Imajin se yu gɛt fiva, yu bɔdi de at, ɛn yu bigin fɔ tek mɛrɛsin we dɔktɔ gi yu. Wetin yu go du if, insay sɔm dez, sɔntɛm wan ɔ tu wik, yu gɛt rɛd spat dɛn na yu bɔdi wantɛm wantɛm, yu gɛt sos insay yu mɔt, na yu yay, ɛn na yu bɔdi, ɛn yu skin bigin fɔ blista ɛn pul lɛk se dɛn dɔn bɔn am? Dis na rili sik we de mek pɔsin fred, i rili denja, ɛn i nɔ kin apin so ɔltɛm. Tide wi go tɔk bɔt dis sik we dɛn kɔl Stevens-Johnson Syndrome (SJS). I rili impɔtant fɔ mek ɔlman no bɔt dis.
Wetin na SJS ɛn TEN? Wetin na di difrɛns bitwin dɛn tu tin ya?
Stevens-Johnson Syndrome (SJS) na wan bad bad aypasɛnsitiviti riakshɔn, bɔku tɛm to wan drɔg. I kin min se wi skin ɛn di mukɔs mɛmbran dɛn kin pwɛl, ɛn dis kin mek di sɛl dɛn day ɛn di skin kin kɔmɔt. di mכkus mεmbran dεm na di dilik, mכst mεmbran dεm we de layn wi mכt, nos, yay, jεnital, εn anus.
Wan ɔda kayn bad bad we de fɔ dis sik, we wi kɔl Toxic Epidermal Necrolysis (TEN) . Fɔ tɔk am simpul wan, SJS ɛn TEN tan lɛk tu say na di sem sik.
- SJS (Stevens-Johnson Syndrome): Insay dis kes , less dan 10% pan di bodi in skin safa de slo.
- TƐN (Toxic Epidermal Necrolysis): Dis na wan sik we rili siriɔs ɛn we kin mek pɔsin in layf de pan denja we pas 30% pan di bɔdi in skin kin lɔs.
Bikɔs dɛn tu tin ya rili siriɔs, di pɔsin fɔ go na ɔspitul , sɔntɛnde na intensiv kia yunit (ICU) ɔ bɔn yunit.
Udat kin gɛt dis sik pas ɔlman?
Pan ɔl we SJS kin apin pan ɛni ej, i kin apin mɔ pan pikin ɛn yɔŋ pipul dɛn we nɔ rich 30. I kin apin bak pan pipul dɛn we dɔn ol. SJS kin bɔku smɔl pan uman dɛn pas man dɛn.
Smɔl difrɛns de we yu luk di rizin:
- Di men tin we kin mek pikin dɛn gɛt SJS na di sik dɛn we kin gɛt sik lɛk nyumonia .
- Di men tin we kin mek pɔsin gɛt SJS/TEN pan big pipul dɛn na we dɛn kin gɛt alɛji to wan mɛrɛsin .
Wetin na di sayn dɛm fɔ SJS?
E fayn fɔ no bɔt dɛn sik ya bikɔs di kwik we yu no dɛn, na di mɔ yu kin go to tritmɛnt kwik kwik wan. Bɔrku tɛm, di sayn dɛm kin sho insay wan ɔr tri wik afta dɛn bigin fɔ trit am.
Di fɔs sayn dɛm na di kɔmɔn kol simptom dɛm lɛk fiva, bɔdi we de at, ed we de at, ɛn kɔf. Dis kin mek i nɔ izi fɔ no SJS insay di fɔs tɛm. Na da tɛm de nɔmɔ yu kin gɛt siriɔs sik dɛn na di skin.
Dis dɔŋ ya na di men sayn dɛm fɔ SJS.
