Na nɔmal tin fɔ fil ebi ebi lod we yu yɛri se yu ɔ pɔsin we yu sabi gɛt kansa. Bɔt insay dis tɛm we mɛrɛsin sayɛns dɔn go bifo, bɔku tritmɛnt dɛn de we go ɛp yu fɔ bia wit am. Tide wi go tɔk bɔt wan pan dɛn kayn spɛshal drɔgs de. Dat na Regorafenib. Sɔntɛm yu dɔn yɛri bɔt dis nem.
Us kayn mɛrɛsin dis? (Wetin na Regorafenib?)
Fɔ tɔk am simpul wan, Regorafenib na mɛrɛsin we de atak di kansa sɛl dɛn ɛn ɛp fɔ stɔp dɛn fɔ gro. Tink bɔt kansa sɛl dɛn as bad sojaman dɛn na wi bɔdi. Wetin dis drɔg de du na fɔ stɔp dɛn bad sojaman dɛn de fɔ gɛt sɔm pan di tin dɛn we dɛn nid (especially proteins), wikɛd dɛn, ɛn slo dɛn fɔ skata.
Dɛn kin yuz dis mɛrɛsin mɔ fɔ mɛn dɛn kayn kansa ya:
- Kolorektal kansa (kansa na di big intestinal ɛn di rεktum) .
- Gastrointestinal stromal tumors (GIST), na wan kayn kansa we de apin na di dijestiv trakt
- Kansa na di liva
Yu kin fɛn dis mɛrɛsin ɔnda di brand nem `(Stivarga)`. Dis na wan mɛrɛsin we rili spɛshal, so yu fɔ yuz am jɔs lɛk aw yu dɔktɔ tɛl yu. I nɔ de wok fɔ ɔlman. Yu dɔktɔ go disayd fɔ gi yu dis mɛrɛsin afta i dɔn tek tɛm chɛk yu sik.
Wetin na de tin wae yu nid fɔ tɛl yu dɔktɔ bifo yu tek mɛrɛsin?
Bifo yu bigin fɔ tek Regorafenib, sɔm tin dɛn de we yu fɔ rili tɛl yu dɔktɔ ɔ nɔs. I impɔtant fɔ mek yu yon sef fɔ ɔnɛs bɔt dɛn tin ya.
- Blɔd prɔblɛm: Yu gɛt prɔblɛm wit yu blɔd we de klɔt, ɔ yu kin blɔd bɔku tɛm?
- At sik: Yu de sɔfa wit at sik? Yu dɔn gɛt at atak bifo?
- Ay blɔd prɛshɔn: Yu gɛt ay blɔd prɛshɔn? Yu de tek mɛrɛsin fɔ am?
- Liva sik: Ɛni liva sik de? Sɔntin lɛk janda dɔn kam?
- Di ɔpreshɔn we dɛn jɔs du: Yu dɔn du ɛni ɔpreshɔn i nɔ tu te yet?
- Alɛji: Yu gɛt alɛji, dat na, alɛji, to Regorafenib, to ɛni ɔda mɛrɛsin, it, day, ɔ tin dɛn we de mek yu nɔ pwɛl?
- If yu de tray fɔ gɛt bɛlɛ ɔ yu gɛt bɛlɛ: Yu de ɛkspɛkt pikin? Ɔ yu dɔn gɛt bɛlɛ? Dis rili impɔtant .
- If yu na mama we de gi pikin in bɛlɛ: Yu de gi yu pikin in bɛlɛ?
If yu tɛl wi dɛn tin ya kɔrɛkt wan, yu dɔktɔ kin disayd if dis mɛrɛsin fayn fɔ yu ɔ nɔ fayn fɔ yu. Ɔ, gi yu advays bɔt aw fɔ yuz am sef wan.
Aw a fɔ yuz dis mɛrɛsin? Wetin na di bɛst we?
Okay, so lɛ wi se di dɔktɔ gi yu dis mɛrɛsin. Dɔn, wan rayt we de fɔ tek am.
- Dis pil fɔ tek am bay mɔt . I bɛtɛ fɔ tek am wit wan glas wata.
- Fɔ fala di dɔktɔ in prɛskrishɔn lɛbl jɔs lɛk aw i rayt. Nɔ tek mɔ ɔ smɔl pas wetin di dɔktɔ tɛl yu fɔ tek.
