Yu dɔn ɛva go to dɔktɔ wit fiva, kɔf, ɛn trot we de at ɛn dɛn gi yu mɛrɛsin lɛk "Amoxicillin"? Ɔ dɛn dɔn ɛva gi yu mɛrɛsin lɛk "Penicillin" fɔ wund? Bɔku pan wi dɔn yɛri bɔt dis mɛrɛsin, bɔt wi nɔ no bɛtɛ bɛtɛ wan wetin i bi, wetin i de du to di bɔdi, ɔ aw i de wok, nɔto so? Dis na rili wɔndaful mɛrɛsin we dɔn chenj di mɛrɛsin ɛn ɛp fɔ sev bɔku bɔku pipul dɛn layf. So tide, lɛ wi lan ɔltin bɔt penisilin insay wan rili simpul, tɔk-tɔk we.
Wetin na Pɛnisilin insay simpul wɔd dɛn?
Fɔ tɔk am simpul wan, penisilin na wan klas we dɛn kɔl antibayɔtik . Antibayɔtik na mɛrɛsin we de kil ɔ stɔp di bad bad bɔdi we de kam insay wi bɔdi. Tink bɔt di bad bad bɔdi we de kam insay wi bɔdi lɛk ɛnimi dɛn we de kam insay wan kɔntri. Dɔn penisilin tan lɛk sojaman we dɛn tren spɛshal wan we de pwɛl dɛn ɛnimi dɛn de.
dis penisilin de pan wan big famili fכ antibaytik we dεn kכl ``beta-lactams.`` dכkta dεn de yuz dis mεdisin as pil, likid, כ as ``intravenous'' (IV) injεkshכn.
Di tin we impɔtant pas ɔl na dat, penisilin de wok pan baktriyal infɛkshɔn nɔmɔ. I nɔ gɛt ɛni ifɛkt pan kɔmɔn kol ɛn flu, we na vayrɔs kin kam wit. So, nɔ ɛva yuz dɛn tin ya if dɔktɔ nɔ advays yu.
Us kayn sik dɔktɔ dɛn kin yuz penisilin fɔ?
Penisilin na wan antibayɔtik we gɛt bɔku spɛktrum we dɛn kin yuz fɔ trit bɔku bɔku sik dɛn. Yu dɔktɔ go pik di rayt kayn penisilin bay di kayn infekshɔn we yu gɛt. Na sɔm pan di tin dɛn we dɛn kin yuz mɔ.
| Mɛdikal kɔndishɔn | Wan simpul ɛksplen |
|---|---|
| Strep yu trot | Trot we de at we baktri dɛn kin mek. |
| Infεkshכn na yu yes (Otitis media) . | Infεkshכn na di yes kin bכku pan yכng pikin dεm. |
| Infεkshכn dεm na di urinary tract (UTI) . | Baktri infεkshכn dεm na di urinary tract. |
| Nyumonia | Baktri infεkshכn dεm we de afekt di lכng dεm. |
| Infεkshכn na di skin (Staph infεkshכn) . | Kכndishכn dεm lεk wund infεkshכn εn absεs fכmeshכn. |
| Meningitis we gɛt di sik | di membran dεm we de kכba di bren εn di spεnal kכd de swεla. |
| Infɛkshɔn na di tut | Baktri infεkshכn na di rut dεm na di tit כ di gכm. |
| Ɔda infɛkshɔn dɛn | Dɛn kin yuse am bak fɔ difrɛn sik dɛn lɛk sifilis, gɔno, ɛn Laym sik. |
Yu tink se kayn penisilin de?
Yɛs, difrɛn pipul dɛn de na di penisilin famili. Dɛn kin sheb dɛn to sɔm men grup dɛn bay aw dɛn mek dɛn ɛn di kayn baktri dɛm we dɛn kin kil.
- Natural penicillins: Dis na kayn tin wae kin apin natura, lɛk na tik. Sayɛnsman dɛn kin klin dɛn ɛn mek dɛn bi mɛrɛsin. εgzampl dεm fכ dis kayn na Pεnisilin G εn Pεnisilin V.
