Na nɔmal tin fɔ mek yu fred smɔl ɛn want fɔ no mɔ we yu dɔktɔ gi yu nyu, spɛshal mɛrɛsin fɔ yu ɔ pɔsin na yu famili. Ɛspɛshali if na kansa mɛrɛsin. So tide wi go tɔk bɔt wan pan dɛn kayn spɛshal mɛrɛsin ya, Pexidartinib. I kin kam ɔnda di brand nem Turalio. Lɛ wi tɔk bɔt dis mɛrɛsin, aw fɔ yuz am, wetin i kin du, ɛn wetin wi nid fɔ no bɔt, insay wan rili simpul we, lɛk se wi de tɔk to wi padi.
Fɔ tɔk am simpul wan, wetin na Pexidartinib?
Pexidartinib nɔto drɔg lɛk kemotɛrapi we wi kin no. Dis na drɔg we de insay di kategori we dɛn kɔl targeted therapy . Tink bɔt am, sɔm tɛm dɛn de, di mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn kansa ɔltɛm kin afɛkt gud sɛl dɛn bak. Bɔt dis tritmɛnt we dɛn kin tɔch na fɔ fɛn tin dɛn lɛk spɛshal prɔtin dɛn na di kansa sɛl dɛn ɛn fɔ stɔp dɛn fɔ gro. I tan lɛk se yu de yuz spɛshal ki fɔ opin spɛshal lɔk.
Dɛn kin yuz dis mɛrɛsin mɔ fɔ trit wan kansa sik we dɛn kɔl Tenosynovial Giant Cell Tumor (TGCT) . Dis na wan kayn tɔŋ we nɔ kin apin so ɔltɛm we kin apin na di jɔyn dɛn. So, wetin dis drɔg de du na fɔ stɔp dɛn kansa sɛl dɛn de fɔ gro ɛn kɔntrol di sik.
Tin dɛn we yu fɔ rili tɛl yu dɔktɔ bifo yu bigin fɔ tek di mɛrɛsin
Dis rili impɔtant. Bifo yu dɔktɔ disayd fɔ gi yu dis mɛrɛsin, i go nid fɔ no yu kɔmplit wɛlbɔdi istri. So, if yu gɛt ɛni wan pan dɛn tin ya, duya tɛl yu dɔktɔ ɛn nɔ ayd am.
- Liva sik: Dis mɛrɛsin kin afɛkt di liva, so yu fɔ rili tɛl yu dɔktɔ if yu dɔn ɔlrɛdi gɛt ɛni liva sik.
- Kidni sik: Di dɔktɔ fɔ no bak aw di kidni dɛn de wok.
- If yu de tray fɔ gɛt bɛlɛ ɔ yu gɛt bɛlɛ: I nɔ fayn atɔl fɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin. Wi go tɔk bɔt dis ditayli leta.
- If yu na mama we de gi pikin in mama in bɛlɛ: Dis nɔ fayn fɔ mama dɛn we de gi pikin in bɛlɛ, bikɔs di mɛrɛsin kin pas to di pikin tru di mama in milk.
- Ɔda Alɛji: Tɛl wi if yu gɛt ɛni alɛji, nɔto jɔs fɔ pexidartinib, bɔt fɔ ɛni ɔda mɛrɛsin, it, ɔ day.
Yu dɔktɔ tan lɛk yu bɛst padi. Nɔ ayd ɛnitin pan am. Yu sef go dipen pan di kɔrɛkt tin we di infɔmeshɔn we yu gi.
Aw ɛksaktɔli a fɔ yuz dis mɛrɛsin?
Fɔ mek yu gɛt di bɛst pan di mɛrɛsin, i impɔtant fɔ yuz am kɔrɛkt wan. Mɛmba dɛn instrɔkshɔn ya gud gud wan.
1. Oral Capsule: Dis na kapsul we yu fɔ tek wit wan glas wata.
2. Swɛla ɔl: Duya nɔ brok, krɔs, ɔ chew dis kapsul. Swɛla am ɔl.
3. Tek ɛmti bɛlɛ: Dis na di tin we impɔtant pas ɔl. Dɛn fɔ tek dis mɛrɛsin we dɛn nɔ it . Dat min se, yu fɔ tek am fɔ lɛk wan awa bifo yu it ɔ tu awa afta yu it . If yu tek am wit it, i kin afɛkt di we aw di mɛrɛsin de wok.
4. Nɔ tek wit grep jus: Nɔ drink grep ɔ grep jus we yu de tek dis mɛrɛsin. I kin rili afɛkt di we aw di mɛrɛsin de wok fayn.
5. Tek tɛm wit antisid: Nɔ tek antasid we dɛn kin yuz fɔ gastritis (e.g. Digene, Gelusil) insay tu awa afta yu tek dis mɛrɛsin.
6. Tek am di rayt tɛm: Tek yu mɛrɛsin di tɛm we dɛn tɛl yu fɔ tek am, lɛk aw yu dɔktɔ tɛl yu fɔ tek am. Nɔ tek pas di mɔni we dɛn tɛl yu fɔ tek.
7. Nɔ stɔp fɔ tek di mɛrɛsin we yu nɔ gɛt dɔktɔ advays: Nɔ stɔp fɔ tek di mɛrɛsin fɔ ɛni rizin if yu dɔktɔ nɔ advays yu.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu fɔgɛt fɔ tek wan doz, skip da doz de ɔltogɛda. Tek di nɛks doz di tɛm we yu kin tek am. Nɔ ɛva tek tu doz wan tɛm fɔ mek di doz we yu mis.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu kin aksidɛntli tek mɔ mɛrɛsin pas aw yu tink, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm. Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Ɔda tin dɛm wae kin intarakt wit dis mɛrɛsin (Interactions) .
