Ensigo yo eya pituitary ekola ekisusse? (Hyperpituitarism) Ka twogere ku nsonga eno mu ngeri ennyangu!

Olabye enkyukakyuka ennene mu mubiri gwo mu bwangu? Oboolyawo weeyongedde okugejja amangu, ffeesi yo ekyuse oba ng’owulira ng’okooye olunaku lwonna ne bw’ofuna otulo otya? Ebintu bino tutera okwerabira, nga tulowooza nti bya bulijjo. Naye obadde okimanyi nti emabega w’ebimu ku bintu bino, wayinza okubaawo enkyukakyuka mu nkola y’akawuka akatono, naye nga kakulu nnyo mu bwongo bwaffe. Ekyo kye twogerako leero.

Ensigo eno ey’omubiri (pituitary gland) eyitibwa etya? Lwaki kikulu nnyo?

Teebereza omubiri gwo nga kkampuni ennene. Omukungu omukulu owa kkampuni eyo, bboosi afuga buli kimu, ye nseke y’omubiri (pituitary gland ) . Eno nnywanto ntono, eringa entangawuuzi, esangibwa wansi w’obwongo bwaffe, nga eringa cherry. Wadde nga ntono, ekola emirimu mingi. Eno y'ensonga lwaki oluusi kiyitibwa "master gland."

Mu ngeri ennyangu, efuga emirimu gy’endwadde endala ez’omubiri mu mubiri gwaffe. Ng’ekyokulabirako, endwadde z’ekibumba, endwadde z’ekibumba, n’enkola yaffe ey’okuzaala, gamba ng’enkwaso oba ensigo, bifugibwa obusimu obufulumizibwa endwadde z’omubiri (pituitary gland).

Nga bwe kiri ku thermostat mu nnyumba yaffe. Bulijjo erondoola ebbugumu mu nnyumba era n’ekuuma ebbugumu ku ddaala lye limu ng’ekoleeza/okuggyako AC oba heater, nedda? Mu ngeri y’emu, enseke y’omubiri (pituitary gland) erondoola buli kiseera obusimu obuli mu mubiri gwaffe era n’eweereza obubonero eri endwadde endala okufulumya obusimu obwetaagisa mu kiseera ekituufu.

Kale kino obulwadde bwa hyperpituitarism kye ki?

Mu ngeri ennyangu, Hyperpituitarism y’ennywanto y’omubiri eyayogeddwako waggulu bw’ekola ennyo, n’efulumya obusimu bungi mu musaayi gwaffe okusinga bwe kyetaagisa. Kiringa bboosi mu kkampuni ng’akola ekisusse n’atabula buli kimu.

Ebiseera ebisinga, kwe kugamba, ebitundu nga 99%, ekivaako kiba kizimba kitono, ekitali kya kookolo (benign). Mu ngeri y’obusawo, kino tukiyita obulwadde bwa pituitary adenoma . Ekizimba kino kisitula endwadde eno ne kigireetera okukola obusimu bungi okusinga bwe kisaanidde.

Obusimu obukolebwa enseke z’omubiri (pituitary gland) n’emirimu gyazo

Waliwo ebitundu ebikulu bisatu eby’endwadde ya pituitary gland. Buli kitundu kifulumya obusimu obw’enjawulo. Ka tulabe kiki kye bali ne kiki ekibatuukako.

Endwadde eziyinza okubaawo olw’endwadde z’omubiri (pituitary gland) ezikola ennyo

Embeera y’obulwadde ebaawo eyawukana okusinziira ku busimu ki obukolebwa ekisusse okuva mu nseke y’omubiri (pituitary gland). Katutunuulire embeera enkulu ezirabibwa.

• Obulwadde bwa Cushing: Singa obusimu bwa ACTH bukolebwa mu ngeri esukkiridde, omuwendo gwa cortisol mu mubiri gwaffe gweyongera nnyo. Kino kiyitibwa obulwadde bwa Cushing’s Syndrome.
• Acromegaly: Embeera eno ebaawo nga obusimu bw’okukula (GH) bukoleddwa ekisusse mu bukulu. Kino kireetera amagumba g’emikono, ebigere ne mu maaso okukula amanene mu ngeri etaali ya bulijjo. Singa kino kibaawo mu buto, kiyitibwa gigantism .
• Hyperthyroidism: Singa TSH esukkiridde ekolebwa (kino tekitera kubaawo), endwadde ya thyroid ekola ekisusse era omubiri n’ekola amangu.
• Prolactinoma: Ekizimba (adenoma) mu butoffaali obukola obusimu obuyitibwa prolactin kireeta okukola obusimu obususse. Kino kiyinza okukosa ennyo obulamu bw’okuzaala.

Bubonero ki obulaga endwadde zino?

Obubonero obujja ne buli emu ku mbeera zino bwa njawulo. Bw’oba ​​olina obubonero buno, kikulu nnyo okugenda ew’omusawo.

Embeera eno ekosa etya abaana?

