de gi pikin milk
Dis na pɔynt we rili impɔtant.
- Nɔ ɛva gɛt bɛlɛ we yu de tek Nilotinib.
- Nɔ gɛt bɛlɛ fɔ at le 14 dez afta yu dɔn stɔp di mɛrɛsin.
- Nɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 14 dez afta yu dɔn stɔp.
Dis mɛrɛsin kin mek di pikin we nɔ bɔn yet gɛt siriɔs prɔblɛm, so tɔk to yu dɔktɔ bɔt dis opin wan.
Mɛsej we dɛn kin kɛr go na os
- Ɔltɛm tek Nilotinib pan ɛmti bɛlɛ, ɔ wan awa bifo ɔ tu awa afta yu it.
- Nɔ ɛva it grep ɔ drink in jus.
- Mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn ɛbul prɔdak dɛn we yu de tek.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt lɛk chɛst pen, i nɔ izi fɔ blo, ɔ blɔd we nɔ kɔmɔn, go to dɔktɔ wantɛm wantɛm.
- Nɔ gɛt bɛlɛ ɛn gi pikin in bɛlɛ ɔltogɛda we yu de tek di mɛrɛsin ɛn fɔ 14 dez afta yu dɔn stɔp.
- Nɔ skip yu klinik apɔntinmɛnt wit di dɔktɔ. Mek dɛn du yu blɔd tɛst lɛk aw dɛn dɔn plan fɔ du am.
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