Pwɛl hat na wan sik wae kin rili tranga wae kin afɛkt ɔl tu di maynd ɛn di bɔdi. So we wi go to dɔktɔ ɛn bigin fɔ trit wi, wi kin gɛt di op se wi go ebul fɔ wɛl kwik kwik wan frɔm dis sik. Bɔt imajin, yu bin yuz wan kayn mɛrɛsin, bɔt i nɔ bin wok. Dɔn di dɔktɔ bigin fɔ tek ɔda kayn mɛrɛsin, ɛn dat nɔ bin wok lɛk aw dɛn bin de tink? No wɔd nɔ de fɔ tɔk bɔt di pwɛl at, fred, ɛn nɔ ebul fɔ ɛp yu we yu de fil, nɔto so? If yu dɔn gɛt dis kayn ɛkspiriɛns, nɔto yu wangren de. Tide wi de tɔk bɔt wan tɔpik we de afɛkt bɔku pipul dɛn, bɔt dɛn nɔ de tɔk bɔt am bɔku. Dat na pwɛl hat sik wae nɔr kin gɛt tritmɛnt.
Wetin na ‘Tritment-Resistant Depression’?
Fɔ tɔk am simpul wan, dis na wan kayn pwɛl hat sik. Bɔt di spɛshal tin na dat i nɔ kin wɛl izi wan wit di tritmɛnt dɛn we dɛn kin gɛt. Pan ɔl we nɔto wan difinishɔn de bitwin dɔktɔ dɛm, di opinion we ɔlman kin gri wit na dat if di sayn dɛm fɔ pwɛl hat nɔr de dɔŋ ivin afta yu tek at le tu kayn antidipreshan frɔm tu difrɛn klas dɛm na di rayt doz ɛn fɔ di rayt tɛm , dɛn kin kɔl di kɔndishɔn ‘Treatment-Resistant Depression’.
Tink bɔt am dis we. Yu dɔktɔ disayd se yu gɛt pwɛl hat ɛn bigin yu fɔ tek wan mɛrɛsin. fכ egzampl, wan Sεlektiv Sεrotonin Riuptek Inhibitor (SSRI) (e.g., Fluoxetine). Bɔt if yu nɔr fil fayn afta 6 to 8 wik, yu dɔktɔ go stɔp da mɛrɛsin de ɛn bigin yu fɔ tek ɔda mɛrɛsin, wan we de wok difrɛn we. fכ egzampl, wan Serotonin-Norepinephrine Riuptek Inhibitor (SNRI) (e.g., Venlafaxine כ Duloxetine). If da sɛkɔn mɛrɛsin de nɔr woke, yu dɔktɔ kin tink se yu gɛt Treatment-Resistant Depression.
Fɔ tɔk di kɔrɛkt tin, mɛrɛsin tan lɛk filta. If yu gɛt rilif frɔm di fɔs ɔ sɛkɔn doz fɔ di mɛrɛsin, yu nɔr gɛt pwɛl hat sik wae nɔr kin gɛt tritmɛnt. Bɔt if di filta nɔ mɛn di sik, dat min se wi nid difrɛn we fɔ du am.
Aw yu go no fɔ tru se dis sik de?
Dis nɔto sɔntin we pɔsin kin disayd fɔ du wan nɛt. Na sɔntin we dɛn nid fɔ du smɔl smɔl, wit bɔku peshɛnt. Yu dɔktɔ go fala sɔm tin dɛn bifo i kam fɔ no se yu gɛt dis sik.
Gi inof tɛm fɔ tek mɛrɛsin
Mɛrɛsin fɔ pwɛl hat kin tek tɛm fɔ wok. Pan ɔl we sɔm pipul dɛn kin notis smɔl difrɛns insay sɔm dez, i kin tek at le 6 to 8 wiks fɔ mek di ful ifɛkt we wan mɛrɛsin gɛt fɔ sho. So, i nɔ fayn fɔ bigin tek wan mɛrɛsin ɛn stɔp afta wan ɔ tu wiks de tink se, "Dis nɔ de wok." I rili impɔtant fɔ peshɛnt ɛn fala wetin yu dɔktɔ tɛl yu fɔ du.
Gi di kɔrɛkt doz
Dis na pɔynt bak we rili impɔtant. Sɔntɛnde, di dɔktɔ kin bigin fɔ tek mɛrɛsin wit smɔl doz. If i nɔ du di tin we i bin de tink se i go du, i nɔ de chenj di mɛrɛsin wantɛm wantɛm. Di fɔs tin we yu fɔ du na fɔ mek di mɛrɛsin we yu de yuz naw go ɔp smɔl smɔl. Sɔm pipul dɛn kin dɔn tek bɔku kayn mɛrɛsin, bɔt dɛn kin tek ɔl dɛn tin ya we dɛn nɔ tek bɔku.
Fɔ ɛgzampul, if yu kin gi 100 miligram pan wan mɛrɛsin fɔ gɛt di maksimal bɛnifit, yu nɔ go se di mɛrɛsin nɔ wok if yu gi am 50 miligram ɛn i nɔ wok. I rili impɔtant fɔ tray di maksimal ifɛktiv doz fɔ ɛni drɔg .
