Yu de tek mɛrɛsin fɔ mek yu kɔlɔstrel go dɔŋ? If na so, yu go mɔs de tek wan klas fɔ drɔgs we dɛn kɔl ‘statins’. Afta yu dɔn bigin dis mɛrɛsin, sɔmtɛm yu kin fil lɛk yu ed de tɔn, yu kin fɔgɛt tin, ɔ yu kin gɛt wetin wi kɔl ‘bren fɔg’? Dis na prɔblɛm we bɔku pipul dɛn gɛt. So tide, lɛ wi fɛn ɔl wetin i bi.
Fɔs, lɛ wi si, wetin na dis statin?
Fɔ tɔk am simpul wan, kɔlɔstrel na tin we tan lɛk waks ɛn ɔyl we de na wi blɔd. Wi bɔdi nid dis kɔlɔstrel fɔ bil sɛl ɛn mek ɔmon, bɔt if i bɔku pasmak, i nɔ fayn. εspεshali we di "bad" kכlestכl, כ LDL (Low-Density Lipoprotein) kכlestכl , hכy, i kin bכku pan di wכl dεm na wi bכdi vεsul dεm εn kכl dεm. Dis na big tin wae kin mek pɔrsin gɛt denja lɛk at atak ɛn strok.
Statin drɔgs de wok bay we dɛn de ridyus di bad bad LDL kɔlɔstrel we di liva de mek. So, i nɔ go bad fɔ kɔl dɛn mɛrɛsin ya impɔtant ɛn we de sev layf fɔ di wan dɛn we de pan denja fɔ gɛt at sik.
So dis ‘bren fog’ stori na tru?
Pan ɔl we dɛn kin tek statin as tin we rili sef fɔ bɔku pipul dɛn, lɛk ɛni mɛrɛsin, dɛn kin mek smɔl smɔl sayd ɛfɛkt dɛn. Fɔ ɛgzampul, di pen na di mɔsul dɛn, di liva we de pwɛl, ɛn ‘brɛn fɔg’, ɔ prɔblɛm wit mɛmori ɛn atɛnshɔn, na sɔm pan dɛn.
‘Brain Fog’ na stet we de mek pipul dɛn kɔnfyus ɛn kɔnfyus bad bad wan. Imajin, yu fɔgɛt usay yu put yu ki, sɔntɛm yu opin di frij ɛn lɛf di ki insay ɛn afta dat yu go luk fɔ am leta. Dis na de kayn tin wae kin apun na dis kayn sik.
Ivin di FDA na di US dɔn inklud mɛmori lɔs ɛn kɔnfyushɔn as "nɔ-siriɔs ɛn rivɛrsibl" sayd ifɛkt pan statin lɛbl. Kɔlɔstrel impɔtant fɔ mek wi bren wok fayn. infakt, 25% pan wi tכtal kכlestכl de na di bren. So i rizinɔs fɔ tink se if yu put di kɔlɔstrel dɔŋ wit statin, dat kin gɛt sɔm ifɛkt pan di bren.
Bɔt masta sabi pipul dɛn se nid nɔ de fɔ mek wi wɔri tumɔs bɔt dis. Bɔrku risach nɔr dɔn pruv yet se dis mɛrɛsin gɛt dairekt link bitwin dis mɛrɛsin ɛn di mɛmori lɔs.
Bɔrku tɛm, dɛn sayn ya kin bi sayn fɔ ɔda ɔndalayn mɛdikal kɔndishɔn. Ɛspɛshali we prɔblɛm wit mɛmori lɛk dis kin apin to pipul dɛm wae dɔn ol ɔr ol pipul dɛm, e kin bi wan fɔs sayn fɔ Alzaima sik.
So di fɔs tin we dɔktɔ kin tink na, "Dis rili bi bikɔs ɔf di mɛrɛsin? Ɔ ɔda prɔblɛm de?" Fɔ dat, dɛn kin rifer yu to nyurosaykayatrik spɛshal dɔktɔ fɔ mek dɛn chɛk yu.
Sɔprayz!
Na di ɔda say, sɔm risach dɔn sho se fɔ yuz statin kin ridyus di risk fɔ gɛt dis maynia sik, ɔr de dכn pan intɛlijεns ɛn mɛmori wae kin apun wae pɔrsin de ol. Wan stɔdi wae dɛn bin du fɔ 12 ia sho se pipul dɛm wae de tek bɔku statin nɔr kin gɛt dis maynia sik. So dɛn de du mɔ risach bɔt dis.
Wetin yu fɔ du if yu gɛt dɛn bad bad tin ya?
If yu de tek wan statin ɛn yu gɛt ‘bren fɔg’, mɔsul pen, ɔ ɛni ɔda tin we nɔ kɔmɔn, di impɔtant tin ɛn di wangren tin we yu fɔ du na fɔ tɛl yu dɔktɔ.