- Dis mɛrɛsin fɔ tek wit it . Bɔku tɛm, i kin fayn fɔ tek am afta yu dɔn it tin we nɔ gɛt bɔku fat. Yu dɔktɔ go tɛl yu di rayt we fɔ du dis.
- Di tin we impɔtant pas ɔl na dat, nɔ drink grep jus we yu de tek dis mɛrɛsin. Dat min se fɔ drink bɔku bɔku grep jus nɔ fayn. I kin afɛkt di we aw di mɛrɛsin de wok fayn.
- Nɔ stɔp fɔ tek yu mɛrɛsin te yu dɔktɔ tɛl yu fɔ tek am. Ivin if yu fil fayn smɔl, i nɔ go fayn fɔ lɛ yu stɔp fɔ tek yu mɛrɛsin if yu dɔktɔ nɔ advays yu.
If yu gi pikin dɛn dis mɛrɛsin:
Yu fɔ tɔk to dɔktɔ we de mɛn pikin dɛn bɔt aw fɔ gi dis mɛrɛsin to yɔŋ pikin dɛn. I nid spɛshal kia.
Wetin yu go du if yu tek bɔku mɛrɛsin? (Ovadosage):
If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, go na di ɔspitul imejensi rum we de nia yu wantɛm wantɛm. Ɔ kɔl wan say usay dɛn de kɔntrol pɔyzin. Nɔ west tɛm.
Dis mɛrɛsin na fɔ yu nɔmɔ! Dis na mɛrɛsin wae de dɔktɔ dɔn gi yu fɔ yu sik ɛn yu bɔdi. So, nɔ ɛva sheb dis mɛrɛsin wit ɛni ɔda pɔsin.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
Sɔntɛnde, bikɔs yu bizi ɔ yu fɔgɛt, yu kin mis yu mɛrɛsin. If na so i bi:
- Tek di doz we yu mis as yu mɛmba.
- Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz (fɔ ɛgzampul, if yu nɛks doz fɔ kam insay sɔm awa), skip di doz we yu mis ɛn jɔs tek yu nɛks doz di tɛm we dɛn dɔn sɛtul.
- Nɔ ɛva tek dabl doz mɛrɛsin wan tɛm. If yu du dat, dat kin mek di bad tin dɛn we kin apin to yu bɔku.
Us ɔda tin dɛn kin miks wit dis mɛrɛsin? (Bi no bɔt di intarakshɔn dɛn)
Regorafenib na mɛrɛsin wae kin intarakt wit sɔm ɔda mɛrɛsin dɛm, ɛrb dɛm, ɔr sɔpɔtmɛnt dɛm, we kin mek yu gɛt sayd ɛfɛkt dɛm, lɛk fɔ mek i nɔ wok fayn ɔ fɔ mek i nɔ wok fayn.
Na sɔm tin dɛn we kin krash lɛk dat:
- `kabamazɛpin`
- `irinotekan`
- `itrakonazɔl`
- `kɛtokonazɔl`
- `fεnobarbital`
- `fɛnitoin`
- `posakonazɔl`
- `rifampin`
- `St. Jɔn in Wɔt` (Sɛnt Jɔn in Wɔt) .
- `telithromycin`
- `vorikonazɔl`
- `warfarin` ( wan tin we de mek blɔd tan) .
Dis list nɔto ɔltin de insay. Dat mek,Tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (prɛskrishɔn, ɔva-di-kɔnta, tradishɔnal mɛrɛsin, vaytamɛn, ɛvbɔdi), ɛn if yu de smok, drink rɔm, ɔ yuz ɔda drɔgs. Dis go ɛp am fɔ gi yu dis mɛrɛsin sef wan.
Wetin wi fɔ tek tɛm wit we wi de tek mɛrɛsin?
Sɔm tin dɛn de we yu fɔ tek tɛm wit smɔl we yu de yuz dis mɛrɛsin.
- Fɔ fil fayn: Yu kin fil fayn smɔl ɔr kin jɔs sik we yu de tek dis mɛrɛsin. Dis na nɔmal tin. Dis na bikɔs dɛn kayn tritmɛnt ya we de agens kansa nɔ kin afɛkt di kansa sɛl dɛn nɔmɔ bɔt i kin afɛkt sɔm sɛl dɛn we gɛt wɛlbɔdi na wi bɔdi. Bɔt if yu gɛt ɛni bad bad tin, tɛl yu dɔktɔ. Kɔntinyu fɔ trit yu te yu dɔktɔ tɛl yu fɔ stɔp.