- Semi-synthetic penicillins: Na dɛn wan ya wi kin si bɔku tɛm. Sayɛnsman dɛn kin tek di natura penisilin ɛn chenj in strɔkchɔ smɔl na di lab fɔ mek i go bifo ɛn gɛt mɔ pawa. Drug dɛm lɛk Amoxicillin, Ampicillin, ɛn Dicloxacillin de insay dis kategori.
- Kɔmbayn mɛrɛsin dɛn:Sɔntɛnde, baktri dɛn kin rili kɔni. Dɛn kin fɛn dɛn yon we fɔ rɔnawe pan penisilin. Da tɛm de, fɔ mek di penisilin gɛt mɔ pawa, dɛn kin ad ɔda ɔgzilari mɛrɛsin. Fɔ ɛgzampul, yu go dɔn yɛri bɔt di drɔg ``(Augmentin)``. I gɛt ``(Amoxicillin)`` ɛn ɔda drɔg ``(clavulanic acid)`` we dɛn ad pan am.
Aw dis mɛrɛsin de wok insay di bɔdi?
Dis na wan prɔses we rili intrestin. Imajin se ɔl baktri gɛt strɔng sɛl wɔl fɔ protɛkt insɛf. Jɔs lɛk aw wi gɛt wɔl rawnd wi os. If dis wɔl nɔ de, baktri dɛn nɔ go ebul fɔ liv.
Wetin penisilin de du na dat i de go stret fɔ stɔp di baktri dɛm fɔ bil di wɔl . I tan lɛk se yu nɔ de mek di simen kam insay we yu de bil wɔl. We di wɔl nɔ bil fayn, i kin wik, i kin gɛt ol, ɛn afta sɔm tɛm i kin brok ɛn fɔdɔm. We di wɔl dɔn go, di baktri nɔ kin ebul fɔ liv, i kin day. Na so i bi.
So wetin ‘drug resistance’ min?
We sɔm bɔdi gɛt di sem kayn atak as tɛm de go, sɔm bɔdi kin rili kɔni. Dɛn kin lan nyu we fɔ rɔnawe pan dis penisilin atak. Fɔ ɛgzampul:
- dεn de mek εnzym dεm (lεk beta-laktamεz) we de pwεl penisilin.
- Ɔ dɛn kin chenj di kayn we aw dɛn difens wɔl tan, so dat penisilin nɔ go ebul fɔ go insay.
Wi kɔl dis antibayɔtik rɛsistɛns . Dis na di big big wɛlbɔdi prɔblɛm na di wɔl tide. MRSA (methicillin-resistant Staphylococcus aureus) na wan kayn baktri we nɔ de gri wit bɔku kayn penisilin.
Aw lɔng a fɔ tek penisilin? Wetin na di bad tin dɛn we kin apin to pɔsin?
Yu dɔktɔ go disayd aw lɔng yu nid fɔ tek penisilin. I go dipen pan di kayn infekshɔn we yu gɛt ɛn aw i siriɔs. Bɔrku tɛm i kin bi frɔm 5 to 7 dez to sɔm wik.
Di impɔtant tin we yu fɔ mɛmba ya na fɔ tek di mɛrɛsin fɔ di ful nɔmba fɔ di de dɛn we di dɔktɔ gi yu. Ivin if yu fil fayn afta tu ɔ tri dez, nɔ stɔp fɔ tek di mɛrɛsin. If yu stɔp, di strɔng baktri dɛm we lɛf na di bɔdi go yus to dis mɛrɛsin ɛn nɔ go wok di nɛks tɛm we yu gi am. Dis kin mek di chans fɔ mek yu nɔ gɛt antibayɔtik.
Kɔmɔn sayd ɛfɛkt dɛn
Lɛk ɔl di mɛrɛsin dɛn, penisilin kin mek smɔl smɔl sayd ɛfɛkt dɛn. Bɔt dɛn tin ya nɔ kin apin to bɔku pipul dɛn, ɛn if dɛn kin apin, bɔku tɛm dɛn nɔ kin siriɔs.
- Vɔmit
- Fɔ vɔmit
- Dayarɛa (blɛ kin at) .
- Sɔntɛnde, smɔl smɔl skin kin kɔmɔt.