| Di sayn we de sho se di sik de | Fɔ ɛksplen am simpul wan |
|---|---|
| Na bad bad pen na di skin | Fɔ fil pen we de bɔn so bad bad wan dat yu nɔ go ebul fɔ tɔch yu skin. |
| Fiva ɛn bɔdi de at | Di sayn dɛm na wae yu gɛt ay fiva, yu bɔdi de at, ɛn yu ed de at. |
| Rɛd spat ɛn pat dɛn | Rɛd spat ɔ lɛsin dɛn we kin bigin na di fes ɛn chɛst ɛn spre ɔlsay na di bɔdi. |
| Blisters ɛn wund dɛn | Blista ɛn pen we de na di skin, insay di mɔt, trot, yay, di bɔdi we de na di bɔdi, ɛn di rɛktum. |
| Skin we de pul di skin | Di blista dɛn kin bɔs ɛn di layt we de ɔp di skin kin kɔmɔt insay big big flɛks. |
| Spit ɔut saliva frɔm di mɔt | Drul bikɔs ɔf ɔlsa na yu mɔt, nɔ ebul fɔ kip yu mɔt lɔk. |
| Ay kɔntakt | Blista ɛn swel na di yay, we kin mek i nɔ izi fɔ opin di yay. |
| Pen we yu de pis we yu de pis | siriכs pen we yu de pis bikoz fכ blista di mכkus mεmbran dεm. |
Men kɔz ɛn di kayn drɔgs wae kin mek yu gɛt SJS
Di men tin we kin mek pɔsin gɛt SJS na we i gɛt alɛji to wan patikyula mɛrɛsin. Bɔt dis nɔ kin apin wit ɔl di drɔgs. Bɔku kayn drɔgs de we kin mek pɔsin gɛt SJS.
| Rizin | Tɔk bɔt |
|---|---|
| Alɛji to mɛrɛsin dɛn | Dis na di kɔz fɔ di mɔtalman we gɛt bɔku SJS ɛn TEN kes dɛm. |
| Infεkshכn dεm | Ɛspɛshali pan pikin dɛm, i kin kam wit infekshɔn dɛm lɛk Mycoplasma pneumonia, Herpes, ɛn Hepatitis A. |
| Ɔda rizin dɛn | Graft-versus-host disease, na wan kɔmplikɛshɔn we kin apin afta dɛn dɔn transplant bon mɛrɔ, vaysin (we nɔ kin apin so ɔltɛm), ɛn sɔm tɛm dɛn nɔ kin fɛn ɛni kɔz. |
Drugs wae gɛt ay risk fɔ mek yu gɛt SJS
- Antibacterial sulfa drugs: Sɔm kayn antibayɔtik.
- Anti-ɛpileptik drɔgs: Fɔ ɛgzampul, drɔgs lɛk `Fenytoin (Dilantin®)`, `Carbamazepine (Tegretol®)`, `Lamotrigine (Lamictal®)`, `Phenobarbital (Luminal®)`.
- Allopurinol: Na drɔg we dɛn kin yuz fɔ trit gaut ɛn sɔm kayn kidni ston (`Aloprim®`, `Zyloprim®`).
- Pen kil (NSAID): Na nכn-stεroyd pen kil lεk `Piroxicam (Feldene®)`, `Diclofenac (Cambia®, Flector®)`. Ɔda mɛrɛsin dɛn lɛk `Nevirapine (Viramune®)`.
- Ɔda Antibayɔtik: Sɔm ɔda kayn antibayɔtik kin mek dis sik bak.
Impɔtant: Nɔto ɔlman go gɛt SJS frɔm di mɛrɛsin dɛn we dɛn rayt ya. Bɔku bɔku pipul dɛn de yuz dɛn. Bɔt dɛn dɔn no se dɛn mɛrɛsin ya gɛt ay risk fɔ gɛt SJS. Nɔ ɛva stɔp fɔ tek mɛrɛsin we dɔktɔ gi yu bay we yu yuz dis atikul.
Diagnosis ɛn tritmɛnt fɔ di sik
If yu ɔ pɔsin we yu sabi gɛt dɛn sayn ya we wi dɔn tɔk bɔt, mɔ if yu jɔs bigin fɔ tek nyu mɛrɛsin, i impɔtant fɔ go wantɛm wantɛm na di Imejɛnsi Dipatmɛnt (ETU) na di ɔspitul we de nia yu .
Dɔktɔ dɛn kin no dis sik bay we dɛn:
- bay we yu de egzamin yu skin εn di mכkus mεmbran dεm (lεk mכt, yay).
- Na bay wae yu aks bɔt de lɛvɛl wae yu de fil pen.
- Bay wae yu luk di rεt wae di skin simptom dεm de spre εn aw dεn dכn spre.
- If nid de, dɛn kin tek smɔl pat pan di skin ɛn chɛk am (skin biopsy).
Tritmɛnt fɔ SJS
Di men gol dɛm fɔ tritmɛnt fɔ SJS na fɔ stɔp di mɛrɛsin we mek di sik, kɔntrol di sayn dɛm, fɔ mek dɛn nɔ gɛt prɔblɛm, ɛn ɛp di skin fɔ wɛl. Ɔspitul na mandatory fɔ dis.