- Blɔd wok: Dɛn go nid fɔ chɛk yu blɔd kɔnt ɔltɛm we yu de tek dis mɛrɛsin. Gɛt blɔd tɛst lɛk aw yu dɔktɔ tɛl yu.
- Bεlε εn we yu de gi pikin bεlε (i rili impɔtant!):
- If yu na uman, yu fɔ avɔyd fɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 2 mɔnt afta yu dɔn stɔp di mɛrɛsin. If yu de tray fɔ gɛt bɛlɛ ɔ yu tink se yu go gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm.
- If yu na man, nɔ tray fɔ bɔn pikin we yu de tek dis mɛrɛsin ɛn fɔ 2 mɔnt afta yu dɔn stɔp di mɛrɛsin. Dis mɛrɛsin kin mek di pikin we nɔ bɔn yet gɛt siriɔs sayd ɛfɛkt. Aks yu dɔktɔ ɔ fama fɔ no mɔ bɔt dis.
- Nɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 2 wik afta yu dɔn stɔp di mɛrɛsin.
- Bifo dɛn du di ɔpreshɔn: If yu go gɛt ɛni ɔpreshɔn, tɔk to yu dɔktɔ bɔt dis mɛrɛsin bifo i apin. Dis mɛrɛsin kin mek di wund dɛn we dɛn dɔn du ɔpreshɔn nɔ wɛl. Dɛn fɔ stɔp dis mɛrɛsin 2 wik bifo dɛn du di ɔpreshɔn. Afta di ɔpreshɔn, yu fɔ wet fɔ at le 2 wik bifo yu bigin di mɛrɛsin bak. Dɔn bak, di wund fɔ wɛl kpatakpata. If yu gɛt ɛni kwɛstyɔn bɔt dis, tɔk to yu dɔktɔ.
- Ɔda kansa risk: Smɔl risk kin de fɔ gɛt sɔm ɔda kayn kansa we yu de tek dis mɛrɛsin. Tɔk to yu dɔktɔ bɔt dis bak. Natin nɔ de fɔ wɔri bɔt, bɔt i fayn fɔ no.
Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?
Lɛk ɛni mɛrɛsin, Regorafenib kin mek sɔm sayd ɛfɛkt. Sɔm kin siriɔs ɛn yu fɔ tɛl yu dɔktɔ wantɛm wantɛm. Ɔda wan dɛn nɔ kin rili siriɔs, bɔt if dɛn kɔntinyu fɔ du am ɔ de mɔna yu, yu fɔ tɛl yu dɔktɔ .
Di sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm:
- Di sayn dɛn we pɔsin kin gɛt we i gɛt alɛji:Skin rash, it, ɛkzema, swel na yu fes, lip, ɛn tɔng.
- Stɔl we gɛt blɔd ɔ blak, we gɛt tar.
- I nɔ kin izi fɔ yu fɔ blo.
- Vishɔn chenj: yu nɔ de si fayn, yu nɔ de si fayn wantɛm wantɛm.
- Chɛst pen ɔ fil se yu chɛst tayt.
- Kɔnfyushɔn: Fɔ fil lɛk se yu maynd nɔ de pe atɛnshɔn igen.
- Diziz, we pɔsin kin fɔdɔm.
- Ay fiva.
- Stul dɛn we gɛt layt kɔlɔ.
- Nɔs, fɔ vɔmit.
- Rɛd ɔ dak brawn urine.
- Rɛd spat dɛn na di skin.
- Pen na di ɔpa rayt bɛlɛ (na di say we de rawnd di liva).
- Di sik dɛn we kin mek pɔsin sik.
- Di ed we de at bad bad wan.
- Han-Fut Skin Riakshɔn: Dis na sɔntin we yu kin si wit dis kayn mɛrɛsin.
- Vɔmit blɔd ɔ wan brawn tin we tan lɛk kɔfi grɔn.
- Bɛlɛ de pen.
- Blɔd we nɔ kɔmɔn frɔm di yay, gam, nos, ɔ brus ɛnisay na di bɔdi.
- Fɔ fil se yu taya pasmak, yu nɔ gɛt layf.
- Yu yay ɔ yu skin kin yɔlɔ (jaundice).
If yu si sɔntin lɛk dis, nɔ delay. Go to dɔktɔ wantɛm wantɛm.
Di sayd ɛfɛkt dɛm wae nɔr kin nid mɛrɛsin, bɔt yu fɔ ripɔt to yu dɔktɔ if dɛn kɔntinyu ɔr de mɔna yu:
- Dayarɛa (bɛlɛ we de at).