Pexidartinib kin intarakt wit ɔda mɛrɛsin, vaytamɛn, ɔ ɛbul prɔdak dɛm we yu de tek. So, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn, ivin di vaytamɛn dɛn, we yu de tek. Na sɔm tin dɛn we wi fɔ tek tɛm mɔ bɔt.
| Di kayn drɔg/sɔbstans | Wetin mek yu fɔ bisin bɔt am? |
|---|---|
| Nɔ tek dɛn tin ya wit ɛnitin. | |
| Dasabuvir, Ombitasvir, Paritaprevir, Ritonavir (mɛrɛsin fɔ ɛpatitis C), Ranolazine (mɛrɛsin fɔ at sik) | Dɛn tin ya kin mek yu gɛt siriɔs sayd ɛfɛkt we yu kam togɛda wit Pexidartinib. |
| Tɔk bɔt dɛn tin ya wit yu dɔktɔ. | |
| Sɔm mɛrɛsin fɔ gastritis (e.g. Cimetidine, Famotidine, Omeprazole, Esomeprazole) . | dis kin ridyus di abzכpshכn fכ Pexidartinib insay di bכdi. |
| di we aw dεn de kכntrכl bכn wit כmon (pil, pat, injεkshכn) . | Pexidartinib kin ridyus di effektiv we fɔ kɔntrol bɔn pikin, so aks yu dɔktɔ bɔt aw fɔ yuz ɔda we fɔ kɔntrol bɔn pikin. |
| Grepfruit jus we dɛn kin mek | di pexidartinib lεvεl na di bכdi kin bi denja hכy. |
| St. John’s Wort (prɔdak we dɛn mek wit ɛbul) . | Dis de ridyus di effektiv we Pexidartinib de wok. |
| Ɔda antibayɔtik ɛn antifɔngal lɛk Rifampicin, Itraconazole | Dɛn tin ya kin afɛkt di lɛvɛl dɛn fɔ Pexidartinib. |
Sayd ɛfɛkt dɛn we kin apin we yu de tek di mɛrɛsin
Lɛk ɛni mɛrɛsin, dis mɛrɛsin kin mek pɔsin gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn. Bɔt, i impɔtant fɔ no bɔt dɛn tin ya.
| Di sayn dɛm wae yu fɔ ripɔt to yu dɔktɔ ɔr ɔspitul (ETU) kwik kwik wan | |
|---|---|
| Di sayn dɛm we de sho se di liva dɔn pwɛl | Dak yɔlɔ ɔ brawn urine, yu yay ɔ skin de yɔlɔ, pen na di ɔp rayt pat na di bɛlɛ, taya pasmak, nɔs, yu nɔ de want fɔ it, ɛn yu stɔl we gɛt layt kɔlɔ. |
| Siriɔs alɛji dɛn | Skin rash, it, swel na yu fes, lip ɔ tong, i nɔ izi fɔ blo. |
| Vɔmit ɔ fiva | Vɔmit ɔ fiva we nɔ go ebul fɔ stɔp. |
| If i kɔntinyu ɔ i de mɔna yu, tɛl yu dɔktɔ. | |
| Chenj in teist na di mɔt | Di chenj dɛn we de apin na di teist fɔ it. |
| Banbɛlɛ | I nɔ izi fɔ mek yu gɛt dɔti. |
| Swel ɔ swɛlin na di an ɛn fut dɛn | Tingling, pen, ɔ swel na di an, fut, ɔ finga. |
Speshal notis bɔt bɛlɛ ɛn fɔ bɔn pikin
Dis na pɔynt we rili impɔtant .
- Uman: Nɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin ɛn fɔ wan mɔnt afta yu dɔn stɔp di mɛrɛsin. Yuz wan we we pɔsin kin rili abop pan fɔ kɔntrol bɔn pikin insay dis tɛm.
- Man: If yu de tek dis mɛrɛsin, nɔ fɔ bɔn pikin we yu de tek di mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp.
Dis mɛrɛsin kin ambɔg di pikin we nɔ bɔn yet bad bad wan. I kin mek bak i nɔ ebul fɔ bɔn pikin fɔ sɔm tɛm ɔ fɔ ɔltɛm. If yu gɛt ɛnitin fɔ wɔri bɔt dis, tɔk to yu dɔktɔ bifo yu bigin fɔ trit yu.
Mɛsej we dɛn kin kɛr go na os
- Pexidartinib na spɛshal mɛrɛsin we de tɔch di kansa sɛl dɛn. I impɔtant fɔ tek am jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek am, i go fayn fɔ tek am we yu ɛmti bɛlɛ.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn ɛbul prɔdak dɛn we yu de tek. Nɔ drink grep jus.
- Go to dɔktɔ kwik kwik wan if yu gɛt sɔm sayn dɛn we de sho se yu liva dɔn pwɛl (di skin/yay we de yɔlɔ, yu urine dak) ɔ yu gɛt siriɔs alɛji.
- I rili impɔtant fɔ avɔyd fɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ di tɛm we dɛn dɔn tɛl yu fɔ tek. Dis kin apin to uman ɛn man.
- If yu gɛt ɛnitin fɔ wɔri bɔt, kwɛstyɔn, ɔ wɔri bɔt dis mɛrɛsin, duya tɔk bɔt am wit yu dɔktɔ. Dɛn kin rɛdi ɔltɛm fɔ ɛp yu.
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