Nɔ ɛva stɔp fɔ tek yu mɛrɛsin wantɛm wantɛm we yu nɔ tɔk to yu dɔktɔ. Mɛmba se dɛn mɛrɛsin ya de protɛkt yu frɔm siriɔs prɔblɛm dɛn lɛk at atak ɛn strok.
Yu dɔktɔ go chɛk yu sik ɛn chenj yu tritmɛnt plan if nid de. I kin du dɛn tin ya:
- Fɔ stɔp di statin mɛrɛsin fɔ sɔm tɛm we yu de tek naw.
- Switch to difrɛn kayn statin.
- Fɔ ridyus di doz fɔ di mɛrɛsin.
Wetin na di ɔda tin dɛn we dɛn kin yuz fɔ mek statin?
Sɔntɛnde, if statin dɛn kɔntinyu fɔ mek yu gɛt sayd ɛfɛkt, yu dɔktɔ kin tɛl yu fɔ tek ɔda mɛrɛsin dɛn. Sɔm pan dɛn tin ya de dɔŋ ya.
| Kategori fɔ drɔgs | Di we aw pɔsin de wok | Ɛgzampul dɛn (brand nem dɛn) . |
|---|---|---|
| ACL Inhibitɔ dɛn | I de ridyus di we aw di liva de mek di kɔlɔstrel. Sɔm mɛrɛsin dɛn kin stɔp bak di kɔlɔstrel we de kɔmɔt na di smɔl intestin. | Nexletol (bempedoik asid), Nɛkslizet (bempedoik asid ɛn ɛzetimib) . |
| PCSK9 Inhibitɔ dɛn | Dis na injɛkshɔn dɛn. Dɛn nɔ de go insay di bren. Dɛn kin brok di bad LDL kɔlɔstrel we de na di blɔd ɛn mek dɛn pul am kwik kwik wan. | Alirokumab (Praluent), Ɛvolokumab (Rɛpatha) . |
Dɛn mɛrɛsin ya kin dia pas statin ɛn dɛn nɔ kin fayn fɔ ɔlman, so dis na disizhɔn we yu dɔktɔ go disayd.
Wetin ɔda tin yu nid fɔ no bɔt we yu de tek statin?
Fɔ mek yu nɔ gɛt bɔku prɔblɛm dɛn, tek tɛm bak wit dɛn pɔynt dɛn ya:
- Tek tɛm wit grep: Sɔm kemikal dɛn we de insay grep jus kin ambɔg di bɔdi in ebul fɔ brok di statin drɔgs. Yu nɔ nid fɔ stɔp grep ɔltogɛda, bɔt aks yu dɔktɔ ɔmɔs yu kin it/drink.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek: Sɔm mɛrɛsin kin miks wit statin ɛn mek yu gɛt sayd ɛfɛkt. Ɛgzampul dɛn:
- Mεdisin dεm fכ at ritm dizayd (e.g. Amiodarone) .
- Ɔda kɔlɔstrel mɛrɛsin dɛn (e.g., Gemfibrozil) .
- Drug dɛn we dɛn kin yuz fɔ mɛn HIV
- Sɔm antibayɔtik ɛn antifɔngal (e.g. Clarithromycin, Itraconazole) .
- Drug dεm we de sכpres di imyun (e.g. Cyclosporine) .
- Tek tɛm: Wan kɔmɔn sayd ɛfɛkt we statin kin gɛt na we yu mɔsul dɛn kin pen. If yu bigin fɔ du ɛksɛsayz we yu de yuz tranga wan wantɛm wantɛm we yu de pan dɛn, yu go mek yu mɔsul dɛn pwɛl mɔ ɛn mɔ. If yu na nyu pɔsin fɔ du ɛksɛsayz, bil di intensiti smɔl smɔl.
Mɛsej we dɛn kin kɛr go na os
- Statin na wan mɛrɛsin we rili impɔtant, we de sev layf, we de ridyus di risk fɔ gɛt at atak ɛn strok.
- ‘Bren fɔg’ na wan sayd ɛfɛkt we nɔ kin apin so ɔltɛm. Bɔku tɛm, i nɔ kin siriɔs ɛn i kin go we dɛn stɔp ɔ chenj di mɛrɛsin.
- De mɛmori prɔblɛm wae yu de gɛt kin bi bikɔs ɔf ɔda tin dɛm (ej, ɔda mɛdikal kɔndishɔn dɛm) pas fɔ statin mɛrɛsin.
- If yu gɛt ɛni sayd ɛfɛkt, di bɛst tin fɔ du na fɔ tɔk to yu dɔktɔ.
- Nɔ stɔp fɔ tek statin fɔ ɛni rizin if yu nɔ gɛt dɔktɔ advays. Di bɛnifit dɛn pas di prɔblɛm dɛn fa fawe.
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