Yu dɔktɔ dɔn gi yu Venetoclax fɔ wan kansa kɔndishɔn? If na so, i rili impɔtant fɔ mek yu no gud gud wan bɔt dis mɛrɛsin. Na bikɔs dis na wan mɛrɛsin we rili pawaful, we spɛshal. Tide, wi go tɔk rili simpul ɛn pɔlitiks bɔt wetin na dis mɛrɛsin ɛn wetin yu nid fɔ tek tɛm wit we yu de yuz am.
Us kayn mɛrɛsin dis? (Wetin na Venetoclax?)
Fɔ tɔk am simpul wan, Venetoclax na "targeted therapy." Dis min se dis drɔg de rili kleva fɔ tɔch sɔm patikyula prɔtin dɛn we de na di kansa sɛl dɛn, ɛn i de stɔp ɔ kil dɛn fɔ mek dɛn nɔ gro. I kin wok difrɛn we pas di kemotɛrapi we dɛn kin tek ɔltɛm.
Dɛn kin yuz dis mɛrɛsin mɔ fɔ mɛn kansa dɛn we gɛt fɔ du wit blɔd lɛk:
- Kronik Limfosaytik Lukimiya (CLL) .
- Smɔl Limfosaytik Limfoma (SLL) .
- Akyu Maylɔjɛnik Lukimiya (AML) .
Yu dɔktɔ kin tɛl yu dis mɛrɛsin bak fɔ ɔda sik dɛn.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu bigin fɔ tek Venetoclax, i rili impɔtant fɔ gi yu dɔktɔ kɔmplit diskripshɔn bɔt yu wɛlbɔdi kɔndishɔn. Mek shɔ se yu tɛl yu dɔktɔ if yu gɛt ɛni wan pan dɛn tin ya:
- Kidni ɔ liva sik: If yu gɛt ɛni kidni ɔ liva sik.
- Blɔd abnɔmal tin dɛm: If di lɛvɛl fɔ yurik asid na di blɔd go ɔp, ɔ if di lɛvɛl fɔ sɔl lɛk potashɔm, fɔsfɔr, ɛn kalsiɔm smɔl ɔ bɔku.
- Gout: If yu gɛt gaut.
- If dɛn dɔn schedul fɔ gɛt vaysin: If yu de plan fɔ gɛt vaysin jisnɔ, mɔ di layf vayrɔs vaysin.
- Alɛji: If yu gɛt alɛji fɔ Venetoclax ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- Bɛlɛ: If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu tink se yu gɛt bɛlɛ.
- If yu na mama we de gi pikin in bɛlɛ: If yu de gi yu pikin in bɛlɛ.
Bay dis infɔmeshɔn, yu dɔktɔ go disayd di doz fɔ di mɛrɛsin we dɛn go gi yu, di we aw dɛn go gi yu, ɛn di tin dɛn we yu fɔ tek tɛm wit.
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
Dis na pat we rili impɔtant. Fɔ fala dɛn instrɔkshɔn ya fɔ gɛt di bɛst pan di mɛrɛsin ɛn fɔ mek di sayd ɛfɛkt dɛn nɔ bɔku.
- Tek wit it: Tek dis tablɛt ɔltɛm wit it ɛn wan glas wata. Nɔ tek ɛmti bɛlɛ.
- Swɛla di tablɛt: Nɔ brok, krɔs, ɔ chew di tablɛt. Swɛla am ɔl.
- Nɔ it dɛn frut ya: Nɔ drink grep jus, it Sɛvil ɔrɛnj, ɔ stafruit we yu de tek dis mɛrɛsin. Dɛn tin ya kin chenj di we aw di mɛrɛsin de wok na di bɔdi.
- Tek am di rayt tɛm: Tray fɔ tek yu mɛrɛsin di sem tɛm ɛvride. Nɔ tek pas di mɔni we yu dɔktɔ tɛl yu fɔ tek.
- Nɔ stɔp fɔ tek yu mɛrɛsin if yu dɔktɔ nɔ advays yu fɔ ɛni rizin .
Mɛmba se na fɔ yu nɔmɔ dɛn gi dis mɛrɛsin. Nɔ ɛva sheb am wit ɛni ɔda pɔsin.
