Wansi w’obwongo bwaffe, waliwo akatundu akatono, naye nga kakulu nnyo. Tugiyita Ensigo ya Pituitary. Wadde nga ntono, yeeyisa nga bboosi omunene ow’omubiri gwaffe. Kifuga ebintu bingi ebikulu ennyo, gamba ng’okukula kwaffe, okukuba kw’omutima, n’obusobozi bw’okuzaala. Era y'egamba endwadde endala mu mubiri nti, "Okay, kati kola obusimu bwo." Eno y'ensonga lwaki tugiyita "Master Gland."
Kale, obutoffaali buno obw’endwadde z’omu lubuto bwe butandika okukula mu ngeri etaali ya bulijjo era nga tebufugibwa, tubuyita ekizimba ky’ennywanto. Naye abantu bangi kye batya wano oba kookolo. Mu butuufu, ebizimba ebisinga obungi mu pituitary si kookolo. Kookolo w’omu lubuto (pituitary cancer) tatera kubaawo nnyo. Wabula ebizimba bino ne bwe biba nga si bya kookolo, bisobola okuleeta obuzibu obw’amaanyi olw’obunene bwabyo (ebizimba ebinene) oba olw’okuba bikola obusimu obw’enjawulo omubiri bwe tegwetaaga (ebizimba ebikola). Kino kitera okujjanjabwa n’okulongoosa, eddagala oba obujjanjabi obw’amasannyalaze.
Lwaki ebizimba bino eby’omu nseke (pituitary tumors) bibaawo?
Mu butuufu abasawo n’okutuusa kati tebannaba kukakasa kiki ekivaako ebizimba bino. Oluusi wabaawo enkyukakyuka mu buzaale bw’obutoffaali bwa pituitary, naye kirabika kibaawo mu ngeri ya kimpowooze.
Kyokka waliwo embeera z’obuzaale ezimu ezireetera abantu abalina okukwatibwa ebizimba mu nseke. Ezimu ku bukwakkulizo buno mulimu:
- Carney complex: Eno mbeera ya buzaale etali ya bulijjo ereetera ebizimba bingi ebitali bya kookolo okutondebwa mu mubiri.
- Familia isolated pituitary adenoma (FIPA): Eno nayo mbeera etali ya bulijjo. Kivaako omubiri okubeera omunene okusinga ogwa bulijjo.
- Isolated family acromegaly: Kino kifaananako ne FIPA.
- Obulwadde bwa McCune-Albright syndrome: Embeera eno etatera kubaawo ereeta obuzibu mu magumba n’olususu.
- Multiple endocrine neoplasia, type I ne type IV (MEN1, MEN4): Embeera zino zisobola okuvaako ebizimba okukola mu nseke z’omubiri.
Obubonero obuva ku kukula kw’ekizimba
Ensigo y’omubiri (pituitary gland) esangibwa mu kifo ekitono ennyo wansi w’obwongo, okumpi ennyo n’obusimu bw’amaaso obutambuza obubaka wakati w’amaaso n’obwongo. Kale, ekizimba ekinene bwe kikula mu kifo kino ekitono, kitandika okusika ku bintu ebikyetoolodde. Kino kiyinza okuvaako obubonero obw’enjawulo.
Mu ngeri ennyangu, ekikolo ky’ekizibu kiri nti ekizimba bwe kikula, kinsika ebitundu ebikulu ebikyetoolodde, ne kivaamu ekifo ekitono.
Obubonero obukulu obuva ku mugotteko guno bwe bino:
- Omutwe: Omutwe gulumwa emirundi mingi, oluusi nga gulumwa nnyo.
- Ebizibu by’okulaba:Ebintu ng’okubulwa okulaba okw’okumpi n’okulaba emirundi ebiri naddala ng’otunudde butereevu mu maaso.
Ate era, singa ekizimba kino kinyigiriza ku nseke yennyini, obungi bw’obusimu obukolebwa endwadde eno buyinza okukendeera. Olwo, obubonero nga buno buyinza okubaawo:
- Ku basajja: okukula kw’amabeere, okuggwaamu enviiri mu maaso, n’obutakola bulungi mu kwegatta.
- Ku bakyala: okugenda mu nsonga ezitali za bulijjo oba nga ziyimiridde, okulekera awo okuyonsa nga tozaala mwana.
- Ku baana: Okulwawo okukula n’okukula mu by’okwegatta.
- Ebitera okubaawo: obwagazi obukendeera, okusesema, obutabeera bulungi mu lubuto, okukyuka mu buzito, n’okuwulira ennyogovu buli kiseera.
Obubonero obuva ku bizimba ebikola obusimu
Ebizimba ebimu (ebizimba ebikola) bikola obusimu obw’enjawulo omubiri gwe tegwetaaga. Obubonero obubaawo olwo businziira ku busimu ki obukolebwa mu kisusse. Ka tulabe engeri ekyo gye kikola.