Lɛ wi luk dis tebul fɔ ɛksplen dis joyn smɔl mɔ.
| Stej | Wetin De Apin | Impɔtant Notis dɛn |
|---|---|---|
| Fɔs tɛm we yu tray fɔ du am (1st Antidipreshɔn Trial) | Di dɔktɔ kin gi yu mɛrɛsin we de pan wan pan di antidipreshan klas dɛm (e.g., SSRI). | - Alaw 6-8 wiks fɔ mek di mɛrɛsin wok. - Dɛn go inkrisayz di doz if nid de. - Tɔk to yu dɔktɔ bɔt di sayd ɛfɛkt dɛm. |
| Sɛkɔn tray fɔ du am (2nd Antidipreshɔn Trayal) | If di fɔs mɛrɛsin nɔ wok, dɛn kin stat ɔda mɛrɛsin frɔm difrɛn klas (e.g., SNRI). | - Alaw 6-8 wiks fɔ mek dis mɛrɛsin wok. - Na ya bak, dɛn kin ajɔst di doz if nid de. - I impɔtant fɔ mek yu nɔ panik ɛn fɔ peshɛnt. |
| Fɔ asɛs di tin we de apin (Chɛk) | If di sik nɔr bɛtɛ ivin afta yu tek dɛn tu mɛrɛsin ya di rayt doz ɛn fɔ di rayt tɛm, dɛn kin no se na ‘Treatment-Resistant Depression’. | - Dis nɔto di ɛnd. Dis na impɔtant infɔmeshɔn we dɛn go yuz fɔ no di nɛks tritmɛnt step dɛm. - Tɔk to di dɔktɔ bɔt di tin dɛn we yu go ebul fɔ du. |
Nɔ giv ɔp fɔ op! Dat na di tin we impɔtant pas ɔl.
Na nɔmal tin fɔ fil ebi ebi lod ɛn fred we yu yɛri di wɔd dɛn ‘dipreshɔn we nɔ de tek tritmɛnt.’ Yu kin tink se, "O, a nɔ go ɛva bɛtɛ." Bɔt wi se, duya nɔ giv ɔp op .
Fɔ no dis kɔndishɔn nɔr min se yu joyn dɔn dɔn. E jɔs min se yu nid tritmɛnt plan we difrɛn frɔm di ɔspitul, ɛn spɛshal to yu.
"Di tin we impɔtant pas ɔl na fɔ nɔ giv ɔp op. Bɔku tritmɛnt opshɔn dɛn de - we de ɛn we de kam - we kin rili mek difrɛns na pɔsin in layf." - Dɔktɔ Jɔn Kristal, Yale Skul fɔ Mɛdisin
Yu dɔktɔ go tɔk to yu bɔt sɔm ɔda tin dɛn we yu go ebul fɔ du na dis tɛm, lɛk:
- Augmentation: Ad ɔda kayn mɛrɛsin to di antidipreshan we de naw.
- Ɔda Tritmɛnt: Fɔ tink bɔt ɔda mɛrɛsin dɛn apat frɔm mɛrɛsin.
- Saykotɛrapi: Tɔk tɛrapi. Saykotɛrapi kin rili wok fayn we dɛn yuz am wit mɛrɛsin.
Dis ɔl go bi bay yu sik, di sayn dɛm, ɛn di mɛrɛsin histri. So di tin we impɔtant pas ɔl na fɔ tɔk fri wan ɛn ɔnɛs to yu dɔktɔ bɔt ɔltin . Tɛl am wetin yu de fil, wetin yu de fred, yu sayd ɛfɛkt, ɛn nɔ stɔp.
Mɛsej we dɛn kin kɛr go na os
- ‘Treatment-Resistant Depression’ na rial mεdikal kכndyushכn. I nɔto sɔntin we yu dɔn imajin ɔ yu fɔlt.
- Jɛnɛral wan, dɛn kin sɔspɛkt dis kɔndishɔn if nɔr impɔtant afta dɛn dɔn tek di rayt doz fɔ antidipreshan frɔm tu difrɛn klas dɛm fɔ mɛrɛsin fɔ inof tɛm, lɛk 6-8 wik.
- Di doz fɔ wan mɛrɛsin ɛn di tɛm we dɛn fɔ gi am rili impɔtant. If di smɔl doz nɔ de gi rizɔlt, i nɔ kin bi se di mɛrɛsin nɔ wok atɔl.
- Fɔ no dis sik nɔto di ɛnd. Na jɔs impɔtant tin fɔ du fɔ fɛn di tritmɛnt we go fayn fɔ yu.
- Di tin we impɔtant pas ɔl na fɔ nɔ giv ɔp ɛn fɔ tɔk to yu dɔktɔ ɔltɛm ɛn opin wan . Bɔku tin dɛn de we yu go ebul fɔ du fɔ ɛp yu.
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