Wetin yu kin du if yu mis apɔntinmɛnt fɔ tek mɛrɛsin?
Imajin se yu fɔgɛt fɔ tek yu mɛrɛsin.
- If i pas 8 awa frɔm di las tɛm we yu tek di pil we yu mɛmba, tek am jɔs lɛk aw yu mɛmba.
- Bɔt if i dɔn pas 8 awa frɔm we yu las tek di doz, skip di doz we yu mis. Tek yu pil na yu rɛgyula tɛm di nɛks de.
- Nɔ ɛva tek dabl doz.
- If yu vɔmit afta yu dɔn tek di mɛrɛsin, nɔ tek ɔda pil. Tek di ɔspitul doz na di tɛm we dɛn dɔn sɛtul di nɛks de.
Tin dɛn we yu fɔ tek tɛm mɔ bɔt we yu de tek Venetoclax
Yu nid fɔ pe atɛnshɔn smɔl mɔ to yu bɔdi we yu de tek dis mɛrɛsin.
- Tumor Lysis Syndrome (TLS) Risk: Dis na smɔl kɔmplikɛt wɔd, bɔt i simpul: We Venetoclax de pwɛl di kansa sɛl dɛn kwik kwik wan, di tin dɛn we de insay dɛn sɛl dɛn de kin lik wantɛm wantɛm insay di blɔd. Dis kin afɛkt di kidni dɛn. I go mɔs bi se yu dɔktɔ go gi yu ɔda mɛrɛsin bifo yu bigin fɔ tek di mɛrɛsin fɔ mek dis nɔ apin.
- Drink bɔku wata: Wan pan di bɛst we fɔ ridyus di risk fɔ gɛt TLS na fɔ drink bɔku wata ɔl di de. Yu fɔ drink di wata we yu dɔktɔ tɛl yu fɔ drink (bɔku tɛm na 1.5 - 2 lita fɔ wan de).
- Blɔd tɛst: We yu de tek dis mɛrɛsin, yu dɔktɔ go ɔda fɔ mek dɛn du blɔd tɛst fɔ chɛk yu blɔd sɛl dɛn ɛn aw yu kidni de wok ɔltɛm. Nɔ skip dɛn tɛst ya.
- Protɛkt yusɛf frɔm infɛkshɔn: Dis mɛrɛsin kin mek yu bɔdi nɔ ebul fɔ fɛt di sik. Dat min se yu kin sik mɔ. So nɔ de nia pipul dɛn we gɛt fiva ɔ kol. If yu gɛt sɔm sayn dɛn lɛk fiva, kɔf, ɔ trot we de at, nɔ fɔ tek mɛrɛsin fɔ yusɛf ɛn tɛl yu dɔktɔ wantɛm wantɛm .
- Bεlε εn bεlε: Nɔ bεlε we yu de tek dis mεrεsin εn fכ 30 dez afta yu stכp am. Dɔn bak, nɔ gɛt bɛlɛ we yu de tek di mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp am.Nɔ gi pikin in bɛlɛ . Aks yu dɔktɔ fɔ no mɔ bɔt dis.
Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?
Lɛk ɛni mɛrɛsin, Venetoclax kin mek sɔm sayd ɛfɛkt dɛn. Sɔm pan dɛn tin ya siriɔs, ɛn ɔda wan dɛn kin kɔmɔn. De impɔtant tin na fɔ no bɔt dɛn sik ya ɛn tek akshɔn kwik if nid de.