| Obusimu obusinga okukolebwa | Embeera n’obubonero |
|---|---|
| Obusimu obuyitibwa adrenocorticotropic hormone (ACTH) . | Kino kifuga obusimu obuyitibwa cortisol. ACTH bwe yeeyongera, embeera eyitibwa Cushing’s syndrome ebaawo. Obubonero: Kyangu okunyiga, puleesa, ssukaali omungi, obubonero bwa kakobe oba pinki, ffeesi eyeetooloovu ennyo, obunafu bw’ebinywa, ebitundu by’omubiri ebigonvu n’okugaziwa mu maaso, ensingo n’omubiri. |
| Hormone y’okukula | Kino kifuga enkula y’omubiri, ssukaali n’okukozesa amasavu. Singa kino kyeyongera: Abaana: Okukula nga bawanvu nnyo okusinga ku bulijjo ( Gigantism ) . Abantu abakulu: Okugaziwa kw’amagumba ga ffeesi, emikono n’ebigere ( Acromegaly ) . Obubonero obulala: obulwadde bw’omutima, sukaali omungi mu musaayi, okulumwa ennyondo, okutuuyana ennyo. |
| Ekirungo kya Prolactin | Kino kisitula okukola amata g’amabeere mu bakyala. Singa kino kyeyongera: Ku bakyala: Amata g’amabeere gakulukuta nga tolina lubuto oba nga tonnazaala, obwagazi okukendeera, okugenda mu nsonga, okukaluubirirwa okufuna embuto. Ku basajja: ensigo okukendeera n’obutakola bulungi mu kwegatta. |
| Obusimu obusitula thyroid (TSH) . | Kino kigamba endwadde ya thyroid okukola obusimu. Bino bifuga okukula, ebbugumu n’okukuba kw’omutima. Singa TSH eba waggulu: Obubonero: Omutima gukuba mangu oba mu ngeri etaali ya bulijjo, okufulumya ekyenda emirundi mingi, obuzibu mu tulo, okukankana, okutuuyana ennyo, okugejja. |
Kino okisanga otya Omusawo?
Bw’ogenda ew’omusawo ng’alina obubonero buno, ajja kusooka kukubuuza ekibuuzo ekikwata ku bubonero bwo n’ebyafaayo by’obulamu bwo. Oluvannyuma, bajja kwekebejja omubiri.
Okugatta ku ekyo, kisoboka okukola ebigezo nga:
- Okukebera amaaso: Kebera olabe oba ekizimba kikosezza okulaba kwo.
- Okukebera obusimu: Kebera engeri obwongo bwo, omugongo n’obusimu gye bikolamu.
- Okukebera omusaayi n’omusulo: Kebera obusimu bwo olabe ddala bwe buli.
- Okukuba ebifaananyi: Okukakasa oba ekizimba kiriwo ng’otunula munda mu mubiri. Kino kitera okukolebwa nga bakozesa CT scan , era oluusi MRI scan eyinza okukolebwa.
Bujjanjabi ki obukolebwa ku kino?
Ebizimba ebisinga mu pituitary tebyetaagisa bujjanjabi. Kyokka, ekizimba kyo bwe kiba kyetaagisa okujjanjabibwa, enkola gy’olonze ejja kusinziira ku kika ky’ekizimba, obunene bwakyo, n’obulamu bwo okutwalira awamu.
Okuloongoosa
Buno bwe bujjanjabi obusinga okukozesebwa. Okuggyako nga kizimba ekikola prolactin, ebizimba ebirala ebisinga biggyibwamu nga balongoosebwa. Okulongoosa kuno, omusawo ayinza okusala mu nnyindo, okuyita mu kifo ekisala waggulu w’omumwa ogwa waggulu, oba okuyita mu kifo ekisala mu kiwanga. Okulongoosa kutera kukolebwa nga bayita mu kiwanga ku bizimba ebinene oba ku bizimba ebibunye mu ngeri enzibu.
Obujjanjabi bw’amasannyalaze (Radiation Therapy).
Obujjanjabi buno bukozesa X-rays ez’amaanyi amangi okusaanyaawo ekizimba. Obujjanjabi buno bwa mugaso singa ekizimba tekisobola kuggyibwawo ddala nga balongooseddwa, oba ng’ekizimba kikomyewo. Waliwo ebika by’obujjanjabi obw’amasannyalaze obw’enjawulo, okuva ku bujjanjabi obumu obwa ddoozi ennene (stereotactic radiosurgery) okutuuka ku bujjanjabi obwa ddoozi entono obuweebwa emirundi egiwerako mu wiiki okumala wiiki 4-6.
Eddagala
Okusinziira ku kika ky’ekizimba ky’olina, omusawo ayinza okusooka okugezaako eddagala. Naddala ekizimba kyo bwe kiba nga kivaamu ekirungo kya prolactin, eddagala liyinza okukendeeza ku busimu obwo ne liyamba ekizimba okukendeera. Eddagala era lya mugaso ku bizimba ebikola obusimu obukula n’okuddukanya embeera nga Cushing’s syndrome ne acromegaly.
Obubaka Obutwala Awaka
- Ebizimba ebisinga mu pituitary si kookolo, n’olwekyo totya mu ngeri eteetaagisa.
- Obubonero ng’okulumwa omutwe n’okukyuka mu kulaba buyinza okulabika okusinziira ku bunene bw’ekizimba. Obubonero era buyinza okulabika olw’enkyukakyuka mu busimu mu mubiri.
- Bw’oba olina obubonero nga buno, kikulu nnyo okulaba omusawo omukugu mu bwangu.
- Waliwo obujjanjabi obulungi ku kino, gamba ng’okulongoosa, obujjanjabi obw’amasannyalaze n’eddagala.
- Teesa ku bibuuzo byonna by’olina ku mbeera yo n’obujjanjabi bwo mu lwatu n’omusawo wo.
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