Sɔm tritmɛnt dɛn de dɔŋ ya:
| Di we aw dɛn kin trit am | Tɔk bɔt |
|---|---|
| Fɔ stɔp fɔ yuz di mɛrɛsin we de mek pɔsin gɛt di sik | Dis na di fɔs ɛn impɔtant tin we wi fɔ du. Di drɔg we dɛn tink se de mek SJS, dɛn kin stɔp am wantɛm wantɛm. |
| Fɔ gi wata ɛn sɔl to di bɔdi | di skin we de kכl de mek bכku wata de lכs frכm di bכdi, so dεn de yuz IV wata fכ gi di wata we nid εn εlektrolayt dεm. |
| Tritmɛnt fɔ di skin | Dɛn kin kɔba di skin we wund wit spɛshal dresin dɛn we nɔ de adhesive, jɔs lɛk aw dɛn kin trit pɔsin we dɔn bɔn. |
| Fɔ gi yu tin fɔ it | I nɔ kin izi fɔ it bikɔs ɔf di mɔt sos. Bikɔs i kin tek bɔku ɛnaji fɔ mek i wɛl, dɛn kin gi it we gɛt bɔku kalori tru wan tiub we dɛn kin pas tru di nos insay di bɛlɛ (tube-feeding). |
| Kɔntrol di pen | Dis na sik we de mek pɔsin fil pen bad bad wan, so dɛn kin gi am strɔng mɛrɛsin fɔ mek pɔsin fil pen. |
| Spɛshal mɛdikal savis | Go to dɔktɔ we de mɛn yu skin ɛn if di yay afɛkt, go to dɔktɔ we de mɛn yu yay. |
Kɔmplikɛshɔn dɛm fɔ SJS ɛn ifɛkt dɛm afta yu dɔn wɛl
SJS na wan sik we rili siriɔs we kin ivin mek pɔsin day. Na lɛk 10% pan di wan dɛn we gɛt SJS ɛn te to 50% pan di wan dɛn we gɛt di kayn we we rili bad, we na TEN, kin day. Di men tin wae kin mek pɔrsin day na siriɔs prɔblɛm lɛk sepsis, nyumonia, ɛn bɔku ɔgan dɛm wae nɔr de woke fayn.
Ivin if di sik dɔn wɛl, sɔm pipul dɛn kin gɛt prɔblɛm fɔ lɔng tɛm.
- Skin de chenj: Dray skin, it, skin de chenj in kɔlɔ.
- Prɔblɛm na di yay: di yay dray, di yay nɔ kin fil fayn ɔltɛm, i nɔ kin si fayn, i nɔ kin izi fɔ luk layt (fotophobia).
- Ɔda tin dɛn: We yu de swet pasmak, yu lɔng de pwɛl, yu nel de lɔs ɔ yu nɔ de wok fayn, yu ia de lɔs, yu nɔ de te yu fayn.
I rili impɔtant: If yu gɛt di mɛrɛsin we mek yu gɛt SJS bak, di sɛkɔn tɛm di sik kin rili bad pas di fɔs wan. So, i impɔtant fɔ mɛmba di nem fɔ di mɛrɛsin we mek yu gɛt SJS ɛn ɔda kayn mɛrɛsin dɛn fɔ di res ɔf yu layf ɛn fɔ tɛl ɔl di dɔktɔ dɛn we yu si.
Mɛsej we dɛn kin kɛr go na os
- Stevens-Johnson Syndrome (SJS) na wan bad bad tin we kin mek pɔsin in layf de pan denja, ɛn bɔku tɛm na wan drɔg kin kam wit am.
- Di fɔs sayn dɛm na fiva ɛn bɔdi pen, bɔt leta i kin go bifo to rɛd pat dɛm we de mek yu fil pen, blista, ɛn skin we de pul.
- If yu gɛt dɛn sik ya afta yu dɔn bigin fɔ tek nyu mɛrɛsin, go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm ɛn nɔ de te.
- Di men tritmɛnt na fɔ no ɛn stɔp di mɛrɛsin we mek di sik, ɛn gi sɔpɔt kia na di ɔspitul.
- Mɛmba di nem fɔ di mɛrɛsin we mek yu gɛt SJS fɔ di res ɔf yu layf ɛn tɛl yu dɔktɔ bɔt am ɛvri tɛm we yu go fɔ tritmɛnt. Dis kin sev yu layf.
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