Obulwadde bwa hyperpituitarism butono nnyo mu baana. Singa kibaawo, kitera okuva ku bulwadde obutono obuyitibwa pituitary adenoma. Ekika ky’ekizimba ekisinga okubeera mu baana kye kizimba ekikola prolactin (Prolactinomas).

• Ku bawala: Okulwawo okutuuka mu myaka gy’obuvubuka, okulekera awo okugenda mu nsonga (amenorrhea), n’enkwaso obutakola bulungi biyinza okubaawo.
• Abalenzi: Ebizimba ebinene (macroprolactinomas) bitera okuvaamu. Olw’okuba ebizimba bino binene, bisobola okunyigiriza obusimu mu bwongo ne kireeta okulumwa omutwe n’okulaba obuzibu. Era ziyinza okuvaako okulwawo okutuuka mu myaka gy’obuvubuka n’okulemererwa okukula.

Omusawo azuula atya obulwadde buno?

Bw’otubuulira obubonero bwo, omusawo ajja kusooka kukukebera bulungi. Oluvannyuma, bayinza okukola ebigezo ebiwerako okukakasa nti bazuuliddwa.

1. Okukebera omusaayi n’omusulo: Bino bijja kupima obusimu obuli mu musaayi gwo era nga kiyinzika okuba n’omusulo. Ng’ekyokulabirako, bajja kukebera obungi bw’obusimu bwo obwa prolactin, cortisol, n’obusimu bw’okukula.

2. Sikaani z’okukuba ebifaananyi:Singa wazuulibwa nti waliwo obutali bwa bulijjo mu busimu, bakola sikaani okukebera oba waliwo ekizimba mu pituitary. Sikaani esinga okukozesebwa ku kino ye sikaani ya MRI (Magnetic Resonance Imaging) . Ku muntu atasobola kukola MRI (e.g. omuntu alina ekyuma ekikuba omukka), CT (Computed Tomography) scan nayo eyinza okukolebwa.

3. Okukebera okw’enjawulo: Oluusi, okuzuula obulungi embeera nga Cushing’s syndrome, okukebera okw’enjawulo, gamba ng’okupima emiwendo gya cortisol mu ntuuyo, kiyinza okwetaagisa.

Obujjanjabi bwe buruwa?

Obujjanjabi bw’embeera eno businziira ku bintu ng’ekika ky’embeera gy’olina, obunene bw’ekizimba, n’obulamu bwo okutwalira awamu. Waliwo obujjanjabi obukulu busatu.

1. Eddagala

Ebiseera ebisinga, obujjanjabi obusooka buba bwa ddagala. Eddagala lino likozesebwa okukola:

• Okufuga emiwendo gy’obusimu.
• Oluusi okukendeeza ku bunene bw’ekizimba.
• Eddagala likola nnyo naddala ku prolactinoma, nga emiwendo gy’obusimu gidda mu mbeera eya bulijjo mu misango egisukka mu 80%.

2. Okulongoosa

Singa eddagala terisobola kufuga kizimba, oba ekizimba bwe kiba kinene ekimala okukosa okulaba, ekiddako kwe kulongoosa okuggyamu ekizimba.

• Okulongoosa okusinga okuyitibwa transsphenoidal adenomectomy . Kino kizingiramu okusala akatundu akatono ng’oyita mu nnyindo oba munda mu mimwa egya waggulu okutuuka ku nseke y’omubiri (pituitary gland) n’okuggyawo ekizimba nga tekikwonoona bwongo.
• Singa okulongoosa kuno kukolebwa omusawo alina obumanyirivu, obuwanguzi busukka mu 80%.

3. Obujjanjabi bw’amasannyalaze (Radiation Therapy).

Obujjanjabi bw’amasannyalaze bukozesebwa singa ekitundu ky’ekizimba kisigalawo oluvannyuma lw’okulongoosebwa, oba singa okulongoosebwa tekisoboka.

• Kino kizingiramu okutunuulira emisinde egy’amaanyi amangi okutuuka ku kizimba n’okusaanyaawo obutoffaali obwo.
• Enkola ez’omulembe nga stereotactic therapy zisobola okukendeeza ennyo ku kwonooneka kw’ebitundu ebiramu ebibyetoolodde.

Kisoboka okuba omulamu obulungi ng’olina embeera eno?

Yee, ddala. Embeera ezisinga eziva ku bulwadde bwa hyperpituitarism zisobola okuddukanyizibwa obulungi n’eddagala n’obujjanjabi obulala. Ekisinga obukulu kwe kufuna amagezi g’abasawo amangu ddala ng’obubonero bulabika n’okugoberera obujjanjabi bwennyini obulagiddwa. Embeera ezimu ziyinza okwetaagisa okuweebwa eddagala okumala ebbanga eddene oba okulabirirwa omusawo. Kyokka, abantu abasinga obungi bwe baba baddukanya obulungi, basobola okubeera n’obulamu obulungi, obw’essanyu, era obwa bulijjo.