- Di vɔys we de ala lawd wan.
- Di it nɔ de te.
- Trot de at.
- Taya.
- We yu de lɔs yu wet.
Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu notis ɛnitin we nɔ kɔmɔn apat frɔm dɛn tin ya, tɛl yu dɔktɔ. Nɔ wɔri, yu dɔktɔ go ɛp yu.
Aw yu fɔ kip di mɛrɛsin?
I rili impɔtant bak fɔ kip yu mɛrɛsin fayn fayn wan.
- Kip dɛn usay pikin dɛn nɔ go ebul fɔ rich. Dɛn tin ya nɔto tɔys fɔ dɛn.
- Dɛn fɔ kip am na say we di ples kol bitwin 20 ɛn 25 digri sɛlshiɔs (68 ɛn 77 digri F. Dat min se yu nɔ fɔ kip am na say dɛn we wam pasmak ɔ we kol pasmak.
- Kip di mɛrɛsin bɔtul tayt tayt ɛn insay di ɔrijinal kɔntena we i kam insay.
- Trowe ɛni mɛrɛsin we yu nɔ yuz afta 7 wiks we yu opin di bɔtul. I izi if yu rayt di de na di bɔtul.
Mɛmba di tin we impɔtant pas ɔl! (Mɛsej we dɛn kin tek go na os)
So, wi don tok plenti abaut Regorafenib, no bi so? Mɛmba se dis atikul jɔs dɔn mek yu ɔndastand mɔ. Dis nɔto kɔmplit diskripshɔn.
- If yu gɛt ɛni kwɛstyɔn bɔt dis mɛrɛsin, ilɛksɛf na smɔl wan, aks yu dɔktɔ, nɔs, ɔ fama. Na dɛn go ebul fɔ ɛp yu di bɛst we.
- Fɔ fɛt kansa nɔ kin izi. Bɔt, gɛt maynd, fala wetin di dɔktɔ tɛl yu fɔ du, ɛn kɔntinyu fɔ du yu tritmɛnt.
- Nɔto yu wan de. Yu gɛt pipul dɛn we lɛk yu ɛn wan mɛdikal tim we go ɛp yu.
A op se dis infɔmeshɔn go ɛp yu. A de wish yu fɔ wɛl kwik kwik wan!
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Us kayn sik Regorafenib (Regorafenib / Stivarga) de trit?
Dis na sef ɛn advans ‘Targeted Cancer Therapy’ mɛrɛsin! Dɛn kin yuz dis mɛrɛsin as las tin afta ɔl di ɔda kɔvɛnshɔnal kemotɛrapi drɔgs dɛn nɔ wok, mɔ fɔ trit siriɔs kansa dɛn na di kɔlon (Kɔlɔrektal kansa), liva kansa (Hepatocellular carcinoma), ɛn spɛshal tɔŋ dɛn we de divɛlɔp na di bɛlɛ/intestinal wɔl (GIST).
💬 Aw dis dכg (Regorafenib) de kil/sכfכk kansa sεl dεm?
Dis na wɔndaful teknɔlɔji! Fɔ mek kansa gro, i nid fɔ mek nyu blɔd vesel dɛn. dis dכg (Kinase inhibitor) de go dayrekt to di kεnsar sεl dεm εn i de blכk di fכmeshכn fכ di bכdi vεsul dεm εn di sεl dεm we de sheb (Inhibits angiogenesis). Dɔn di sɛl dɛn nɔ gɛt ɔksijɛn ɛn blɔd ɛn di tumbu kin angri.
💬 Wetin na di bad bad tin we kin apin we pɔsin tek dɛn kansa pils ya?
Siriɔs sayd ɛfɛkt dɛn de (Blak Bɔks Wɔnin)! di big εn fכs prכblεm na ‘Hand-foot syndrome’, usay di fut in sכl dεm εn di an dεm kin rεd bad bad wan, swεla, εn di skin kin kכmכt εn i kin at. Risk de bak fɔ mek yu gɛt ay blɔd prɛshɔn (High BP), siriɔs dayarɛa (Diarrhea) ɛn liva damej (Liver toxicity). Dɛn fɔ du liva blɔd tɛst ɔltɛm we dɛn de tek dis mɛrɛsin.
` regorafenib, kansa, kansa mɛrɛsin, kolorektal kansa, GIST, liva kansa, stivarga, kansa tritmɛnt, sayd ɛfɛkt
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