| Sayd ɛfɛkt/simptom | Tɔk bɔt |
|---|---|
| Go to yu dɔktɔ ɔ di ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm. | |
| Siriɔs Alɛji Riakshɔn dɛn | Skin rash, it, swel na yu fes, lip ɔ tong, i nɔ izi fɔ blo. |
| Tumor laysis sindrom (TLS) simptom dεm | Vɔmit/nɔs, i nɔ izi fɔ blo, yu at nɔ de bit ɔltɛm, yu de urine dak, yu taya pasmak, yu de fil pen na yu mɔsul ɔ yu jɔyn. |
| Di sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, kɔf ɔltɛm, trot we de at, bɔn we yu de pis. |
| Di sayn dɛn we de sho se pɔsin de blɔd | Blak ɔ blɔd stɔl, rɛd ɔ dak brawn urine, vɔmit we tan lɛk kɔfi grɔn, rɛd spat na di skin, blɔd we nɔ kɔmɔn frɔm di nos ɔ gam. |
| If i kɔntinyu ɔ i de mɔna yu, tɛl yu dɔktɔ. | |
| Kɔmɔn sayd ɛfɛkt dɛn | Daya, kɔnstipɛshɔn, bɛlɛ pen, bak pen, ed pen, diziz, swel na yu anklɛ ɛn fut. |
If yu gɛt ɛni ɔda kayn sik we nɔ kɔmɔn we dɛn nɔ tɔk bɔt na dis list, tɔk to yu dɔktɔ bɔt dɛn bak.
Ɔda tin dɛm wae kin miks wit dis mɛrɛsin
Venetoclax kin intarakt wit ɔda mɛrɛsin, ɛbul mɛrɛsin, ɛn sɔm it dɛn. So tɛl yu dɔktɔ bɔt ɔltin we yu de tek —inklud di mɛrɛsin dɛn we yu de tek, di mɛrɛsin dɛn we yu nɔ de bay, vaytamɛn dɛn, ɛbul mɛrɛsin dɛn, ɛn sɔpɔtmɛnt dɛn. I impɔtant mɔ fɔ tɛl yu dɔktɔ if yu de tek ɛni wan pan dɛn mɛrɛsin ya:
- Antifungal mεdikeshכn dεm (e.g. Ketoconazole, Fluconazole) .
- Sɔm antibayɔtiks (e.g. Klarithromycin, Erythromycin) .
- Sɔm mɛrɛsin fɔ ay blɔd prɛshɔn ɛn at sik (e.g. Diltiazem, Verapamil, Carvedilol) .
- Mεdikeshכn dεm fכ antikonvulsant (e.g. Carbamazepine, Phenytoin) .
- Herbal prodak dɛm lɛk Sɛnt Jɔn wɔt
- Layf vayrɔs vaysin dɛn
Dis list nɔr kɔmplit, so i go fayn fɔ tɛl yu dɔktɔ bɔt ɔltin wae yu de tek.
Aw yu kin kip ɛn trowe di mɛrɛsin?
- Di say we dɛn de kip am: Kip am usay pikin ɛn animal dɛn we yu lɛk nɔ go ebul fɔ rich. Stɔr insay di ɔrijinal kɔntena, tayt klos, fa frɔm mɔstɔ ɛn ɔt pasmak, na rum tɛmpracha (dɔwn 30 digri sɛlshiɔs).
- Fɔ trowe am: Di we we sef fɔ trowe mɛrɛsin we dɔn pas ɔ we yu nɔ want na fɔ kɛr dɛn go na program fɔ tek mɛrɛsin bak na yu ɔspitul ɔ famasi. If dat nɔ pɔsibul, pul di pils dɛn na di bɔtul, miks dɛn wit sɔntin lɛk kɔfi grɔn we dɛn dɔn yuz, pusi dɔti, ɔ dɔti, put dɛn insay bag we dɛn kin sidɔm, ɛn trowe dɛn na dɔti. Nɔ ɛva flush dɛn dɔŋ di tɔylɛt.
Mɛsej we dɛn kin kɛr go na os
- Ɔltɛm tek Venetoclax tablɛt wit it ɛn wan glas wata. Nɔ brok, krɔs, ɔ chew di tablɛt.
- Nɔ it ɔ drink grep, Sɛvil ɔrɛnj, ɛn kumkwat we yu de tek dis mɛrɛsin.
- Drink bɔku wata ɔl di de, lɛk aw yu dɔktɔ advays yu. Dis rili impɔtant.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn ɛbul mɛrɛsin dɛn we yu de tek.
- Go to dɔktɔ wantɛm wantɛm if yu gɛt sayn dɛn fɔ se yu gɛt di sik ɔ yu gɛt sayn dɛn fɔ TLS, lɛk fiva ɛn kol.
- Nɔ stɔp fɔ tek di mɛrɛsin we yu nɔ gɛt dɔktɔ advays fɔ ɛni rizin.
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