- Lɔs fɔ apɛtit ɔ chenj pan sɛns fɔ teist/smɛl
- Ed de at
Bɔku tɛm, if yu tek di mɛrɛsin afta yu dɔn it, dat kin mek yu nɔ fil fayn na yu bɛlɛ lɛk fɔ nɔs.
Tin dɛn we yu fɔ tek tɛm wit we yu de tek penisilin
Pan ɔl we smɔl smɔl sayd ɛfɛkt dɛn de, sɔntɛnde, siriɔs risk kin de. I rili impɔtant fɔ no bɔt dis.
1. Alɛji fɔ Penisilin
Dis na di prɔblɛm we rili siriɔs. Bɔt fɔ tru, na smɔl pipul dɛn nɔmɔ gɛt alɛji fɔ penisilin. Bɔku pipul dɛn kin tink se dɛn gɛt alɛji, bɔt dɛn nɔ kin tink se dɛn nɔ gɛt alɛji. Bɔt fɔ pɔsin we rili gɛt alɛji, dis kin denja.
- Di sayn dɛm: di skin kin rɔsh, i kin it, i kin swel, i kin vɔmit, i kin gɛt diziz, ɛn if i rili siriɔs, i kin at fɔ blo.
- Wetin fɔ du: If yu gɛt prɔblɛm fɔ blo, yu de vɔmit, yu fes ɔ yu trot swel jɔs afta yu tek di mɛrɛsin, na imejensi. Go na di ɔspitul we de nia yu in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
2. C. diff infεkshכn
Dis na tin we kɔmplikt smɔl. Wi gɛt balans fɔ gud baktri ɛn bad baktri dɛm na wi gut. Sɔntɛnde, antibayɔtik lɛk penisilin kin kil sɔm pan di gud baktri dɛm wit di bad baktri dɛm. dis de mek di bad baktri dεm we dεn kכl Clostridium difficile (C. diff), fכ bכku we dεn nכ de chεk. Dis kin mek yu gɛt siriɔs dayarɛa we gɛt wata, yu bɛlɛ kin kramp bad bad wan, ɛn yu kin gɛt fiva .
| Ustɛm fɔ tɔk to yu dɔktɔ |
|---|
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| Ustɛm fɔ go na di ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm |
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Udat bin fɛn dis mirekul drɔg?
Dis na tin we rili sɔprayz ɛn aksidɛnt. Insay 1928, wan sayɛnsman we nem Alɛgzanda Flɛming bin go ɔlide we i nɔ bin klin sɔm Petri dish dɛn fayn fayn wan na in lɛbɔtri. We i kam bak, i si se di dish dɛn dɔn gro mold, nɔto baktri, bɔt day. I bin kam fɔ no se dis mold de pul sɔm kayn kemikal we de kil di bɔdi.
I bin rili at fɔ pul di tin we de kil baktri frɔm da mol de, klin am, ɛn mek am mɛrɛsin. Bɔt leta i bin wok fayn, ɛn pipul dɛn bin bigin fɔ yuz am bay 1946. Na da tin de we dɛn fɛn na di biginin fɔ di penisilin dɛn we wi de yuz tide.
Mɛsej we dɛn kin kɛr go na os
- Penisilin na antibayɔtik we dɛn kin gi fɔ baktriyal infɛkshɔn nɔmɔ . Dɛn nɔ de wok fɔ kol we vayrɔs kin kam wit.
- Nɔ ɛva yuz mɛrɛsin dɛn we tan lɛk penisilin fɔ yusɛf if dɔktɔ nɔ tɛl yu .
- Kɔmplit di ɔl di mɛrɛsin we di dɔktɔ gi yu. Nɔ stɔp af-af jɔs bikɔs yu fil fayn.
- If yu gɛt siriɔs alɛji lɛk fɔ blo ɛn yu fes de swel we yu de tek di mɛrɛsin, go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
- If yu de tek mɛrɛsin fɔ ɔda sik, ɔ if yu gɛt bɛlɛ ɔ yu de gi pikin in bɛlɛ, mek shɔ se yu tɛl yu dɔktɔ bifo yu tek penisilin.
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